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The map label for this gene is ubiE [C]

Identifier: 119718435

GI number: 119718435

Start: 4457350

End: 4458183

Strand: Reverse

Name: ubiE [C]

Synonym: Noca_4216

Alternate gene names: 119718435

Gene position: 4458183-4457350 (Counterclockwise)

Preceding gene: 119718436

Following gene: 119718423

Centisome position: 89.42

GC content: 55.04

Gene sequence:

>834_bases
ATGCCAGATGAAATCTGGTTGTCGTCCTTGGACGAGCGGAAGCGTCGGGAACTGGAATTCCATGACCGGGACCGGGACCG
GACTGCCGAGTCGGAGCTTGATCAGGATACCTACGAAAAATTCTATGGAAACCGGAAATACTATTCTGCGACGGCTGACT
CTCGGTCGTACGTCAATGATTGGATCAGCTCCAATGCGAAGGGCAGGGTGTTTCTGGACTATGCATGTGGCAACGGCGCC
CAGGCTATTCTTGCGGCGAAAAGTGGAGCAGCATTGGCAATCGGGATCGACATCAGCGCGGTTTCGGTTGAGAATGCTAC
CGCAGATGCTCACGAGGCAGGCGTCTCAGAAAACGCGAGGTTCATTCAGGCAGACGCCGAAAGGACGTTGCTTCCCGATA
GCTCCATCGATGTTGTGATCTGCTCTGGGATGCTCCACCATCTGGATTTGTCTTTCGCATTTCCGGAGCTTAGGCGCATC
CTTAAGCCAGGCGGCAAGATTCTTGCGGTCGAAGCGCTAGACTACAATCCGGCCATCAAGGCTTACAGGAAGCTCACGCC
TCAGATGCGAACGGAATGGGAGAAGGCGCATATCCTGAGTTTCAAGGATGTGCGGTTCGCCCGACGCTTTTTCGAGGTCG
GCGAAGTGCGCTATTGGCATCTCCTGGGAATATTGTCACCGCACGTTCCCGCGCTGGCTGGTTTCCTGGAGCGGGCTGAT
CGTCGCTTGAGCAAGATTCCGCTGTTCCAACGGATGGCTTGGATCTTCACCTTCGAATTAATCAAGCCAGTCGCCGCGGA
GGGCCAAGTCCCTATTGCGCCCATGGTTAAATAG

Upstream 100 bases:

>100_bases
GCTGAAAGCCAACGACGGACTTGTGTGAGCCCAACCAAGGAGAAGATCCGTGCCTCAGGACCTGCAGACGCTACTTGAAC
ACCTGTCAAAGATCGCAGCG

Downstream 100 bases:

>100_bases
AAGCCGGGCCGAGATCAGAAGCTGTCGTGTTATAAATCCAGCGCGCCAGCTCCACGCCGTTTAGTTGTGCGTTGAATTCT
CGCTTCACGATCTCGCGTCC

Product: type 11 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase UbiE/COQ5 Family; Methyltransferase Domain Family

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MPDEIWLSSLDERKRRELEFHDRDRDRTAESELDQDTYEKFYGNRKYYSATADSRSYVNDWISSNAKGRVFLDYACGNGA
QAILAAKSGAALAIGIDISAVSVENATADAHEAGVSENARFIQADAERTLLPDSSIDVVICSGMLHHLDLSFAFPELRRI
LKPGGKILAVEALDYNPAIKAYRKLTPQMRTEWEKAHILSFKDVRFARRFFEVGEVRYWHLLGILSPHVPALAGFLERAD
RRLSKIPLFQRMAWIFTFELIKPVAAEGQVPIAPMVK

Sequences:

>Translated_277_residues
MPDEIWLSSLDERKRRELEFHDRDRDRTAESELDQDTYEKFYGNRKYYSATADSRSYVNDWISSNAKGRVFLDYACGNGA
QAILAAKSGAALAIGIDISAVSVENATADAHEAGVSENARFIQADAERTLLPDSSIDVVICSGMLHHLDLSFAFPELRRI
LKPGGKILAVEALDYNPAIKAYRKLTPQMRTEWEKAHILSFKDVRFARRFFEVGEVRYWHLLGILSPHVPALAGFLERAD
RRLSKIPLFQRMAWIFTFELIKPVAAEGQVPIAPMVK
>Mature_276_residues
PDEIWLSSLDERKRRELEFHDRDRDRTAESELDQDTYEKFYGNRKYYSATADSRSYVNDWISSNAKGRVFLDYACGNGAQ
AILAAKSGAALAIGIDISAVSVENATADAHEAGVSENARFIQADAERTLLPDSSIDVVICSGMLHHLDLSFAFPELRRIL
KPGGKILAVEALDYNPAIKAYRKLTPQMRTEWEKAHILSFKDVRFARRFFEVGEVRYWHLLGILSPHVPALAGFLERADR
RLSKIPLFQRMAWIFTFELIKPVAAEGQVPIAPMVK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31334; Mature: 31203

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDEIWLSSLDERKRRELEFHDRDRDRTAESELDQDTYEKFYGNRKYYSATADSRSYVND
CCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHCCCCEEEEECCCCHHHHHH
WISSNAKGRVFLDYACGNGAQAILAAKSGAALAIGIDISAVSVENATADAHEAGVSENAR
HHCCCCCCEEEEEEECCCCCEEEEEECCCCEEEEEEEEEEEEECCCCCHHHHCCCCCCCE
FIQADAERTLLPDSSIDVVICSGMLHHLDLSFAFPELRRILKPGGKILAVEALDYNPAIK
EEECCCCCEECCCCCCCEEEECHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCCHHHH
AYRKLTPQMRTEWEKAHILSFKDVRFARRFFEVGEVRYWHLLGILSPHVPALAGFLERAD
HHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
RRLSKIPLFQRMAWIFTFELIKPVAAEGQVPIAPMVK
HHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PDEIWLSSLDERKRRELEFHDRDRDRTAESELDQDTYEKFYGNRKYYSATADSRSYVND
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHCCCCEEEEECCCCHHHHHH
WISSNAKGRVFLDYACGNGAQAILAAKSGAALAIGIDISAVSVENATADAHEAGVSENAR
HHCCCCCCEEEEEEECCCCCEEEEEECCCCEEEEEEEEEEEEECCCCCHHHHCCCCCCCE
FIQADAERTLLPDSSIDVVICSGMLHHLDLSFAFPELRRILKPGGKILAVEALDYNPAIK
EEECCCCCEECCCCCCCEEEECHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCCHHHH
AYRKLTPQMRTEWEKAHILSFKDVRFARRFFEVGEVRYWHLLGILSPHVPALAGFLERAD
HHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
RRLSKIPLFQRMAWIFTFELIKPVAAEGQVPIAPMVK
HHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA