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The map label for this gene is dxs [C]

Identifier: 119718440

GI number: 119718440

Start: 4462048

End: 4462971

Strand: Reverse

Name: dxs [C]

Synonym: Noca_4221

Alternate gene names: 119718440

Gene position: 4462971-4462048 (Counterclockwise)

Preceding gene: 119718441

Following gene: 119718439

Centisome position: 89.51

GC content: 62.88

Gene sequence:

>924_bases
GTGAGGACGCGGTTCTTCGCTGACCTGCTCGAGGCCGCGCGACTCAATCCCGACATAGTCTTGATTACGGGTGACCTCGG
GTTCGGCGTTGTCGAGCCCTTTGTCGCTGCTTGTCCCAGCCAATTCGTCAATGCAGGTGTTGCCGAGCAGAACATGACCG
GCATGGCGGCGGGGATGGCCATGGCTGGAGCGAAGGCATTCACCTACTCGATCGCGAACTTTCCCACGCTGAGGTGTCTC
GAGCAGATCCGGAACGACGTTGCCTACCACGGGGCGGACGTCGTCGTGGTTAGCGTGGGCGGAGGCCTAGCTTACGGGGC
GCTGGGCATGTCCCATCACGCCACCGAGGACCTGGCCATCATGCGTTCGATCCCCGGTCTCGCGGTCGCCGCTCCCGGAG
ACCCGGAGGAGACCAGCGCCGTCTTGGAGAACCTACTCGTAGGAGGCGGGCCGGCGTATCTTCGCCTCGGCAAGGCTGGC
GAACGAACCGTCCACGCTACGCGACCGCAGCTGAACCGAGGGCAGTCCATTACCCTGAAATCGGGTGCCGACGTTGCTCT
CGTCTCCACGGGTGCAATGCTTCCGACCGTAATGGATGCAGCAGAGGAGCTCGATGACCTCGGTGTTTCATCGACAGTGG
TTTCATCACCTTGGATCGCACCGTTTGACGAGGCAACGATCCGAAGGCTCGCGGCGACCCACCGGTTGCTCGTCACGATC
GAGGAGCACTCGATCACGGGCGGCCTCGGTGGTGCAACTGCAGAAGTCCTTGCCGAGACAGGCGGTGTGTGCCCGCTCAT
GCGGATCGGAGTATTACCCCGGTTCAGCTCGGTCGTCGGCGACCAAGAGTACCTGCGTGGTGTGCACGGGCTGACACGGC
AAGCCATCACCGAACGAGCGATCAAGCGACTGGAGGACCTCTGA

Upstream 100 bases:

>100_bases
TCAAGGGCAAAGGCGTGTCGTTCATGGAGAACAACGTGCTCTGGCACTACCGGCCGCCGTCTGAGGATGAGTTGGCGTTG
GCGTTGACGGAGATCGCGAC

Downstream 100 bases:

>100_bases
TGGGATGGCGGGTCAAGTTTATCGACTTTCCGCTGCAATGGGAGCAGCAGCGAGCGCACCTCCTTCCGGTCATCGACGAC
ACACTGGCGCGGGGCGACGT

Product: transketolase subunit B

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRTRFFADLLEAARLNPDIVLITGDLGFGVVEPFVAACPSQFVNAGVAEQNMTGMAAGMAMAGAKAFTYSIANFPTLRCL
EQIRNDVAYHGADVVVVSVGGGLAYGALGMSHHATEDLAIMRSIPGLAVAAPGDPEETSAVLENLLVGGGPAYLRLGKAG
ERTVHATRPQLNRGQSITLKSGADVALVSTGAMLPTVMDAAEELDDLGVSSTVVSSPWIAPFDEATIRRLAATHRLLVTI
EEHSITGGLGGATAEVLAETGGVCPLMRIGVLPRFSSVVGDQEYLRGVHGLTRQAITERAIKRLEDL

Sequences:

>Translated_307_residues
MRTRFFADLLEAARLNPDIVLITGDLGFGVVEPFVAACPSQFVNAGVAEQNMTGMAAGMAMAGAKAFTYSIANFPTLRCL
EQIRNDVAYHGADVVVVSVGGGLAYGALGMSHHATEDLAIMRSIPGLAVAAPGDPEETSAVLENLLVGGGPAYLRLGKAG
ERTVHATRPQLNRGQSITLKSGADVALVSTGAMLPTVMDAAEELDDLGVSSTVVSSPWIAPFDEATIRRLAATHRLLVTI
EEHSITGGLGGATAEVLAETGGVCPLMRIGVLPRFSSVVGDQEYLRGVHGLTRQAITERAIKRLEDL
>Mature_307_residues
MRTRFFADLLEAARLNPDIVLITGDLGFGVVEPFVAACPSQFVNAGVAEQNMTGMAAGMAMAGAKAFTYSIANFPTLRCL
EQIRNDVAYHGADVVVVSVGGGLAYGALGMSHHATEDLAIMRSIPGLAVAAPGDPEETSAVLENLLVGGGPAYLRLGKAG
ERTVHATRPQLNRGQSITLKSGADVALVSTGAMLPTVMDAAEELDDLGVSSTVVSSPWIAPFDEATIRRLAATHRLLVTI
EEHSITGGLGGATAEVLAETGGVCPLMRIGVLPRFSSVVGDQEYLRGVHGLTRQAITERAIKRLEDL

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=248, Percent_Identity=28.2258064516129, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI205277463, Length=286, Percent_Identity=28.6713286713287, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4507521, Length=286, Percent_Identity=28.6713286713287, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI225637459, Length=242, Percent_Identity=27.6859504132231, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI225637463, Length=244, Percent_Identity=27.4590163934426, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI225637461, Length=242, Percent_Identity=27.6859504132231, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1786622, Length=294, Percent_Identity=31.2925170068027, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17539652, Length=266, Percent_Identity=31.203007518797, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24645119, Length=241, Percent_Identity=28.2157676348548, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45551847, Length=241, Percent_Identity=28.2157676348548, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550715, Length=241, Percent_Identity=28.2157676348548, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666278, Length=265, Percent_Identity=27.5471698113208, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 32090; Mature: 32090

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRFFADLLEAARLNPDIVLITGDLGFGVVEPFVAACPSQFVNAGVAEQNMTGMAAGMA
CCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHH
MAGAKAFTYSIANFPTLRCLEQIRNDVAYHGADVVVVSVGGGLAYGALGMSHHATEDLAI
HHCCHHHEEEHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCHHHHHH
MRSIPGLAVAAPGDPEETSAVLENLLVGGGPAYLRLGKAGERTVHATRPQLNRGQSITLK
HHCCCCCEEECCCCCHHHHHHHHHHHCCCCHHEEEECCCCCCCEECCCCCCCCCCEEEEE
SGADVALVSTGAMLPTVMDAAEELDDLGVSSTVVSSPWIAPFDEATIRRLAATHRLLVTI
CCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHCEEEEEE
EEHSITGGLGGATAEVLAETGGVCPLMRIGVLPRFSSVVGDQEYLRGVHGLTRQAITERA
ECCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IKRLEDL
HHHHHCC
>Mature Secondary Structure
MRTRFFADLLEAARLNPDIVLITGDLGFGVVEPFVAACPSQFVNAGVAEQNMTGMAAGMA
CCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHH
MAGAKAFTYSIANFPTLRCLEQIRNDVAYHGADVVVVSVGGGLAYGALGMSHHATEDLAI
HHCCHHHEEEHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCHHHHHH
MRSIPGLAVAAPGDPEETSAVLENLLVGGGPAYLRLGKAGERTVHATRPQLNRGQSITLK
HHCCCCCEEECCCCCHHHHHHHHHHHCCCCHHEEEECCCCCCCEECCCCCCCCCCEEEEE
SGADVALVSTGAMLPTVMDAAEELDDLGVSSTVVSSPWIAPFDEATIRRLAATHRLLVTI
CCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHCEEEEEE
EEHSITGGLGGATAEVLAETGGVCPLMRIGVLPRFSSVVGDQEYLRGVHGLTRQAITERA
ECCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IKRLEDL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]