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The map label for this gene is hns [H]

Identifier: 119774305

GI number: 119774305

Start: 1425587

End: 1425979

Strand: Reverse

Name: hns [H]

Synonym: Sama_1168

Alternate gene names: 119774305

Gene position: 1425979-1425587 (Counterclockwise)

Preceding gene: 119774309

Following gene: 119774304

Centisome position: 33.12

GC content: 49.87

Gene sequence:

>393_bases
ATGAGCGAATTCCTCGAAATTTTGACCCACGGTCGTCGTCTGAAAGCAGCTGTTAAAGATTTGTCTTTGGATGAGCTGCG
TGATCTTGGCGCCAAACTCGAAAAAATCATTGTTGAGCGCGAAGCCGAAGCCGAAGAAGAATTGAAAGCCAACGCCGAGC
GTATTGCTAAAATTGAAGAAATCCGCAAGCAAATGGCCGAAATCGGTCTGTCTGTTGAAGATTTGGGCGTGACTGCAGCA
AAACCAGCCGCGAAGAAGCGCGCTCCCCGTCCACCAAAATATAAGATTGTGGTTGACGGTGAAGAAATCACCTGGACCGG
TCAGGGCCGCATGCCAACGGTATTCAAGAACGCCGTTGAAGGTGGCGCGTCCATGGATGACTTCCTCATCTAA

Upstream 100 bases:

>100_bases
AATAATTTCGGTTTTTTAATTGCAGATTGAATTATTTATTTCTATTATTTCATTCGATGTGAAAATTAACTTGTTATTTA
AATTGGGAAGCGAGTTTACC

Downstream 100 bases:

>100_bases
ACTGTCATCCAAATTAAAGGCCGATCTCCATCGGCCTTTTTTATTTCCTTTCGAAAACCTTTTTACATTTCTGTGCTGCC
ATTCTGCCCCGAATTCCGCT

Product: H-NS family DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MSEFLEILTHGRRLKAAVKDLSLDELRDLGAKLEKIIVEREAEAEEELKANAERIAKIEEIRKQMAEIGLSVEDLGVTAA
KPAAKKRAPRPPKYKIVVDGEEITWTGQGRMPTVFKNAVEGGASMDDFLI

Sequences:

>Translated_130_residues
MSEFLEILTHGRRLKAAVKDLSLDELRDLGAKLEKIIVEREAEAEEELKANAERIAKIEEIRKQMAEIGLSVEDLGVTAA
KPAAKKRAPRPPKYKIVVDGEEITWTGQGRMPTVFKNAVEGGASMDDFLI
>Mature_129_residues
SEFLEILTHGRRLKAAVKDLSLDELRDLGAKLEKIIVEREAEAEEELKANAERIAKIEEIRKQMAEIGLSVEDLGVTAAK
PAAKKRAPRPPKYKIVVDGEEITWTGQGRMPTVFKNAVEGGASMDDFLI

Specific function: Binds tightly to ds-DNA, increases its thermal stability and inhibits transcription [H]

COG id: COG2916

COG function: function code R; DNA-binding protein H-NS

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone-like protein H-NS family [H]

Homologues:

Organism=Escherichia coli, GI1789023, Length=134, Percent_Identity=41.7910447761194, Blast_Score=77, Evalue=4e-16,
Organism=Escherichia coli, GI1787489, Length=135, Percent_Identity=40.7407407407407, Blast_Score=75, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001801 [H]

Pfam domain/function: PF00816 Histone_HNS [H]

EC number: NA

Molecular weight: Translated: 14430; Mature: 14299

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFLEILTHGRRLKAAVKDLSLDELRDLGAKLEKIIVEREAEAEEELKANAERIAKIEE
CHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRKQMAEIGLSVEDLGVTAAKPAAKKRAPRPPKYKIVVDGEEITWTGQGRMPTVFKNAVE
HHHHHHHHCCCHHHCCCCCCCCHHHHCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHC
GGASMDDFLI
CCCCCCCCCC
>Mature Secondary Structure 
SEFLEILTHGRRLKAAVKDLSLDELRDLGAKLEKIIVEREAEAEEELKANAERIAKIEE
HHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRKQMAEIGLSVEDLGVTAAKPAAKKRAPRPPKYKIVVDGEEITWTGQGRMPTVFKNAVE
HHHHHHHHCCCHHHCCCCCCCCHHHHCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHC
GGASMDDFLI
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]