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The map label for this gene is nrdR

Identifier: 119774152

GI number: 119774152

Start: 1230372

End: 1230821

Strand: Direct

Name: nrdR

Synonym: Sama_1015

Alternate gene names: 119774152

Gene position: 1230372-1230821 (Clockwise)

Preceding gene: 119774151

Following gene: 119774153

Centisome position: 28.57

GC content: 54.22

Gene sequence:

>450_bases
ATGCACTGTCCATTTTGCAACGCAACCGACACCAAGGTGATCGACTCCCGTCTGGTGGGAGAAGGGCATCAGGTAAGGCG
TCGGCGGGAGTGCACTGAATGCCACGAGCGCTTTACTACCTTTGAAGGTGCCGAACTGGTGATGCCGAGGGTCATCAAGC
GTGATGGCACCCGTCAGCCATTCGATGAAGAAAAGCTGCGCAGCGGTATGCTCAAAGCCGTGGAAAAACGCCCCGTGTCC
ATCGATCAGATTGACCAGGCGATGAACAAGATTAAGTCAACTTTGCGTGCCACCGGCGAGCGCGAAGTGCCCTCAGAGAT
GGTTGGCAACCTGATGATGGACAGCCTGATTGAGCTGGATAAGGTCGCTTATATCCGCTTTGCCTCCGTATACCGCGCCT
TTGAAGATGTTTCTGAGTTTGGAGAGGCCATTGCCAGGCTTCAGAAGTAA

Upstream 100 bases:

>100_bases
TTTAACCTGAATAGGATACACTCATGGCCGCTGCGATAGCGGCCATTTTTATTTGTATTGCGGTTCAATTTGTCCTTCAT
TCAGCACGCCAGGAGGCCCC

Downstream 100 bases:

>100_bases
GCACTGCGGCGGACTGTATCCATGAGTAATAACAGCGTTTTTTCCGCTCTTGACCGCGCCATGATGGCCCGCGCCATCAT
GCTGGCCAAGCGTGGCCAGT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MHCPFCNATDTKVIDSRLVGEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGTRQPFDEEKLRSGMLKAVEKRPVS
IDQIDQAMNKIKSTLRATGEREVPSEMVGNLMMDSLIELDKVAYIRFASVYRAFEDVSEFGEAIARLQK

Sequences:

>Translated_149_residues
MHCPFCNATDTKVIDSRLVGEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGTRQPFDEEKLRSGMLKAVEKRPVS
IDQIDQAMNKIKSTLRATGEREVPSEMVGNLMMDSLIELDKVAYIRFASVYRAFEDVSEFGEAIARLQK
>Mature_149_residues
MHCPFCNATDTKVIDSRLVGEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGTRQPFDEEKLRSGMLKAVEKRPVS
IDQIDQAMNKIKSTLRATGEREVPSEMVGNLMMDSLIELDKVAYIRFASVYRAFEDVSEFGEAIARLQK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=74.3243243243243, Blast_Score=234, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_SHEAM (A1S4B6)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926892.1
- STRING:   A1S4B6
- GeneID:   4603267
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1015
- NMPDR:   fig|326297.7.peg.955
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   A1S4B6
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17126; Mature: 17126

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCNATDTKVIDSRLVGEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGTRQP
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
FDEEKLRSGMLKAVEKRPVSIDQIDQAMNKIKSTLRATGEREVPSEMVGNLMMDSLIELD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KVAYIRFASVYRAFEDVSEFGEAIARLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHCPFCNATDTKVIDSRLVGEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGTRQP
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
FDEEKLRSGMLKAVEKRPVSIDQIDQAMNKIKSTLRATGEREVPSEMVGNLMMDSLIELD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KVAYIRFASVYRAFEDVSEFGEAIARLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA