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The map label for this gene is pab [H]

Identifier: 119718747

GI number: 119718747

Start: 4789735

End: 4790298

Strand: Reverse

Name: pab [H]

Synonym: Noca_4528

Alternate gene names: 119718747

Gene position: 4790298-4789735 (Counterclockwise)

Preceding gene: 119718748

Following gene: 119718746

Centisome position: 96.08

GC content: 74.29

Gene sequence:

>564_bases
GTGGTCCCGGACGTCGTCGTGGTCGACCACCACGACTCCTACACGTGGAACCTCGTGCACCTGGTCGCGTCCGTGACCGG
TGGGCTGCCCGCGGTCGTCCAGCACGACGAGGTGTCCGCCGAGGAGGTGCTCGCGTTCAGCCACGTGGTGCTCTCGCCGG
GACCGGGCCACCCGGCCGTGCCGGCCGACTTCGCGGTGGGTGGTGAGGTGCTGCGGCGCGCGGCCCGGCCGGTGCTCGGC
GTGTGCCTGGGCATGCAGGGCCTGGTGACGACGTACGGCGGGACCGTCGGGCGGGTCGAGCCGGCGCACGGCGAGGTGGC
GCGGGTGACCCACGACGGCCGCGGGGTGTTCGCCGGGCTGCCGCCGTCGTTCCCGGTGGTCCGCTACCATTCGCTCGCGG
CGCTGGCGGTGCCCGAGGTGCTCGAGGTGACCGCGTGGGCCGGCGACGTGGTGATGGGCGTGCGGCACCGGACGTTGCCC
CTGGAGGGCGTGCAGTTCCACCCGGAGTCGATCCTCTCCGCGCACGGTGCGGCGCTGGTGGCGAACTTCCTGGGGCTGTC
GTGA

Upstream 100 bases:

>100_bases
GGCTTGGCGGCGTAGCACGGCGGGAACCCGCTCATGGGCCCGGTGAAGACTGCCCCCCAGCTTCATCGGGCCCGTCCCGT
CCCTGGAGTAGGTTGCGCGC

Downstream 100 bases:

>100_bases
GCGACCCCGCCCTCGACCCCGCCCTCGATCCCGCACGCGACCCGGTGGCGTTCTTCCGCGGCGTGGCGGCGGCGTACCCG
CGCTGCTTCTGGCTCGACGG

Product: anthranilate synthase, component II

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MVPDVVVVDHHDSYTWNLVHLVASVTGGLPAVVQHDEVSAEEVLAFSHVVLSPGPGHPAVPADFAVGGEVLRRAARPVLG
VCLGMQGLVTTYGGTVGRVEPAHGEVARVTHDGRGVFAGLPPSFPVVRYHSLAALAVPEVLEVTAWAGDVVMGVRHRTLP
LEGVQFHPESILSAHGAALVANFLGLS

Sequences:

>Translated_187_residues
MVPDVVVVDHHDSYTWNLVHLVASVTGGLPAVVQHDEVSAEEVLAFSHVVLSPGPGHPAVPADFAVGGEVLRRAARPVLG
VCLGMQGLVTTYGGTVGRVEPAHGEVARVTHDGRGVFAGLPPSFPVVRYHSLAALAVPEVLEVTAWAGDVVMGVRHRTLP
LEGVQFHPESILSAHGAALVANFLGLS
>Mature_187_residues
MVPDVVVVDHHDSYTWNLVHLVASVTGGLPAVVQHDEVSAEEVLAFSHVVLSPGPGHPAVPADFAVGGEVLRRAARPVLG
VCLGMQGLVTTYGGTVGRVEPAHGEVARVTHDGRGVFAGLPPSFPVVRYHSLAALAVPEVLEVTAWAGDVVMGVRHRTLP
LEGVQFHPESILSAHGAALVANFLGLS

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=148, Percent_Identity=30.4054054054054, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1789760, Length=188, Percent_Identity=40.9574468085106, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1787517, Length=190, Percent_Identity=38.9473684210526, Blast_Score=120, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6322638, Length=191, Percent_Identity=37.17277486911, Blast_Score=135, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=32.2274881516588, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 19484; Mature: 19484

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPDVVVVDHHDSYTWNLVHLVASVTGGLPAVVQHDEVSAEEVLAFSHVVLSPGPGHPAV
CCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHEEECCCCCCCCC
PADFAVGGEVLRRAARPVLGVCLGMQGLVTTYGGTVGRVEPAHGEVARVTHDGRGVFAGL
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEEECC
PPSFPVVRYHSLAALAVPEVLEVTAWAGDVVMGVRHRTLPLEGVQFHPESILSAHGAALV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEECHHHHHHHHHHHHH
ANFLGLS
HHHHCCC
>Mature Secondary Structure
MVPDVVVVDHHDSYTWNLVHLVASVTGGLPAVVQHDEVSAEEVLAFSHVVLSPGPGHPAV
CCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHEEECCCCCCCCC
PADFAVGGEVLRRAARPVLGVCLGMQGLVTTYGGTVGRVEPAHGEVARVTHDGRGVFAGL
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEEECC
PPSFPVVRYHSLAALAVPEVLEVTAWAGDVVMGVRHRTLPLEGVQFHPESILSAHGAALV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEECHHHHHHHHHHHHH
ANFLGLS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]