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The map label for this gene is ycgM [H]

Identifier: 119774230

GI number: 119774230

Start: 1319569

End: 1320177

Strand: Direct

Name: ycgM [H]

Synonym: Sama_1093

Alternate gene names: 119774230

Gene position: 1319569-1320177 (Clockwise)

Preceding gene: 119774229

Following gene: 119774231

Centisome position: 30.64

GC content: 57.47

Gene sequence:

>609_bases
ATGAAGCAGGTGTTTTTATCGGGCCGCGCGGTATCGCCGTCAAAGGTGGTCTGTATAGGCCGTAACTACGTGGCCCACGC
AGAAGAACTCGGCAACGAAGTGCCCTCCGAGCCTGTTGTTTTTGTTAAGCCTGCCAGCGCCATTGGCAATGTGCTGCACA
GCACCCAGGGCGAAGTGCTCCACTATGAGGCTGAAATTTGCTTTATGGTGGCCCGCGGCCAATTGGTCGCGGCCAGTGTG
GGCTTGGACTTAACCAAGAGAGCAACCCAAAACCGCCTCAAAGCCAAAGGCTTGCCGTGGGAGCGTGCCAAGGCCTTCGA
CGGCTCGGCGCTTTTTGGTGAGTTTGTCCCTTGCACAAGCAGTGAAGGGCTGAGCCTGGTGTTCAGTTGTGATGGCGTCA
TTTTACAGCAGGGTGGCTGCGAGCTGATGTTGTTTTCACCCGAGCAACTCCTTGAGGAGATCGGCTCATTTATGACACTG
GAAGATGGCGACATTTTGATGACGGGCACCCCCGCAGGTGTTGGCCCTTTACAGGCGGGCGGGCACTACCGCGCCGAACT
GCGCTGTGGCGATGAGCTGCTGACCAGTGTGAGTTGGACGGCCCACTGA

Upstream 100 bases:

>100_bases
TGAAGGGCTCTACCATATTGCCCAGTTTGCCGGTGACGAAATTGAAATCGTTAACGAGCAACTGGATGAATTTTTGATGG
AATACGCCTAAGGAGCGAAG

Downstream 100 bases:

>100_bases
GCTATATCCTTCAAGCTTTTAGCCTGACATGACTTGGGCAGCGCCCTAAAATACGTAATACTTTCGAATAGTGTATTCAG
TCGGAGCTGCCATGGTCAGG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKQVFLSGRAVSPSKVVCIGRNYVAHAEELGNEVPSEPVVFVKPASAIGNVLHSTQGEVLHYEAEICFMVARGQLVAASV
GLDLTKRATQNRLKAKGLPWERAKAFDGSALFGEFVPCTSSEGLSLVFSCDGVILQQGGCELMLFSPEQLLEEIGSFMTL
EDGDILMTGTPAGVGPLQAGGHYRAELRCGDELLTSVSWTAH

Sequences:

>Translated_202_residues
MKQVFLSGRAVSPSKVVCIGRNYVAHAEELGNEVPSEPVVFVKPASAIGNVLHSTQGEVLHYEAEICFMVARGQLVAASV
GLDLTKRATQNRLKAKGLPWERAKAFDGSALFGEFVPCTSSEGLSLVFSCDGVILQQGGCELMLFSPEQLLEEIGSFMTL
EDGDILMTGTPAGVGPLQAGGHYRAELRCGDELLTSVSWTAH
>Mature_202_residues
MKQVFLSGRAVSPSKVVCIGRNYVAHAEELGNEVPSEPVVFVKPASAIGNVLHSTQGEVLHYEAEICFMVARGQLVAASV
GLDLTKRATQNRLKAKGLPWERAKAFDGSALFGEFVPCTSSEGLSLVFSCDGVILQQGGCELMLFSPEQLLEEIGSFMTL
EDGDILMTGTPAGVGPLQAGGHYRAELRCGDELLTSVSWTAH

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI66348062, Length=213, Percent_Identity=35.2112676056338, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI215422413, Length=190, Percent_Identity=34.7368421052632, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI13654274, Length=190, Percent_Identity=34.7368421052632, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI156231349, Length=200, Percent_Identity=30.5, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI40786394, Length=200, Percent_Identity=29.5, Blast_Score=85, Evalue=5e-17,
Organism=Escherichia coli, GI1787428, Length=187, Percent_Identity=38.5026737967914, Blast_Score=126, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17557057, Length=185, Percent_Identity=35.1351351351351, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6324161, Length=235, Percent_Identity=30.6382978723404, Blast_Score=118, Evalue=8e-28,
Organism=Drosophila melanogaster, GI28571789, Length=198, Percent_Identity=29.2929292929293, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 21556; Mature: 21556

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVFLSGRAVSPSKVVCIGRNYVAHAEELGNEVPSEPVVFVKPASAIGNVLHSTQGEVL
CCEEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCCCCCEE
HYEAEICFMVARGQLVAASVGLDLTKRATQNRLKAKGLPWERAKAFDGSALFGEFVPCTS
EEEEEEEEEEECCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCHHCCCCCCCC
SEGLSLVFSCDGVILQQGGCELMLFSPEQLLEEIGSFMTLEDGDILMTGTPAGVGPLQAG
CCCCEEEEECCCEEEECCCCEEEEECHHHHHHHHHCEEEECCCCEEEECCCCCCCCCCCC
GHYRAELRCGDELLTSVSWTAH
CCEEEEEECCHHHHHHCCCCCC
>Mature Secondary Structure
MKQVFLSGRAVSPSKVVCIGRNYVAHAEELGNEVPSEPVVFVKPASAIGNVLHSTQGEVL
CCEEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCCCCCEE
HYEAEICFMVARGQLVAASVGLDLTKRATQNRLKAKGLPWERAKAFDGSALFGEFVPCTS
EEEEEEEEEEECCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCHHCCCCCCCC
SEGLSLVFSCDGVILQQGGCELMLFSPEQLLEEIGSFMTLEDGDILMTGTPAGVGPLQAG
CCCCEEEEECCCEEEECCCCEEEEECHHHHHHHHHCEEEECCCCEEEECCCCCCCCCCCC
GHYRAELRCGDELLTSVSWTAH
CCEEEEEECCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]