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The map label for this gene is mdtA [H]

Identifier: 119773811

GI number: 119773811

Start: 829291

End: 830355

Strand: Direct

Name: mdtA [H]

Synonym: Sama_0673

Alternate gene names: 119773811

Gene position: 829291-830355 (Clockwise)

Preceding gene: 119773810

Following gene: 119773812

Centisome position: 19.26

GC content: 55.96

Gene sequence:

>1065_bases
ATGAGCAAGCTCAGGCCGTTTTCAGGGATAGGTATTGCCGCAGTGCTGGGGGGCTTTTTGCTCTCCTCAGCCACGCAGGG
CATTGCTGGTGAGGCCCCCAGGCCGGTTAAGGTCAGCCAGATAGCCCTGGCCGATAATATGAATCAAAGATTGCTACCGG
CAGAAGTCAGGGCATCTGAGCGCGCAGGGCTTTCATTTCGGGTCAGCGGCGAAATCATGGACATTTTGGTGCGCCCCGGC
GAAGAGGTCAAAGCCGGACAGTTACTGGCTAAGCTTGACCCGGCACTCTACGAGCAGCAGCTGGCAGTGGCCAAAGCCCA
GTATGCACTCGCCAAGGTACTCTATGAGCGTAACCTCAGCTTGGTGGAACAAGGGGTGGTGTCGCGCAACGATTTTGACA
AATCCAAGAGTAATCATGATGTCGCCAAGGCTGCACTGGATAAAGCCGAAGTAGAACTTGCCTACACCCGTCTGTTGGCC
CCCTATGATGGGGTGATTTCCAAGCGCGACAAACGCCAGTTTGAATATGTGCGGGCTCAGGAGCCTGTCCTGAGTGTGCG
CAGTGAAAACCTGATTGATGTGAATTTTCAGCTGCCTGAACAGTATATAAGCCCGATCCAAAGTTATCAGGCCAATACCG
GTAAGATACTGGTGCCGGAAGTACGTTTTGACAGCCGGGACTCCTGGTTTGCCGCGTCTCTGAAGGAGATGAGCACAGTG
GCCGACAGCAGTACCGGCAGTTACACAGTGATCCTGACGCTGCCAATGCCTGAGCAGCTCAACATTTTGCCGGGCATGTC
TGCAACGGTACGGGTATCCCTGCCTACCGAAACCCCAATCCCCCCGCCTGAGATCCCAGCTGGTGCTGTGGTGCAGGAAG
GAGATAAGACCTGGGTATTTCGCTGGTTGCCTGAGTCGCAGTTATTGCAAAAGGTGGAAGTGGTTCTCGAGGGCCACGTC
CTGGTCTCCGGGCTGAATGACGGCGACTTTGTCGTGGTGGCAGGCGCAGATGAACTCAAGGATGGCCAGAGCGCAGTGCG
CTGGGTGAAGGAGCGGGGGCTGTGA

Upstream 100 bases:

>100_bases
ACCGATTTGCTCATATCCCTTGCATTTATGTGGAAACTTATTGGTTTTGTTGTCAAACTGTTAACCACTTAATGCTGTTG
CACCTTTACAGGAGTTTCCC

Downstream 100 bases:

>100_bases
ACATGACAAGAATGATACTGATGCCTCTGGGGCTGATTGTGCTGCTGGGGAGCTGTCGTCAGGCACCGGATATTGAACAC
ACGCCTGCCAGAGTGGCGGT

Product: multidrug resistance protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSKLRPFSGIGIAAVLGGFLLSSATQGIAGEAPRPVKVSQIALADNMNQRLLPAEVRASERAGLSFRVSGEIMDILVRPG
EEVKAGQLLAKLDPALYEQQLAVAKAQYALAKVLYERNLSLVEQGVVSRNDFDKSKSNHDVAKAALDKAEVELAYTRLLA
PYDGVISKRDKRQFEYVRAQEPVLSVRSENLIDVNFQLPEQYISPIQSYQANTGKILVPEVRFDSRDSWFAASLKEMSTV
ADSSTGSYTVILTLPMPEQLNILPGMSATVRVSLPTETPIPPPEIPAGAVVQEGDKTWVFRWLPESQLLQKVEVVLEGHV
LVSGLNDGDFVVVAGADELKDGQSAVRWVKERGL

Sequences:

>Translated_354_residues
MSKLRPFSGIGIAAVLGGFLLSSATQGIAGEAPRPVKVSQIALADNMNQRLLPAEVRASERAGLSFRVSGEIMDILVRPG
EEVKAGQLLAKLDPALYEQQLAVAKAQYALAKVLYERNLSLVEQGVVSRNDFDKSKSNHDVAKAALDKAEVELAYTRLLA
PYDGVISKRDKRQFEYVRAQEPVLSVRSENLIDVNFQLPEQYISPIQSYQANTGKILVPEVRFDSRDSWFAASLKEMSTV
ADSSTGSYTVILTLPMPEQLNILPGMSATVRVSLPTETPIPPPEIPAGAVVQEGDKTWVFRWLPESQLLQKVEVVLEGHV
LVSGLNDGDFVVVAGADELKDGQSAVRWVKERGL
>Mature_353_residues
SKLRPFSGIGIAAVLGGFLLSSATQGIAGEAPRPVKVSQIALADNMNQRLLPAEVRASERAGLSFRVSGEIMDILVRPGE
EVKAGQLLAKLDPALYEQQLAVAKAQYALAKVLYERNLSLVEQGVVSRNDFDKSKSNHDVAKAALDKAEVELAYTRLLAP
YDGVISKRDKRQFEYVRAQEPVLSVRSENLIDVNFQLPEQYISPIQSYQANTGKILVPEVRFDSRDSWFAASLKEMSTVA
DSSTGSYTVILTLPMPEQLNILPGMSATVRVSLPTETPIPPPEIPAGAVVQEGDKTWVFRWLPESQLLQKVEVVLEGHVL
VSGLNDGDFVVVAGADELKDGQSAVRWVKERGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=306, Percent_Identity=26.1437908496732, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789929, Length=325, Percent_Identity=25.8461538461538, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38668; Mature: 38536

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLRPFSGIGIAAVLGGFLLSSATQGIAGEAPRPVKVSQIALADNMNQRLLPAEVRASE
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHH
RAGLSFRVSGEIMDILVRPGEEVKAGQLLAKLDPALYEQQLAVAKAQYALAKVLYERNLS
HCCEEEEECCCEEEEEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCHH
LVEQGVVSRNDFDKSKSNHDVAKAALDKAEVELAYTRLLAPYDGVISKRDKRQFEYVRAQ
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHC
EPVLSVRSENLIDVNFQLPEQYISPIQSYQANTGKILVPEVRFDSRDSWFAASLKEMSTV
CCHHHHCCCCEEEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
ADSSTGSYTVILTLPMPEQLNILPGMSATVRVSLPTETPIPPPEIPAGAVVQEGDKTWVF
HCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCEEEE
RWLPESQLLQKVEVVLEGHVLVSGLNDGDFVVVAGADELKDGQSAVRWVKERGL
EECCHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SKLRPFSGIGIAAVLGGFLLSSATQGIAGEAPRPVKVSQIALADNMNQRLLPAEVRASE
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHH
RAGLSFRVSGEIMDILVRPGEEVKAGQLLAKLDPALYEQQLAVAKAQYALAKVLYERNLS
HCCEEEEECCCEEEEEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCHH
LVEQGVVSRNDFDKSKSNHDVAKAALDKAEVELAYTRLLAPYDGVISKRDKRQFEYVRAQ
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHC
EPVLSVRSENLIDVNFQLPEQYISPIQSYQANTGKILVPEVRFDSRDSWFAASLKEMSTV
CCHHHHCCCCEEEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
ADSSTGSYTVILTLPMPEQLNILPGMSATVRVSLPTETPIPPPEIPAGAVVQEGDKTWVF
HCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCEEEE
RWLPESQLLQKVEVVLEGHVLVSGLNDGDFVVVAGADELKDGQSAVRWVKERGL
EECCHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]