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The map label for this gene is ribD [H]

Identifier: 119774153

GI number: 119774153

Start: 1230843

End: 1231979

Strand: Direct

Name: ribD [H]

Synonym: Sama_1016

Alternate gene names: 119774153

Gene position: 1230843-1231979 (Clockwise)

Preceding gene: 119774152

Following gene: 119774154

Centisome position: 28.58

GC content: 59.01

Gene sequence:

>1137_bases
ATGAGTAATAACAGCGTTTTTTCCGCTCTTGACCGCGCCATGATGGCCCGCGCCATCATGCTGGCCAAGCGTGGCCAGTA
CACCACCCGACCCAATCCCAATGTGGGCTGTGTGATAGTTAATGACGCCGGTGACATCGTTGGCGAAGGATGGCATATCC
GCGCAGGCGGCCCCCATGCCGAAGTGCATGCCCTCAAGGCTGCCGCAGACAAGGCCCGGGGCGCCACTGCCTATGTCACT
CTTGAGCCCTGCAGTCACTATGGACGCACACCGCCCTGCGCCAAGGCGCTGATTGACAATGGCTTAAAGCGTGTCGTGGT
GGCCATGACCGACCCCAACCCCCAGGTGGCGGGCAGGGGGATTAAGCTGCTTCAGGATGCTGGCATCGAAGTGGCTCACG
GCCTGATGGAAGCCGAGGCGCGCGCACTGAACCCGGGCTTTTTGTCGCGGATGGAGCGTAAACGCCCGTTTGTGACCGTC
AAAGTAGGGGCGAGTCTCGACGGAAAAACCGCACTGTCCAGTGGTGAGTCCAAGTGGATAACAGGTCCCGAGGCGCGCCG
CGACGTGCAAAGGCTTCGGGCCAAATCCTGCGCCCTGATTACCGGTATCGATACTGTGCTGTTGGATGACCCCAGCCTCA
ATGTTCGCCACGGTGAACTTGGCAGTCTGGGAGCAAGCCTGACGGAGCCCGAGCTTATCCAACCCATTCGGGTTGTGCTA
GACAGTCAGCGGCGTATGAGCACTGATGCCAAACTCTTTGGTATCACTGGCCCGATACTGCTGGTGTCTGCAGAGCCATA
TGATGAGAAATTTTTGCACTCGCTGCCGGACTTTGTTACCTGTTTGATCCTGCCCGGTTCCCATGGCCGTATCGACCTTG
CCGCACTGCTTAGCCACCTCGGTGAAAACTGCAACCGGGTGCTGGTTGAAGCCGGCGGAACCCTCGCCGGCGCCTTTATC
GCCGCGGGACTTTGTGATGAGCTGGTGCTGTATCAGGCGCCAAAACTCCTTGGCAGCCATGGCCGCGATATGCTGCAACT
GCCCGACTATCAGACCATGGCCGAGGTGCCGGGTCTTAAGCTTATTGATGAGCGTAAAGTGGGCCAGGATTGGCGCTTTA
CCTTCACTGTGGCCTGA

Upstream 100 bases:

>100_bases
TATCCGCTTTGCCTCCGTATACCGCGCCTTTGAAGATGTTTCTGAGTTTGGAGAGGCCATTGCCAGGCTTCAGAAGTAAG
CACTGCGGCGGACTGTATCC

Downstream 100 bases:

>100_bases
GTGTCAGCATCTGCTGCATCGAGCCTAAAGAGGATTTATGTTTACCGGGATCATTGAAGCCGTTGGCCAGTTAAGACGAA
TCGATCGTAAGGGCGATGAT

Product: diaminohydroxyphosphoribosylaminopyrimidine deaminase., 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MSNNSVFSALDRAMMARAIMLAKRGQYTTRPNPNVGCVIVNDAGDIVGEGWHIRAGGPHAEVHALKAAADKARGATAYVT
LEPCSHYGRTPPCAKALIDNGLKRVVVAMTDPNPQVAGRGIKLLQDAGIEVAHGLMEAEARALNPGFLSRMERKRPFVTV
KVGASLDGKTALSSGESKWITGPEARRDVQRLRAKSCALITGIDTVLLDDPSLNVRHGELGSLGASLTEPELIQPIRVVL
DSQRRMSTDAKLFGITGPILLVSAEPYDEKFLHSLPDFVTCLILPGSHGRIDLAALLSHLGENCNRVLVEAGGTLAGAFI
AAGLCDELVLYQAPKLLGSHGRDMLQLPDYQTMAEVPGLKLIDERKVGQDWRFTFTVA

Sequences:

>Translated_378_residues
MSNNSVFSALDRAMMARAIMLAKRGQYTTRPNPNVGCVIVNDAGDIVGEGWHIRAGGPHAEVHALKAAADKARGATAYVT
LEPCSHYGRTPPCAKALIDNGLKRVVVAMTDPNPQVAGRGIKLLQDAGIEVAHGLMEAEARALNPGFLSRMERKRPFVTV
KVGASLDGKTALSSGESKWITGPEARRDVQRLRAKSCALITGIDTVLLDDPSLNVRHGELGSLGASLTEPELIQPIRVVL
DSQRRMSTDAKLFGITGPILLVSAEPYDEKFLHSLPDFVTCLILPGSHGRIDLAALLSHLGENCNRVLVEAGGTLAGAFI
AAGLCDELVLYQAPKLLGSHGRDMLQLPDYQTMAEVPGLKLIDERKVGQDWRFTFTVA
>Mature_377_residues
SNNSVFSALDRAMMARAIMLAKRGQYTTRPNPNVGCVIVNDAGDIVGEGWHIRAGGPHAEVHALKAAADKARGATAYVTL
EPCSHYGRTPPCAKALIDNGLKRVVVAMTDPNPQVAGRGIKLLQDAGIEVAHGLMEAEARALNPGFLSRMERKRPFVTVK
VGASLDGKTALSSGESKWITGPEARRDVQRLRAKSCALITGIDTVLLDDPSLNVRHGELGSLGASLTEPELIQPIRVVLD
SQRRMSTDAKLFGITGPILLVSAEPYDEKFLHSLPDFVTCLILPGSHGRIDLAALLSHLGENCNRVLVEAGGTLAGAFIA
AGLCDELVLYQAPKLLGSHGRDMLQLPDYQTMAEVPGLKLIDERKVGQDWRFTFTVA

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=362, Percent_Identity=54.1436464088398, Blast_Score=377, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40565; Mature: 40434

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNSVFSALDRAMMARAIMLAKRGQYTTRPNPNVGCVIVNDAGDIVGEGWHIRAGGPHA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCH
EVHALKAAADKARGATAYVTLEPCSHYGRTPPCAKALIDNGLKRVVVAMTDPNPQVAGRG
HHHHHHHHHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCC
IKLLQDAGIEVAHGLMEAEARALNPGFLSRMERKRPFVTVKVGASLDGKTALSSGESKWI
HHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCCC
TGPEARRDVQRLRAKSCALITGIDTVLLDDPSLNVRHGELGSLGASLTEPELIQPIRVVL
CCHHHHHHHHHHHHHHCEEEECCCEEEECCCCCCEECCCCCCCCCCCCCCHHHHHHHHHH
DSQRRMSTDAKLFGITGPILLVSAEPYDEKFLHSLPDFVTCLILPGSHGRIDLAALLSHL
CCHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHCHHHEEEEEECCCCCCEEHHHHHHHH
GENCNRVLVEAGGTLAGAFIAAGLCDELVLYQAPKLLGSHGRDMLQLPDYQTMAEVPGLK
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEECCCHHHHHHCCCCE
LIDERKVGQDWRFTFTVA
EECCCCCCCCEEEEEEEC
>Mature Secondary Structure 
SNNSVFSALDRAMMARAIMLAKRGQYTTRPNPNVGCVIVNDAGDIVGEGWHIRAGGPHA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCH
EVHALKAAADKARGATAYVTLEPCSHYGRTPPCAKALIDNGLKRVVVAMTDPNPQVAGRG
HHHHHHHHHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCC
IKLLQDAGIEVAHGLMEAEARALNPGFLSRMERKRPFVTVKVGASLDGKTALSSGESKWI
HHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCCC
TGPEARRDVQRLRAKSCALITGIDTVLLDDPSLNVRHGELGSLGASLTEPELIQPIRVVL
CCHHHHHHHHHHHHHHCEEEECCCEEEECCCCCCEECCCCCCCCCCCCCCHHHHHHHHHH
DSQRRMSTDAKLFGITGPILLVSAEPYDEKFLHSLPDFVTCLILPGSHGRIDLAALLSHL
CCHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHCHHHEEEEEECCCCCCEEHHHHHHHH
GENCNRVLVEAGGTLAGAFIAAGLCDELVLYQAPKLLGSHGRDMLQLPDYQTMAEVPGLK
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEECCCHHHHHHCCCCE
LIDERKVGQDWRFTFTVA
EECCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]