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The map label for this gene is era [H]

Identifier: 119774018

GI number: 119774018

Start: 1070470

End: 1071468

Strand: Direct

Name: era [H]

Synonym: Sama_0881

Alternate gene names: 119774018

Gene position: 1070470-1071468 (Clockwise)

Preceding gene: 119774017

Following gene: 119774019

Centisome position: 24.86

GC content: 52.25

Gene sequence:

>999_bases
ATGAGCAAGAAACCCGCACCAGGCGTACCGGAAAACGAACCAAGCCTGGAAGATTTGCTGGCACAGATGAACAGCCAGAA
TCAACCCGAAGAGCACTACGATGTGACCTATTGTGGCATGGTAGCCATCGTTGGTCGTCCCAACGTAGGTAAATCCACCT
TGCTCAACAAGTTGCTGAAGCAAAAAATCAGTATTACTTCCCGTAAGCCCCAGACCACCCGTCACCGCATTATGGGTATT
CATACCGAAGGACCGAATCAAATCGTCTTTATTGATACCCCTGGTCTGCACATTGAAGAAAAGCGTGCCATCAACCGCCT
GATGAACCGTGCTGCTGCCAGCTCCCTGGCCGATGTGTCCATGGTCATCTTTGTCGTGGACGGCATGGAATGGACTGCCG
ACGATGAAATGGTGCTGAACAAGCTGCGCCGCGGCGGTGAGCATCGCAAGACAGTGCTGGCCATCAACAAGGTTGATGGC
ATCAAGGAAAAAGAAGATCTGTTCCCATACCTTATCGAAGTATCCAAGAAATACCCCTTCGATGACATAGTGCCAGTGTC
GGCCAAACAGGGCTCTAATGTAGAGCGGCTGCTGGATTTGGCCCGTGAATCGCTGCCCGAGTCTGTGTTCTTCTTCCCCG
AAGACTATGTTACCGACCGCAGCCAGCGCTTTATGGCCTCTGAGATTGTCCGTGAAAAGCTGATGCGCTTCCTCGGCGAT
GAACTGCCTTACGATGCCACGGTGGAAATCGAACAGTTCAAGATGATGGAAAACGGTGTTTACCAAATCAATGCCCTGGT
ACTGGTTGAGCGCGATGGCCAGAAACGTATGGTCATTGGTAAAAAAGGCGAGCGTATTCGCACCATTGCCACCGAGGCCC
GCAAAGACATGGAGCGCCTGTTCGATAACAAGGTATTCCTTGAGGTTTGGGTGAAGGTGAAATCCGGCTGGGCCGACGAC
GAGCGGGCCCTTCGCAGTCTGGGTTACGGCGAAGATTAA

Upstream 100 bases:

>100_bases
GCCGGGTGACCGACCTTGCCGATGCCGTCGTGGGTGTTGGCAGTTCTCGCCGTAAAGCCGAACAAATGGCGGCGGCACAA
GTTTTGGAATTATTGAATCA

Downstream 100 bases:

>100_bases
TCCCGGGGCCGCGATGGAAAGGGGTTACCTGCTGCATTCGCGTCCCTATCGGGAAAACAGCGCCATCGTAAACCTCTTGG
TGGATGGCGCAGGTCGGGTC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSKKPAPGVPENEPSLEDLLAQMNSQNQPEEHYDVTYCGMVAIVGRPNVGKSTLLNKLLKQKISITSRKPQTTRHRIMGI
HTEGPNQIVFIDTPGLHIEEKRAINRLMNRAAASSLADVSMVIFVVDGMEWTADDEMVLNKLRRGGEHRKTVLAINKVDG
IKEKEDLFPYLIEVSKKYPFDDIVPVSAKQGSNVERLLDLARESLPESVFFFPEDYVTDRSQRFMASEIVREKLMRFLGD
ELPYDATVEIEQFKMMENGVYQINALVLVERDGQKRMVIGKKGERIRTIATEARKDMERLFDNKVFLEVWVKVKSGWADD
ERALRSLGYGED

Sequences:

>Translated_332_residues
MSKKPAPGVPENEPSLEDLLAQMNSQNQPEEHYDVTYCGMVAIVGRPNVGKSTLLNKLLKQKISITSRKPQTTRHRIMGI
HTEGPNQIVFIDTPGLHIEEKRAINRLMNRAAASSLADVSMVIFVVDGMEWTADDEMVLNKLRRGGEHRKTVLAINKVDG
IKEKEDLFPYLIEVSKKYPFDDIVPVSAKQGSNVERLLDLARESLPESVFFFPEDYVTDRSQRFMASEIVREKLMRFLGD
ELPYDATVEIEQFKMMENGVYQINALVLVERDGQKRMVIGKKGERIRTIATEARKDMERLFDNKVFLEVWVKVKSGWADD
ERALRSLGYGED
>Mature_331_residues
SKKPAPGVPENEPSLEDLLAQMNSQNQPEEHYDVTYCGMVAIVGRPNVGKSTLLNKLLKQKISITSRKPQTTRHRIMGIH
TEGPNQIVFIDTPGLHIEEKRAINRLMNRAAASSLADVSMVIFVVDGMEWTADDEMVLNKLRRGGEHRKTVLAINKVDGI
KEKEDLFPYLIEVSKKYPFDDIVPVSAKQGSNVERLLDLARESLPESVFFFPEDYVTDRSQRFMASEIVREKLMRFLGDE
LPYDATVEIEQFKMMENGVYQINALVLVERDGQKRMVIGKKGERIRTIATEARKDMERLFDNKVFLEVWVKVKSGWADDE
RALRSLGYGED

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=322, Percent_Identity=25.4658385093168, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1788919, Length=299, Percent_Identity=67.5585284280936, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI87082120, Length=173, Percent_Identity=31.2138728323699, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532761, Length=192, Percent_Identity=29.1666666666667, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646434, Length=304, Percent_Identity=27.3026315789474, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 37905; Mature: 37774

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKPAPGVPENEPSLEDLLAQMNSQNQPEEHYDVTYCGMVAIVGRPNVGKSTLLNKLLK
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCCCEEEHEEEEECCCCCCHHHHHHHHHH
QKISITSRKPQTTRHRIMGIHTEGPNQIVFIDTPGLHIEEKRAINRLMNRAAASSLADVS
HHHHHCCCCCCCCHHHEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHE
MVIFVVDGMEWTADDEMVLNKLRRGGEHRKTVLAINKVDGIKEKEDLFPYLIEVSKKYPF
EEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
DDIVPVSAKQGSNVERLLDLARESLPESVFFFPEDYVTDRSQRFMASEIVREKLMRFLGD
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCHHHHCCHHHHHHHHHHHHHHHHHHHCC
ELPYDATVEIEQFKMMENGVYQINALVLVERDGQKRMVIGKKGERIRTIATEARKDMERL
CCCCCCEEHHHHHHHHHCCCEEEEEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHH
FDNKVFLEVWVKVKSGWADDERALRSLGYGED
HCCCEEEHHEEHHHCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
SKKPAPGVPENEPSLEDLLAQMNSQNQPEEHYDVTYCGMVAIVGRPNVGKSTLLNKLLK
CCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCCCEEEHEEEEECCCCCCHHHHHHHHHH
QKISITSRKPQTTRHRIMGIHTEGPNQIVFIDTPGLHIEEKRAINRLMNRAAASSLADVS
HHHHHCCCCCCCCHHHEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHE
MVIFVVDGMEWTADDEMVLNKLRRGGEHRKTVLAINKVDGIKEKEDLFPYLIEVSKKYPF
EEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
DDIVPVSAKQGSNVERLLDLARESLPESVFFFPEDYVTDRSQRFMASEIVREKLMRFLGD
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCHHHHCCHHHHHHHHHHHHHHHHHHHCC
ELPYDATVEIEQFKMMENGVYQINALVLVERDGQKRMVIGKKGERIRTIATEARKDMERL
CCCCCCEEHHHHHHHHHCCCEEEEEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHH
FDNKVFLEVWVKVKSGWADDERALRSLGYGED
HCCCEEEHHEEHHHCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA