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The map label for this gene is dcp [H]

Identifier: 119774309

GI number: 119774309

Start: 1430689

End: 1432845

Strand: Reverse

Name: dcp [H]

Synonym: Sama_1172

Alternate gene names: 119774309

Gene position: 1432845-1430689 (Counterclockwise)

Preceding gene: 119774311

Following gene: 119774305

Centisome position: 33.27

GC content: 57.86

Gene sequence:

>2157_bases
ATGCATAAAAGCCTTATCGCCCTTGCCGTAGGCGGCGCGCTCTTGTTGGGCGGCTGCGCCCTTGGCCCGTCCGAAAGTGG
CGTAAACAATGGCGATGTAGCCACCGCTGTCGCCGTCATTGGTGCTGACAATCCCTTCTTCGCGCCAAGCGCACTGCAAT
ATCAGGCGCCCAACTTTGCCGCCATCAAGGACAGCCATTTTGAACCAGCGCTGTTGCAGGGCATTGCCGAGCACAAGGCT
GAGATCCTGGCCATTGCCAACAATCCTGAGCCAGCCACCTTTGAAAACACCCTGGTGGCCATGGAAAAAAGCGGCGCCCT
GCTGACCCGCACCTCCAAGGTGTTCTATAACCTGGCGGGCACCGACTCCAACCCTACCCTGCAAGCACTCCAGGCCAAGA
TGGCACCTTTGATGTCGGCTCACTCTGACGACATCAACCTGAACCCGACTCTGTTTGCCCGCATCGAAAGCCTGTACAAC
CAGCGCAACGACCTTGGGCTCACCAAAGAAGAAGTGCGCCTGATTGAGGTGTACCATCAGCGCTTTGTGATGGCTGGCGC
CAAGCTCACCGAAGCGCAGAAGACCCAAATTCGTGCCCTGAACGAAGAGCACTCCAAGCTGACCGATGAATTCCAGCAGC
GCCTGCGTCGCCTGACCAAGGAAATCGCCGTGGTGGTAAACAGCAAAGACGAGCTGGCGGGTCTGTCTGACAGCGCTATT
CGTATGGCGGCAGCCGATGCCAAGGCCGCAGGCCATGACGGCAAGTTCCTGCTGTCTATCACCAACACCACCCGTCAGCC
AGTGCTGGCACAGCTTGAAAACCGTGAGCTGCGTAAGCGGGTATTCGAAGCCTCTGCCAACCGTGGCCTTGAAGGCGAAA
ACGAAACTGCCTCTCTGGTTGCCCGTCTGGCACAGCTTCGCGCCGAACGCGCTGCCCTGCTGGGCTTTGACAACTGGGCC
AGCTATCGCCTGGCGCCACAAATGGCTGGCAGCCCTGAAGCCGTGTACGAGCTCTTTGGCACCATGGTGCCAAAAGTCGT
GGCCAACACCCGCAAAGAGGCCGCCGACATTCAGGCGATGATTGATAAAACCGGTGGCAATTTCGAGCTCAAGCCTTGGG
ACTGGGCCTTCTACGCCGAAAAAGTGCGTCAGGAAAAGTACGCCCTGGATGAAGAGAGCCTCAAGCCTTACTTCGAATTC
AACCGGGTGCTGGAAGATGGCGTGTTCTACACCATCAAGGAACTCTACGGCCTGACCATGAAGCCGCGCCCGGATCTGCC
GGTATACCACCCCGATGTAAAAGCCTATGAAATGTTCGATGAAGACGGCACCAGCCTGGCCATCTTCTACGCCGACTACT
TTGCCCGCGACGGCAAGCGTGGCGGCGCCTGGAAGAGCTCCTTCGTGGACCAGTCCGGTCTGCTGGGTAACAAGCCAGTG
GTTGTGAACGTGATGAACATCAAGAAGGCACCGGACGGCGAGCCGACCTTTGTCAGCTACGATGAAGTGACCACCATGTT
CCACGAAATGGGTCACGGCACCCACGGCATGCTGTCAAAGGTGAAATACCCAACGCTGGCAGGCACCAAGGTATCCCGCG
ACTTCGTTGAGTTCCCATCCACCTTCGAAGAAGACTGGGCAGCCCACCCCAAGGTGCTGGCCAACTACGCCCGTCACTAT
CAGAGTGGCGAGCCGCTGCCAAAGCCATTGCTGGACAAGTTGCTCAAGTCACGCAGCTTTAACCAGGGCTTCGACACCCT
GGAATACATGTCAGCCGCACTGGTAGACCTGGAATGGCACTCACTGAAAGCCGGTGACAGCCTCAAAGACGTTGCCAGCT
TCGAAGCCGCTGCGCTCAAGAAGCACGGTGTAGACATTGGAGCCGTGCCACCACGTTACCGCTCAACCTACTTCGCCCAC
GCCTTCCCGGGCGGCTACAGCGCCAGCTACTACGCCTACATGTGGTCTGAAATTTTGGCAGCCGACGCCTATGCCTATGT
GCAAACCCAGGGCGGTCTGAACCGTGAGATTGGTATGAAGTACCGCAAGACCATTCGTGAAGTGGGCAACAGCGTACCGC
CTATGGAAGCCTACATTAACTTCCGTGGTCAGGAGCCTACCACCGACGGTTTGCTGGAGCGCCGCGGCCTGAAATAA

Upstream 100 bases:

>100_bases
AGTGCCAGTTCCCACAACAATTCAGCCTTATTTAAGACCGCCTCGTTAGCCTAGCCAGTCATCAAAAAACCACAATCACA
ACAACAAGCAGGAAGAAACC

Downstream 100 bases:

>100_bases
TCGGCGCGACTTGCACCGGAGCAATACAAACCACAAAAAAAGCCGCTCAATTGAGCGGCTTTTTCCTGTCAGCTAAAGCG
GTTCAGCCTTTTCCTGCCTT

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MHKSLIALAVGGALLLGGCALGPSESGVNNGDVATAVAVIGADNPFFAPSALQYQAPNFAAIKDSHFEPALLQGIAEHKA
EILAIANNPEPATFENTLVAMEKSGALLTRTSKVFYNLAGTDSNPTLQALQAKMAPLMSAHSDDINLNPTLFARIESLYN
QRNDLGLTKEEVRLIEVYHQRFVMAGAKLTEAQKTQIRALNEEHSKLTDEFQQRLRRLTKEIAVVVNSKDELAGLSDSAI
RMAAADAKAAGHDGKFLLSITNTTRQPVLAQLENRELRKRVFEASANRGLEGENETASLVARLAQLRAERAALLGFDNWA
SYRLAPQMAGSPEAVYELFGTMVPKVVANTRKEAADIQAMIDKTGGNFELKPWDWAFYAEKVRQEKYALDEESLKPYFEF
NRVLEDGVFYTIKELYGLTMKPRPDLPVYHPDVKAYEMFDEDGTSLAIFYADYFARDGKRGGAWKSSFVDQSGLLGNKPV
VVNVMNIKKAPDGEPTFVSYDEVTTMFHEMGHGTHGMLSKVKYPTLAGTKVSRDFVEFPSTFEEDWAAHPKVLANYARHY
QSGEPLPKPLLDKLLKSRSFNQGFDTLEYMSAALVDLEWHSLKAGDSLKDVASFEAAALKKHGVDIGAVPPRYRSTYFAH
AFPGGYSASYYAYMWSEILAADAYAYVQTQGGLNREIGMKYRKTIREVGNSVPPMEAYINFRGQEPTTDGLLERRGLK

Sequences:

>Translated_718_residues
MHKSLIALAVGGALLLGGCALGPSESGVNNGDVATAVAVIGADNPFFAPSALQYQAPNFAAIKDSHFEPALLQGIAEHKA
EILAIANNPEPATFENTLVAMEKSGALLTRTSKVFYNLAGTDSNPTLQALQAKMAPLMSAHSDDINLNPTLFARIESLYN
QRNDLGLTKEEVRLIEVYHQRFVMAGAKLTEAQKTQIRALNEEHSKLTDEFQQRLRRLTKEIAVVVNSKDELAGLSDSAI
RMAAADAKAAGHDGKFLLSITNTTRQPVLAQLENRELRKRVFEASANRGLEGENETASLVARLAQLRAERAALLGFDNWA
SYRLAPQMAGSPEAVYELFGTMVPKVVANTRKEAADIQAMIDKTGGNFELKPWDWAFYAEKVRQEKYALDEESLKPYFEF
NRVLEDGVFYTIKELYGLTMKPRPDLPVYHPDVKAYEMFDEDGTSLAIFYADYFARDGKRGGAWKSSFVDQSGLLGNKPV
VVNVMNIKKAPDGEPTFVSYDEVTTMFHEMGHGTHGMLSKVKYPTLAGTKVSRDFVEFPSTFEEDWAAHPKVLANYARHY
QSGEPLPKPLLDKLLKSRSFNQGFDTLEYMSAALVDLEWHSLKAGDSLKDVASFEAAALKKHGVDIGAVPPRYRSTYFAH
AFPGGYSASYYAYMWSEILAADAYAYVQTQGGLNREIGMKYRKTIREVGNSVPPMEAYINFRGQEPTTDGLLERRGLK
>Mature_718_residues
MHKSLIALAVGGALLLGGCALGPSESGVNNGDVATAVAVIGADNPFFAPSALQYQAPNFAAIKDSHFEPALLQGIAEHKA
EILAIANNPEPATFENTLVAMEKSGALLTRTSKVFYNLAGTDSNPTLQALQAKMAPLMSAHSDDINLNPTLFARIESLYN
QRNDLGLTKEEVRLIEVYHQRFVMAGAKLTEAQKTQIRALNEEHSKLTDEFQQRLRRLTKEIAVVVNSKDELAGLSDSAI
RMAAADAKAAGHDGKFLLSITNTTRQPVLAQLENRELRKRVFEASANRGLEGENETASLVARLAQLRAERAALLGFDNWA
SYRLAPQMAGSPEAVYELFGTMVPKVVANTRKEAADIQAMIDKTGGNFELKPWDWAFYAEKVRQEKYALDEESLKPYFEF
NRVLEDGVFYTIKELYGLTMKPRPDLPVYHPDVKAYEMFDEDGTSLAIFYADYFARDGKRGGAWKSSFVDQSGLLGNKPV
VVNVMNIKKAPDGEPTFVSYDEVTTMFHEMGHGTHGMLSKVKYPTLAGTKVSRDFVEFPSTFEEDWAAHPKVLANYARHY
QSGEPLPKPLLDKLLKSRSFNQGFDTLEYMSAALVDLEWHSLKAGDSLKDVASFEAAALKKHGVDIGAVPPRYRSTYFAH
AFPGGYSASYYAYMWSEILAADAYAYVQTQGGLNREIGMKYRKTIREVGNSVPPMEAYINFRGQEPTTDGLLERRGLK

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=594, Percent_Identity=28.7878787878788, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI14149738, Length=647, Percent_Identity=29.0571870170015, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI156105687, Length=412, Percent_Identity=27.1844660194175, Blast_Score=156, Evalue=6e-38,
Organism=Escherichia coli, GI1787819, Length=675, Percent_Identity=46.3703703703704, Blast_Score=643, Evalue=0.0,
Organism=Escherichia coli, GI1789913, Length=686, Percent_Identity=31.3411078717201, Blast_Score=352, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI32565901, Length=449, Percent_Identity=25.1670378619154, Blast_Score=86, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319793, Length=608, Percent_Identity=26.1513157894737, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6322715, Length=476, Percent_Identity=23.5294117647059, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21356111, Length=450, Percent_Identity=24.2222222222222, Blast_Score=162, Evalue=7e-40,
Organism=Drosophila melanogaster, GI20129717, Length=410, Percent_Identity=27.8048780487805, Blast_Score=152, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 79442; Mature: 79442

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKSLIALAVGGALLLGGCALGPSESGVNNGDVATAVAVIGADNPFFAPSALQYQAPNFA
CCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEEEEEECCCCCCCCCCCEECCCCEE
AIKDSHFEPALLQGIAEHKAEILAIANNPEPATFENTLVAMEKSGALLTRTSKVFYNLAG
EECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEEHHHHEEEECC
TDSNPTLQALQAKMAPLMSAHSDDINLNPTLFARIESLYNQRNDLGLTKEEVRLIEVYHQ
CCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHCCCCCHHHHHHHHHHHH
RFVMAGAKLTEAQKTQIRALNEEHSKLTDEFQQRLRRLTKEIAVVVNSKDELAGLSDSAI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHCCCCHHHH
RMAAADAKAAGHDGKFLLSITNTTRQPVLAQLENRELRKRVFEASANRGLEGENETASLV
HHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ARLAQLRAERAALLGFDNWASYRLAPQMAGSPEAVYELFGTMVPKVVANTRKEAADIQAM
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDKTGGNFELKPWDWAFYAEKVRQEKYALDEESLKPYFEFNRVLEDGVFYTIKELYGLTM
HHCCCCCEECCCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHCCHHHHHHHHHCCCC
KPRPDLPVYHPDVKAYEMFDEDGTSLAIFYADYFARDGKRGGAWKSSFVDQSGLLGNKPV
CCCCCCCCCCCCCHHHHEECCCCCEEEEEEEHHHHCCCCCCCCHHHHHCCCCCCCCCCCE
VVNVMNIKKAPDGEPTFVSYDEVTTMFHEMGHGTHGMLSKVKYPTLAGTKVSRDFVEFPS
EEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHCCC
TFEEDWAAHPKVLANYARHYQSGEPLPKPLLDKLLKSRSFNQGFDTLEYMSAALVDLEWH
HHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHH
SLKAGDSLKDVASFEAAALKKHGVDIGAVPPRYRSTYFAHAFPGGYSASYYAYMWSEILA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHCCEEEECCCCCCCCHHHHHHHHHHHH
ADAYAYVQTQGGLNREIGMKYRKTIREVGNSVPPMEAYINFRGQEPTTDGLLERRGLK
HHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHEEECCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MHKSLIALAVGGALLLGGCALGPSESGVNNGDVATAVAVIGADNPFFAPSALQYQAPNFA
CCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEEEEEECCCCCCCCCCCEECCCCEE
AIKDSHFEPALLQGIAEHKAEILAIANNPEPATFENTLVAMEKSGALLTRTSKVFYNLAG
EECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEEHHHHEEEECC
TDSNPTLQALQAKMAPLMSAHSDDINLNPTLFARIESLYNQRNDLGLTKEEVRLIEVYHQ
CCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHCCCCCHHHHHHHHHHHH
RFVMAGAKLTEAQKTQIRALNEEHSKLTDEFQQRLRRLTKEIAVVVNSKDELAGLSDSAI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHCCCCHHHH
RMAAADAKAAGHDGKFLLSITNTTRQPVLAQLENRELRKRVFEASANRGLEGENETASLV
HHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ARLAQLRAERAALLGFDNWASYRLAPQMAGSPEAVYELFGTMVPKVVANTRKEAADIQAM
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDKTGGNFELKPWDWAFYAEKVRQEKYALDEESLKPYFEFNRVLEDGVFYTIKELYGLTM
HHCCCCCEECCCCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHCCHHHHHHHHHCCCC
KPRPDLPVYHPDVKAYEMFDEDGTSLAIFYADYFARDGKRGGAWKSSFVDQSGLLGNKPV
CCCCCCCCCCCCCHHHHEECCCCCEEEEEEEHHHHCCCCCCCCHHHHHCCCCCCCCCCCE
VVNVMNIKKAPDGEPTFVSYDEVTTMFHEMGHGTHGMLSKVKYPTLAGTKVSRDFVEFPS
EEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHCCC
TFEEDWAAHPKVLANYARHYQSGEPLPKPLLDKLLKSRSFNQGFDTLEYMSAALVDLEWH
HHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHH
SLKAGDSLKDVASFEAAALKKHGVDIGAVPPRYRSTYFAHAFPGGYSASYYAYMWSEILA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHCCEEEECCCCCCCCHHHHHHHHHHHH
ADAYAYVQTQGGLNREIGMKYRKTIREVGNSVPPMEAYINFRGQEPTTDGLLERRGLK
HHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHEEECCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]