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The map label for this gene is dppA [H]

Identifier: 119774372

GI number: 119774372

Start: 1519261

End: 1520889

Strand: Reverse

Name: dppA [H]

Synonym: Sama_1235

Alternate gene names: 119774372

Gene position: 1520889-1519261 (Counterclockwise)

Preceding gene: 119774373

Following gene: 119774371

Centisome position: 35.32

GC content: 54.27

Gene sequence:

>1629_bases
ATGAATGCGCTGACAACCCGGCTTTATCGGTTTGCACTGCTGCCCCTTCTCGGTGGTTGGCTCGCGGCCTGTGGCCATCA
GCAATTGCCACCTGGGGTGGTTTACTGCTCCGAAGGTAACCCTGAATCATTCAATCCCCAGACAGTGACATCCGGCACCA
CCATAGATGCCACATCCCAGCAGATATACAGCCGCTTGGTGGATTACGACGCCGAAGAAGGCAAGATAGTACCTGCACTG
GCCGAACGTTGGAGCATCAGCGATGACGGCTTGGAGTATCGTTTCGTATTGCGCCAGGGCGTACAGTTTCATCATTCTGC
CAAGTTCACCCCCAGTCGCCCAATGAATGCCGACGATGTACTGTTTTCATTCCAGCGCATTCTCGATGATGAACATCCCT
TTCACTGGGTTTCCCGCAGCGGCTATCCGTTTTTCCAAAGCATCGATTTCGCCAATCAGGTTGCCTCGGTAACCAAGGCT
GGCGATAACGAGGTGGTGTTTAAACTCAATCACACTGATGCGTCGTTTTTATCGAATCTTGCCACGGACTTTGCCGTTAT
CCTGTCAGCCGAATACGCAGCCCAGCAACTGAGGGCCGGCACCCCCGAACAGCTCGACATCCAGGCAATAGGCACTGGAC
CGTTCCGGTTGGTGGAGTATGTGAAGAACGAATATATTCGCTACCGTCGCCACGAAGACTATTGGGGGAAGGCACCTGAA
ATAGACATGCTGGTGTACGACATCACCTCCAAGAGCACTGTGCGCTTATCAAAGCTCATCACGGGTGACTGCAGCGTGTC
CGCCCTGCCCAAAGCCGGTGAGCTTGATTTGATTGAGGCGCATCCTGAGCTTACGTTGGAGTCCAAGCCTGGCCTCAATG
TGGCCTTTTGGGCATTCAATACTCAAAAAGCGCCATTCAATGATGTGCGGGTACGCAAAGCCCTGTCACTGGCCATAGAT
AAGCGCAACATTCTTGCGGCCGTATACCAGGATACCGCTGTCGAGGCGCAAAGCCTGCTGCCGCCCTCCTCCTGGGCGTA
TGCCAGGGATTATGAACTCGACATTGACTATTCGCCTTCCAGAGCCATGACCCTGCTGGCCGATGCCGGCATTCGGAACC
TCAGCATTGACATCTGGGCCATGCCGGTAGCCAGGGCATACAACCCCAATGCCCTGAAAACAGCAGAACTTATTCAGGCC
GATTTGGCCAACATCGGGGTAAAGGCCAATATCATCAGCTATGACTGGTCGGTGTTTACCCAGAAATTGAATCAGAGCGA
TTATGACTCTGTGCTTATCGGCTGGAATGCCGACAACAGCGACCCTGACAACTTTTTCAGCCCACTATTGAGCTGCGCCT
CCATGGCATCGGGAAGTAACCGTTCACGTTGGTGTAACCCCGCATTTGACCAGCTGCTGTCCAAAGCCCGTTCGACCACC
GACAGATTGGAGCGCACCGCCCTCTATCAAGAGGCTCAGGCCACAGTTGCCAAGGAATTGCCCCTGTTTGCCTTCGCACA
CGCCAAGCGCTCGCTGGTGCACCGCAACAATATTCAGCATATGCCGGTAACGCCCTTTGGCGGTATTGCCTTCGCCGACA
TCCAGCCTGCAACGGAGGAGAAGAACTGA

Upstream 100 bases:

>100_bases
AAGAAATACAATTTACTGGATAAGGCATAAGTGGATTGCCGGGGGCGGCGAGCGGCTGTTAGAATCAACCATTACCGCTT
ACATCAATAACGATTCTTTA

Downstream 100 bases:

>100_bases
TGGGTATTTACCTTATCCGCAGACTGAACCTCTTTATCGCGACCTCCATATTGATGGTGAGCATTCTGTTTCTGGCAACC
AGCCAGTTTCCAACGGACAG

Product: peptide ABC transporter periplasmic peptide-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MNALTTRLYRFALLPLLGGWLAACGHQQLPPGVVYCSEGNPESFNPQTVTSGTTIDATSQQIYSRLVDYDAEEGKIVPAL
AERWSISDDGLEYRFVLRQGVQFHHSAKFTPSRPMNADDVLFSFQRILDDEHPFHWVSRSGYPFFQSIDFANQVASVTKA
GDNEVVFKLNHTDASFLSNLATDFAVILSAEYAAQQLRAGTPEQLDIQAIGTGPFRLVEYVKNEYIRYRRHEDYWGKAPE
IDMLVYDITSKSTVRLSKLITGDCSVSALPKAGELDLIEAHPELTLESKPGLNVAFWAFNTQKAPFNDVRVRKALSLAID
KRNILAAVYQDTAVEAQSLLPPSSWAYARDYELDIDYSPSRAMTLLADAGIRNLSIDIWAMPVARAYNPNALKTAELIQA
DLANIGVKANIISYDWSVFTQKLNQSDYDSVLIGWNADNSDPDNFFSPLLSCASMASGSNRSRWCNPAFDQLLSKARSTT
DRLERTALYQEAQATVAKELPLFAFAHAKRSLVHRNNIQHMPVTPFGGIAFADIQPATEEKN

Sequences:

>Translated_542_residues
MNALTTRLYRFALLPLLGGWLAACGHQQLPPGVVYCSEGNPESFNPQTVTSGTTIDATSQQIYSRLVDYDAEEGKIVPAL
AERWSISDDGLEYRFVLRQGVQFHHSAKFTPSRPMNADDVLFSFQRILDDEHPFHWVSRSGYPFFQSIDFANQVASVTKA
GDNEVVFKLNHTDASFLSNLATDFAVILSAEYAAQQLRAGTPEQLDIQAIGTGPFRLVEYVKNEYIRYRRHEDYWGKAPE
IDMLVYDITSKSTVRLSKLITGDCSVSALPKAGELDLIEAHPELTLESKPGLNVAFWAFNTQKAPFNDVRVRKALSLAID
KRNILAAVYQDTAVEAQSLLPPSSWAYARDYELDIDYSPSRAMTLLADAGIRNLSIDIWAMPVARAYNPNALKTAELIQA
DLANIGVKANIISYDWSVFTQKLNQSDYDSVLIGWNADNSDPDNFFSPLLSCASMASGSNRSRWCNPAFDQLLSKARSTT
DRLERTALYQEAQATVAKELPLFAFAHAKRSLVHRNNIQHMPVTPFGGIAFADIQPATEEKN
>Mature_542_residues
MNALTTRLYRFALLPLLGGWLAACGHQQLPPGVVYCSEGNPESFNPQTVTSGTTIDATSQQIYSRLVDYDAEEGKIVPAL
AERWSISDDGLEYRFVLRQGVQFHHSAKFTPSRPMNADDVLFSFQRILDDEHPFHWVSRSGYPFFQSIDFANQVASVTKA
GDNEVVFKLNHTDASFLSNLATDFAVILSAEYAAQQLRAGTPEQLDIQAIGTGPFRLVEYVKNEYIRYRRHEDYWGKAPE
IDMLVYDITSKSTVRLSKLITGDCSVSALPKAGELDLIEAHPELTLESKPGLNVAFWAFNTQKAPFNDVRVRKALSLAID
KRNILAAVYQDTAVEAQSLLPPSSWAYARDYELDIDYSPSRAMTLLADAGIRNLSIDIWAMPVARAYNPNALKTAELIQA
DLANIGVKANIISYDWSVFTQKLNQSDYDSVLIGWNADNSDPDNFFSPLLSCASMASGSNRSRWCNPAFDQLLSKARSTT
DRLERTALYQEAQATVAKELPLFAFAHAKRSLVHRNNIQHMPVTPFGGIAFADIQPATEEKN

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=503, Percent_Identity=43.7375745526839, Blast_Score=475, Evalue=1e-135,
Organism=Escherichia coli, GI1787551, Length=503, Percent_Identity=43.1411530815109, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1787052, Length=489, Percent_Identity=25.1533742331288, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1789887, Length=562, Percent_Identity=25.0889679715303, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787762, Length=503, Percent_Identity=25.4473161033797, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789397, Length=487, Percent_Identity=26.694045174538, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787495, Length=498, Percent_Identity=25.3012048192771, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87081878, Length=483, Percent_Identity=25.4658385093168, Blast_Score=115, Evalue=6e-27,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60399; Mature: 60399

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALTTRLYRFALLPLLGGWLAACGHQQLPPGVVYCSEGNPESFNPQTVTSGTTIDATSQ
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEECCCCEECHHHH
QIYSRLVDYDAEEGKIVPALAERWSISDDGLEYRFVLRQGVQFHHSAKFTPSRPMNADDV
HHHHHHHCCCCCCCEEEHHHHHHCCCCCCCCHHHHHHHHCCHHHCCCCCCCCCCCCHHHH
LFSFQRILDDEHPFHWVSRSGYPFFQSIDFANQVASVTKAGDNEVVFKLNHTDASFLSNL
HHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
ATDFAVILSAEYAAQQLRAGTPEQLDIQAIGTGPFRLVEYVKNEYIRYRRHEDYWGKAPE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
IDMLVYDITSKSTVRLSKLITGDCSVSALPKAGELDLIEAHPELTLESKPGLNVAFWAFN
CEEEEEEECCCCCEEEHHHHCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCEEEEEEEE
TQKAPFNDVRVRKALSLAIDKRNILAAVYQDTAVEAQSLLPPSSWAYARDYELDIDYSPS
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCC
RAMTLLADAGIRNLSIDIWAMPVARAYNPNALKTAELIQADLANIGVKANIISYDWSVFT
HHEEEEECCCCCEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEECHHHHH
QKLNQSDYDSVLIGWNADNSDPDNFFSPLLSCASMASGSNRSRWCNPAFDQLLSKARSTT
HHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
DRLERTALYQEAQATVAKELPLFAFAHAKRSLVHRNNIQHMPVTPFGGIAFADIQPATEE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCC
KN
CC
>Mature Secondary Structure
MNALTTRLYRFALLPLLGGWLAACGHQQLPPGVVYCSEGNPESFNPQTVTSGTTIDATSQ
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEECCCCEECHHHH
QIYSRLVDYDAEEGKIVPALAERWSISDDGLEYRFVLRQGVQFHHSAKFTPSRPMNADDV
HHHHHHHCCCCCCCEEEHHHHHHCCCCCCCCHHHHHHHHCCHHHCCCCCCCCCCCCHHHH
LFSFQRILDDEHPFHWVSRSGYPFFQSIDFANQVASVTKAGDNEVVFKLNHTDASFLSNL
HHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
ATDFAVILSAEYAAQQLRAGTPEQLDIQAIGTGPFRLVEYVKNEYIRYRRHEDYWGKAPE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
IDMLVYDITSKSTVRLSKLITGDCSVSALPKAGELDLIEAHPELTLESKPGLNVAFWAFN
CEEEEEEECCCCCEEEHHHHCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCEEEEEEEE
TQKAPFNDVRVRKALSLAIDKRNILAAVYQDTAVEAQSLLPPSSWAYARDYELDIDYSPS
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCC
RAMTLLADAGIRNLSIDIWAMPVARAYNPNALKTAELIQADLANIGVKANIISYDWSVFT
HHEEEEECCCCCEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEECHHHHH
QKLNQSDYDSVLIGWNADNSDPDNFFSPLLSCASMASGSNRSRWCNPAFDQLLSKARSTT
HHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
DRLERTALYQEAQATVAKELPLFAFAHAKRSLVHRNNIQHMPVTPFGGIAFADIQPATEE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCC
KN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]