Click here to switch to the map view.

The map label for this gene is glnS [H]

Identifier: 119774353

GI number: 119774353

Start: 1497161

End: 1498828

Strand: Direct

Name: glnS [H]

Synonym: Sama_1216

Alternate gene names: 119774353

Gene position: 1497161-1498828 (Clockwise)

Preceding gene: 119774352

Following gene: 119774355

Centisome position: 34.77

GC content: 53.6

Gene sequence:

>1668_bases
ATGAGTCACGTGGACAACGAAGTACGTCCCAGTAACTTCATTCGCAACATCATAGATGAAGATTTGGCCAGCGGTAAGCA
CACCAGTGTGCACACACGTTTTCCGCCGGAGCCAAACGGCTATCTGCACATTGGTCACGCCAAATCCATCTGCCTGAACT
TCGGTATCGCAGAGGATTACAAGGGCCAGTGCAACCTGCGTTTTGATGATACCAATCCTGAAAAAGAAGACATCGACTAT
GTCAACTCAATTCAGGAAGACGTTAAGTGGCTCGGATTCCAGTGGGATGGCGAGGTTCGCTATTCATCCAACTATTTCGA
TGAGCTTTACGGCTATGCAGTTGAATTGATCAACAAGGGCCTGGCTTATGTGTGTTTTCTCAATGCCGAGGAAACCCGCG
AATACCGTGGCACTCTGAAAGAGCCGGGCCGTAACAGCCCTTATCGTGACACCTCTCCCGAAGAAAACCTGGCGCTGTTT
GAAAAGATGCGCGACGGTGGCTTCAAAGAAGGTGAGTGCGTACTGCGTGCCAAAATCGATATGGCGTCGCCCTTTATGTG
TATGCGCGACCCTGTGATTTACCGCGTGAAGTTTGCCCATCACCACCAGACCGGTGACAAGTGGTGCATCTATCCGATGT
ACGACTTTACCCACTGTATTTCAGACGCGCTGGAAAACATCACCCATTCGCTGTGTACGCTGGAGTTCCAGGACAACCGT
CGTCTGTACGACTGGGTGCTGGATAACCTCAATGATTTCCAGGCGCCTAACCGTACCCGTCAGTACGAGTTTTCCCGTCT
GAATCTTGAATACACCCTGATGTCCAAGCGCAAGCTGAACGACTTGGTGGTACGTGGTCTGGTGTCCGGTTGGGACGACC
CTCGCATGCCAACCATCGCCGGTCTGCGTCGCCGTGGTTACACGCCAGCGTCTATCCGCGAGTTTTGTCAGCGCATTGGT
GTGACCAAGCAGGACAACCTGGTTGAAGTAGGCATGCTTGAAGCCTGTATTCGTGAAGACCTCAACGAAAATGCCCCACG
CGCCATGGCCGTTATTCGCCCTATTAAGGTGATCATCGAAAACTTCACCGCTCCAGAGCTTGAGTATGTGAAGGCGCCTG
TGCACCCCAACCTCGAAGAGATGGGTGAGCGTGAGCTGGCGTTCGGCCGTGAGATTTACATCGACGCCGCCGACTTCCGC
GAAGAAGCCAACAAACAGTACAAGCGTTTGGTGCTGGGCAAGGAAGTGCGTCTGCGTAATGCTTATGTGATTCGAGCCGA
GCGCTGCGAAAAAGATGCCGAAGGCAATGTCACCACCGTTTACTGCACCTATGATCCTGAGACTCTGGGCCAAAACCCAA
GTGATGGCCGTAAGGTGAAAGGTGTTATTCACTGGGTAGAAGCCACCACTGCGCTGCCTGCTGAGTTCCGCCTGTACGAT
CGCCTGTTCATCGATGCGAATCCGGCCGCTGCTGAGACCGTGGATGAAGTGCTGAACCCAGCCTCGTTGGAAGTGGTGCA
CGGCTTTGCTGAGGCGCCGCTGGCCAACGCCAAAGCCTCTCAGGCATATCAGTTTGAGCGTGAAGGCTACTTCTGCGCCG
ACAGCAAAGACTCGGCTCCGGGCAAGTTGGTGTTTAACCTGACGGTGGCTCTGCGCGAATCCTTCTGA

Upstream 100 bases:

>100_bases
TGAAGCGGGCAGTTTTTTATGTGCGGGCATTGTCAGCGGCAGGTTTCTGTAGGATCATGCAGGTTTTGAAAAATTTGCCA
CTGTTTGCAAGAGGAACTCC

Downstream 100 bases:

>100_bases
TTATTGAGCAGATAACTTAAAAGGCGCCAATGGCGCCTTTTTTTTCGGTGAAAAACTCTCTGTTGCTTTAAATTACTGCA
GCATTGGGCCAAAGCCCAGG

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSHVDNEVRPSNFIRNIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAEDYKGQCNLRFDDTNPEKEDIDY
VNSIQEDVKWLGFQWDGEVRYSSNYFDELYGYAVELINKGLAYVCFLNAEETREYRGTLKEPGRNSPYRDTSPEENLALF
EKMRDGGFKEGECVLRAKIDMASPFMCMRDPVIYRVKFAHHHQTGDKWCIYPMYDFTHCISDALENITHSLCTLEFQDNR
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVVRGLVSGWDDPRMPTIAGLRRRGYTPASIREFCQRIG
VTKQDNLVEVGMLEACIREDLNENAPRAMAVIRPIKVIIENFTAPELEYVKAPVHPNLEEMGERELAFGREIYIDAADFR
EEANKQYKRLVLGKEVRLRNAYVIRAERCEKDAEGNVTTVYCTYDPETLGQNPSDGRKVKGVIHWVEATTALPAEFRLYD
RLFIDANPAAAETVDEVLNPASLEVVHGFAEAPLANAKASQAYQFEREGYFCADSKDSAPGKLVFNLTVALRESF

Sequences:

>Translated_555_residues
MSHVDNEVRPSNFIRNIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAEDYKGQCNLRFDDTNPEKEDIDY
VNSIQEDVKWLGFQWDGEVRYSSNYFDELYGYAVELINKGLAYVCFLNAEETREYRGTLKEPGRNSPYRDTSPEENLALF
EKMRDGGFKEGECVLRAKIDMASPFMCMRDPVIYRVKFAHHHQTGDKWCIYPMYDFTHCISDALENITHSLCTLEFQDNR
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVVRGLVSGWDDPRMPTIAGLRRRGYTPASIREFCQRIG
VTKQDNLVEVGMLEACIREDLNENAPRAMAVIRPIKVIIENFTAPELEYVKAPVHPNLEEMGERELAFGREIYIDAADFR
EEANKQYKRLVLGKEVRLRNAYVIRAERCEKDAEGNVTTVYCTYDPETLGQNPSDGRKVKGVIHWVEATTALPAEFRLYD
RLFIDANPAAAETVDEVLNPASLEVVHGFAEAPLANAKASQAYQFEREGYFCADSKDSAPGKLVFNLTVALRESF
>Mature_554_residues
SHVDNEVRPSNFIRNIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAEDYKGQCNLRFDDTNPEKEDIDYV
NSIQEDVKWLGFQWDGEVRYSSNYFDELYGYAVELINKGLAYVCFLNAEETREYRGTLKEPGRNSPYRDTSPEENLALFE
KMRDGGFKEGECVLRAKIDMASPFMCMRDPVIYRVKFAHHHQTGDKWCIYPMYDFTHCISDALENITHSLCTLEFQDNRR
LYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVVRGLVSGWDDPRMPTIAGLRRRGYTPASIREFCQRIGV
TKQDNLVEVGMLEACIREDLNENAPRAMAVIRPIKVIIENFTAPELEYVKAPVHPNLEEMGERELAFGREIYIDAADFRE
EANKQYKRLVLGKEVRLRNAYVIRAERCEKDAEGNVTTVYCTYDPETLGQNPSDGRKVKGVIHWVEATTALPAEFRLYDR
LFIDANPAAAETVDEVLNPASLEVVHGFAEAPLANAKASQAYQFEREGYFCADSKDSAPGKLVFNLTVALRESF

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=530, Percent_Identity=47.7358490566038, Blast_Score=446, Evalue=1e-125,
Organism=Homo sapiens, GI62241042, Length=516, Percent_Identity=33.3333333333333, Blast_Score=266, Evalue=5e-71,
Organism=Escherichia coli, GI1786895, Length=549, Percent_Identity=74.3169398907104, Blast_Score=856, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=119, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=533, Percent_Identity=43.1519699812383, Blast_Score=411, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17511007, Length=524, Percent_Identity=33.206106870229, Blast_Score=249, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6324742, Length=566, Percent_Identity=40.6360424028269, Blast_Score=385, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6321192, Length=528, Percent_Identity=35.7954545454545, Blast_Score=297, Evalue=4e-81,
Organism=Drosophila melanogaster, GI17864488, Length=533, Percent_Identity=43.7148217636023, Blast_Score=419, Evalue=1e-117,
Organism=Drosophila melanogaster, GI24649466, Length=525, Percent_Identity=35.4285714285714, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24665321, Length=230, Percent_Identity=27.8260869565217, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 63731; Mature: 63600

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHVDNEVRPSNFIRNIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAEDY
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHEEEEECCCCCCC
KGQCNLRFDDTNPEKEDIDYVNSIQEDVKWLGFQWDGEVRYSSNYFDELYGYAVELINKG
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEECCEEEECCCHHHHHHHHHHHHHHCC
LAYVCFLNAEETREYRGTLKEPGRNSPYRDTSPEENLALFEKMRDGGFKEGECVLRAKID
CEEEEEECCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEC
MASPFMCMRDPVIYRVKFAHHHQTGDKWCIYPMYDFTHCISDALENITHSLCTLEFQDNR
CCCCCHHHCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCC
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVVRGLVSGWDDPRMPTIA
CHHHHHHCCCHHCCCCCCCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHH
GLRRRGYTPASIREFCQRIGVTKQDNLVEVGMLEACIREDLNENAPRAMAVIRPIKVIIE
HHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
NFTAPELEYVKAPVHPNLEEMGERELAFGREIYIDAADFREEANKQYKRLVLGKEVRLRN
CCCCCCHHHEECCCCCCHHHHCCHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEECC
AYVIRAERCEKDAEGNVTTVYCTYDPETLGQNPSDGRKVKGVIHWVEATTALPAEFRLYD
EEEEEHHHCCCCCCCCEEEEEEEECHHHCCCCCCCCCCEEHHEEEEHHHHCCCHHHEEEE
RLFIDANPAAAETVDEVLNPASLEVVHGFAEAPLANAKASQAYQFEREGYFCADSKDSAP
EEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHEEECCCCEEEECCCCCCC
GKLVFNLTVALRESF
CEEEEEEEEEEECCC
>Mature Secondary Structure 
SHVDNEVRPSNFIRNIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAEDY
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHEEEEECCCCCCC
KGQCNLRFDDTNPEKEDIDYVNSIQEDVKWLGFQWDGEVRYSSNYFDELYGYAVELINKG
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEECCEEEECCCHHHHHHHHHHHHHHCC
LAYVCFLNAEETREYRGTLKEPGRNSPYRDTSPEENLALFEKMRDGGFKEGECVLRAKID
CEEEEEECCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEC
MASPFMCMRDPVIYRVKFAHHHQTGDKWCIYPMYDFTHCISDALENITHSLCTLEFQDNR
CCCCCHHHCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCC
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVVRGLVSGWDDPRMPTIA
CHHHHHHCCCHHCCCCCCCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHH
GLRRRGYTPASIREFCQRIGVTKQDNLVEVGMLEACIREDLNENAPRAMAVIRPIKVIIE
HHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
NFTAPELEYVKAPVHPNLEEMGERELAFGREIYIDAADFREEANKQYKRLVLGKEVRLRN
CCCCCCHHHEECCCCCCHHHHCCHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEECC
AYVIRAERCEKDAEGNVTTVYCTYDPETLGQNPSDGRKVKGVIHWVEATTALPAEFRLYD
EEEEEHHHCCCCCCCCEEEEEEEECHHHCCCCCCCCCCEEHHEEEEHHHHCCCHHHEEEE
RLFIDANPAAAETVDEVLNPASLEVVHGFAEAPLANAKASQAYQFEREGYFCADSKDSAP
EEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHEEECCCCEEEECCCCCCC
GKLVFNLTVALRESF
CEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]