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The map label for this gene is gpo [H]

Identifier: 119774217

GI number: 119774217

Start: 1307678

End: 1308172

Strand: Reverse

Name: gpo [H]

Synonym: Sama_1080

Alternate gene names: 119774217

Gene position: 1308172-1307678 (Counterclockwise)

Preceding gene: 119774220

Following gene: 119774214

Centisome position: 30.38

GC content: 52.32

Gene sequence:

>495_bases
ATGACGGATCTGTATCAATTTGCCGCCACCACCATCAAGGGCGAGCAGCAGCCATTGGCCAACTATCGCGGTAAGGTCTT
ATTGATAGTCAATACCGCCAGCAAATGTGGCTTTACCCCGCAATATCAAGGGCTGGAAAGCCTCTATCGCAAATACCATG
ACCAAGGCCTCGAAATACTCGGCTTTCCCTGCAACCAGTTTGGCGCCCAGGAGCAAGGGAGTGAGTCAGACATTCAGAGT
TTCTGTGAACTCAATTTTGGTGTGACCTTTCCGCTGTTTGCCAAGGTTGATGTCAATGGCGAGCAGGCCCACCCGCTGTT
TACTCACCTTAAGCAGGAAGCACCGGGCCTCCTTGGCAGTAAGGCCATCAAATGGAACTTCACCAAGTTTTTGGTCGGCC
GTGACGGCAAGGTGAGAGACAGGTTCGCCCCCACTACCGATCCCCAAAAGCTGGAAAAGGATATCGAGGCACTGCTGAAC
GAAGCGGCGAAATAA

Upstream 100 bases:

>100_bases
TGTCATATCAACCGAGCAATTATATTGCACACAATTTAATTGCTCACATAGAAAAATGCATTTAGAATGTCTTTGTTCAT
TTTCTACCCGGAGTATTTTT

Downstream 100 bases:

>100_bases
ACAATTTGGGATCAGGGAGATAGTAAAAATTCAGCCATTTTCGCTATTTTTTGAGCCGTGTCGTGGAACTTTTTACCGAA
CGCACGACTCAAACATAGTG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTDLYQFAATTIKGEQQPLANYRGKVLLIVNTASKCGFTPQYQGLESLYRKYHDQGLEILGFPCNQFGAQEQGSESDIQS
FCELNFGVTFPLFAKVDVNGEQAHPLFTHLKQEAPGLLGSKAIKWNFTKFLVGRDGKVRDRFAPTTDPQKLEKDIEALLN
EAAK

Sequences:

>Translated_164_residues
MTDLYQFAATTIKGEQQPLANYRGKVLLIVNTASKCGFTPQYQGLESLYRKYHDQGLEILGFPCNQFGAQEQGSESDIQS
FCELNFGVTFPLFAKVDVNGEQAHPLFTHLKQEAPGLLGSKAIKWNFTKFLVGRDGKVRDRFAPTTDPQKLEKDIEALLN
EAAK
>Mature_163_residues
TDLYQFAATTIKGEQQPLANYRGKVLLIVNTASKCGFTPQYQGLESLYRKYHDQGLEILGFPCNQFGAQEQGSESDIQSF
CELNFGVTFPLFAKVDVNGEQAHPLFTHLKQEAPGLLGSKAIKWNFTKFLVGRDGKVRDRFAPTTDPQKLEKDIEALLNE
AAK

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=160, Percent_Identity=42.5, Blast_Score=132, Evalue=1e-31,
Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=43.8709677419355, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=43.8709677419355, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI192455698, Length=163, Percent_Identity=34.9693251533742, Blast_Score=111, Evalue=3e-25,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=45.0381679389313, Blast_Score=107, Evalue=5e-24,
Organism=Homo sapiens, GI6006001, Length=180, Percent_Identity=39.4444444444444, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI41406084, Length=185, Percent_Identity=36.7567567567568, Blast_Score=100, Evalue=4e-22,
Organism=Homo sapiens, GI4557629, Length=178, Percent_Identity=36.5168539325843, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI33186887, Length=153, Percent_Identity=39.8692810457516, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI32967607, Length=183, Percent_Identity=31.1475409836066, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788003, Length=157, Percent_Identity=46.4968152866242, Blast_Score=151, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17506887, Length=162, Percent_Identity=51.2345679012346, Blast_Score=164, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=51.875, Blast_Score=162, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI193210707, Length=163, Percent_Identity=47.239263803681, Blast_Score=137, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=39.2405063291139, Blast_Score=123, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17550320, Length=184, Percent_Identity=34.2391304347826, Blast_Score=108, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI193209493, Length=184, Percent_Identity=33.1521739130435, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17507603, Length=107, Percent_Identity=42.0560747663551, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71999642, Length=75, Percent_Identity=42.6666666666667, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71993573, Length=94, Percent_Identity=36.1702127659575, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193210709, Length=71, Percent_Identity=46.4788732394366, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322228, Length=162, Percent_Identity=52.4691358024691, Blast_Score=189, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=54.375, Blast_Score=187, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6322826, Length=161, Percent_Identity=47.2049689440994, Blast_Score=155, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24656767, Length=162, Percent_Identity=48.1481481481481, Blast_Score=143, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=48.4276729559748, Blast_Score=143, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=48.4276729559748, Blast_Score=143, Evalue=4e-35,
Organism=Drosophila melanogaster, GI85726443, Length=148, Percent_Identity=47.2972972972973, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18334; Mature: 18203

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLYQFAATTIKGEQQPLANYRGKVLLIVNTASKCGFTPQYQGLESLYRKYHDQGLEIL
CCHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCEEE
GFPCNQFGAQEQGSESDIQSFCELNFGVTFPLFAKVDVNGEQAHPLFTHLKQEAPGLLGS
ECCCHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCC
KAIKWNFTKFLVGRDGKVRDRFAPTTDPQKLEKDIEALLNEAAK
CEEEEEHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDLYQFAATTIKGEQQPLANYRGKVLLIVNTASKCGFTPQYQGLESLYRKYHDQGLEIL
CHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCEEE
GFPCNQFGAQEQGSESDIQSFCELNFGVTFPLFAKVDVNGEQAHPLFTHLKQEAPGLLGS
ECCCHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCC
KAIKWNFTKFLVGRDGKVRDRFAPTTDPQKLEKDIEALLNEAAK
CEEEEEHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]