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The map label for this gene is nagA [H]

Identifier: 119774083

GI number: 119774083

Start: 1145587

End: 1146720

Strand: Direct

Name: nagA [H]

Synonym: Sama_0946

Alternate gene names: 119774083

Gene position: 1145587-1146720 (Clockwise)

Preceding gene: 119774082

Following gene: 119774084

Centisome position: 26.6

GC content: 58.47

Gene sequence:

>1134_bases
ATGAAAACGACCCTTATCGCCGAGCGCCTGTTTGATGGCGAGCAGTTTCACCACAATGTGCCTTTGACTGTGGAAGACGG
CCAGGTGTTGGCCCTCGATACTGTCGCCGGCTGCGCCGAGGTAAGATTGCAGGGCACCCTGGTGCCCGGTTTTATCGATG
TGCAGGTTAATGGTGGTGGCGGTGTGCTTTTTAACGACACCCCAACCGTGGCTGCCATTGAGGCCATTGGGGCGGCGCAT
GCCCGCTTTGGCACCACAGGTTATTTGCCGACGCTCATCACCGATAAGGTAGAGACCATGGCCCGGGCCGCCGATGCGGC
CGCAGAGGCTATCGCCAAAGGATCCACCGGGGTGCTCGGGGTTCACTTTGAGGGGCCGCATTTGTCGGTACCCAAAAAAG
GCGTGCATCCCGAGTCGCACATTCGCCGTATCGGCGATCGCGAACTGGAGATTTTTGCCCGTCAGGATTTGGGGCTAAAG
GTAGTGACCCTGGCGCCTGAGAATGTGTCTCCTGAGGTGATCTGCGCTCTGGTCGATGTGGGAGTCAAGGTCTGCTTGGG
CCACTCCAATGCTGATTACGCGACCACTGTCGCGGCGCTGGAAGCCGGTGCCACCGGTTTTACCCACCTTTATAACGCCA
TGTCGGCGCTCACTTCCCGAGAGCCAGGCGTTGTCGGCGCTGCCATCGACAGTGATGAAGCCTGGTGCGGTTTGATTGTT
GACGGTCACCACGTGCATTCGGCGGCGGCCCGTATTGCTATCAAGGCCAAGCCCCGCGGCAAGGTGATGTTGGTGACCGA
TGCCATGCCTCCGGTTGGCATGGATGATAACGCCAGCTTTGAACTCTTTGGTATTCAAGTGGTACGTCAGGGGGACAAGC
TTAATGCCCTGACCGGAGAGCTTGCCGGCTGCGTGTTGGACATGGCTGGTGCAGTGCAAAATACAGTCGACATGCTGGGA
CTGCCTCAGGCCGAAGCCATTCGCATGGCATCACTTTATCCTGCCGCCTTCCTTGGTATCGACAACAGGGTGGGAACCCT
GAGTGTCGGTAAGCAAGCCGATATGGTACTGCTCGATGATAACGGCCGTTGCCGCGGAACCTGGATTGGCGGTAGGCAGG
TGTTTGGCCTGTGA

Upstream 100 bases:

>100_bases
GATGTGGCCGCCGTAGCCGTTGCCCGTGGCATCGACCCGGATGCACCGGCGGGCCTGAAAAAGGTTACCCAGACCCTGTA
ATTGATTGCCCGGAGCGTCC

Downstream 100 bases:

>100_bases
CCCACACTAGACGACTACCGGCCCTGGTGGAGTCAGCTCCTCCGGGGCCTGTTTTTATCTGTAAAAAACTGAAAGACTGA
ACAGATAACAAAAATAAAGG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MKTTLIAERLFDGEQFHHNVPLTVEDGQVLALDTVAGCAEVRLQGTLVPGFIDVQVNGGGGVLFNDTPTVAAIEAIGAAH
ARFGTTGYLPTLITDKVETMARAADAAAEAIAKGSTGVLGVHFEGPHLSVPKKGVHPESHIRRIGDRELEIFARQDLGLK
VVTLAPENVSPEVICALVDVGVKVCLGHSNADYATTVAALEAGATGFTHLYNAMSALTSREPGVVGAAIDSDEAWCGLIV
DGHHVHSAAARIAIKAKPRGKVMLVTDAMPPVGMDDNASFELFGIQVVRQGDKLNALTGELAGCVLDMAGAVQNTVDMLG
LPQAEAIRMASLYPAAFLGIDNRVGTLSVGKQADMVLLDDNGRCRGTWIGGRQVFGL

Sequences:

>Translated_377_residues
MKTTLIAERLFDGEQFHHNVPLTVEDGQVLALDTVAGCAEVRLQGTLVPGFIDVQVNGGGGVLFNDTPTVAAIEAIGAAH
ARFGTTGYLPTLITDKVETMARAADAAAEAIAKGSTGVLGVHFEGPHLSVPKKGVHPESHIRRIGDRELEIFARQDLGLK
VVTLAPENVSPEVICALVDVGVKVCLGHSNADYATTVAALEAGATGFTHLYNAMSALTSREPGVVGAAIDSDEAWCGLIV
DGHHVHSAAARIAIKAKPRGKVMLVTDAMPPVGMDDNASFELFGIQVVRQGDKLNALTGELAGCVLDMAGAVQNTVDMLG
LPQAEAIRMASLYPAAFLGIDNRVGTLSVGKQADMVLLDDNGRCRGTWIGGRQVFGL
>Mature_377_residues
MKTTLIAERLFDGEQFHHNVPLTVEDGQVLALDTVAGCAEVRLQGTLVPGFIDVQVNGGGGVLFNDTPTVAAIEAIGAAH
ARFGTTGYLPTLITDKVETMARAADAAAEAIAKGSTGVLGVHFEGPHLSVPKKGVHPESHIRRIGDRELEIFARQDLGLK
VVTLAPENVSPEVICALVDVGVKVCLGHSNADYATTVAALEAGATGFTHLYNAMSALTSREPGVVGAAIDSDEAWCGLIV
DGHHVHSAAARIAIKAKPRGKVMLVTDAMPPVGMDDNASFELFGIQVVRQGDKLNALTGELAGCVLDMAGAVQNTVDMLG
LPQAEAIRMASLYPAAFLGIDNRVGTLSVGKQADMVLLDDNGRCRGTWIGGRQVFGL

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=382, Percent_Identity=35.3403141361257, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI224922791, Length=378, Percent_Identity=35.4497354497354, Blast_Score=172, Evalue=4e-43,
Organism=Escherichia coli, GI1786892, Length=374, Percent_Identity=37.7005347593583, Blast_Score=222, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17553768, Length=353, Percent_Identity=33.4277620396601, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI19920392, Length=337, Percent_Identity=37.9821958456973, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI281361140, Length=349, Percent_Identity=36.3896848137536, Blast_Score=184, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39400; Mature: 39400

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTLIAERLFDGEQFHHNVPLTVEDGQVLALDTVAGCAEVRLQGTLVPGFIDVQVNGGG
CCCHHHHHHHCCCCHHCCCCCEEECCCCEEEEECCCCCEEEEEEEEECCCEEEEEEECCC
GVLFNDTPTVAAIEAIGAAHARFGTTGYLPTLITDKVETMARAADAAAEAIAKGSTGVLG
EEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VHFEGPHLSVPKKGVHPESHIRRIGDRELEIFARQDLGLKVVTLAPENVSPEVICALVDV
EEECCCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHC
GVKVCLGHSNADYATTVAALEAGATGFTHLYNAMSALTSREPGVVGAAIDSDEAWCGLIV
CEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEE
DGHHVHSAAARIAIKAKPRGKVMLVTDAMPPVGMDDNASFELFGIQVVRQGDKLNALTGE
ECCCHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHH
LAGCVLDMAGAVQNTVDMLGLPQAEAIRMASLYPAAFLGIDNRVGTLSVGKQADMVLLDD
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCEEEECC
NGRCRGTWIGGRQVFGL
CCEEEEEEECCEEECCC
>Mature Secondary Structure
MKTTLIAERLFDGEQFHHNVPLTVEDGQVLALDTVAGCAEVRLQGTLVPGFIDVQVNGGG
CCCHHHHHHHCCCCHHCCCCCEEECCCCEEEEECCCCCEEEEEEEEECCCEEEEEEECCC
GVLFNDTPTVAAIEAIGAAHARFGTTGYLPTLITDKVETMARAADAAAEAIAKGSTGVLG
EEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VHFEGPHLSVPKKGVHPESHIRRIGDRELEIFARQDLGLKVVTLAPENVSPEVICALVDV
EEECCCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHC
GVKVCLGHSNADYATTVAALEAGATGFTHLYNAMSALTSREPGVVGAAIDSDEAWCGLIV
CEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEE
DGHHVHSAAARIAIKAKPRGKVMLVTDAMPPVGMDDNASFELFGIQVVRQGDKLNALTGE
ECCCHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHH
LAGCVLDMAGAVQNTVDMLGLPQAEAIRMASLYPAAFLGIDNRVGTLSVGKQADMVLLDD
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCEEEECC
NGRCRGTWIGGRQVFGL
CCEEEEEEECCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]