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The map label for this gene is mtaD [H]

Identifier: 119718325

GI number: 119718325

Start: 4338230

End: 4339627

Strand: Reverse

Name: mtaD [H]

Synonym: Noca_4106

Alternate gene names: 119718325

Gene position: 4339627-4338230 (Counterclockwise)

Preceding gene: 119718326

Following gene: 119718324

Centisome position: 87.04

GC content: 68.88

Gene sequence:

>1398_bases
ATGCCCAGCACCCTTCTCACCCATGCCGTGGTCATCACTATGGACGCAGACCGCCGGGTCTTCTCCGACGGCTACGTTCA
GATGGAGGACGGGCTCGTCCGGGACGTCGGGCCCGCGTCCGAGGCGCCGACGGGCCGCCCCTGGACACAGGTCCGCGATC
TCGGTGGGCGGCACGTCGTCATGCCCGGCCTGGTCAACACGCACGACCACTTGAGCCTGAGCGTCGTCCGCGGGGGCCTG
GACGAGCTCGACCGGCTCGAGATGGGCACGAAGATGTTCGACGCCCTCCGGGTCATCGACGGTCCCGCCTCCTACGACGG
GGCACGGTGCTCGATCGCCGAGCTGCTGCTCGCGGGTGTCACCACGACCGCCTGCGACGAGTTCGGTCACCGGGACCGGC
CAGCAGGTGTGCTGCAGGCGTGCCGGGAGATGGGCATCTGCACCCTCTTCGGGCGCGCCACGATGGATAGCACGGACGAG
ACCGTGAACTCGCAGACCATCCCGCTCGACTTCCGGGAGGCGCCCGAGGACGCCATCGCCCGCGTCGAGGAGCTCAGACG
TGACTACGACTCCCCACTCATCGCGGTGCATCCGTCCGCGGTCTCCACCATGCGCGTCTCGACCGAGATGATGCGCGCGC
TGAGCGAGTACGCCGCCGCGGAGCGGCTCATGCTCATGCTCCATATGGGAGCGGATCGGGACGAGCAGGCGGAATCCCAG
CGGCGCTACGGCAAACTGCTCGTCGAGTACATGGCGGACATCGGTGCTCTCGAGTCCCAAGTGCTGCTCGCGCACGCGAC
CTGGACCGAGGAGAGCGAGATCCCCTTGCTCGCCCAGCACGACGTCGCGGTCGCCCACTGTCCGGAAAGCAACGCCCACG
AGGGCGACCCGATCAGCCGGGTGGCGTCCTGGCTCGCGGCGGGGCTACGGGTCGGGCTCGGCAGTGACGGCGCCAACACG
GGCAACTCCCAGAATCTGTGGGAGACCGCCAAGCTCGCGGTCTACCAGCAGAAGACCCGGGAGCGAGACGGTCTCTACGG
TTCGGCTGAGCTCGGCCTGGAGCTGCTGACGCTGCACGGCGCCCGGGCGCTCTACCAGGAACACCGGCTGGGTGCGCTGG
TTCCGGGCCGGGCCGCGGACGTCATCTGCCTCGACATCGACCGCCCCAGCCTCGCCCCGCGGGGAACGATCTTGTCCAAC
CTGGTCTATGCCAATGACCGCTCGGCCGTCCGACACGTGTATGTCGCAGGCGAGGAGCGAGTTCGTGACGGGGAGCTGCT
CGGGTACGACGTGGAGGAGCTCGCGGCCCGGGCCACGTCGGCTTCGGCGACGGTGATGGACGCCAGTGGATTCGGTCGTG
ACGTCATGGCCAAGTCGCGGTTCCGCTGGGTGCGCTGA

Upstream 100 bases:

>100_bases
CCCAGGTCCGTGACCCCGCTCGGCTCGTTGCGGTAAACAGTGTTGCGATGAGTGGAACAGAACCTCGTCTGCTCGCCCGC
CGCCTCAGGAGCCGACAGCC

Downstream 100 bases:

>100_bases
GTGCCGCCGCCTACCCGGTCGAGACGCGCCCGATCGCGCCGCGGAGCTTCGCGGTCGGAGTGTGTTGACACGTCGGCCCG
GCGGTGCGAAAGTTCTCTCA

Product: amidohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MPSTLLTHAVVITMDADRRVFSDGYVQMEDGLVRDVGPASEAPTGRPWTQVRDLGGRHVVMPGLVNTHDHLSLSVVRGGL
DELDRLEMGTKMFDALRVIDGPASYDGARCSIAELLLAGVTTTACDEFGHRDRPAGVLQACREMGICTLFGRATMDSTDE
TVNSQTIPLDFREAPEDAIARVEELRRDYDSPLIAVHPSAVSTMRVSTEMMRALSEYAAAERLMLMLHMGADRDEQAESQ
RRYGKLLVEYMADIGALESQVLLAHATWTEESEIPLLAQHDVAVAHCPESNAHEGDPISRVASWLAAGLRVGLGSDGANT
GNSQNLWETAKLAVYQQKTRERDGLYGSAELGLELLTLHGARALYQEHRLGALVPGRAADVICLDIDRPSLAPRGTILSN
LVYANDRSAVRHVYVAGEERVRDGELLGYDVEELAARATSASATVMDASGFGRDVMAKSRFRWVR

Sequences:

>Translated_465_residues
MPSTLLTHAVVITMDADRRVFSDGYVQMEDGLVRDVGPASEAPTGRPWTQVRDLGGRHVVMPGLVNTHDHLSLSVVRGGL
DELDRLEMGTKMFDALRVIDGPASYDGARCSIAELLLAGVTTTACDEFGHRDRPAGVLQACREMGICTLFGRATMDSTDE
TVNSQTIPLDFREAPEDAIARVEELRRDYDSPLIAVHPSAVSTMRVSTEMMRALSEYAAAERLMLMLHMGADRDEQAESQ
RRYGKLLVEYMADIGALESQVLLAHATWTEESEIPLLAQHDVAVAHCPESNAHEGDPISRVASWLAAGLRVGLGSDGANT
GNSQNLWETAKLAVYQQKTRERDGLYGSAELGLELLTLHGARALYQEHRLGALVPGRAADVICLDIDRPSLAPRGTILSN
LVYANDRSAVRHVYVAGEERVRDGELLGYDVEELAARATSASATVMDASGFGRDVMAKSRFRWVR
>Mature_464_residues
PSTLLTHAVVITMDADRRVFSDGYVQMEDGLVRDVGPASEAPTGRPWTQVRDLGGRHVVMPGLVNTHDHLSLSVVRGGLD
ELDRLEMGTKMFDALRVIDGPASYDGARCSIAELLLAGVTTTACDEFGHRDRPAGVLQACREMGICTLFGRATMDSTDET
VNSQTIPLDFREAPEDAIARVEELRRDYDSPLIAVHPSAVSTMRVSTEMMRALSEYAAAERLMLMLHMGADRDEQAESQR
RYGKLLVEYMADIGALESQVLLAHATWTEESEIPLLAQHDVAVAHCPESNAHEGDPISRVASWLAAGLRVGLGSDGANTG
NSQNLWETAKLAVYQQKTRERDGLYGSAELGLELLTLHGARALYQEHRLGALVPGRAADVICLDIDRPSLAPRGTILSNL
VYANDRSAVRHVYVAGEERVRDGELLGYDVEELAARATSASATVMDASGFGRDVMAKSRFRWVR

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=399, Percent_Identity=24.3107769423559, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789249, Length=410, Percent_Identity=25.3658536585366, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082177, Length=445, Percent_Identity=24.2696629213483, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17540282, Length=392, Percent_Identity=25.2551020408163, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319963, Length=341, Percent_Identity=25.8064516129032, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24643849, Length=462, Percent_Identity=22.2943722943723, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 50755; Mature: 50624

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTLLTHAVVITMDADRRVFSDGYVQMEDGLVRDVGPASEAPTGRPWTQVRDLGGRHVV
CCCHHEEEEEEEEECCCCEECCCCCEEECCCCEECCCCCCCCCCCCCHHHHHHCCCCEEE
MPGLVNTHDHLSLSVVRGGLDELDRLEMGTKMFDALRVIDGPASYDGARCSIAELLLAGV
ECCCCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
TTTACDEFGHRDRPAGVLQACREMGICTLFGRATMDSTDETVNSQTIPLDFREAPEDAIA
HHHHHHHCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHCCHHHHH
RVEELRRDYDSPLIAVHPSAVSTMRVSTEMMRALSEYAAAERLMLMLHMGADRDEQAESQ
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RRYGKLLVEYMADIGALESQVLLAHATWTEESEIPLLAQHDVAVAHCPESNAHEGDPISR
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCEEEEECCCCCCCCCCHHHH
VASWLAAGLRVGLGSDGANTGNSQNLWETAKLAVYQQKTRERDGLYGSAELGLELLTLHG
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCEEHHHHHH
ARALYQEHRLGALVPGRAADVICLDIDRPSLAPRGTILSNLVYANDRSAVRHVYVAGEER
HHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHEECCCCHHEEEEEECCCCC
VRDGELLGYDVEELAARATSASATVMDASGFGRDVMAKSRFRWVR
CCCCCEECCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
PSTLLTHAVVITMDADRRVFSDGYVQMEDGLVRDVGPASEAPTGRPWTQVRDLGGRHVV
CCHHEEEEEEEEECCCCEECCCCCEEECCCCEECCCCCCCCCCCCCHHHHHHCCCCEEE
MPGLVNTHDHLSLSVVRGGLDELDRLEMGTKMFDALRVIDGPASYDGARCSIAELLLAGV
ECCCCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
TTTACDEFGHRDRPAGVLQACREMGICTLFGRATMDSTDETVNSQTIPLDFREAPEDAIA
HHHHHHHCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHCCHHHHH
RVEELRRDYDSPLIAVHPSAVSTMRVSTEMMRALSEYAAAERLMLMLHMGADRDEQAESQ
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RRYGKLLVEYMADIGALESQVLLAHATWTEESEIPLLAQHDVAVAHCPESNAHEGDPISR
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCEEEEECCCCCCCCCCHHHH
VASWLAAGLRVGLGSDGANTGNSQNLWETAKLAVYQQKTRERDGLYGSAELGLELLTLHG
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCEEHHHHHH
ARALYQEHRLGALVPGRAADVICLDIDRPSLAPRGTILSNLVYANDRSAVRHVYVAGEER
HHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHEECCCCHHEEEEEECCCCC
VRDGELLGYDVEELAARATSASATVMDASGFGRDVMAKSRFRWVR
CCCCCEECCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA