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The map label for this gene is map [H]

Identifier: 119718103

GI number: 119718103

Start: 4098702

End: 4099520

Strand: Reverse

Name: map [H]

Synonym: Noca_3883

Alternate gene names: 119718103

Gene position: 4099520-4098702 (Counterclockwise)

Preceding gene: 119718104

Following gene: 119718102

Centisome position: 82.22

GC content: 71.79

Gene sequence:

>819_bases
ATGGGCTTCCTCGACCGCGGGATCGAGATCAAGACACCCGAGCAGATCGCCGGGATGCGCAAGGCCGGCCTGGTGGTGGG
CCGGACCTTGGAGCTGCTGCGCGGCCACGTGCGGGCCGGCATCACGACCGGGGAGCTGGACACGATCGCGGAGGACCACA
TCCGGTCCTCGGGCGCGACCCCGTCGTTCCAGGGCTACCACGGCTTCCCCGCCTCGATCTGCGCGTCGGTCAACGACGAG
GTCGTCCACGGCATCCCGGGTGAGCGCGTGATCGCCGAGGGCGACGTCGTCTCGATCGACTGTGGCGCCATCGTCGACGG
GTGGCACGGTGACGCCGCCATCACCGTCGCTGTGGGCGCGGTCAGCCGGGAGCTCACCGAGCTGATGCGGGTGACCGAGG
AGGCGATGTGGCACGGCATCGCTGCGGCCCGGCTCGGCGGGCGGGTCACCGACATCTCGCACGCCGTCGAGCGGCAGGTG
CGTGGCCAGGGCAGCTACGGGATCCTCGAGGACTACACCGGCCATGGCATCGGCTCCCAGATGCACCAGCCCCCGAACGT
CCCGAACTACGGTCGGCCGGGCAAGGGCCCGAGGCTGGTCGAGGGCCTGGCCCTCGCCGTCGAGCCGATGATCACCCTCG
GCGCCAAGGACACCTCGGTGCTCGAGGACGACTGGACGGTGGTCACCGACGACGGGAGCTGGGCCGCGCACTTCGAGCAC
ACCTTCACGCTCACGCCGCGCGGGACCTGGGTGCTGACCGCCCTGGACGGCGGCGAGGCGGCCCTGACCGCGCTCGGCGT
GCGCTACGGCGGGGACTGA

Upstream 100 bases:

>100_bases
GACCTCGTGCACGAGGTCGACGGCATCGGCGAGGTCGACGAGGTCACCGCCCGGATCTTCCAGGCGCTGGACGTCATCCC
TGAGTCGTGACTCTCGACTG

Downstream 100 bases:

>100_bases
CCGGGTCGACCCGGGCCCCGAATCGCGTTCCGCGGTGGCGGCGTGGAATGATGGCTCCCGCCAGGAGGGGAGTATTCCCC
GCGGTGGTGTCGTCAGTACG

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MGFLDRGIEIKTPEQIAGMRKAGLVVGRTLELLRGHVRAGITTGELDTIAEDHIRSSGATPSFQGYHGFPASICASVNDE
VVHGIPGERVIAEGDVVSIDCGAIVDGWHGDAAITVAVGAVSRELTELMRVTEEAMWHGIAAARLGGRVTDISHAVERQV
RGQGSYGILEDYTGHGIGSQMHQPPNVPNYGRPGKGPRLVEGLALAVEPMITLGAKDTSVLEDDWTVVTDDGSWAAHFEH
TFTLTPRGTWVLTALDGGEAALTALGVRYGGD

Sequences:

>Translated_272_residues
MGFLDRGIEIKTPEQIAGMRKAGLVVGRTLELLRGHVRAGITTGELDTIAEDHIRSSGATPSFQGYHGFPASICASVNDE
VVHGIPGERVIAEGDVVSIDCGAIVDGWHGDAAITVAVGAVSRELTELMRVTEEAMWHGIAAARLGGRVTDISHAVERQV
RGQGSYGILEDYTGHGIGSQMHQPPNVPNYGRPGKGPRLVEGLALAVEPMITLGAKDTSVLEDDWTVVTDDGSWAAHFEH
TFTLTPRGTWVLTALDGGEAALTALGVRYGGD
>Mature_271_residues
GFLDRGIEIKTPEQIAGMRKAGLVVGRTLELLRGHVRAGITTGELDTIAEDHIRSSGATPSFQGYHGFPASICASVNDEV
VHGIPGERVIAEGDVVSIDCGAIVDGWHGDAAITVAVGAVSRELTELMRVTEEAMWHGIAAARLGGRVTDISHAVERQVR
GQGSYGILEDYTGHGIGSQMHQPPNVPNYGRPGKGPRLVEGLALAVEPMITLGAKDTSVLEDDWTVVTDDGSWAAHFEHT
FTLTPRGTWVLTALDGGEAALTALGVRYGGD

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=36.5461847389558, Blast_Score=165, Evalue=4e-41,
Organism=Homo sapiens, GI164420681, Length=246, Percent_Identity=33.3333333333333, Blast_Score=154, Evalue=8e-38,
Organism=Escherichia coli, GI1786364, Length=249, Percent_Identity=36.9477911646586, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1788728, Length=252, Percent_Identity=26.1904761904762, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=258, Percent_Identity=34.1085271317829, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6323273, Length=252, Percent_Identity=33.7301587301587, Blast_Score=165, Evalue=6e-42,
Organism=Drosophila melanogaster, GI21355531, Length=250, Percent_Identity=36.8, Blast_Score=164, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24583427, Length=247, Percent_Identity=35.6275303643725, Blast_Score=159, Evalue=1e-39,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 28738; Mature: 28606

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFLDRGIEIKTPEQIAGMRKAGLVVGRTLELLRGHVRAGITTGELDTIAEDHIRSSGAT
CCCCCCCCEECCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
PSFQGYHGFPASICASVNDEVVHGIPGERVIAEGDVVSIDCGAIVDGWHGDAAITVAVGA
CCCCCCCCCHHHHHHCCCCHHCCCCCCCEEEECCCEEEEECCCEEECCCCCEEEEEEHHH
VSRELTELMRVTEEAMWHGIAAARLGGRVTDISHAVERQVRGQGSYGILEDYTGHGIGSQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
MHQPPNVPNYGRPGKGPRLVEGLALAVEPMITLGAKDTSVLEDDWTVVTDDGSWAAHFEH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCEECCCCEEEECCCCEEEEEEE
TFTLTPRGTWVLTALDGGEAALTALGVRYGGD
EEEECCCCCEEEEEECCCCEEEHHEEEEECCC
>Mature Secondary Structure 
GFLDRGIEIKTPEQIAGMRKAGLVVGRTLELLRGHVRAGITTGELDTIAEDHIRSSGAT
CCCCCCCEECCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
PSFQGYHGFPASICASVNDEVVHGIPGERVIAEGDVVSIDCGAIVDGWHGDAAITVAVGA
CCCCCCCCCHHHHHHCCCCHHCCCCCCCEEEECCCEEEEECCCEEECCCCCEEEEEEHHH
VSRELTELMRVTEEAMWHGIAAARLGGRVTDISHAVERQVRGQGSYGILEDYTGHGIGSQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
MHQPPNVPNYGRPGKGPRLVEGLALAVEPMITLGAKDTSVLEDDWTVVTDDGSWAAHFEH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCEECCCCEEEECCCCEEEEEEE
TFTLTPRGTWVLTALDGGEAALTALGVRYGGD
EEEECCCCCEEEEEECCCCEEEHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]