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The map label for this gene is yeiI [H]

Identifier: 119718839

GI number: 119718839

Start: 4899480

End: 4900589

Strand: Reverse

Name: yeiI [H]

Synonym: Noca_4622

Alternate gene names: 119718839

Gene position: 4900589-4899480 (Counterclockwise)

Preceding gene: 119718840

Following gene: 119718838

Centisome position: 98.29

GC content: 74.86

Gene sequence:

>1110_bases
ATGAACCTCACCGAGCGCGAGCAGGAGATCGTGACCCTGCTGCGGCGCGATCCGCTCGTCAGCTCGGCGGCGATCGCCGA
AGCGCTCGGGACCACCCGCGCCGCCGTCAACGTGCATGTCTCGAACCTCACCCGCAAGGGCATCGTCCTCGGCCGGGGCT
ACGTGCTGAACGAGGGCCCCTCGGTGGTGGTCGTCGGCGGCGCCAACATGGACGTCAAGGCCCGCAGCACCCGCGCCGCC
GTGGTCGCCACCAGCAACCCCGGCACGGCCGCGATGGCCGCCGGCGGGGTCGGTCGCAACATCGCCGAGAACCTGGCCCG
ACTCGGCACCCGGACCCACCTGGTCGCCGCGATCGGCAGCGACGCGCTCGGGGACCAGGTGCTCGCCGCGACCTCGAACG
CAGGGGTGGTGGTGGAGCACGTACGCCGCAGCGCCCGGTCGACCGGCACCTACACCGCGGTCCTCGACGCCGACGGCGAG
CTGGTCGTCGCGGTCGCCGACATGGCCGCCACCGACGAGCTCCTGCCTGACCAGGTCGCGGCGGCGCGCGACCTGGTGTC
CGCCGCGTCGCTGGTCGTCCTCGACGGGAACCTCTCGACCGGCACGCTGCGCTACGCCCTCGACCTGGCCGCGGAGGTCG
GCACCCGGGTGCTGCTGGACCCGGTCAGCGTCCCGAAGGCTGCCGCGCTCGCGCCGCTCGTCACCGTCGACCGGCCGGTG
TTCACGGTGACCCCCAACCGCGACGAGCTCGCGGCCCTGACCGATCTCCCGACCCGGACCCGGCGCCAGCAGGAGGCGGC
GGCGCGGGCCCTGCACGACCGCGGCGTCCAGCTGGTCTGGGTGCGGCTCGGCCCGGCCGGCTCGCTGCTCAGCTCACCGA
CCGGCGTCGTCGCCCTGGAGGCCGTCCCGGCGGGGGTGGCCGGGGAGGTCACCGACGTGACCGGCGCGGGCGATGCGATG
ACAGCGGCCTTCTGCCACGCCCTGCTGACCGGCTCCGACCCGGCCGAGGCCGCGGCGTACGGCCACGCCGCCGCCGCCCT
CACCGTCGCCAGCACCGACACCGTCCGAACCGACCTCACCGACCGACTCGTCAGGAGCCTGCTGTCATGA

Upstream 100 bases:

>100_bases
TCGGGCTGGTGCTCGCCGTACCCCTCACCACCGGGATCGCGGCGCTCGTCATCCCCGGGCCTCTTGCTTATTCGGATAAG
GATGCTTTAGAGTAGTAAGC

Downstream 100 bases:

>100_bases
CCGCACCTCACCCCCTGCTCACCCTCACCGACGAGGTCGCCGACGCGCTGCGCGACGGCGCCCCGGTGGTCGCGCTGGAG
AGCACGATCATCAGCCACGG

Product: ribokinase-like domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MNLTEREQEIVTLLRRDPLVSSAAIAEALGTTRAAVNVHVSNLTRKGIVLGRGYVLNEGPSVVVVGGANMDVKARSTRAA
VVATSNPGTAAMAAGGVGRNIAENLARLGTRTHLVAAIGSDALGDQVLAATSNAGVVVEHVRRSARSTGTYTAVLDADGE
LVVAVADMAATDELLPDQVAAARDLVSAASLVVLDGNLSTGTLRYALDLAAEVGTRVLLDPVSVPKAAALAPLVTVDRPV
FTVTPNRDELAALTDLPTRTRRQQEAAARALHDRGVQLVWVRLGPAGSLLSSPTGVVALEAVPAGVAGEVTDVTGAGDAM
TAAFCHALLTGSDPAEAAAYGHAAAALTVASTDTVRTDLTDRLVRSLLS

Sequences:

>Translated_369_residues
MNLTEREQEIVTLLRRDPLVSSAAIAEALGTTRAAVNVHVSNLTRKGIVLGRGYVLNEGPSVVVVGGANMDVKARSTRAA
VVATSNPGTAAMAAGGVGRNIAENLARLGTRTHLVAAIGSDALGDQVLAATSNAGVVVEHVRRSARSTGTYTAVLDADGE
LVVAVADMAATDELLPDQVAAARDLVSAASLVVLDGNLSTGTLRYALDLAAEVGTRVLLDPVSVPKAAALAPLVTVDRPV
FTVTPNRDELAALTDLPTRTRRQQEAAARALHDRGVQLVWVRLGPAGSLLSSPTGVVALEAVPAGVAGEVTDVTGAGDAM
TAAFCHALLTGSDPAEAAAYGHAAAALTVASTDTVRTDLTDRLVRSLLS
>Mature_369_residues
MNLTEREQEIVTLLRRDPLVSSAAIAEALGTTRAAVNVHVSNLTRKGIVLGRGYVLNEGPSVVVVGGANMDVKARSTRAA
VVATSNPGTAAMAAGGVGRNIAENLARLGTRTHLVAAIGSDALGDQVLAATSNAGVVVEHVRRSARSTGTYTAVLDADGE
LVVAVADMAATDELLPDQVAAARDLVSAASLVVLDGNLSTGTLRYALDLAAEVGTRVLLDPVSVPKAAALAPLVTVDRPV
FTVTPNRDELAALTDLPTRTRRQQEAAARALHDRGVQLVWVRLGPAGSLLSSPTGVVALEAVPAGVAGEVTDVTGAGDAM
TAAFCHALLTGSDPAEAAAYGHAAAALTVASTDTVRTDLTDRLVRSLLS

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=239, Percent_Identity=28.0334728033473, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788484, Length=350, Percent_Identity=35.4285714285714, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1788491, Length=316, Percent_Identity=32.5949367088608, Blast_Score=148, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=25.6666666666667, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24580669, Length=302, Percent_Identity=25.8278145695364, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: NA

Molecular weight: Translated: 37601; Mature: 37601

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTEREQEIVTLLRRDPLVSSAAIAEALGTTRAAVNVHVSNLTRKGIVLGRGYVLNEGP
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCEEECCCC
SVVVVGGANMDVKARSTRAAVVATSNPGTAAMAAGGVGRNIAENLARLGTRTHLVAAIGS
CEEEECCCCCCEEECCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHCCHHEEEEECCC
DALGDQVLAATSNAGVVVEHVRRSARSTGTYTAVLDADGELVVAVADMAATDELLPDQVA
CCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECHHHHHHHCHHHHH
AARDLVSAASLVVLDGNLSTGTLRYALDLAAEVGTRVLLDPVSVPKAAALAPLVTVDRPV
HHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHEEEECCCE
FTVTPNRDELAALTDLPTRTRRQQEAAARALHDRGVQLVWVRLGPAGSLLSSPTGVVALE
EEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHCCCCCEEEEE
AVPAGVAGEVTDVTGAGDAMTAAFCHALLTGSDPAEAAAYGHAAAALTVASTDTVRTDLT
ECCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHEEEEEECCCCHHHHHH
DRLVRSLLS
HHHHHHHHC
>Mature Secondary Structure
MNLTEREQEIVTLLRRDPLVSSAAIAEALGTTRAAVNVHVSNLTRKGIVLGRGYVLNEGP
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCEEECCCC
SVVVVGGANMDVKARSTRAAVVATSNPGTAAMAAGGVGRNIAENLARLGTRTHLVAAIGS
CEEEECCCCCCEEECCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHCCHHEEEEECCC
DALGDQVLAATSNAGVVVEHVRRSARSTGTYTAVLDADGELVVAVADMAATDELLPDQVA
CCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECHHHHHHHCHHHHH
AARDLVSAASLVVLDGNLSTGTLRYALDLAAEVGTRVLLDPVSVPKAAALAPLVTVDRPV
HHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHEEEECCCE
FTVTPNRDELAALTDLPTRTRRQQEAAARALHDRGVQLVWVRLGPAGSLLSSPTGVVALE
EEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHCCCCCEEEEE
AVPAGVAGEVTDVTGAGDAMTAAFCHALLTGSDPAEAAAYGHAAAALTVASTDTVRTDLT
ECCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHEEEEEECCCCHHHHHH
DRLVRSLLS
HHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 2460435 [H]