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The map label for this gene is rnhB

Identifier: 119774290

GI number: 119774290

Start: 1403337

End: 1403957

Strand: Direct

Name: rnhB

Synonym: Sama_1153

Alternate gene names: 119774290

Gene position: 1403337-1403957 (Clockwise)

Preceding gene: 119774289

Following gene: 119774291

Centisome position: 32.59

GC content: 58.29

Gene sequence:

>621_bases
ATGGCGGTGTATAAAAATCTTAGCCCAGAGCAAACCGTGCTGCTGCAACAGGGACGGGTCGCCGGCGTTGATGAAGTGGG
CCGTGGCCCGCTGGTGGGCGATGTGGTGACCGCTGCGGTTATTCTGGATCCAAACAAGCCCATTGCTGGCTTGAATGACT
CAAAGAAGCTCACCGAGAAAAAGCGCGACGCACTTTATCTTGAGATTATGGATAAGGCGCTGGCGGTGTCGGTGGGCCGT
GCCAGCCCAACTGAAATCGACGAGCTTAATATTCTCCACGCGACCATGCTCGCGATGCAGCGAGCCGTTGCCGGACTGAC
GATTGTTCCCGAGTCCGTCCTGGTGGATGGCAACCGAACGCCGGATTTTGGTGTACCTGCCCATGCGGTAGTCAAAGGCG
ATGGCCTGATAGCCGCTATCAGCGCCGCTTCTGTCATTGCCAAAGTCACCCGTGACCGTGAGATGGGAGAGCTGGATGCC
CGGTATCCCCAGTACGGCTTTGCCGGGCACAAGGGATACCCAACCAAGGCACACTTTGAGGCGATAAGTGCCCATGGGGT
GCTCGCGGAGCACAGGCGCAGTTTTCGTCCGGTGCGCGAGTGGTTGGAGGCTAACAGCTGA

Upstream 100 bases:

>100_bases
AAAACCTCAGGCAAAATGCCAGCGAGCGGGCTGCCGATGCGGTCGATGTGCTGATTGGTGCCAATGCGCCACATGGCCGC
AGCTCCAATGAGGTGGGTTG

Downstream 100 bases:

>100_bases
ATCCGCAAAATCAAAAAGCAGCCTAGGCTGCTTTTTGATTTTGGTAATATGGGGTAACGGCGGATTAATGGGCGAGCGCC
CAGTTAAGCCTTTTGTTGAC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MAVYKNLSPEQTVLLQQGRVAGVDEVGRGPLVGDVVTAAVILDPNKPIAGLNDSKKLTEKKRDALYLEIMDKALAVSVGR
ASPTEIDELNILHATMLAMQRAVAGLTIVPESVLVDGNRTPDFGVPAHAVVKGDGLIAAISAASVIAKVTRDREMGELDA
RYPQYGFAGHKGYPTKAHFEAISAHGVLAEHRRSFRPVREWLEANS

Sequences:

>Translated_206_residues
MAVYKNLSPEQTVLLQQGRVAGVDEVGRGPLVGDVVTAAVILDPNKPIAGLNDSKKLTEKKRDALYLEIMDKALAVSVGR
ASPTEIDELNILHATMLAMQRAVAGLTIVPESVLVDGNRTPDFGVPAHAVVKGDGLIAAISAASVIAKVTRDREMGELDA
RYPQYGFAGHKGYPTKAHFEAISAHGVLAEHRRSFRPVREWLEANS
>Mature_205_residues
AVYKNLSPEQTVLLQQGRVAGVDEVGRGPLVGDVVTAAVILDPNKPIAGLNDSKKLTEKKRDALYLEIMDKALAVSVGRA
SPTEIDELNILHATMLAMQRAVAGLTIVPESVLVDGNRTPDFGVPAHAVVKGDGLIAAISAASVIAKVTRDREMGELDAR
YPQYGFAGHKGYPTKAHFEAISAHGVLAEHRRSFRPVREWLEANS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=183, Percent_Identity=71.0382513661202, Blast_Score=258, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_SHEAM (A1S4Q4)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927030.1
- ProteinModelPortal:   A1S4Q4
- SMR:   A1S4Q4
- STRING:   A1S4Q4
- GeneID:   4603405
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1153
- NMPDR:   fig|326297.7.peg.1085
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   A1S4Q4
- ProtClustDB:   PRK00015
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 22114; Mature: 21982

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYKNLSPEQTVLLQQGRVAGVDEVGRGPLVGDVVTAAVILDPNKPIAGLNDSKKLTEK
CCCCCCCCCHHHHHHHCCCCCCHHHCCCCCCHHHHHEEEEEECCCCCCCCCCCHHHHHHH
KRDALYLEIMDKALAVSVGRASPTEIDELNILHATMLAMQRAVAGLTIVPESVLVDGNRT
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCHHEEECCCCC
PDFGVPAHAVVKGDGLIAAISAASVIAKVTRDREMGELDARYPQYGFAGHKGYPTKAHFE
CCCCCCCEEEEECCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
AISAHGVLAEHRRSFRPVREWLEANS
HHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVYKNLSPEQTVLLQQGRVAGVDEVGRGPLVGDVVTAAVILDPNKPIAGLNDSKKLTEK
CCCCCCCCHHHHHHHCCCCCCHHHCCCCCCHHHHHEEEEEECCCCCCCCCCCHHHHHHH
KRDALYLEIMDKALAVSVGRASPTEIDELNILHATMLAMQRAVAGLTIVPESVLVDGNRT
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCHHEEECCCCC
PDFGVPAHAVVKGDGLIAAISAASVIAKVTRDREMGELDARYPQYGFAGHKGYPTKAHFE
CCCCCCCEEEEECCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
AISAHGVLAEHRRSFRPVREWLEANS
HHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA