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The map label for this gene is epsC [H]

Identifier: 119718403

GI number: 119718403

Start: 4422049

End: 4423881

Strand: Reverse

Name: epsC [H]

Synonym: Noca_4184

Alternate gene names: 119718403

Gene position: 4423881-4422049 (Counterclockwise)

Preceding gene: 119718405

Following gene: 119718402

Centisome position: 88.73

GC content: 70.81

Gene sequence:

>1833_bases
GTGAGCGACTTGGTCGCGCGTATGAGGCGGCGCCGCGCGCCGCTCGCCATCGCGTTCGACGTGTGTGCCTGGTTGCTCGG
CTACGCGGCGTTCGCCTGGCTTCGGCTCGACAGTGACGCCTCGAGCGTGCCGTGGCCGGAGGTGCTCGCCTTCGCGACCG
TGACTGCGACGCTGTACGTGGCACTGGCGGCGCCCCTCCGGCTCCACCAGGGCCGCGCCCGCACCGCGAGCCTGGAGGAG
ATGGTGCTCCTCGGGATGCTGATGGGCGGCGTCGGTGGCGGCGTCTTCCTGGTGAACCTGTTCGGCCAGTGGATCCCCCG
CAGCATCCCGGCCGGGGCGACCTGCGGTGCGCTCGTGCTCGCCGCGTGGGCGCGGGCGAGCTGGCGGACCCTGCAGGAGC
GCGACGAGCGCACCGGCGCCGGTGAGGACACCGAGCGGACGCTGGTGATGGGCGCGGGTGAGGCCGGCCGCGAGCTGATC
ACCTCGATGCAGCGCGACCCGCTGCGGCGCTACCTGCCGGTCGGACTGCTCGACGACGATCCCTACAAGCGGCACCGCCG
GCTGCGCGGCGTACCCGTCCTCGGGACCAGCTGCGACCTGGAGAAGGAGGTCGCGCGCACCGGGGCGACCATGGTCGTGA
TCGCGATCCCCAGCGCCAGTGCCGAGACGGTCAACCGGCTCCGGCTCACGGCTCTGGACGCCCATGTGTCGGTCAAGGTG
TTGCCGTCCACCACGCAGCTCCTCACCGACAGCGTCGGCATCCGCGACCTGCGGGACATCAACATCACCGACGTACTCGG
CCGCAACCAGCTGGACACGGACGTCGCCTCGATCGCCGGCTACCTGGCCGGGCGGAAGGTGCTGGTCACCGGTGCCGGCG
GCTCCATCGGCTCCGAGCTGTGCCGCCAGATCTACCGCTACCAGCCGGCCGAGCTGATGATGCTCGACCGTGACGAGTCC
GCGCTCCACTCGGTCCAGCTCTCGATCCACGGCCGTGCCCTGCTGGACTCGGACGACGTCATCCTGTGCGACATCCGGGA
CGAGAAGGCGGTGCGAACCATCTTCGCGAACCGTCGCCCCGACGTCGTCTTCCACGCCGCCGCGCTCAAGCACCTGCCGA
TGCTCGAGCAGTACCCGGCCGAGGCCGTGAAGACCAACGTGATCGGCACCCGCACGGTTCTCGATGCCGCAGACCTCGTC
GGTGTCGACAGGTTCGTGAACATCTCCACGGACAAGGCGGCGAACCCGTCCAGCGTCCTGGGCTACTCCAAGCGGGTCGC
CGAGCGGATCACAGCCGCCCAGGCGCGCGAGGCTTCCGGGACGTATCTCTCGGTGCGCTTCGGGAACGTGCTCGGCAGCC
GTGGCTCGGTGCTGGCGGCGTTCGCCCGGCAGATCGCCGCCGGTGGGCCGATCACGGTCACCCACCCGGACGTCAGCCGC
TTCTTCATGACGATCGAGGAGGCCTGCCAGCTGGTCATCCAGGCGGCTGCGATCGGCGGGCCGGGGGAGGCGCTCGTCCT
CGACATGGGCGAGCCGGTGAAGATCGTGGACGTCGCCGAGCAGCTGATCGAGCAGGCCGGCACGCCGGTGCCGATCGAAT
ACACCGGGCTGCGCGAGGGCGAGAAGTTGCACGAGGAGCTCTTCGGCGAAGGCGAGCCGTGCGACGTCCGGCCGCGGCAC
CCGCTGGTCTCGCACGTGCCGGTGCCACCGATCACCGACGGCGAGGTCCTGGGCCTCACCCTCGTCGGCGAGCCTGACGA
CGTGCGGCAGGCGCTGCACGACGCGTGCCTGGTGTCGATCGAGGCCGACGACCCGTCCTCGCTGCGGAACTGA

Upstream 100 bases:

>100_bases
GTGGACTAGTCCAGTTGCCGAAAACAGGTCCGAAGCCACGCAGGAACGACCACACTCGACGCCGGGTGAGGGGACATCCG
AGATCACCGGGGGACATGAC

Downstream 100 bases:

>100_bases
AGCCCGGCGGGGTCTCGTCGGCTCGCTCGCTGGTCGGCGGTGGGTTGCGGTAGCGGGAACGAGATGACGTGGTCGCCGTC
CTGCCCGGGTGTGGGGATCT

Product: polysaccharide biosynthesis protein CapD

Products: dTDP-4-dehydro-6-deoxy-D-glucose; H2O [C]

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MSDLVARMRRRRAPLAIAFDVCAWLLGYAAFAWLRLDSDASSVPWPEVLAFATVTATLYVALAAPLRLHQGRARTASLEE
MVLLGMLMGGVGGGVFLVNLFGQWIPRSIPAGATCGALVLAAWARASWRTLQERDERTGAGEDTERTLVMGAGEAGRELI
TSMQRDPLRRYLPVGLLDDDPYKRHRRLRGVPVLGTSCDLEKEVARTGATMVVIAIPSASAETVNRLRLTALDAHVSVKV
LPSTTQLLTDSVGIRDLRDINITDVLGRNQLDTDVASIAGYLAGRKVLVTGAGGSIGSELCRQIYRYQPAELMMLDRDES
ALHSVQLSIHGRALLDSDDVILCDIRDEKAVRTIFANRRPDVVFHAAALKHLPMLEQYPAEAVKTNVIGTRTVLDAADLV
GVDRFVNISTDKAANPSSVLGYSKRVAERITAAQAREASGTYLSVRFGNVLGSRGSVLAAFARQIAAGGPITVTHPDVSR
FFMTIEEACQLVIQAAAIGGPGEALVLDMGEPVKIVDVAEQLIEQAGTPVPIEYTGLREGEKLHEELFGEGEPCDVRPRH
PLVSHVPVPPITDGEVLGLTLVGEPDDVRQALHDACLVSIEADDPSSLRN

Sequences:

>Translated_610_residues
MSDLVARMRRRRAPLAIAFDVCAWLLGYAAFAWLRLDSDASSVPWPEVLAFATVTATLYVALAAPLRLHQGRARTASLEE
MVLLGMLMGGVGGGVFLVNLFGQWIPRSIPAGATCGALVLAAWARASWRTLQERDERTGAGEDTERTLVMGAGEAGRELI
TSMQRDPLRRYLPVGLLDDDPYKRHRRLRGVPVLGTSCDLEKEVARTGATMVVIAIPSASAETVNRLRLTALDAHVSVKV
LPSTTQLLTDSVGIRDLRDINITDVLGRNQLDTDVASIAGYLAGRKVLVTGAGGSIGSELCRQIYRYQPAELMMLDRDES
ALHSVQLSIHGRALLDSDDVILCDIRDEKAVRTIFANRRPDVVFHAAALKHLPMLEQYPAEAVKTNVIGTRTVLDAADLV
GVDRFVNISTDKAANPSSVLGYSKRVAERITAAQAREASGTYLSVRFGNVLGSRGSVLAAFARQIAAGGPITVTHPDVSR
FFMTIEEACQLVIQAAAIGGPGEALVLDMGEPVKIVDVAEQLIEQAGTPVPIEYTGLREGEKLHEELFGEGEPCDVRPRH
PLVSHVPVPPITDGEVLGLTLVGEPDDVRQALHDACLVSIEADDPSSLRN
>Mature_609_residues
SDLVARMRRRRAPLAIAFDVCAWLLGYAAFAWLRLDSDASSVPWPEVLAFATVTATLYVALAAPLRLHQGRARTASLEEM
VLLGMLMGGVGGGVFLVNLFGQWIPRSIPAGATCGALVLAAWARASWRTLQERDERTGAGEDTERTLVMGAGEAGRELIT
SMQRDPLRRYLPVGLLDDDPYKRHRRLRGVPVLGTSCDLEKEVARTGATMVVIAIPSASAETVNRLRLTALDAHVSVKVL
PSTTQLLTDSVGIRDLRDINITDVLGRNQLDTDVASIAGYLAGRKVLVTGAGGSIGSELCRQIYRYQPAELMMLDRDESA
LHSVQLSIHGRALLDSDDVILCDIRDEKAVRTIFANRRPDVVFHAAALKHLPMLEQYPAEAVKTNVIGTRTVLDAADLVG
VDRFVNISTDKAANPSSVLGYSKRVAERITAAQAREASGTYLSVRFGNVLGSRGSVLAAFARQIAAGGPITVTHPDVSRF
FMTIEEACQLVIQAAAIGGPGEALVLDMGEPVKIVDVAEQLIEQAGTPVPIEYTGLREGEKLHEELFGEGEPCDVRPRHP
LVSHVPVPPITDGEVLGLTLVGEPDDVRQALHDACLVSIEADDPSSLRN

Specific function: Involved in biofilm formation [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: 4.2.1.46 [C]

Molecular weight: Translated: 65768; Mature: 65637

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLVARMRRRRAPLAIAFDVCAWLLGYAAFAWLRLDSDASSVPWPEVLAFATVTATLYV
CCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHH
ALAAPLRLHQGRARTASLEEMVLLGMLMGGVGGGVFLVNLFGQWIPRSIPAGATCGALVL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AAWARASWRTLQERDERTGAGEDTERTLVMGAGEAGRELITSMQRDPLRRYLPVGLLDDD
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCHHHHHCCCCCCCCC
PYKRHRRLRGVPVLGTSCDLEKEVARTGATMVVIAIPSASAETVNRLRLTALDAHVSVKV
HHHHHHHHCCCCEECCCCCHHHHHHHCCCEEEEEEECCCCHHHHHHEEEEEEECEEEEEE
LPSTTQLLTDSVGIRDLRDINITDVLGRNQLDTDVASIAGYLAGRKVLVTGAGGSIGSEL
CCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHH
CRQIYRYQPAELMMLDRDESALHSVQLSIHGRALLDSDDVILCDIRDEKAVRTIFANRRP
HHHHHHCCCCCEEEEECCCHHHHEEEEEECCEEEECCCCEEEEECCCCHHHHHHHCCCCC
DVVFHAAALKHLPMLEQYPAEAVKTNVIGTRTVLDAADLVGVDRFVNISTDKAANPSSVL
CEEEEHHHHHHCCCHHHCCHHHHHHCCCCHHHHHHHHHHHCCHHEEEECCCCCCCCHHHH
GYSKRVAERITAAQAREASGTYLSVRFGNVLGSRGSVLAAFARQIAAGGPITVTHPDVSR
HHHHHHHHHHHHHHHHCCCCCEEEEEECCHHCCCCHHHHHHHHHHHCCCCEEEECCCHHH
FFMTIEEACQLVIQAAAIGGPGEALVLDMGEPVKIVDVAEQLIEQAGTPVPIEYTGLREG
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCCCH
EKLHEELFGEGEPCDVRPRHPLVSHVPVPPITDGEVLGLTLVGEPDDVRQALHDACLVSI
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHEEEEE
EADDPSSLRN
ECCCCHHCCC
>Mature Secondary Structure 
SDLVARMRRRRAPLAIAFDVCAWLLGYAAFAWLRLDSDASSVPWPEVLAFATVTATLYV
CHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHH
ALAAPLRLHQGRARTASLEEMVLLGMLMGGVGGGVFLVNLFGQWIPRSIPAGATCGALVL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AAWARASWRTLQERDERTGAGEDTERTLVMGAGEAGRELITSMQRDPLRRYLPVGLLDDD
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCHHHHHCCCCCCCCC
PYKRHRRLRGVPVLGTSCDLEKEVARTGATMVVIAIPSASAETVNRLRLTALDAHVSVKV
HHHHHHHHCCCCEECCCCCHHHHHHHCCCEEEEEEECCCCHHHHHHEEEEEEECEEEEEE
LPSTTQLLTDSVGIRDLRDINITDVLGRNQLDTDVASIAGYLAGRKVLVTGAGGSIGSEL
CCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHH
CRQIYRYQPAELMMLDRDESALHSVQLSIHGRALLDSDDVILCDIRDEKAVRTIFANRRP
HHHHHHCCCCCEEEEECCCHHHHEEEEEECCEEEECCCCEEEEECCCCHHHHHHHCCCCC
DVVFHAAALKHLPMLEQYPAEAVKTNVIGTRTVLDAADLVGVDRFVNISTDKAANPSSVL
CEEEEHHHHHHCCCHHHCCHHHHHHCCCCHHHHHHHHHHHCCHHEEEECCCCCCCCHHHH
GYSKRVAERITAAQAREASGTYLSVRFGNVLGSRGSVLAAFARQIAAGGPITVTHPDVSR
HHHHHHHHHHHHHHHHCCCCCEEEEEECCHHCCCCHHHHHHHHHHHCCCCEEEECCCHHH
FFMTIEEACQLVIQAAAIGGPGEALVLDMGEPVKIVDVAEQLIEQAGTPVPIEYTGLREG
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCCCH
EKLHEELFGEGEPCDVRPRHPLVSHVPVPPITDGEVLGLTLVGEPDDVRQALHDACLVSI
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHEEEEE
EADDPSSLRN
ECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.019 {NAD+}} 0.034 {dTDPglucose}} [C]

Substrates: dTDPglucose [C]

Specific reaction: dTDPglucose --> dTDP-4-dehydro-6-deoxy-D-glucose + H2O [C]

General reaction: Elimination (of H2O C-O bond cleavage [C]

Inhibitor: TDP; TTP [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969506; 9384377 [H]