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The map label for this gene is citE [H]

Identifier: 119718298

GI number: 119718298

Start: 4306928

End: 4307779

Strand: Reverse

Name: citE [H]

Synonym: Noca_4079

Alternate gene names: 119718298

Gene position: 4307779-4306928 (Counterclockwise)

Preceding gene: 119718300

Following gene: 119718297

Centisome position: 86.4

GC content: 75.0

Gene sequence:

>852_bases
GTGATCCCTCGGTCGTACCTCTACGTTCCCGGCGACGATGCCGCGAAGCTGGAGAAGGCGACCTCGCGAGGCGCCGACGC
GCTGATCGTCGACCTGGAGGACGCGGTCGCCCCGGCGAAGAAGGACGAAGCCCGCGCGCTGGTGACCGGCTGGCTGAGCA
CCCTGCCCGCCACGGACGTGGAGATCTGGGTGCGGGTGAACCCCGGTGACCTCGGCCTCCAGGACGCTCGAGCGGTCCTC
GCGCCCCGGGTGCGCGGTCTCGTCGCGGCGAAGACCGAGTCCGCCGAGGGGCTGCGGGTGCTCGCCGCCGAGGCGGCAGC
CGCGGAGGACCGCCTCGAGCTGCCTCGGGGCGCCTTCGGGCTGGTGCCGCTCCTGGAGTCCGCGCGCGCCCTGCTCGCCG
CGACCGAGATCGCGGCCGTTCCCGGCGTGGTGCGGCTGCAGGTCGGGGAGGCCGACCTCGCGGCCGACCTCGGGTTCGCG
CGGCAGGACGACCAGGCACCGTGGGACACCATCCGCACGCAGACGGTGATCGTGAGCGCGGCCGCCGGGATCGAGGCGCC
GGTCGCTCCCGTCTCCACCGACTTCCGCGACCTGGACGGGTTCGCTGCATCGACGCGGGCGCTCGCCGCCCGGGGCTTCG
TGGGTCGGGCGTGCATCCATCCGGCCCAGGTCGCGGTCGCGAACGAGGTCTTCACCCCGCGGCCCGAGGACGTCGGTCAT
GCCCGGGCGCTGATCGCCGCCTTCGACGAGGCGGTGGCCCGGGGGGTGGGCGTGATCCTCGGGGAGGACGGCCGGATGAT
CGACGAGGCCGTGGTCCGCAACGCGCGGCGGACGGTCGCGCTCGCCCGCTGA

Upstream 100 bases:

>100_bases
TCGGCCGAGACCGGACGTCGTCGCTCGGCCGAAGACCCCGTTGACGGCGGCGGGGCCTGCCGTTACATTAGCCGAAACGC
TGTTCCAATTTGGAGATGAT

Downstream 100 bases:

>100_bases
CGATCAGGCGTGACGACGAAGGACGAGAGGGACCGAATGAGCCTGCGTTACATCCGAGAGGTCGTGGTCGCGAGCGCCGA
CGTGCGCACCGCCGCGACCT

Product: HpcH/HpaI aldolase

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MIPRSYLYVPGDDAAKLEKATSRGADALIVDLEDAVAPAKKDEARALVTGWLSTLPATDVEIWVRVNPGDLGLQDARAVL
APRVRGLVAAKTESAEGLRVLAAEAAAAEDRLELPRGAFGLVPLLESARALLAATEIAAVPGVVRLQVGEADLAADLGFA
RQDDQAPWDTIRTQTVIVSAAAGIEAPVAPVSTDFRDLDGFAASTRALAARGFVGRACIHPAQVAVANEVFTPRPEDVGH
ARALIAAFDEAVARGVGVILGEDGRMIDEAVVRNARRTVALAR

Sequences:

>Translated_283_residues
MIPRSYLYVPGDDAAKLEKATSRGADALIVDLEDAVAPAKKDEARALVTGWLSTLPATDVEIWVRVNPGDLGLQDARAVL
APRVRGLVAAKTESAEGLRVLAAEAAAAEDRLELPRGAFGLVPLLESARALLAATEIAAVPGVVRLQVGEADLAADLGFA
RQDDQAPWDTIRTQTVIVSAAAGIEAPVAPVSTDFRDLDGFAASTRALAARGFVGRACIHPAQVAVANEVFTPRPEDVGH
ARALIAAFDEAVARGVGVILGEDGRMIDEAVVRNARRTVALAR
>Mature_283_residues
MIPRSYLYVPGDDAAKLEKATSRGADALIVDLEDAVAPAKKDEARALVTGWLSTLPATDVEIWVRVNPGDLGLQDARAVL
APRVRGLVAAKTESAEGLRVLAAEAAAAEDRLELPRGAFGLVPLLESARALLAATEIAAVPGVVRLQVGEADLAADLGFA
RQDDQAPWDTIRTQTVIVSAAAGIEAPVAPVSTDFRDLDGFAASTRALAARGFVGRACIHPAQVAVANEVFTPRPEDVGH
ARALIAAFDEAVARGVGVILGEDGRMIDEAVVRNARRTVALAR

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=297, Percent_Identity=34.6801346801347, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI87081764, Length=276, Percent_Identity=30.7971014492754, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17557458, Length=295, Percent_Identity=28.135593220339, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 29588; Mature: 29588

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPRSYLYVPGDDAAKLEKATSRGADALIVDLEDAVAPAKKDEARALVTGWLSTLPATDV
CCCCCEEEECCCCHHHHHHHHCCCCCEEEEECHHHHCCCCCHHHHHHHHHHHHHCCCCCE
EIWVRVNPGDLGLQDARAVLAPRVRGLVAAKTESAEGLRVLAAEAAAAEDRLELPRGAFG
EEEEEECCCCCCHHHHHHHHHHHHHHEEEECCCCCCCEEEEEHHHHHHHHHHCCCCCCHH
LVPLLESARALLAATEIAAVPGVVRLQVGEADLAADLGFARQDDQAPWDTIRTQTVIVSA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCCCCCCHHHHHHEEEEEEE
AAGIEAPVAPVSTDFRDLDGFAASTRALAARGFVGRACIHPAQVAVANEVFTPRPEDVGH
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCHHHCCHHHHHHHHCCCCCCCCCHHH
ARALIAAFDEAVARGVGVILGEDGRMIDEAVVRNARRTVALAR
HHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHEEECC
>Mature Secondary Structure
MIPRSYLYVPGDDAAKLEKATSRGADALIVDLEDAVAPAKKDEARALVTGWLSTLPATDV
CCCCCEEEECCCCHHHHHHHHCCCCCEEEEECHHHHCCCCCHHHHHHHHHHHHHCCCCCE
EIWVRVNPGDLGLQDARAVLAPRVRGLVAAKTESAEGLRVLAAEAAAAEDRLELPRGAFG
EEEEEECCCCCCHHHHHHHHHHHHHHEEEECCCCCCCEEEEEHHHHHHHHHHCCCCCCHH
LVPLLESARALLAATEIAAVPGVVRLQVGEADLAADLGFARQDDQAPWDTIRTQTVIVSA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCCCCCCHHHHHHEEEEEEE
AAGIEAPVAPVSTDFRDLDGFAASTRALAARGFVGRACIHPAQVAVANEVFTPRPEDVGH
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCHHHCCHHHHHHHHCCCCCCCCCHHH
ARALIAAFDEAVARGVGVILGEDGRMIDEAVVRNARRTVALAR
HHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2205500; 7830578 [H]