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The map label for this gene is tadA [H]

Identifier: 119718363

GI number: 119718363

Start: 4378177

End: 4378641

Strand: Reverse

Name: tadA [H]

Synonym: Noca_4144

Alternate gene names: 119718363

Gene position: 4378641-4378177 (Counterclockwise)

Preceding gene: 119718364

Following gene: 119718361

Centisome position: 87.82

GC content: 68.17

Gene sequence:

>465_bases
ATGACCGACGAAGAGATGCTCGTCCTGGCCGTCGAGGAGGCCCGCCGCGGACTCGCGGAGGGCGGGATCCCGATCGGCGC
CGTCCTCATCCACGACGGCGAGGTCTTGGGTGGCGGCCACAACCGTCGGGTCCAGCTCGGCAGCGCGATCCGGCATGGTG
AGACCGACTGCCTGGAGAACATCGGCCGACTGCCGGCGAGCGTCTACGCGCGCTCGACGATGGTGACGACCCTGTCGCCC
TGCGACATGTGCACCGGCGCGATCTTGCTCTACGGCATCCCGCGCGTGGTCGTCGGCGAGAACCGCAACTTCCTCGGCGG
TGAGGAGCTGCTGGCCTCCCGAGGGGTGGAGGTGGTCGTTCTGGACGACCTGGGCTGTGTCGAGATGATGGCCACCTTCA
TCGCCGAGCACCCGACGCTGTGGAACGAGGACATCGGGGTCGAGGACGACTCGTCGGTCTCGTAG

Upstream 100 bases:

>100_bases
CGCGATCGGGGGACGCAGTGTGCGCTACCCGGGCTCCTACCTCAAGGCCTACCGCCGTGGGTGACCTCGCCCGCCCCGTC
ACTTCCAGAAGGAGACGTCA

Downstream 100 bases:

>100_bases
CCCGCAGCGGGTCGGGCTTCACACGTTGCGACGATACTGGCCGCCCACCTCGCAGAACGCGTCGGTCACCTGGCCGAGCG
AGCAGACGCGGGCCGCGTCC

Product: cytosine deaminase

Products: uracil; NH3

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTDEEMLVLAVEEARRGLAEGGIPIGAVLIHDGEVLGGGHNRRVQLGSAIRHGETDCLENIGRLPASVYARSTMVTTLSP
CDMCTGAILLYGIPRVVVGENRNFLGGEELLASRGVEVVVLDDLGCVEMMATFIAEHPTLWNEDIGVEDDSSVS

Sequences:

>Translated_154_residues
MTDEEMLVLAVEEARRGLAEGGIPIGAVLIHDGEVLGGGHNRRVQLGSAIRHGETDCLENIGRLPASVYARSTMVTTLSP
CDMCTGAILLYGIPRVVVGENRNFLGGEELLASRGVEVVVLDDLGCVEMMATFIAEHPTLWNEDIGVEDDSSVS
>Mature_153_residues
TDEEMLVLAVEEARRGLAEGGIPIGAVLIHDGEVLGGGHNRRVQLGSAIRHGETDCLENIGRLPASVYARSTMVTTLSPC
DMCTGAILLYGIPRVVVGENRNFLGGEELLASRGVEVVVLDDLGCVEMMATFIAEHPTLWNEDIGVEDDSSVS

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=111, Percent_Identity=30.6306306306306, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325319, Length=147, Percent_Identity=58.5034013605442, Blast_Score=165, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.1

Molecular weight: Translated: 16420; Mature: 16289

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDEEMLVLAVEEARRGLAEGGIPIGAVLIHDGEVLGGGHNRRVQLGSAIRHGETDCLEN
CCCCCEEEEEHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCEEEECHHHHCCCHHHHHH
IGRLPASVYARSTMVTTLSPCDMCTGAILLYGIPRVVVGENRNFLGGEELLASRGVEVVV
HHCCCHHHHHHHHHEEECCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCEEEE
LDDLGCVEMMATFIAEHPTLWNEDIGVEDDSSVS
ECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDEEMLVLAVEEARRGLAEGGIPIGAVLIHDGEVLGGGHNRRVQLGSAIRHGETDCLEN
CCCCEEEEEHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCEEEECHHHHCCCHHHHHH
IGRLPASVYARSTMVTTLSPCDMCTGAILLYGIPRVVVGENRNFLGGEELLASRGVEVVV
HHCCCHHHHHHHHHEEECCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCEEEE
LDDLGCVEMMATFIAEHPTLWNEDIGVEDDSSVS
ECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytosine; H2O

Specific reaction: cytosine + H2O = uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]