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The map label for this gene is pab [H]

Identifier: 119718746

GI number: 119718746

Start: 4788425

End: 4789738

Strand: Reverse

Name: pab [H]

Synonym: Noca_4527

Alternate gene names: 119718746

Gene position: 4789738-4788425 (Counterclockwise)

Preceding gene: 119718747

Following gene: 119718745

Centisome position: 96.07

GC content: 73.67

Gene sequence:

>1314_bases
GTGAGCGACCCCGCCCTCGACCCCGCCCTCGATCCCGCACGCGACCCGGTGGCGTTCTTCCGCGGCGTGGCGGCGGCGTA
CCCGCGCTGCTTCTGGCTCGACGGTGGCGGTGCCCGGGAGTGGTCGGGTCGTCGGTCGATGGTCGGCTGGCTGGGCGAGG
ACGACGTGTCGCTGACCTACTCCGCGGCCCGCCGGGAGGTGCGCCGGCACGTCGGCGGCAGCTGCGAGGTGGTCGGCGAC
GACGTGTTCGTCGTACTCGAGGCCGAGCTGGCCGCCGGCGCGCCCGATGACCACTGGGTGGGCTACCTCGGCTACGCCTG
CCGCCCGGACCTGCCCGCCTCGACCGGTCCCGGCCTGCCCGACGCCGTGTGGATGCGGCCGGCGGGCGTCCGGTTCTTCG
ACCACGGACTGGGCGGGCAATCCCGGAACTTCCTGGGGGAAGTTCCGGCCCAACAGTTCCGGTTTCCCCGGTTCACCGGG
GAAACCGACCCGGCCCCGCCCGCCTACGCCACCGCGTTCGAGGAGGTGCAGGAGCAGCTGCGGGCGGGGAACAGCTACGA
GGTCAACCTGACCTACCGGCTGGCGCATCGCAGCGGGGTGGACCCGGTGACGGCGTACCTGAGGCTGCGCGAGCTCAACC
CGGCGCCGTACGCCGGGTTCCTCCAGCACGATGTCCGCGACGTGCCGGACGCCCGGGCCTGGCTGCTCAGCTCCAGCCCG
GAGCGCTACGCGCTGGTGACCGCCGACCGGAGCATCGAGACCAAGCCGATCAAGGGCACCACGCTGCGCGGCGCGACCCC
CGCCGAGGACGAGGCCAGCCGGCACCGGCTCGCGACCGACTCGAAGTTCCGCGCCGAGAACCTGATGATCGTCGACCTGC
TCCGCAACGACCTCTCGATGGTGTGCCGCCCGGGGACCGTGAGCGTGCCGGCGCTGATGGACGTCGAGTCCTACGCGACC
GTGCACCAGCTGGTCAGCACCGTCCGCGGCGAGCTGCGCGACGACGTCAGCACGGTGCAGGCGCTGCGCGCGCTGTTCCC
GGCCGGCTCGATGACCGGCGCGCCGAAGCTGCGCACCATGCAGGTGATCGAGCAGGTCGAGGCCACCGAGCGCGGCCCGT
ACGCCGGCGCCTTCGGCTGGGTCTGCGCCGACGGCCGCGCCGACCTCGGCGTGGTCATCCGCAGCCTCGCCAGCACCGGC
GACGGCGCCTACCTGCTCGGCACCGGCGGCGGGATCACGGTCCGCTCCGAGGTCGCCGAGGAGTACGCCGAGTCCCGCTG
GAAGGCCGACCGGCTGCTGGCTGCGCTCGGCTGA

Upstream 100 bases:

>100_bases
TGCGGCACCGGACGTTGCCCCTGGAGGGCGTGCAGTTCCACCCGGAGTCGATCCTCTCCGCGCACGGTGCGGCGCTGGTG
GCGAACTTCCTGGGGCTGTC

Downstream 100 bases:

>100_bases
GCCGTTCCACCCGCCTGGCTACCCTCGACGGATGGAGAACCCGCACGTCATCGTGCTCTTCGGAGCCACCGGCGACCTCT
CCCGGCGCAAGCTGTTGCCG

Product: anthranilate synthase component I/chorismate-binding protein

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSDPALDPALDPARDPVAFFRGVAAAYPRCFWLDGGGAREWSGRRSMVGWLGEDDVSLTYSAARREVRRHVGGSCEVVGD
DVFVVLEAELAAGAPDDHWVGYLGYACRPDLPASTGPGLPDAVWMRPAGVRFFDHGLGGQSRNFLGEVPAQQFRFPRFTG
ETDPAPPAYATAFEEVQEQLRAGNSYEVNLTYRLAHRSGVDPVTAYLRLRELNPAPYAGFLQHDVRDVPDARAWLLSSSP
ERYALVTADRSIETKPIKGTTLRGATPAEDEASRHRLATDSKFRAENLMIVDLLRNDLSMVCRPGTVSVPALMDVESYAT
VHQLVSTVRGELRDDVSTVQALRALFPAGSMTGAPKLRTMQVIEQVEATERGPYAGAFGWVCADGRADLGVVIRSLASTG
DGAYLLGTGGGITVRSEVAEEYAESRWKADRLLAALG

Sequences:

>Translated_437_residues
MSDPALDPALDPARDPVAFFRGVAAAYPRCFWLDGGGAREWSGRRSMVGWLGEDDVSLTYSAARREVRRHVGGSCEVVGD
DVFVVLEAELAAGAPDDHWVGYLGYACRPDLPASTGPGLPDAVWMRPAGVRFFDHGLGGQSRNFLGEVPAQQFRFPRFTG
ETDPAPPAYATAFEEVQEQLRAGNSYEVNLTYRLAHRSGVDPVTAYLRLRELNPAPYAGFLQHDVRDVPDARAWLLSSSP
ERYALVTADRSIETKPIKGTTLRGATPAEDEASRHRLATDSKFRAENLMIVDLLRNDLSMVCRPGTVSVPALMDVESYAT
VHQLVSTVRGELRDDVSTVQALRALFPAGSMTGAPKLRTMQVIEQVEATERGPYAGAFGWVCADGRADLGVVIRSLASTG
DGAYLLGTGGGITVRSEVAEEYAESRWKADRLLAALG
>Mature_436_residues
SDPALDPALDPARDPVAFFRGVAAAYPRCFWLDGGGAREWSGRRSMVGWLGEDDVSLTYSAARREVRRHVGGSCEVVGDD
VFVVLEAELAAGAPDDHWVGYLGYACRPDLPASTGPGLPDAVWMRPAGVRFFDHGLGGQSRNFLGEVPAQQFRFPRFTGE
TDPAPPAYATAFEEVQEQLRAGNSYEVNLTYRLAHRSGVDPVTAYLRLRELNPAPYAGFLQHDVRDVPDARAWLLSSSPE
RYALVTADRSIETKPIKGTTLRGATPAEDEASRHRLATDSKFRAENLMIVDLLRNDLSMVCRPGTVSVPALMDVESYATV
HQLVSTVRGELRDDVSTVQALRALFPAGSMTGAPKLRTMQVIEQVEATERGPYAGAFGWVCADGRADLGVVIRSLASTGD
GAYLLGTGGGITVRSEVAEEYAESRWKADRLLAALG

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=268, Percent_Identity=39.9253731343284, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1787518, Length=289, Percent_Identity=36.3321799307958, Blast_Score=147, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320935, Length=271, Percent_Identity=34.6863468634686, Blast_Score=158, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324361, Length=302, Percent_Identity=34.1059602649007, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 47389; Mature: 47257

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPALDPALDPARDPVAFFRGVAAAYPRCFWLDGGGAREWSGRRSMVGWLGEDDVSLTY
CCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCEEECCCCCCEEEH
SAARREVRRHVGGSCEVVGDDVFVVLEAELAAGAPDDHWVGYLGYACRPDLPASTGPGLP
HHHHHHHHHHCCCCEEEECCCEEEEEEEHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCC
DAVWMRPAGVRFFDHGLGGQSRNFLGEVPAQQFRFPRFTGETDPAPPAYATAFEEVQEQL
CHHHCCCCCCHHEECCCCCCCCCHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
RAGNSYEVNLTYRLAHRSGVDPVTAYLRLRELNPAPYAGFLQHDVRDVPDARAWLLSSSP
HCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCC
ERYALVTADRSIETKPIKGTTLRGATPAEDEASRHRLATDSKFRAENLMIVDLLRNDLSM
CCEEEEEECCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHH
VCRPGTVSVPALMDVESYATVHQLVSTVRGELRDDVSTVQALRALFPAGSMTGAPKLRTM
EECCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
QVIEQVEATERGPYAGAFGWVCADGRADLGVVIRSLASTGDGAYLLGTGGGITVRSEVAE
HHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHHH
EYAESRWKADRLLAALG
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDPALDPALDPARDPVAFFRGVAAAYPRCFWLDGGGAREWSGRRSMVGWLGEDDVSLTY
CCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCEEECCCCCCEEEH
SAARREVRRHVGGSCEVVGDDVFVVLEAELAAGAPDDHWVGYLGYACRPDLPASTGPGLP
HHHHHHHHHHCCCCEEEECCCEEEEEEEHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCC
DAVWMRPAGVRFFDHGLGGQSRNFLGEVPAQQFRFPRFTGETDPAPPAYATAFEEVQEQL
CHHHCCCCCCHHEECCCCCCCCCHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
RAGNSYEVNLTYRLAHRSGVDPVTAYLRLRELNPAPYAGFLQHDVRDVPDARAWLLSSSP
HCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCC
ERYALVTADRSIETKPIKGTTLRGATPAEDEASRHRLATDSKFRAENLMIVDLLRNDLSM
CCEEEEEECCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHH
VCRPGTVSVPALMDVESYATVHQLVSTVRGELRDDVSTVQALRALFPAGSMTGAPKLRTM
EECCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
QVIEQVEATERGPYAGAFGWVCADGRADLGVVIRSLASTGDGAYLLGTGGGITVRSEVAE
HHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHHH
EYAESRWKADRLLAALG
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]