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The map label for this gene is clpB [H]

Identifier: 119718576

GI number: 119718576

Start: 4606087

End: 4608687

Strand: Reverse

Name: clpB [H]

Synonym: Noca_4357

Alternate gene names: 119718576

Gene position: 4608687-4606087 (Counterclockwise)

Preceding gene: 119718579

Following gene: 119718575

Centisome position: 92.43

GC content: 72.01

Gene sequence:

>2601_bases
ATGAGCCAGTTCGGCGCCGAGAAGTTCACCACCCGCAGCCGCGAGGCGATCGAGTCCGCCCAGCTGTCGGCGACCACGGC
CGGCAACATCCACACCGAGCCGATCCACCTGCTGGTGGCGCTGCTCCTCCAGGAGGAGGGCACCGCCGCGAACCTGGTCA
CCAAGGCCGGCGTCGACGTACCGGGCCTGGTCCGGGCCGCCGCCGCCGACCGGGACCGGCTGCCGAAGGCCTCGGGCGCC
ACCGTGCAGCAGCCGAGCGCCTCCGCGGCGCTGACCCGGGTGCTCGCGGGCGCCCTCGACCTGGCGGCCGGCATGAAGGA
CGACTACGTCGCGAGCGAGCACCTGCTGATCTCGCTGGCCACCGTCGAGAGCAGCGCCCGCACGGTGCTGACCGACGCCG
GCCTGAGCGCCGACGGCCTGCGCGAGTCGCTGACCGCGGTGCGCGGCAACCGCCGGGTGACCAGCCAGGACGCGGAGTCG
ACGTACGAGGCGCTGGAGAAGTACAGCGTCGACCTCACCACCGCCGCCGAGGAGGGCCGGCTCGACCCGGTGATCGGTCG
CGACGCCGAGATCCGGCGCGTCGTGCAGGTGCTCTCGCGGCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCG
TCGGCAAGACCGCCGTCGTCGAAGGGCTCGCCCAGCGCGTGGTCGCGGGCGACGTGCCCGACTCGCTCAAGGGCCGCCGG
GTGCTGAGCCTCGACCTGGCCGCGATGGTCGCCGGGGCGAAGTATCGCGGCGAGTTCGAGGAGCGGCTCAAGGCGGTCCT
CGAGGAGATCAAGGCCGCCGGCGGGCAGGTCATCACCTTCATCGACGAGCTGCACACCGTCGTCGGTGCGGGCGCCGGCG
GCGACTCCGCGATGGACGCCGGCAACATGCTCAAGCCGATGCTGGCCCGCGGCGAGCTGCACATGATCGGCGCGACCACC
CTCGATGAGTACCGCGAGCGGATCGAGAAGGACCCGGCGCTCGAGCGCCGCTTCCAGCAGGTGTTCGTCGGCGAGCCCAG
TGTCGAGGACACCATCCAGATCCTGCGCGGCATCCAGGAGAAGTACGAGGCCCACCACGGCGTCCGGATCACCGACGCCG
CGCTGGTCGCGGCCGCGACGCTGTCCGACCGCTACATCTCCGGGCGGCAGCTGCCCGACAAGGCCATCGACCTCATCGAC
GAGGCCGCGTCGCGGCTGCGGATGGAGATCGAGTCCTCGCCCGAGGAGATCGACCGGCTGCGGCGCGCGGTCGAGCGGCT
GAAGATGGAGGAGTTCGCGCTCGCCAAGGAGAGCGACGAGGCGTCCAAGGAGCGGCTGGCCAACCTGCGCCAGGACCTCG
CCGACCACGAGGAGGAGCTGCGCGCGCTCGAGGCCCGGTGGGAGCGGGAGAAGTCCACGCTCGAGGGCGAGGGCGAGCTG
CGCCGTCAGCTCGACCAGCTGCGCATGGAGGCCGACCGGCTGCAGCGCGAGGGCGACCTCGGCAAGGCCAGCGAGCTGCT
CTACGGCCGGATCCCCGCCCTCGAGCAGCAGATCGAGGCGGCGGGTGCTGCCGAGCGCTCCGACATCGAGCCGTTGGTCG
GCGAGGAGGTCGGGGCCGAGCAGATCGCCGAGGTCGTCGAGGCCTGGACCGGCATCCCGACCGGCCGGATGCTCGAGGGC
GAGACCGCCAAGCTGCTGCACATGGAGGACGTCATCGGCCAGCGCCTGGTCGGCCAGCGGGCCGCGGTCACGGCCGTGAG
CGACGCCGTACGCCGCTCCCGCGCCGGCATCAGCGACCCGAACCGGCCGACCGGATCCTTCCTGTTCCTCGGCCCCACCG
GCACCGGCAAGACCGAGCTCGCGAAGTCGCTCGCGGACTTCCTCTTCGACGACGAGCGGGCGATCGTGCGCATCGACATG
AGCGAGTACGGCGAGAAGCACTCGGTCGCCCGCCTGGTCGGAGCGCCCCCGGGCTACGTGGGCTACGACGAGGGCGGCCA
GCTCACCGAGGCGGTCCGTCGGCGGCCGTACTCCGTCGTCCTGCTCGACGAGGTCGAGAAGGCCCACCCGGAGGTCTTCG
ACATCCTCTTGCAGGTGCTCGACGACGGCCGGCTGACCGACGGCCAGGGCCGCACCGTCGACTTCCGCAACACGCTGCTG
ATCCTCACCAGCAACCTGGGCTCGGGCTACCTGGTCGACCCCATGCTGGACCCGGAGAAGAAGCACGAATCCGTGCTGGC
CGTGGTGCGCTCGTCGTTCAAGCCGGAGTTCCTCAACCGTCTCGACGAGATCGTGGTGTTCGACGCGCTGACGATGGACG
ACCTGGCCCACATCGTCGACCTCCAGCTCGGCCTGCTGGCCAAGCGGCTCGCGGTGCGCCGGATCACCATCGAGGTCACC
GATGCCGCGCGCCGGTGGCTGGCGGACGTCGGCTACGACCCGGCGTACGGCGCCCGTCCGCTGCGCCGGCTGATCCAGAG
CGCCATCGGCGACCCGCTGGCCAGGCTGCTCATCGGCGGCGAGGTGACCGACGGCGCGACCGTGTCGGTCGACCGCGCGG
CGGAGGGCGACGGTCTGGCGCTCGAGACGGCGCCCGCGTGA

Upstream 100 bases:

>100_bases
CCCAGAGTTGAGTGGAACAGACTCAAGTTTGGGTGCGTTGGATCAAGTGGGGCCGGCGCAGGGATGACCGGCGCAGCGAT
GCATGAGGAGAATGACGCAC

Downstream 100 bases:

>100_bases
CCGGCGTGACCCCGTGTGAGTCGGGGAGACCGGTCCGTGCGTGATCCAATGAGACCGTGAGCCGACCGACCCCGACCCGT
CCGCGCCAGGTGACCCTGGC

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 866; Mature: 865

Protein sequence:

>866_residues
MSQFGAEKFTTRSREAIESAQLSATTAGNIHTEPIHLLVALLLQEEGTAANLVTKAGVDVPGLVRAAAADRDRLPKASGA
TVQQPSASAALTRVLAGALDLAAGMKDDYVASEHLLISLATVESSARTVLTDAGLSADGLRESLTAVRGNRRVTSQDAES
TYEALEKYSVDLTTAAEEGRLDPVIGRDAEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRVVAGDVPDSLKGRR
VLSLDLAAMVAGAKYRGEFEERLKAVLEEIKAAGGQVITFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELHMIGATT
LDEYRERIEKDPALERRFQQVFVGEPSVEDTIQILRGIQEKYEAHHGVRITDAALVAAATLSDRYISGRQLPDKAIDLID
EAASRLRMEIESSPEEIDRLRRAVERLKMEEFALAKESDEASKERLANLRQDLADHEEELRALEARWEREKSTLEGEGEL
RRQLDQLRMEADRLQREGDLGKASELLYGRIPALEQQIEAAGAAERSDIEPLVGEEVGAEQIAEVVEAWTGIPTGRMLEG
ETAKLLHMEDVIGQRLVGQRAAVTAVSDAVRRSRAGISDPNRPTGSFLFLGPTGTGKTELAKSLADFLFDDERAIVRIDM
SEYGEKHSVARLVGAPPGYVGYDEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTLL
ILTSNLGSGYLVDPMLDPEKKHESVLAVVRSSFKPEFLNRLDEIVVFDALTMDDLAHIVDLQLGLLAKRLAVRRITIEVT
DAARRWLADVGYDPAYGARPLRRLIQSAIGDPLARLLIGGEVTDGATVSVDRAAEGDGLALETAPA

Sequences:

>Translated_866_residues
MSQFGAEKFTTRSREAIESAQLSATTAGNIHTEPIHLLVALLLQEEGTAANLVTKAGVDVPGLVRAAAADRDRLPKASGA
TVQQPSASAALTRVLAGALDLAAGMKDDYVASEHLLISLATVESSARTVLTDAGLSADGLRESLTAVRGNRRVTSQDAES
TYEALEKYSVDLTTAAEEGRLDPVIGRDAEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRVVAGDVPDSLKGRR
VLSLDLAAMVAGAKYRGEFEERLKAVLEEIKAAGGQVITFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELHMIGATT
LDEYRERIEKDPALERRFQQVFVGEPSVEDTIQILRGIQEKYEAHHGVRITDAALVAAATLSDRYISGRQLPDKAIDLID
EAASRLRMEIESSPEEIDRLRRAVERLKMEEFALAKESDEASKERLANLRQDLADHEEELRALEARWEREKSTLEGEGEL
RRQLDQLRMEADRLQREGDLGKASELLYGRIPALEQQIEAAGAAERSDIEPLVGEEVGAEQIAEVVEAWTGIPTGRMLEG
ETAKLLHMEDVIGQRLVGQRAAVTAVSDAVRRSRAGISDPNRPTGSFLFLGPTGTGKTELAKSLADFLFDDERAIVRIDM
SEYGEKHSVARLVGAPPGYVGYDEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTLL
ILTSNLGSGYLVDPMLDPEKKHESVLAVVRSSFKPEFLNRLDEIVVFDALTMDDLAHIVDLQLGLLAKRLAVRRITIEVT
DAARRWLADVGYDPAYGARPLRRLIQSAIGDPLARLLIGGEVTDGATVSVDRAAEGDGLALETAPA
>Mature_865_residues
SQFGAEKFTTRSREAIESAQLSATTAGNIHTEPIHLLVALLLQEEGTAANLVTKAGVDVPGLVRAAAADRDRLPKASGAT
VQQPSASAALTRVLAGALDLAAGMKDDYVASEHLLISLATVESSARTVLTDAGLSADGLRESLTAVRGNRRVTSQDAEST
YEALEKYSVDLTTAAEEGRLDPVIGRDAEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRVVAGDVPDSLKGRRV
LSLDLAAMVAGAKYRGEFEERLKAVLEEIKAAGGQVITFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELHMIGATTL
DEYRERIEKDPALERRFQQVFVGEPSVEDTIQILRGIQEKYEAHHGVRITDAALVAAATLSDRYISGRQLPDKAIDLIDE
AASRLRMEIESSPEEIDRLRRAVERLKMEEFALAKESDEASKERLANLRQDLADHEEELRALEARWEREKSTLEGEGELR
RQLDQLRMEADRLQREGDLGKASELLYGRIPALEQQIEAAGAAERSDIEPLVGEEVGAEQIAEVVEAWTGIPTGRMLEGE
TAKLLHMEDVIGQRLVGQRAAVTAVSDAVRRSRAGISDPNRPTGSFLFLGPTGTGKTELAKSLADFLFDDERAIVRIDMS
EYGEKHSVARLVGAPPGYVGYDEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTLLI
LTSNLGSGYLVDPMLDPEKKHESVLAVVRSSFKPEFLNRLDEIVVFDALTMDDLAHIVDLQLGLLAKRLAVRRITIEVTD
AARRWLADVGYDPAYGARPLRRLIQSAIGDPLARLLIGGEVTDGATVSVDRAAEGDGLALETAPA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=301, Percent_Identity=36.8770764119601, Blast_Score=201, Evalue=2e-51,
Organism=Escherichia coli, GI1788943, Length=850, Percent_Identity=57.5294117647059, Blast_Score=936, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=246, Percent_Identity=50, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6320464, Length=694, Percent_Identity=53.8904899135447, Blast_Score=752, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=865, Percent_Identity=42.3121387283237, Blast_Score=673, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 93962; Mature: 93830

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFGAEKFTTRSREAIESAQLSATTAGNIHTEPIHLLVALLLQEEGTAANLVTKAGVDV
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCC
PGLVRAAAADRDRLPKASGATVQQPSASAALTRVLAGALDLAAGMKDDYVASEHLLISLA
CHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEE
TVESSARTVLTDAGLSADGLRESLTAVRGNRRVTSQDAESTYEALEKYSVDLTTAAEEGR
HHCCCCHHEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCC
LDPVIGRDAEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRVVAGDVPDSLKGRR
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCE
VLSLDLAAMVAGAKYRGEFEERLKAVLEEIKAAGGQVITFIDELHTVVGAGAGGDSAMDA
EEEHHHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHCC
GNMLKPMLARGELHMIGATTLDEYRERIEKDPALERRFQQVFVGEPSVEDTIQILRGIQE
HHHHHHHHHCCCEEEEECHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KYEAHHGVRITDAALVAAATLSDRYISGRQLPDKAIDLIDEAASRLRMEIESSPEEIDRL
HHHHHCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RRAVERLKMEEFALAKESDEASKERLANLRQDLADHEEELRALEARWEREKSTLEGEGEL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RRQLDQLRMEADRLQREGDLGKASELLYGRIPALEQQIEAAGAAERSDIEPLVGEEVGAE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHCCCCCHH
QIAEVVEAWTGIPTGRMLEGETAKLLHMEDVIGQRLVGQRAAVTAVSDAVRRSRAGISDP
HHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NRPTGSFLFLGPTGTGKTELAKSLADFLFDDERAIVRIDMSEYGEKHSVARLVGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHCCCHHHHHHHHCCCCCCC
GYDEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTLL
CCCCCCHHHHHHHHCCCEEEEEHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
ILTSNLGSGYLVDPMLDPEKKHESVLAVVRSSFKPEFLNRLDEIVVFDALTMDDLAHIVD
EEEECCCCCCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LQLGLLAKRLAVRRITIEVTDAARRWLADVGYDPAYGARPLRRLIQSAIGDPLARLLIGG
HHHHHHHHHHHHHHEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCC
EVTDGATVSVDRAAEGDGLALETAPA
CCCCCCEEEECCCCCCCCEEECCCCC
>Mature Secondary Structure 
SQFGAEKFTTRSREAIESAQLSATTAGNIHTEPIHLLVALLLQEEGTAANLVTKAGVDV
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCC
PGLVRAAAADRDRLPKASGATVQQPSASAALTRVLAGALDLAAGMKDDYVASEHLLISLA
CHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEE
TVESSARTVLTDAGLSADGLRESLTAVRGNRRVTSQDAESTYEALEKYSVDLTTAAEEGR
HHCCCCHHEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCC
LDPVIGRDAEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRVVAGDVPDSLKGRR
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCE
VLSLDLAAMVAGAKYRGEFEERLKAVLEEIKAAGGQVITFIDELHTVVGAGAGGDSAMDA
EEEHHHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHCC
GNMLKPMLARGELHMIGATTLDEYRERIEKDPALERRFQQVFVGEPSVEDTIQILRGIQE
HHHHHHHHHCCCEEEEECHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KYEAHHGVRITDAALVAAATLSDRYISGRQLPDKAIDLIDEAASRLRMEIESSPEEIDRL
HHHHHCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RRAVERLKMEEFALAKESDEASKERLANLRQDLADHEEELRALEARWEREKSTLEGEGEL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RRQLDQLRMEADRLQREGDLGKASELLYGRIPALEQQIEAAGAAERSDIEPLVGEEVGAE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHCCCCCHH
QIAEVVEAWTGIPTGRMLEGETAKLLHMEDVIGQRLVGQRAAVTAVSDAVRRSRAGISDP
HHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NRPTGSFLFLGPTGTGKTELAKSLADFLFDDERAIVRIDMSEYGEKHSVARLVGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHCCCHHHHHHHHCCCCCCC
GYDEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTLL
CCCCCCHHHHHHHHCCCEEEEEHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
ILTSNLGSGYLVDPMLDPEKKHESVLAVVRSSFKPEFLNRLDEIVVFDALTMDDLAHIVD
EEEECCCCCCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LQLGLLAKRLAVRRITIEVTDAARRWLADVGYDPAYGARPLRRLIQSAIGDPLARLLIGG
HHHHHHHHHHHHHHEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCC
EVTDGATVSVDRAAEGDGLALETAPA
CCCCCCEEEECCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12839748 [H]