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The map label for this gene is glmS [H]

Identifier: 119718819

GI number: 119718819

Start: 4876868

End: 4878700

Strand: Reverse

Name: glmS [H]

Synonym: Noca_4602

Alternate gene names: 119718819

Gene position: 4878700-4876868 (Counterclockwise)

Preceding gene: 119718820

Following gene: 119718818

Centisome position: 97.85

GC content: 72.34

Gene sequence:

>1833_bases
ATGTGCGGAATCGTCGGATACGTCGGTGCCCAGCAGGCCGCCCCGATCCTGGTCGAGGGACTGACCCGCCTCGAGCACCG
GGGCTACGACTCGGCCGGCCTGGCGGTGCTCGCGGGGAGCGGCATCAAGGTCGCGAAGCGGGCCGGGCGCGTGCGCGACC
TCGCCGACAGCCTGCCCAAGCGCTTCGCCGGCAAGGTCGGCATCGGGCACACCCGCTGGGCCACCCACGGCCCGGCCAAC
GACGTCAACGCGCATCCCCACAGCGACGCCAAGGGCCTGGTGTCGGTGGTGCACAACGGGATCATCGACAACGCCGCGGC
GCTCCGGCACCGTCTTGCCGACGAGGGCGTCGACCTGGTCAGCGACACCGACACCGAGGTGCTCGCGCACCTGGTCGCAC
GGTCGAGCGCCGACACGCTCGAGGGCAAGGTGAGCCAGGCGCTCGCCGCGATCGAGGGCACCTACGGGATCGCGGTGCTG
CACGTCGACTTCCCCGACCGGGTCGTCGTCGCCCGCAACGGCAGTCCGCTGATCGTGGGCGTCGGGGAGCGCGAGATGTT
CGTGGCCTCGGACCTCGCCGCGATCGTGCGGCACACCACGACGGTCGCCCACCTCGACGACGGCGAGCTGGCCACCGTGA
CCGCGACCGGCTTCACGACCTACCGGCAGGACCTCACGGCGACCGCGAAGTCCGCCACGGTGCTGGACGTCGACCCCTCG
TCGTACGACGCGGGCGAGCACGACTCGTTCATGCGCAAGGAGATGTTCGAGCAGCCCTCGGCCGCCGAGCGGGTGCTGCG
CGGCCGGCTCGACGAGCGGTTCGGGACCGCCCACCTCGGCGGGCTGAACCTGGACCCCCGGGAGAACCGCGCGATCCGGC
GGGTCAAGATCCTCGGCTGCGGCTCGGCCTACTACGTGGGCCAGATGGGGGCCGAGCTCGTCGAGGAGCTGGCGCGGATC
CCGGCGGACGCGGAGGCGGCCAGCGAGTTCCGCTACCGCAACCCGATCATCGAGCCGGACACGCTCTACGTCGCGGTGAG
CCAGTCGGGGGAGACCATCGACACCCTGCTCGCGGTGCAGGAGATCCGGCGCAAGGGCGGCCGGGTGGTCGGCCTGGTCA
ACGTGGTCGGCAGCGCGATCGCGCGGGAGTGCGACGGGGGCATCTACCTCCACGCCGGACCGGAGGTCGCGGTCGCCTCG
ACGAAGGCACTGACGAACATGTTCCTCGGCTTCGCGCTGCTCGCCCTCCAGCTCGGCCGGGTGCGCGACCTCTCGATCGC
CGACGGGCGGCGGCTGATCGCCGGCCTTGCCCGGCTCCCCGGGCAGATCGAGGAGGTGTTGGCCCAGGAGGGCGCGCTCG
CCGAGCTCGCCGGCCGGCTGGCCGAGGCGGAGAGCCTGTTCTTCGTGGGCCGGGTGCGCGGCTACCCGGTCGCCCGCGAG
GGCGCGCAGAAGTTCAAGGAGATCTCCTACCGGCACGCGGAGGCCTACCAGACCTCCGAGCTCAAGCACGGACCGCTGGC
GCTGATCTGCGAGACGGTGCCCACCGTCGCGATCGTCCCGGCCGACGAGCTCACCGACCGCAACGTGGGCGCCCTGCACG
AGATCGCGGCCCGCCGCGGCCCGCTGGTCGTCGTGACCCACGACGACGTCGACCTCGGCGACCTCGCGGACCGACCCGAG
GTGCAGCGGGTCGTCGTACCCCGCAACGAGCGCGAGCTCGACCCGATCCTGCTCACGGTCCCGCTCCAGCTGCTCGCCTA
CCACGCGGCGCTGCGCCTCGGCCACGACATCGACAAGCCGCGCAACCTGGCGAAGAGCGTGACGGTCGAGTAG

Upstream 100 bases:

>100_bases
GTCAGCGGACCCGCTGATGGTGGTCGAGCGAGCCGCGCGACCGAGGAACCGAGGTCGCGACCGGCGTGTCGAGACCCAGT
AGTGAGAGGACACGCCCACC

Downstream 100 bases:

>100_bases
GTGGCCCCCGAGAGGTGACGCAGCGCACCGCGACGACGAATCCGCCGGTGGCCGCCGCACCCACTACCGTTGACGGGTGA
GCAGCGACGAGCAGGACGAC

Product: glutamine--fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MCGIVGYVGAQQAAPILVEGLTRLEHRGYDSAGLAVLAGSGIKVAKRAGRVRDLADSLPKRFAGKVGIGHTRWATHGPAN
DVNAHPHSDAKGLVSVVHNGIIDNAAALRHRLADEGVDLVSDTDTEVLAHLVARSSADTLEGKVSQALAAIEGTYGIAVL
HVDFPDRVVVARNGSPLIVGVGEREMFVASDLAAIVRHTTTVAHLDDGELATVTATGFTTYRQDLTATAKSATVLDVDPS
SYDAGEHDSFMRKEMFEQPSAAERVLRGRLDERFGTAHLGGLNLDPRENRAIRRVKILGCGSAYYVGQMGAELVEELARI
PADAEAASEFRYRNPIIEPDTLYVAVSQSGETIDTLLAVQEIRRKGGRVVGLVNVVGSAIARECDGGIYLHAGPEVAVAS
TKALTNMFLGFALLALQLGRVRDLSIADGRRLIAGLARLPGQIEEVLAQEGALAELAGRLAEAESLFFVGRVRGYPVARE
GAQKFKEISYRHAEAYQTSELKHGPLALICETVPTVAIVPADELTDRNVGALHEIAARRGPLVVVTHDDVDLGDLADRPE
VQRVVVPRNERELDPILLTVPLQLLAYHAALRLGHDIDKPRNLAKSVTVE

Sequences:

>Translated_610_residues
MCGIVGYVGAQQAAPILVEGLTRLEHRGYDSAGLAVLAGSGIKVAKRAGRVRDLADSLPKRFAGKVGIGHTRWATHGPAN
DVNAHPHSDAKGLVSVVHNGIIDNAAALRHRLADEGVDLVSDTDTEVLAHLVARSSADTLEGKVSQALAAIEGTYGIAVL
HVDFPDRVVVARNGSPLIVGVGEREMFVASDLAAIVRHTTTVAHLDDGELATVTATGFTTYRQDLTATAKSATVLDVDPS
SYDAGEHDSFMRKEMFEQPSAAERVLRGRLDERFGTAHLGGLNLDPRENRAIRRVKILGCGSAYYVGQMGAELVEELARI
PADAEAASEFRYRNPIIEPDTLYVAVSQSGETIDTLLAVQEIRRKGGRVVGLVNVVGSAIARECDGGIYLHAGPEVAVAS
TKALTNMFLGFALLALQLGRVRDLSIADGRRLIAGLARLPGQIEEVLAQEGALAELAGRLAEAESLFFVGRVRGYPVARE
GAQKFKEISYRHAEAYQTSELKHGPLALICETVPTVAIVPADELTDRNVGALHEIAARRGPLVVVTHDDVDLGDLADRPE
VQRVVVPRNERELDPILLTVPLQLLAYHAALRLGHDIDKPRNLAKSVTVE
>Mature_610_residues
MCGIVGYVGAQQAAPILVEGLTRLEHRGYDSAGLAVLAGSGIKVAKRAGRVRDLADSLPKRFAGKVGIGHTRWATHGPAN
DVNAHPHSDAKGLVSVVHNGIIDNAAALRHRLADEGVDLVSDTDTEVLAHLVARSSADTLEGKVSQALAAIEGTYGIAVL
HVDFPDRVVVARNGSPLIVGVGEREMFVASDLAAIVRHTTTVAHLDDGELATVTATGFTTYRQDLTATAKSATVLDVDPS
SYDAGEHDSFMRKEMFEQPSAAERVLRGRLDERFGTAHLGGLNLDPRENRAIRRVKILGCGSAYYVGQMGAELVEELARI
PADAEAASEFRYRNPIIEPDTLYVAVSQSGETIDTLLAVQEIRRKGGRVVGLVNVVGSAIARECDGGIYLHAGPEVAVAS
TKALTNMFLGFALLALQLGRVRDLSIADGRRLIAGLARLPGQIEEVLAQEGALAELAGRLAEAESLFFVGRVRGYPVARE
GAQKFKEISYRHAEAYQTSELKHGPLALICETVPTVAIVPADELTDRNVGALHEIAARRGPLVVVTHDDVDLGDLADRPE
VQRVVVPRNERELDPILLTVPLQLLAYHAALRLGHDIDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=687, Percent_Identity=35.3711790393013, Blast_Score=401, Evalue=1e-111,
Organism=Homo sapiens, GI205277386, Length=686, Percent_Identity=35.4227405247813, Blast_Score=393, Evalue=1e-109,
Organism=Homo sapiens, GI29570798, Length=288, Percent_Identity=27.0833333333333, Blast_Score=83, Evalue=8e-16,
Organism=Escherichia coli, GI1790167, Length=627, Percent_Identity=40.9888357256778, Blast_Score=423, Evalue=1e-119,
Organism=Escherichia coli, GI1788651, Length=137, Percent_Identity=33.5766423357664, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17532899, Length=433, Percent_Identity=37.6443418013857, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17532897, Length=433, Percent_Identity=37.6443418013857, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17539970, Length=432, Percent_Identity=36.5740740740741, Blast_Score=268, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI17554892, Length=221, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6322745, Length=449, Percent_Identity=37.1937639198218, Blast_Score=279, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6323731, Length=427, Percent_Identity=29.2740046838407, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6323730, Length=271, Percent_Identity=32.8413284132841, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6323958, Length=165, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357745, Length=688, Percent_Identity=35.6104651162791, Blast_Score=393, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24659598, Length=220, Percent_Identity=25.4545454545455, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24659604, Length=218, Percent_Identity=25.2293577981651, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573187, Length=273, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65286; Mature: 65286

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYVGAQQAAPILVEGLTRLEHRGYDSAGLAVLAGSGIKVAKRAGRVRDLADSLPK
CCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
RFAGKVGIGHTRWATHGPANDVNAHPHSDAKGLVSVVHNGIIDNAAALRHRLADEGVDLV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDTDTEVLAHLVARSSADTLEGKVSQALAAIEGTYGIAVLHVDFPDRVVVARNGSPLIVG
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCEEEEE
VGEREMFVASDLAAIVRHTTTVAHLDDGELATVTATGFTTYRQDLTATAKSATVLDVDPS
CCCCCHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCC
SYDAGEHDSFMRKEMFEQPSAAERVLRGRLDERFGTAHLGGLNLDPRENRAIRRVKILGC
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEEEEC
GSAYYVGQMGAELVEELARIPADAEAASEFRYRNPIIEPDTLYVAVSQSGETIDTLLAVQ
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHH
EIRRKGGRVVGLVNVVGSAIARECDGGIYLHAGPEVAVASTKALTNMFLGFALLALQLGR
HHHHCCCCEEEHHHHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHCC
VRDLSIADGRRLIAGLARLPGQIEEVLAQEGALAELAGRLAEAESLFFVGRVRGYPVARE
CCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCCCCCCHHH
GAQKFKEISYRHAEAYQTSELKHGPLALICETVPTVAIVPADELTDRNVGALHEIAARRG
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCHHCCCCCCHHHHHHHHCCC
PLVVVTHDDVDLGDLADRPEVQRVVVPRNERELDPILLTVPLQLLAYHAALRLGHDIDKP
CEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCHH
RNLAKSVTVE
HHHHHHCCCC
>Mature Secondary Structure
MCGIVGYVGAQQAAPILVEGLTRLEHRGYDSAGLAVLAGSGIKVAKRAGRVRDLADSLPK
CCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
RFAGKVGIGHTRWATHGPANDVNAHPHSDAKGLVSVVHNGIIDNAAALRHRLADEGVDLV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDTDTEVLAHLVARSSADTLEGKVSQALAAIEGTYGIAVLHVDFPDRVVVARNGSPLIVG
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCEEEEE
VGEREMFVASDLAAIVRHTTTVAHLDDGELATVTATGFTTYRQDLTATAKSATVLDVDPS
CCCCCHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCC
SYDAGEHDSFMRKEMFEQPSAAERVLRGRLDERFGTAHLGGLNLDPRENRAIRRVKILGC
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEEEEC
GSAYYVGQMGAELVEELARIPADAEAASEFRYRNPIIEPDTLYVAVSQSGETIDTLLAVQ
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHH
EIRRKGGRVVGLVNVVGSAIARECDGGIYLHAGPEVAVASTKALTNMFLGFALLALQLGR
HHHHCCCCEEEHHHHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHCC
VRDLSIADGRRLIAGLARLPGQIEEVLAQEGALAELAGRLAEAESLFFVGRVRGYPVARE
CCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCCCCCCHHH
GAQKFKEISYRHAEAYQTSELKHGPLALICETVPTVAIVPADELTDRNVGALHEIAARRG
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCHHCCCCCCHHHHHHHHCCC
PLVVVTHDDVDLGDLADRPEVQRVVVPRNERELDPILLTVPLQLLAYHAALRLGHDIDKP
CEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCHH
RNLAKSVTVE
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]