Click here to switch to the map view.

The map label for this gene is trkH [H]

Identifier: 119773177

GI number: 119773177

Start: 38875

End: 40332

Strand: Direct

Name: trkH [H]

Synonym: Sama_0035

Alternate gene names: 119773177

Gene position: 38875-40332 (Clockwise)

Preceding gene: 119773176

Following gene: 119773178

Centisome position: 0.9

GC content: 52.95

Gene sequence:

>1458_bases
ATGCAATACAGAACAATAATAAGGATCACCGGCCTGTTGATGGGGTTGTTTTCCATCACCATGTTGCCACCGGCGCTGGT
CGCTATCTATTACAAAGATGGCGGCGGTACTGCATTTATTCAGGCCTTTGTGGTGAGTCTGATCCTGGGCTTTATTTTTT
GGTATCCCAATCGCAAGCATAAGTCGGAGCTGCGCACCCGCGAAGGCTTCCTGATTGTGGTGCTGTTCTGGACGGTTCTG
GGGTCTATCGGTGCTTTGCCATTTATTTTCTCATCCACACCGGATTTAAGCTGGACCGATTCCTTCTTTGAGTCTTTTTC
GGCGCTCACCACCACGGGAGCGACCGTGATTGTGGGGCTCGACAGCCTGCCCAAGGCAATTCTGTTCTACAGGCACTTGC
TGCAGTGGTTGGGGGGGATGGGGATCATCGTGCTCGCGGTAGCCATCTTACCCGTGCTTGGTATCGGTGGCATGCAGTTG
TACCGCGCCGAAATTCCCGGTCCGGTCAAAGACAGCAAAATGACTCCGCGCATCGCCGAGACCGCCAAGGCGCTTTGGTA
CATTTACCTGCTACTTACCATTGCCTGTGCCACAGCCTACTGGGCCGCGGGCATGTCAGTATTTGATGCGATTTGCCACT
CGTTCTCCACCATTGCCATCGGTGGTTTCTCTACCCACGATGCCAGTATGGGGTATTTCGATAGTCCGACCATCAATATG
ATTTGTGTCGTATTTTTGATTATTGCCGCAGTGAATTTCAGTGTGCACTTTGCCGCCATGAGCCGCAGGGGCATCAACCT
CAGGGTGTATTTCCGTGACACCGAATTCAAGATTCTGGTCGCGATTCAGCTGCTATTAACCGCCATCTGTTTTGCGACGC
TCTACCATTCAGGAATTTACGACTCGCCGGAAGAAACCTTCGATTACGCGCTGTTTCAGGCGGTGTCTATTTCCACGACT
GCAGGTTTCGGCACCGAGAGTTTCCACCTATGGCCGCTGTTTTTGCCCATGTTGCTGATTTTTTCAAGCTTTATTGGTGG
CTGTGGTGGCTCTACCGCAGGGGGGATCAAGGTTATTCGGGTCGTACTTCTGCTGCTGCAGGGAAGTCGGGAACTGAAAC
GCCTTATCCACCCCAGAGCCATGTTTTCTATCCGCATCGGCAAAACCGCGCTGCCGGATCGGGTCGTGGACGCTGTGTGG
GGTTTTTTCTCGGCGTACGCCCTGGTATTCGTTATCTGTATGCTGATATTGATGGCCATGGGGCTGGATGACATTACCGC
CTTCAGTGCCACGGCTGCCTGTCTGAATAACCTTGGCCCGGGTCTGGGTGAAGTGGCCAGCAACTATGCCAGTATAGGTG
ATGGCGCCAAGTGGGTACTGGTCGTGGCCATGTTGTTTGGGCGGCTCGAAATCTTTACCCTGTTGGTGCTTTTTACCCCC
ACTTTCTGGAGAACCTGA

Upstream 100 bases:

>100_bases
ATTTTGATGACCGTGAATGAGTGCCAGTGAAGGGGAATTGTGCGACAATCCCTCAATTACTCAAAAAGCGCCCGGCATCA
AGGGAATACCAGACCGCTCC

Downstream 100 bases:

>100_bases
TGACCCATACCTTGATCCTCTATTCCACCGTGGACGGCCAGACCCGCAAAATATGTGAGCGCATCAAGGCACGCTGTGAG
GCGGCAGGCGAGCAGGTCAC

Product: TrkH family potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MQYRTIIRITGLLMGLFSITMLPPALVAIYYKDGGGTAFIQAFVVSLILGFIFWYPNRKHKSELRTREGFLIVVLFWTVL
GSIGALPFIFSSTPDLSWTDSFFESFSALTTTGATVIVGLDSLPKAILFYRHLLQWLGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLLLTIACATAYWAAGMSVFDAICHSFSTIAIGGFSTHDASMGYFDSPTINM
ICVVFLIIAAVNFSVHFAAMSRRGINLRVYFRDTEFKILVAIQLLLTAICFATLYHSGIYDSPEETFDYALFQAVSISTT
AGFGTESFHLWPLFLPMLLIFSSFIGGCGGSTAGGIKVIRVVLLLLQGSRELKRLIHPRAMFSIRIGKTALPDRVVDAVW
GFFSAYALVFVICMLILMAMGLDDITAFSATAACLNNLGPGLGEVASNYASIGDGAKWVLVVAMLFGRLEIFTLLVLFTP
TFWRT

Sequences:

>Translated_485_residues
MQYRTIIRITGLLMGLFSITMLPPALVAIYYKDGGGTAFIQAFVVSLILGFIFWYPNRKHKSELRTREGFLIVVLFWTVL
GSIGALPFIFSSTPDLSWTDSFFESFSALTTTGATVIVGLDSLPKAILFYRHLLQWLGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLLLTIACATAYWAAGMSVFDAICHSFSTIAIGGFSTHDASMGYFDSPTINM
ICVVFLIIAAVNFSVHFAAMSRRGINLRVYFRDTEFKILVAIQLLLTAICFATLYHSGIYDSPEETFDYALFQAVSISTT
AGFGTESFHLWPLFLPMLLIFSSFIGGCGGSTAGGIKVIRVVLLLLQGSRELKRLIHPRAMFSIRIGKTALPDRVVDAVW
GFFSAYALVFVICMLILMAMGLDDITAFSATAACLNNLGPGLGEVASNYASIGDGAKWVLVVAMLFGRLEIFTLLVLFTP
TFWRT
>Mature_485_residues
MQYRTIIRITGLLMGLFSITMLPPALVAIYYKDGGGTAFIQAFVVSLILGFIFWYPNRKHKSELRTREGFLIVVLFWTVL
GSIGALPFIFSSTPDLSWTDSFFESFSALTTTGATVIVGLDSLPKAILFYRHLLQWLGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLLLTIACATAYWAAGMSVFDAICHSFSTIAIGGFSTHDASMGYFDSPTINM
ICVVFLIIAAVNFSVHFAAMSRRGINLRVYFRDTEFKILVAIQLLLTAICFATLYHSGIYDSPEETFDYALFQAVSISTT
AGFGTESFHLWPLFLPMLLIFSSFIGGCGGSTAGGIKVIRVVLLLLQGSRELKRLIHPRAMFSIRIGKTALPDRVVDAVW
GFFSAYALVFVICMLILMAMGLDDITAFSATAACLNNLGPGLGEVASNYASIGDGAKWVLVVAMLFGRLEIFTLLVLFTP
TFWRT

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=484, Percent_Identity=65.0826446280992, Blast_Score=621, Evalue=1e-179,
Organism=Escherichia coli, GI1787626, Length=482, Percent_Identity=42.9460580912863, Blast_Score=410, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53161; Mature: 53161

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYRTIIRITGLLMGLFSITMLPPALVAIYYKDGGGTAFIQAFVVSLILGFIFWYPNRKH
CCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCH
KSELRTREGFLIVVLFWTVLGSIGALPFIFSSTPDLSWTDSFFESFSALTTTGATVIVGL
HHHHHHCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
DSLPKAILFYRHLLQWLGGMGIIVLAVAILPVLGIGGMQLYRAEIPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCHHHH
TAKALWYIYLLLTIACATAYWAAGMSVFDAICHSFSTIAIGGFSTHDASMGYFDSPTINM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHH
ICVVFLIIAAVNFSVHFAAMSRRGINLRVYFRDTEFKILVAIQLLLTAICFATLYHSGIY
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
DSPEETFDYALFQAVSISTTAGFGTESFHLWPLFLPMLLIFSSFIGGCGGSTAGGIKVIR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VVLLLLQGSRELKRLIHPRAMFSIRIGKTALPDRVVDAVWGFFSAYALVFVICMLILMAM
HHHHHHCCCHHHHHHHCCHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLDDITAFSATAACLNNLGPGLGEVASNYASIGDGAKWVLVVAMLFGRLEIFTLLVLFTP
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TFWRT
HHCCC
>Mature Secondary Structure
MQYRTIIRITGLLMGLFSITMLPPALVAIYYKDGGGTAFIQAFVVSLILGFIFWYPNRKH
CCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCH
KSELRTREGFLIVVLFWTVLGSIGALPFIFSSTPDLSWTDSFFESFSALTTTGATVIVGL
HHHHHHCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
DSLPKAILFYRHLLQWLGGMGIIVLAVAILPVLGIGGMQLYRAEIPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCHHHH
TAKALWYIYLLLTIACATAYWAAGMSVFDAICHSFSTIAIGGFSTHDASMGYFDSPTINM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHH
ICVVFLIIAAVNFSVHFAAMSRRGINLRVYFRDTEFKILVAIQLLLTAICFATLYHSGIY
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
DSPEETFDYALFQAVSISTTAGFGTESFHLWPLFLPMLLIFSSFIGGCGGSTAGGIKVIR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VVLLLLQGSRELKRLIHPRAMFSIRIGKTALPDRVVDAVWGFFSAYALVFVICMLILMAM
HHHHHHCCCHHHHHHHCCHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLDDITAFSATAACLNNLGPGLGEVASNYASIGDGAKWVLVVAMLFGRLEIFTLLVLFTP
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TFWRT
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]