Click here to switch to the map view.

The map label for this gene is paaG [C]

Identifier: 119718326

GI number: 119718326

Start: 4340083

End: 4340874

Strand: Reverse

Name: paaG [C]

Synonym: Noca_4107

Alternate gene names: 119718326

Gene position: 4340874-4340083 (Counterclockwise)

Preceding gene: 119718327

Following gene: 119718325

Centisome position: 87.06

GC content: 71.97

Gene sequence:

>792_bases
ATGAGCGAGCCGATGGTGCTCAATGACGTCGTTGGTGCCGTGCAGGTGATCTCGCTGAACCGGCCCGACCGGCTCAACGC
GATGACCAAGGGGCTGGTCGACGAGCTGTTGCCGGTCCTCGAGACGGCGGCCGCCGATCCAGCGGTCCGCTGCGTGGTGC
TCACCGGGGTGGGGCGCGGTTTCTGCGCCGGCGGTGACCTCGGCGAGATCGGCGACCTCGCCGTGGGCGTCGACGTGGCG
CGCGAGGAAGCCGACCTGCGCCGGCTGCACCGCTCGAGCCAGCTGCTGCACGAGATGGGGAAGCCCACGATCGCCGCGGT
GAACGGGCCGTGCGCCGGCGCCGGCCTCTCGTGGGCCTGCGCCTGCGACCTGCGCCTGGCCGCGAGCTCGGCGGTGTTCC
GGTCGTCGTTCGTGTCGGCCGGACTGACCGGAGACTTCGGCTCCAGCTGGACCCTGCCGCGGATCGTCGGCGCGGGTATG
GCCCGCGAGCTGTGTCTGCTCAACCGGAAGTTCGACGCCGCGGAGGCCCTCCGGATCGGGTTGGTCTCCGAGGTGATGCC
CGATGAGCTCTTCCGCGACCGGGTGCTGGAGGTCGCCACGCAGCTCGCCGCCCAGGCGCCGATCGCGATGGCAGGCATGA
AGGCGAACCTGAACGACGCCGAGCTGGTCGGCTTCGGCGAGCTGCTCGACCGCGAGGCCGCCCGCCAGGCCGCCGCCACC
GCGTCCTCGGACTGTGTGGAGGCGGCCACGGCGTTCCTCGAGCGCCGGGAGCCGGTCTTTGTCGGTGACTGA

Upstream 100 bases:

>100_bases
GCCGCGCTGGTCGCGGAGGTCCGGGTGGCGCCAGGCGACCAGGTCGCGGCGGGGGACGTGCTGGTGGTGCTGGCACCGTG
ACGATGAAGAGGGATGGACG

Downstream 100 bases:

>100_bases
GCCGGGGCCCGGGCGCCCCGGCGACGTGAGCCGGCCGGCTGTGGCCGGCGCGGCCTGACGGCCCGGGCACCGCCCGGGCG
GTCGCGGAGCCGCTCGACGA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSEPMVLNDVVGAVQVISLNRPDRLNAMTKGLVDELLPVLETAAADPAVRCVVLTGVGRGFCAGGDLGEIGDLAVGVDVA
REEADLRRLHRSSQLLHEMGKPTIAAVNGPCAGAGLSWACACDLRLAASSAVFRSSFVSAGLTGDFGSSWTLPRIVGAGM
ARELCLLNRKFDAAEALRIGLVSEVMPDELFRDRVLEVATQLAAQAPIAMAGMKANLNDAELVGFGELLDREAARQAAAT
ASSDCVEAATAFLERREPVFVGD

Sequences:

>Translated_263_residues
MSEPMVLNDVVGAVQVISLNRPDRLNAMTKGLVDELLPVLETAAADPAVRCVVLTGVGRGFCAGGDLGEIGDLAVGVDVA
REEADLRRLHRSSQLLHEMGKPTIAAVNGPCAGAGLSWACACDLRLAASSAVFRSSFVSAGLTGDFGSSWTLPRIVGAGM
ARELCLLNRKFDAAEALRIGLVSEVMPDELFRDRVLEVATQLAAQAPIAMAGMKANLNDAELVGFGELLDREAARQAAAT
ASSDCVEAATAFLERREPVFVGD
>Mature_262_residues
SEPMVLNDVVGAVQVISLNRPDRLNAMTKGLVDELLPVLETAAADPAVRCVVLTGVGRGFCAGGDLGEIGDLAVGVDVAR
EEADLRRLHRSSQLLHEMGKPTIAAVNGPCAGAGLSWACACDLRLAASSAVFRSSFVSAGLTGDFGSSWTLPRIVGAGMA
RELCLLNRKFDAAEALRIGLVSEVMPDELFRDRVLEVATQLAAQAPIAMAGMKANLNDAELVGFGELLDREAARQAAATA
SSDCVEAATAFLERREPVFVGD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=250, Percent_Identity=34, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI194097323, Length=253, Percent_Identity=33.201581027668, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI260274832, Length=243, Percent_Identity=27.9835390946502, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI45643119, Length=243, Percent_Identity=27.9835390946502, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI260275230, Length=243, Percent_Identity=27.9835390946502, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI25453481, Length=207, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI51538573, Length=207, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI4757966, Length=214, Percent_Identity=29.9065420560748, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI51538581, Length=214, Percent_Identity=29.9065420560748, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4502327, Length=259, Percent_Identity=30.8880308880309, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4757968, Length=207, Percent_Identity=29.951690821256, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI49355787, Length=207, Percent_Identity=29.951690821256, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI221136756, Length=257, Percent_Identity=27.2373540856031, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI221136753, Length=257, Percent_Identity=27.2373540856031, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI221307494, Length=216, Percent_Identity=30.0925925925926, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI116235487, Length=212, Percent_Identity=28.7735849056604, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI37594469, Length=190, Percent_Identity=28.4210526315789, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI37594471, Length=190, Percent_Identity=28.4210526315789, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20127408, Length=207, Percent_Identity=28.5024154589372, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI31542718, Length=257, Percent_Identity=24.9027237354086, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787660, Length=266, Percent_Identity=35.7142857142857, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787659, Length=251, Percent_Identity=33.4661354581673, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI87082183, Length=267, Percent_Identity=29.2134831460674, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788597, Length=247, Percent_Identity=30.3643724696356, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI221142681, Length=272, Percent_Identity=29.7794117647059, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788682, Length=209, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=257, Percent_Identity=31.9066147859922, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17536985, Length=259, Percent_Identity=28.5714285714286, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=31.4516129032258, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17554946, Length=245, Percent_Identity=30.6122448979592, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17535521, Length=252, Percent_Identity=29.3650793650794, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17549921, Length=211, Percent_Identity=30.8056872037915, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17540714, Length=208, Percent_Identity=29.3269230769231, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560910, Length=249, Percent_Identity=26.5060240963855, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25144160, Length=186, Percent_Identity=26.8817204301075, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144157, Length=186, Percent_Identity=26.8817204301075, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540306, Length=244, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=193, Percent_Identity=26.9430051813472, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920382, Length=258, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI20129971, Length=251, Percent_Identity=30.6772908366534, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24653477, Length=251, Percent_Identity=30.6772908366534, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24653139, Length=257, Percent_Identity=30.7392996108949, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24654903, Length=176, Percent_Identity=29.5454545454545, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357171, Length=197, Percent_Identity=31.9796954314721, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24650670, Length=182, Percent_Identity=29.6703296703297, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27537; Mature: 27406

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPMVLNDVVGAVQVISLNRPDRLNAMTKGLVDELLPVLETAAADPAVRCVVLTGVGRG
CCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
FCAGGDLGEIGDLAVGVDVAREEADLRRLHRSSQLLHEMGKPTIAAVNGPCAGAGLSWAC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEE
ACDLRLAASSAVFRSSFVSAGLTGDFGSSWTLPRIVGAGMARELCLLNRKFDAAEALRIG
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LVSEVMPDELFRDRVLEVATQLAAQAPIAMAGMKANLNDAELVGFGELLDREAARQAAAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHH
ASSDCVEAATAFLERREPVFVGD
CCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SEPMVLNDVVGAVQVISLNRPDRLNAMTKGLVDELLPVLETAAADPAVRCVVLTGVGRG
CCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
FCAGGDLGEIGDLAVGVDVAREEADLRRLHRSSQLLHEMGKPTIAAVNGPCAGAGLSWAC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEE
ACDLRLAASSAVFRSSFVSAGLTGDFGSSWTLPRIVGAGMARELCLLNRKFDAAEALRIG
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LVSEVMPDELFRDRVLEVATQLAAQAPIAMAGMKANLNDAELVGFGELLDREAARQAAAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHH
ASSDCVEAATAFLERREPVFVGD
CCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA