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The map label for this gene is cadC [H]

Identifier: 119773745

GI number: 119773745

Start: 758871

End: 761060

Strand: Direct

Name: cadC [H]

Synonym: Sama_0607

Alternate gene names: 119773745

Gene position: 758871-761060 (Clockwise)

Preceding gene: 119773742

Following gene: 119773749

Centisome position: 17.62

GC content: 49.68

Gene sequence:

>2190_bases
ATGTTTAATAATAAAAAATACCGCCTCGGCCCCTACATGGTTATCCCAGAGCGGTGTGTGATTGCCAAAAACGGCTCTGA
CACCAAACTCGAACTGCGGGTGATGCAGGTATTGGTGTGTCTGCTGGAGCGTGCCGGTCGTCCCGTCAGTCGCGACGAGC
TTATCAGGGAAGTGTGGCGCGGTGGTCAGGTATCCGACAATGCCATCAACCGGATTATTGCTCAGCTCAGAAGCGCCTTG
GGCGACGACGCCCGCAGTCAGCAGGTTATTCAAACCGTCCCCAAGGTCGGTTATTTGCTGATAGCAGAGGTGGAACCACT
TGAAGGTCAGGTAATAACACCTTCCGATTTGACACACTCTTCAGAGGTCCCAAATGCAGCGGCTCCCGTGGCGCCGATAG
ACATTGAAGACAACCAGCAGCGCAGTTCCTCAACAATGTCACCAGACATTAAGCCCGTGCCTGCCCAGCCAAAGCCTGCC
CAGCTAAAGCCTGGCCGTCTCATCCTGGCGACTTACGCATTGGTGGGTGTACTCCTGTCTCTGTTGGCATTCATCGTCTG
GGATACTTTGACCCAGAGTGACAAGTCAAAAGCCGAACCCGTGCAAGACAACATAGCTTCATTGTTGCCGTTAACCTCTC
TGGAGGGGCAGGAGGTCGATCCGGTGTTATCACCGGATGGCAAAAAGCTGGCATTTGCCTTTCGGGACCTTAAAGCGAAA
GAGTGGCGTGTTCTGTTACAGGACCTGACTACGGGGCAAGTCTCTCTGGCTGACAACTCGCCAACAGCCTACAACCAGCG
CTATCCGGCCTGGAGCGATGATGGCGGCCATTTGGCGTACTTGAACTTTGATGGTAAAGGACGCTGCGAACTCATTCTGT
TGGATTTGCTCACCCGCAACGCAAAAGTAGTCTCCCAATGTGACAAAGCCACTCAATCGAGCGCTCTGGCCATAAGGGGG
CAGGAGCTCTATTTCGTGGACTCGGACGGCGTTGAAGATTTTAAAAAGATTTATCAGGTCAATCTGAATACCTTAAAGAA
AGAACAGCTCAGCCGCCCGCACAGTATAGGTCGGGGTGATTATGGCCTCAGCCTATCGCCGGATAAGTCGCAAATGGCGG
TGCTGAGAAACTTAAGCTGGTTTGATACTCAGTTGATGGTATTTAACTTCAGTACCGGGGAATGGCGACAGGTGCTTAAG
GTGGGTTACCCATTAAAGAGCATAGCCTGGTCTGCCGATGGTAAGGGGTTGATCTATAGGGCGGAAGAAGGCCAACTGCA
CCGTTTCGATTTAGACACCAAAGATCGCGTTCGACTGACCAAGATACTGCAGGAAATCAACTCACCTCGCTCAAACAGCA
AGGGGCAAACGGTAGCTGTCGTCGGCGAGCTAATGGAAGAAGAACTGTGGCATTGGTCAGCGCCGGGTAATACCAAACCC
GAGCCATGGGTATCATCCAGTCGCCGCGATTATCGTGGTGCTATCAGTCCAGATGGCACCTTGACGGCTTTCGTCTCCAA
TCGAACCGGGTTGCCACAAATATGGCTGAGGCAACTGAAAGGTGAAGAAATCAAACTCACCCATTTTGACCGGTTTTCAT
TTATAGACGAGCTGATATTTTCCCCGAATGGCAAATTGCTTGCTGGCACTATTAATGGCGCAGCCTTCACCTTGGATATT
GCCAAGTCGGCAATTCATTTTATTCCGGGCAGAACTTCGGTGAGAAATATTTCATTTGGGATGAATGATGATGAATTGGT
GCTGTTTTCCTCTGAAGCTGGTAAGCGTCAACTTCAACTGGTGGATATGCGAACTGGAAAAACGCTCAATCTGTTGGCCG
AAAATGGTTTTTCCGGAAAATTTGATAGAGCCTCTGGCGAGTTTTTTTATTCTAAAATGAACAGTTCGGGAATATGGAGT
TTAACCCAGGGGGTGGAAACACAAGTCACCGATAAAGTCACGCCCCTCTTTTCCGGTGGTTGGCATGTGGCCCAAGGCAA
AATCTGGTACCTGAAAGGTGATGAGGGAACAACCAAACTCATGGAGCTGGACGTCAATAATGACAAAGAGTTTGCGCATC
CAATACAAATTACCAATGTATCTATGAACACACTCTCAATGACCAACAACAACCAAGTGCTCTTGTCTGTGTTGGCCAAT
GCCAATACAGATATATTTTTGGTGAATTAA

Upstream 100 bases:

>100_bases
GGCAAGCCTAAAGCAGGCTTTCTTGGTTCTTTGCTTCCACTCCTTCGCCGATATTGATTAAATAACACAAAAATAAAGAC
TGGGTCACAAAGCGAACAGC

Downstream 100 bases:

>100_bases
ATCAGTTTCTTGTGTGTTCGTCACTTTTTCATAACCTTTTCCTTGTCGCCAAATCAGAACGCCCGGGCCTAATGTTTAAC
TCGTCAACTGGCCCGGTTGC

Product: putative transcriptional regulator, CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MFNNKKYRLGPYMVIPERCVIAKNGSDTKLELRVMQVLVCLLERAGRPVSRDELIREVWRGGQVSDNAINRIIAQLRSAL
GDDARSQQVIQTVPKVGYLLIAEVEPLEGQVITPSDLTHSSEVPNAAAPVAPIDIEDNQQRSSSTMSPDIKPVPAQPKPA
QLKPGRLILATYALVGVLLSLLAFIVWDTLTQSDKSKAEPVQDNIASLLPLTSLEGQEVDPVLSPDGKKLAFAFRDLKAK
EWRVLLQDLTTGQVSLADNSPTAYNQRYPAWSDDGGHLAYLNFDGKGRCELILLDLLTRNAKVVSQCDKATQSSALAIRG
QELYFVDSDGVEDFKKIYQVNLNTLKKEQLSRPHSIGRGDYGLSLSPDKSQMAVLRNLSWFDTQLMVFNFSTGEWRQVLK
VGYPLKSIAWSADGKGLIYRAEEGQLHRFDLDTKDRVRLTKILQEINSPRSNSKGQTVAVVGELMEEELWHWSAPGNTKP
EPWVSSSRRDYRGAISPDGTLTAFVSNRTGLPQIWLRQLKGEEIKLTHFDRFSFIDELIFSPNGKLLAGTINGAAFTLDI
AKSAIHFIPGRTSVRNISFGMNDDELVLFSSEAGKRQLQLVDMRTGKTLNLLAENGFSGKFDRASGEFFYSKMNSSGIWS
LTQGVETQVTDKVTPLFSGGWHVAQGKIWYLKGDEGTTKLMELDVNNDKEFAHPIQITNVSMNTLSMTNNNQVLLSVLAN
ANTDIFLVN

Sequences:

>Translated_729_residues
MFNNKKYRLGPYMVIPERCVIAKNGSDTKLELRVMQVLVCLLERAGRPVSRDELIREVWRGGQVSDNAINRIIAQLRSAL
GDDARSQQVIQTVPKVGYLLIAEVEPLEGQVITPSDLTHSSEVPNAAAPVAPIDIEDNQQRSSSTMSPDIKPVPAQPKPA
QLKPGRLILATYALVGVLLSLLAFIVWDTLTQSDKSKAEPVQDNIASLLPLTSLEGQEVDPVLSPDGKKLAFAFRDLKAK
EWRVLLQDLTTGQVSLADNSPTAYNQRYPAWSDDGGHLAYLNFDGKGRCELILLDLLTRNAKVVSQCDKATQSSALAIRG
QELYFVDSDGVEDFKKIYQVNLNTLKKEQLSRPHSIGRGDYGLSLSPDKSQMAVLRNLSWFDTQLMVFNFSTGEWRQVLK
VGYPLKSIAWSADGKGLIYRAEEGQLHRFDLDTKDRVRLTKILQEINSPRSNSKGQTVAVVGELMEEELWHWSAPGNTKP
EPWVSSSRRDYRGAISPDGTLTAFVSNRTGLPQIWLRQLKGEEIKLTHFDRFSFIDELIFSPNGKLLAGTINGAAFTLDI
AKSAIHFIPGRTSVRNISFGMNDDELVLFSSEAGKRQLQLVDMRTGKTLNLLAENGFSGKFDRASGEFFYSKMNSSGIWS
LTQGVETQVTDKVTPLFSGGWHVAQGKIWYLKGDEGTTKLMELDVNNDKEFAHPIQITNVSMNTLSMTNNNQVLLSVLAN
ANTDIFLVN
>Mature_729_residues
MFNNKKYRLGPYMVIPERCVIAKNGSDTKLELRVMQVLVCLLERAGRPVSRDELIREVWRGGQVSDNAINRIIAQLRSAL
GDDARSQQVIQTVPKVGYLLIAEVEPLEGQVITPSDLTHSSEVPNAAAPVAPIDIEDNQQRSSSTMSPDIKPVPAQPKPA
QLKPGRLILATYALVGVLLSLLAFIVWDTLTQSDKSKAEPVQDNIASLLPLTSLEGQEVDPVLSPDGKKLAFAFRDLKAK
EWRVLLQDLTTGQVSLADNSPTAYNQRYPAWSDDGGHLAYLNFDGKGRCELILLDLLTRNAKVVSQCDKATQSSALAIRG
QELYFVDSDGVEDFKKIYQVNLNTLKKEQLSRPHSIGRGDYGLSLSPDKSQMAVLRNLSWFDTQLMVFNFSTGEWRQVLK
VGYPLKSIAWSADGKGLIYRAEEGQLHRFDLDTKDRVRLTKILQEINSPRSNSKGQTVAVVGELMEEELWHWSAPGNTKP
EPWVSSSRRDYRGAISPDGTLTAFVSNRTGLPQIWLRQLKGEEIKLTHFDRFSFIDELIFSPNGKLLAGTINGAAFTLDI
AKSAIHFIPGRTSVRNISFGMNDDELVLFSSEAGKRQLQLVDMRTGKTLNLLAENGFSGKFDRASGEFFYSKMNSSGIWS
LTQGVETQVTDKVTPLFSGGWHVAQGKIWYLKGDEGTTKLMELDVNNDKEFAHPIQITNVSMNTLSMTNNNQVLLSVLAN
ANTDIFLVN

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: COG3710

COG function: function code K; DNA-binding winged-HTH domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=195, Percent_Identity=30.2564102564103, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 80975; Mature: 80975

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNNKKYRLGPYMVIPERCVIAKNGSDTKLELRVMQVLVCLLERAGRPVSRDELIREVWR
CCCCCEEECCCEEECCCEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GGQVSDNAINRIIAQLRSALGDDARSQQVIQTVPKVGYLLIAEVEPLEGQVITPSDLTHS
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCC
SEVPNAAAPVAPIDIEDNQQRSSSTMSPDIKPVPAQPKPAQLKPGRLILATYALVGVLLS
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LLAFIVWDTLTQSDKSKAEPVQDNIASLLPLTSLEGQEVDPVLSPDGKKLAFAFRDLKAK
HHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCHH
EWRVLLQDLTTGQVSLADNSPTAYNQRYPAWSDDGGHLAYLNFDGKGRCELILLDLLTRN
HHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEHHHCC
AKVVSQCDKATQSSALAIRGQELYFVDSDGVEDFKKIYQVNLNTLKKEQLSRPHSIGRGD
HHHHHHHHHHHCCCEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YGLSLSPDKSQMAVLRNLSWFDTQLMVFNFSTGEWRQVLKVGYPLKSIAWSADGKGLIYR
CCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHEECCCCCEEEEE
AEEGQLHRFDLDTKDRVRLTKILQEINSPRSNSKGQTVAVVGELMEEELWHWSAPGNTKP
CCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHEECCCCCCCC
EPWVSSSRRDYRGAISPDGTLTAFVSNRTGLPQIWLRQLKGEEIKLTHFDRFSFIDELIF
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHH
SPNGKLLAGTINGAAFTLDIAKSAIHFIPGRTSVRNISFGMNDDELVLFSSEAGKRQLQL
CCCCCEEEEEECCEEEEEEHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCEEEEE
VDMRTGKTLNLLAENGFSGKFDRASGEFFYSKMNSSGIWSLTQGVETQVTDKVTPLFSGG
EEECCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEECCCCCHHHHHCCCEEECCC
WHVAQGKIWYLKGDEGTTKLMELDVNNDKEFAHPIQITNVSMNTLSMTNNNQVLLSVLAN
EEEECCEEEEEECCCCCEEEEEEECCCCCCCCCCEEEEEEEEEEEEECCCCEEEEEEECC
ANTDIFLVN
CCCCEEEEC
>Mature Secondary Structure
MFNNKKYRLGPYMVIPERCVIAKNGSDTKLELRVMQVLVCLLERAGRPVSRDELIREVWR
CCCCCEEECCCEEECCCEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GGQVSDNAINRIIAQLRSALGDDARSQQVIQTVPKVGYLLIAEVEPLEGQVITPSDLTHS
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCC
SEVPNAAAPVAPIDIEDNQQRSSSTMSPDIKPVPAQPKPAQLKPGRLILATYALVGVLLS
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LLAFIVWDTLTQSDKSKAEPVQDNIASLLPLTSLEGQEVDPVLSPDGKKLAFAFRDLKAK
HHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCHH
EWRVLLQDLTTGQVSLADNSPTAYNQRYPAWSDDGGHLAYLNFDGKGRCELILLDLLTRN
HHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEHHHCC
AKVVSQCDKATQSSALAIRGQELYFVDSDGVEDFKKIYQVNLNTLKKEQLSRPHSIGRGD
HHHHHHHHHHHCCCEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YGLSLSPDKSQMAVLRNLSWFDTQLMVFNFSTGEWRQVLKVGYPLKSIAWSADGKGLIYR
CCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHEECCCCCEEEEE
AEEGQLHRFDLDTKDRVRLTKILQEINSPRSNSKGQTVAVVGELMEEELWHWSAPGNTKP
CCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHEECCCCCCCC
EPWVSSSRRDYRGAISPDGTLTAFVSNRTGLPQIWLRQLKGEEIKLTHFDRFSFIDELIF
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHH
SPNGKLLAGTINGAAFTLDIAKSAIHFIPGRTSVRNISFGMNDDELVLFSSEAGKRQLQL
CCCCCEEEEEECCEEEEEEHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCEEEEE
VDMRTGKTLNLLAENGFSGKFDRASGEFFYSKMNSSGIWSLTQGVETQVTDKVTPLFSGG
EEECCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEECCCCCHHHHHCCCEEECCC
WHVAQGKIWYLKGDEGTTKLMELDVNNDKEFAHPIQITNVSMNTLSMTNNNQVLLSVLAN
EEEECCEEEEEECCCCCEEEEEEECCCCCCCCCCEEEEEEEEEEEEECCCCEEEEEEECC
ANTDIFLVN
CCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]