Click here to switch to the map view.

The map label for this gene is livK [C]

Identifier: 119718346

GI number: 119718346

Start: 4358432

End: 4359634

Strand: Reverse

Name: livK [C]

Synonym: Noca_4127

Alternate gene names: 119718346

Gene position: 4359634-4358432 (Counterclockwise)

Preceding gene: 119718347

Following gene: 119718336

Centisome position: 87.44

GC content: 70.24

Gene sequence:

>1203_bases
ATGACCCGTTTCAAGACGGTGCGGCGCGCGCTGGTCGCGGCGATCGCTCTCGGATCGATGCTGAGTGTCGCCGCGTGCGG
CAACGGCGAGGCCGGCAGCGCGTCCGGCACTGACAGCGGCAGCGCCGATGACCCCCTGCGGGTCGGCCTGCTGTTCTCCC
TGACCGGCCCCGCGGCGCCGTACGGCATCAGCGAGCGCAACGGCGCCCGCGTCGTGCTCGACCAGATCAACGAGGACGGC
GGGATCAACGGCCAGCAGATCGAGATCTTCGAGGCCGACGACAAGACCGACCCGACCGAGGCGGCCCAGCAGGCCCGCAA
GCTGATCACCCAGGACAAGGTCGACGTGATCATCGGCACCACCGCAGGCGGCAACACGCTCGCCTACGCACCGATCGCGG
CCGGCCTGAAGACGCCGATCCTGGCCACCAACGGCACGATCTCGGTGACCGACAAGGCCAACGACTTCTGGCCCTGGATC
TTCCGGTCCGCGCCGAGCGACCTGGTCACCATGCAGGCGATGTTCGACCAGGTGGTGGCCGAGGGGAAGACCCGGATCGG
CATCTTCGCCGAGCAGTCGGCGTACGGCGACGCCAGCGTCGCGTACCTCGAGGAGCAGGTCGAGAAGGCCGGGCTCGAGA
TCGTCGCGGAGACCAGCGCCGCGGTCACGGACACCGACTTCACCGCGCAGGCGACCAAGCTGCGCAACGCCGACCCGGAC
GTCGTCCTGCTCGTCACCGGTGCGACCGCGCTCGGCGTCGGCATCGCGCGGGCGGTCCGCCAGGGTGGCTCCGACGTGGA
CATGTGGGGCGGCATCGGCCTGGCCCAGCAGGGCTTCATCGACGGCGCCGGCCCCGACGCCGAGGGTGTCCACATGGTCG
CGATGAACAACTGGAACGACCCGTCCGAGGACGAGCAGCAGCTCAAGGACCTGCTCGAGGCGGCCGGGTTCGAGGCCACG
TCGTTCGAGGCCGCGGGTGCCAACGGCGCTCAGGTGGTGGCCGCCGGCGCCGAGAAGGTCGAGGGCGAGATCACCGGGGA
GAAGCTCCGCGACGCGATGGCGACCGTGTGCGACCTCAACACCTACGCGATCGGCGAGTCGGTCTGCTACACCGAGGACG
AGCGGGACGGGATGGGCACCGACGCCCTGGCCCTCCTGGTCGTCGAGGACGGTGCGTTCGCGACGTACGACCCCAACGCC
TGA

Upstream 100 bases:

>100_bases
GTCTTGGCGCCACTACTTGATATTGACGTCAAGTTCATTCTATCGTGTGTGGCCGAGACCACATGACCCGATGCATGTGC
TGGACCCCTGTGAGGATGAG

Downstream 100 bases:

>100_bases
CCACCTCCAGTCAGGACGAGGCCCCGGCGGTGCCACCGCCGGGGCCTCGGCGCGTCCGGGGCCGGCCTTTGCCGTCAGCG
ATGCTGCCGCGCTGGGGCCG

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTRFKTVRRALVAAIALGSMLSVAACGNGEAGSASGTDSGSADDPLRVGLLFSLTGPAAPYGISERNGARVVLDQINEDG
GINGQQIEIFEADDKTDPTEAAQQARKLITQDKVDVIIGTTAGGNTLAYAPIAAGLKTPILATNGTISVTDKANDFWPWI
FRSAPSDLVTMQAMFDQVVAEGKTRIGIFAEQSAYGDASVAYLEEQVEKAGLEIVAETSAAVTDTDFTAQATKLRNADPD
VVLLVTGATALGVGIARAVRQGGSDVDMWGGIGLAQQGFIDGAGPDAEGVHMVAMNNWNDPSEDEQQLKDLLEAAGFEAT
SFEAAGANGAQVVAAGAEKVEGEITGEKLRDAMATVCDLNTYAIGESVCYTEDERDGMGTDALALLVVEDGAFATYDPNA

Sequences:

>Translated_400_residues
MTRFKTVRRALVAAIALGSMLSVAACGNGEAGSASGTDSGSADDPLRVGLLFSLTGPAAPYGISERNGARVVLDQINEDG
GINGQQIEIFEADDKTDPTEAAQQARKLITQDKVDVIIGTTAGGNTLAYAPIAAGLKTPILATNGTISVTDKANDFWPWI
FRSAPSDLVTMQAMFDQVVAEGKTRIGIFAEQSAYGDASVAYLEEQVEKAGLEIVAETSAAVTDTDFTAQATKLRNADPD
VVLLVTGATALGVGIARAVRQGGSDVDMWGGIGLAQQGFIDGAGPDAEGVHMVAMNNWNDPSEDEQQLKDLLEAAGFEAT
SFEAAGANGAQVVAAGAEKVEGEITGEKLRDAMATVCDLNTYAIGESVCYTEDERDGMGTDALALLVVEDGAFATYDPNA
>Mature_399_residues
TRFKTVRRALVAAIALGSMLSVAACGNGEAGSASGTDSGSADDPLRVGLLFSLTGPAAPYGISERNGARVVLDQINEDGG
INGQQIEIFEADDKTDPTEAAQQARKLITQDKVDVIIGTTAGGNTLAYAPIAAGLKTPILATNGTISVTDKANDFWPWIF
RSAPSDLVTMQAMFDQVVAEGKTRIGIFAEQSAYGDASVAYLEEQVEKAGLEIVAETSAAVTDTDFTAQATKLRNADPDV
VLLVTGATALGVGIARAVRQGGSDVDMWGGIGLAQQGFIDGAGPDAEGVHMVAMNNWNDPSEDEQQLKDLLEAAGFEATS
FEAAGANGAQVVAAGAEKVEGEITGEKLRDAMATVCDLNTYAIGESVCYTEDERDGMGTDALALLVVEDGAFATYDPNA

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI48994941, Length=288, Percent_Identity=23.2638888888889, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789867, Length=281, Percent_Identity=24.9110320284698, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 41455; Mature: 41324

Theoretical pI: Translated: 3.91; Mature: 3.91

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFKTVRRALVAAIALGSMLSVAACGNGEAGSASGTDSGSADDPLRVGLLFSLTGPAAP
CCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCC
YGISERNGARVVLDQINEDGGINGQQIEIFEADDKTDPTEAAQQARKLITQDKVDVIIGT
CCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEE
TAGGNTLAYAPIAAGLKTPILATNGTISVTDKANDFWPWIFRSAPSDLVTMQAMFDQVVA
CCCCCEEEECHHHCCCCCCEEECCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHH
EGKTRIGIFAEQSAYGDASVAYLEEQVEKAGLEIVAETSAAVTDTDFTAQATKLRNADPD
CCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCEEECCCCCHHHHHHCCCCCC
VVLLVTGATALGVGIARAVRQGGSDVDMWGGIGLAQQGFIDGAGPDAEGVHMVAMNNWND
EEEEEECCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCC
PSEDEQQLKDLLEAAGFEATSFEAAGANGAQVVAAGAEKVEGEITGEKLRDAMATVCDLN
CCHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEECCHHHHCCCCCHHHHHHHHHHHHCCC
TYAIGESVCYTEDERDGMGTDALALLVVEDGAFATYDPNA
CEECCCEEEECCCCCCCCCCCEEEEEEEECCCEEECCCCC
>Mature Secondary Structure 
TRFKTVRRALVAAIALGSMLSVAACGNGEAGSASGTDSGSADDPLRVGLLFSLTGPAAP
CHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCC
YGISERNGARVVLDQINEDGGINGQQIEIFEADDKTDPTEAAQQARKLITQDKVDVIIGT
CCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEE
TAGGNTLAYAPIAAGLKTPILATNGTISVTDKANDFWPWIFRSAPSDLVTMQAMFDQVVA
CCCCCEEEECHHHCCCCCCEEECCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHH
EGKTRIGIFAEQSAYGDASVAYLEEQVEKAGLEIVAETSAAVTDTDFTAQATKLRNADPD
CCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCEEECCCCCHHHHHHCCCCCC
VVLLVTGATALGVGIARAVRQGGSDVDMWGGIGLAQQGFIDGAGPDAEGVHMVAMNNWND
EEEEEECCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCC
PSEDEQQLKDLLEAAGFEATSFEAAGANGAQVVAAGAEKVEGEITGEKLRDAMATVCDLN
CCHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEECCHHHHCCCCCHHHHHHHHHHHHCCC
TYAIGESVCYTEDERDGMGTDALALLVVEDGAFATYDPNA
CEECCCEEEECCCCCCCCCCCEEEEEEEECCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]