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The map label for this gene is add5 [H]

Identifier: 119717755

GI number: 119717755

Start: 3743754

End: 3744875

Strand: Reverse

Name: add5 [H]

Synonym: Noca_3533

Alternate gene names: 119717755

Gene position: 3744875-3743754 (Counterclockwise)

Preceding gene: 119717757

Following gene: 119717749

Centisome position: 75.11

GC content: 71.03

Gene sequence:

>1122_bases
ATGACCGTGTCGCCGAGCCCGTCCCCGAACCCGTCCCCGACCCTCGACCAGGTGCAGCGGGCGCCGAAGGCGCTGCTGCA
CGACCACCTGGACGGCGGGCTGCGGCCCCAGTCGATCATCGAGCTCGCAGCGGAGATCGGGCACCAGCTGCCGGCCGTGG
AGGGCGACCTGTCCGCCGAGTCGCTCGGCCGCTGGTTCGCGGAGGCCGCCGACTCCGGCTCGCTGGAGCGCTACCTGGAG
ACCTTCGACCACACGGTCTCGGTGATGCAGACGGCCTCGGCGCTGACCCGGGTGGCGCGGGAGTGCGTGGAGGACCTGGT
CGCCGACGGCGTGGTGTACGCCGAGGTCCGCTACGCGCCCGAGCAGCACGTGGTCCAGGGGCTGAGCCTCGACGAGGTCG
TCGCGGCGGTCCAGGAGGGCTTCGACCAGGGCGTGGAGGCGGCCGGCGGGCGGATCGTCGTCCGCCAGCTGCTCACCGCG
ATGCGGCACCAGGCTCGGTCGATGGAGATCGCCCACCTCGCGGTCGCGTGGCGCGATCGCGGCGTCGCCGGCTTCGACAT
CGCCGGTGCCGAGGCCGGCTATCCCCCCACCCGCCACCTGGACGCGTTCGAGTACCTGCAGCGGGAGAACGCCCACTTCA
CGATCCACGCCGGCGAGGGCTTCGGGCTGCCGTCGATCTGGCAGGCCATCCAGTGGTGTGGCGCCGACCGGCTCGGGCAC
GGCGTCCGGATCATCGACGACATCACGGTCGCCGAGGACGGGGCCGTGAGCCTCGGCCTGCTGGCGGCGTACGTCCGCGA
CAAGCGGATCCCGCTGGAGATGTGCCCCTGGTCGAACGTGCAGACCGGCGCGGCCACCTCGATCGCCGAGCACCCGATCG
GGCTGCTGAAGCGGCTCGGCTTCCGGGTGACGGTGAACACCGACAACCGGCTGATGAGCCGCACCTCCGTGACCCACGAG
CTGTGGTCGTTGGTCGAGGCGTTCGGCTACGGGTTGAAGGACCTGGAGTGGTTCACGATCAACGCGATGAAGTCGGCGTT
CCTGCCCTTCGACGAGCGGCTGGCGCTGATCACCGATGTGATCAAGCCGGAGTACGCCGTGCTCAAGGCCGAGCACGCGT
GA

Upstream 100 bases:

>100_bases
GCGGCGACCTGTTCCAGGGTCGTGAAGACGCGCATGCCGGGAACCTACCGGTCCGCCGCAGTCGGCGCGGACCGGGGCCC
AGAGGTGAAAGGATCGCGGC

Downstream 100 bases:

>100_bases
TTCAGTCGGGCAGGACCGCCCACCAGGCGTGGTCCCAGCCGGCCAGGCCCAGCCGGGCCGACGCGAACTCGGTGCGCGAG
ACGTCCACCAGGCGCCCGCG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase 5 [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTVSPSPSPNPSPTLDQVQRAPKALLHDHLDGGLRPQSIIELAAEIGHQLPAVEGDLSAESLGRWFAEAADSGSLERYLE
TFDHTVSVMQTASALTRVARECVEDLVADGVVYAEVRYAPEQHVVQGLSLDEVVAAVQEGFDQGVEAAGGRIVVRQLLTA
MRHQARSMEIAHLAVAWRDRGVAGFDIAGAEAGYPPTRHLDAFEYLQRENAHFTIHAGEGFGLPSIWQAIQWCGADRLGH
GVRIIDDITVAEDGAVSLGLLAAYVRDKRIPLEMCPWSNVQTGAATSIAEHPIGLLKRLGFRVTVNTDNRLMSRTSVTHE
LWSLVEAFGYGLKDLEWFTINAMKSAFLPFDERLALITDVIKPEYAVLKAEHA

Sequences:

>Translated_373_residues
MTVSPSPSPNPSPTLDQVQRAPKALLHDHLDGGLRPQSIIELAAEIGHQLPAVEGDLSAESLGRWFAEAADSGSLERYLE
TFDHTVSVMQTASALTRVARECVEDLVADGVVYAEVRYAPEQHVVQGLSLDEVVAAVQEGFDQGVEAAGGRIVVRQLLTA
MRHQARSMEIAHLAVAWRDRGVAGFDIAGAEAGYPPTRHLDAFEYLQRENAHFTIHAGEGFGLPSIWQAIQWCGADRLGH
GVRIIDDITVAEDGAVSLGLLAAYVRDKRIPLEMCPWSNVQTGAATSIAEHPIGLLKRLGFRVTVNTDNRLMSRTSVTHE
LWSLVEAFGYGLKDLEWFTINAMKSAFLPFDERLALITDVIKPEYAVLKAEHA
>Mature_372_residues
TVSPSPSPNPSPTLDQVQRAPKALLHDHLDGGLRPQSIIELAAEIGHQLPAVEGDLSAESLGRWFAEAADSGSLERYLET
FDHTVSVMQTASALTRVARECVEDLVADGVVYAEVRYAPEQHVVQGLSLDEVVAAVQEGFDQGVEAAGGRIVVRQLLTAM
RHQARSMEIAHLAVAWRDRGVAGFDIAGAEAGYPPTRHLDAFEYLQRENAHFTIHAGEGFGLPSIWQAIQWCGADRLGHG
VRIIDDITVAEDGAVSLGLLAAYVRDKRIPLEMCPWSNVQTGAATSIAEHPIGLLKRLGFRVTVNTDNRLMSRTSVTHEL
WSLVEAFGYGLKDLEWFTINAMKSAFLPFDERLALITDVIKPEYAVLKAEHA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=371, Percent_Identity=29.1105121293801, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI1787910, Length=336, Percent_Identity=31.25, Blast_Score=155, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17538512, Length=366, Percent_Identity=30.6010928961749, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI32565969, Length=352, Percent_Identity=31.5340909090909, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6324188, Length=298, Percent_Identity=23.8255033557047, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 40745; Mature: 40613

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSPSPSPNPSPTLDQVQRAPKALLHDHLDGGLRPQSIIELAAEIGHQLPAVEGDLSAE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHH
SLGRWFAEAADSGSLERYLETFDHTVSVMQTASALTRVARECVEDLVADGVVYAEVRYAP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECC
EQHVVQGLSLDEVVAAVQEGFDQGVEAAGGRIVVRQLLTAMRHQARSMEIAHLAVAWRDR
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVAGFDIAGAEAGYPPTRHLDAFEYLQRENAHFTIHAGEGFGLPSIWQAIQWCGADRLGH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCHHHCC
GVRIIDDITVAEDGAVSLGLLAAYVRDKRIPLEMCPWSNVQTGAATSIAEHPIGLLKRLG
CCEEEECEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCC
FRVTVNTDNRLMSRTSVTHELWSLVEAFGYGLKDLEWFTINAMKSAFLPFDERLALITDV
CEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHCCCHHHHHHHHHHH
IKPEYAVLKAEHA
HCCCHHHEECCCC
>Mature Secondary Structure 
TVSPSPSPNPSPTLDQVQRAPKALLHDHLDGGLRPQSIIELAAEIGHQLPAVEGDLSAE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHH
SLGRWFAEAADSGSLERYLETFDHTVSVMQTASALTRVARECVEDLVADGVVYAEVRYAP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECC
EQHVVQGLSLDEVVAAVQEGFDQGVEAAGGRIVVRQLLTAMRHQARSMEIAHLAVAWRDR
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVAGFDIAGAEAGYPPTRHLDAFEYLQRENAHFTIHAGEGFGLPSIWQAIQWCGADRLGH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCHHHCC
GVRIIDDITVAEDGAVSLGLLAAYVRDKRIPLEMCPWSNVQTGAATSIAEHPIGLLKRLG
CCEEEECEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCC
FRVTVNTDNRLMSRTSVTHELWSLVEAFGYGLKDLEWFTINAMKSAFLPFDERLALITDV
CEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHCCCHHHHHHHHHHH
IKPEYAVLKAEHA
HCCCHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]