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The map label for this gene is dapD

Identifier: 119774273

GI number: 119774273

Start: 1384757

End: 1385581

Strand: Reverse

Name: dapD

Synonym: Sama_1136

Alternate gene names: 119774273

Gene position: 1385581-1384757 (Counterclockwise)

Preceding gene: 119774274

Following gene: 119774272

Centisome position: 32.18

GC content: 54.55

Gene sequence:

>825_bases
ATGGAGGCTTTACGCCAGCGTATCGAGGCGGCTTTTGAAGCTCGCGCAAACATCACCCCAAGCAGTGTCGAGCCAGGCGT
GCGTGCCGATGTTGAGACAGTGATCAACATGCTCGACAAGGGCGAAATGCGCGTGGCCGAGAAAATTGACGGCCAGTGGC
ATGTTAACCAATGGCTGAAAAAGGCCGTACTGCTGTCGTTCCGCATTTTTGACAATGGCGTTATCGAAGGCGGCGAAACC
AAGTACTTCGATAAGGTACCCATGAAGTTTGCTGATTACGACGAAGCACGTTTCCGCGCCGAAGCCATCCGGGTTGTGCC
TCCTGCTGCCGTGCGTAAAGGCTCGTTTATCGGTAAAAACACCGTGCTGATGCCATCTTACGTGAACCTCGGGGCCTATG
TTGACGAAGGTACCATGGTTGACACCTGGGCGACCGTGGGCTCCTGTGCGCAAATTGGTAAAAACGTGCACCTGTCTGGT
GGCGTCGGCATCGGCGGCGTACTCGAACCGTTGCAGGCTGGCCCCACCATCATTGAAGACAACTGCTTCATCGGTGCCCG
CTCTGAAATCGTAGAAGGCGTGGTGGTAGAAGAAGGCTCTGTGATCTCCATGGGCGTTTACATTGGCCAGAGCACCCGCA
TTTACGACCGTGAAACCGGTGAAATCCATTACGGTCGCGTTCCGGCCGGCTCAGTAGTAGTATCAGGTACCCTGCCTTCG
TCATGCGGTAAGTACAACCTCTACGCCGCCATCATTGTGAAGAAGGTCGATGAAAAGACCCGCGGCAAAGTCGGTATCAA
TGAACTGCTGCGTATCGTCGATTAA

Upstream 100 bases:

>100_bases
AAGCCCTCAGTGACGAGGAACAGCGACGGCTTAAAGAGGCACTGGTCAGTGCCCTGTCCCAGACAATTTTTTAACACCTT
ATCAAAACGGGAGAACCCAC

Downstream 100 bases:

>100_bases
ATAGTACACAATATAAAAAAGCAGACTCAGGTCTGCTTTTTTATTGTCTGAACTTATCCACCGCAATGTAATGGCGGTGC
ATTACACCAATCAATTTTCA

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MEALRQRIEAAFEARANITPSSVEPGVRADVETVINMLDKGEMRVAEKIDGQWHVNQWLKKAVLLSFRIFDNGVIEGGET
KYFDKVPMKFADYDEARFRAEAIRVVPPAAVRKGSFIGKNTVLMPSYVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPLQAGPTIIEDNCFIGARSEIVEGVVVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVSGTLPS
SCGKYNLYAAIIVKKVDEKTRGKVGINELLRIVD

Sequences:

>Translated_274_residues
MEALRQRIEAAFEARANITPSSVEPGVRADVETVINMLDKGEMRVAEKIDGQWHVNQWLKKAVLLSFRIFDNGVIEGGET
KYFDKVPMKFADYDEARFRAEAIRVVPPAAVRKGSFIGKNTVLMPSYVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPLQAGPTIIEDNCFIGARSEIVEGVVVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVSGTLPS
SCGKYNLYAAIIVKKVDEKTRGKVGINELLRIVD
>Mature_274_residues
MEALRQRIEAAFEARANITPSSVEPGVRADVETVINMLDKGEMRVAEKIDGQWHVNQWLKKAVLLSFRIFDNGVIEGGET
KYFDKVPMKFADYDEARFRAEAIRVVPPAAVRKGSFIGKNTVLMPSYVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPLQAGPTIIEDNCFIGARSEIVEGVVVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVSGTLPS
SCGKYNLYAAIIVKKVDEKTRGKVGINELLRIVD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=274, Percent_Identity=80.6569343065693, Blast_Score=434, Evalue=1e-123,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_SHEAM (A1S4N7)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927013.1
- ProteinModelPortal:   A1S4N7
- SMR:   A1S4N7
- STRING:   A1S4N7
- GeneID:   4603388
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1136
- NMPDR:   fig|326297.7.peg.1068
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- PhylomeDB:   A1S4N7
- ProtClustDB:   PRK11830
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 29740; Mature: 29740

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 104-104 BINDING 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALRQRIEAAFEARANITPSSVEPGVRADVETVINMLDKGEMRVAEKIDGQWHVNQWLK
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCCHHHHHHH
KAVLLSFRIFDNGVIEGGETKYFDKVPMKFADYDEARFRAEAIRVVPPAAVRKGSFIGKN
HHHHHHHEEECCCEECCCCCCCHHCCCCCCCCCHHHHHHHHHEEECCCHHHHCCCCCCCC
TVLMPSYVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQAGPTIIED
EEECCCHHCCCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCCEEEC
NCFIGARSEIVEGVVVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVSGTLPS
CCEECCHHHHHCEEEECCCCEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEEECCCCC
SCGKYNLYAAIIVKKVDEKTRGKVGINELLRIVD
CCCCCEEEEEEEEEHHCHHHCCCCCHHHHHHHCC
>Mature Secondary Structure
MEALRQRIEAAFEARANITPSSVEPGVRADVETVINMLDKGEMRVAEKIDGQWHVNQWLK
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCCHHHHHHH
KAVLLSFRIFDNGVIEGGETKYFDKVPMKFADYDEARFRAEAIRVVPPAAVRKGSFIGKN
HHHHHHHEEECCCEECCCCCCCHHCCCCCCCCCHHHHHHHHHEEECCCHHHHCCCCCCCC
TVLMPSYVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQAGPTIIED
EEECCCHHCCCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCCEEEC
NCFIGARSEIVEGVVVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVSGTLPS
CCEECCHHHHHCEEEECCCCEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEEECCCCC
SCGKYNLYAAIIVKKVDEKTRGKVGINELLRIVD
CCCCCEEEEEEEEEHHCHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA