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The map label for this gene is manC [H]

Identifier: 119718405

GI number: 119718405

Start: 4425779

End: 4426168

Strand: Reverse

Name: manC [H]

Synonym: Noca_4186

Alternate gene names: 119718405

Gene position: 4426168-4425779 (Counterclockwise)

Preceding gene: 119718406

Following gene: 119718403

Centisome position: 88.77

GC content: 68.46

Gene sequence:

>390_bases
ATGGGTGAGTCGGACGTACGTCCGTGGGGATCGTGGGAGGTCCTCGACGAAGGTCTCGGCTACAAGGTCAAGCGGCTGGT
CGTGAGGCCGCGCCAGCGGCTCTCCTACCAGACCCACTCCTACCGTGCGGAGCACTGGGTGATCGTCAGCGGCCGAGCGA
CCTGTGTGATCAACGGCGTCGTCCGCAAGGCCCGGCCCGGTGACTATGTCGATGTCCCGGTCGGGGCCGCGCACCGGCTG
ATGAACGAGGAGCAGGAGCCGCTCGTCGTCATCGAGGTGCAGCGCGGGCTGTACACCGGCGAGGACGACATCGTCCGGCT
CGAGGACGACTACGGGCGCAGCGAGGTCGTCATCGCGACGCCGGGGCGGTTGCTCGACGCGCTGGCCTGA

Upstream 100 bases:

>100_bases
AGTACTTCCTCCAGATTCCCTCAAGGTCGGCCCGACCTACGGTCTCGATCTCTCGGGCCGTCCTAGCGTGGGCTCACCGA
TCGACGACTGGGGGGTAGTC

Downstream 100 bases:

>100_bases
AGCGGCCTGCCTGAGGCGGGTCTCGGTAGGCTCGCTGGCGCTCGCTACTCGCGCCGGGTTGCTCGCCGGCGCGGGTGACT
CCGGCTCCTTGCCCTGCCTT

Product: mannose-6-phosphate isomerase, type II

Products: NA

Alternate protein names: GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MGESDVRPWGSWEVLDEGLGYKVKRLVVRPRQRLSYQTHSYRAEHWVIVSGRATCVINGVVRKARPGDYVDVPVGAAHRL
MNEEQEPLVVIEVQRGLYTGEDDIVRLEDDYGRSEVVIATPGRLLDALA

Sequences:

>Translated_129_residues
MGESDVRPWGSWEVLDEGLGYKVKRLVVRPRQRLSYQTHSYRAEHWVIVSGRATCVINGVVRKARPGDYVDVPVGAAHRL
MNEEQEPLVVIEVQRGLYTGEDDIVRLEDDYGRSEVVIATPGRLLDALA
>Mature_128_residues
GESDVRPWGSWEVLDEGLGYKVKRLVVRPRQRLSYQTHSYRAEHWVIVSGRATCVINGVVRKARPGDYVDVPVGAAHRLM
NEEQEPLVVIEVQRGLYTGEDDIVRLEDDYGRSEVVIATPGRLLDALA

Specific function: Involved in the biosynthesis of the capsular polysaccharide colanic acid [H]

COG id: COG0662

COG function: function code G; Mannose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=107, Percent_Identity=45.7943925233645, Blast_Score=102, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 14558; Mature: 14427

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGESDVRPWGSWEVLDEGLGYKVKRLVVRPRQRLSYQTHSYRAEHWVIVSGRATCVINGV
CCCCCCCCCCCHHHHHCCCCCEEHHHHHCCHHHCCCCCCCCCCCEEEEECCCCEEEEECC
VRKARPGDYVDVPVGAAHRLMNEEQEPLVVIEVQRGLYTGEDDIVRLEDDYGRSEVVIAT
HHCCCCCCEEECCCCHHHHHCCCCCCCEEEEEECCCEECCCCCEEEEECCCCCCEEEEEC
PGRLLDALA
CHHHHHHCC
>Mature Secondary Structure 
GESDVRPWGSWEVLDEGLGYKVKRLVVRPRQRLSYQTHSYRAEHWVIVSGRATCVINGV
CCCCCCCCCCHHHHHCCCCCEEHHHHHCCHHHCCCCCCCCCCCEEEEECCCCEEEEECC
VRKARPGDYVDVPVGAAHRLMNEEQEPLVVIEVQRGLYTGEDDIVRLEDDYGRSEVVIAT
HHCCCCCCEEECCCCHHHHHCCCCCCCEEEEEECCCEECCCCCEEEEECCCCCCEEEEEC
PGRLLDALA
CHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1712067; 11677609 [H]