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The map label for this gene is afsQ1 [H]

Identifier: 119717722

GI number: 119717722

Start: 3708480

End: 3709550

Strand: Reverse

Name: afsQ1 [H]

Synonym: Noca_3500

Alternate gene names: 119717722

Gene position: 3709550-3708480 (Counterclockwise)

Preceding gene: 119717723

Following gene: 119717716

Centisome position: 74.4

GC content: 71.06

Gene sequence:

>1071_bases
ATGCAGGCGGGCAGCGACTGGGTGGCAGTCATCATCGAGGATGACCCAGATGTGCGCGACCTGATCGACATCGTGCTGAC
CCAGTCCGGGTTCCGCACGGTCGTCACGGAGAACGGCCCGGACGGGGTGGAGGCGGTGCGCCAGCACAACCCGCTGCTCA
CCACGCTCGACGTGAACATGCCCGGGATGGACGGCTTCGCCGCGGCCAAGCGGCTGCGGGAGTTCAGCAACACCTACCTG
ATCATGATCACCGCGCTCGCCGACGAGATCGACGTCGTACAGGGCTTCGAGGCCGGTGCCGACGACTACCTGGTCAAGCC
GTTCCGGCCGCGTGAACTGCGGGCCCGCGCGGACTCGATGCTGCGTCGTCCGCGGACCCGCTACGACACGCCCGCGGGCT
GGGCGGACGATGACGGCCAGGCCGTGGAGCACCACCCCCATCAAGAGTCCTGGGCGGCCGCCGCGGCCCGCGACCTCGCT
GCCAACCATCCACTGCAGCCGATCCACCTCGAGCCGATTCCTCCGGCCCAGCAGCCGGCTCCGCCGCTTGCGCCTCAGCC
TCAGCAGCCGGCGCCGCAGCCCTACCAGCCGGCGCCGCCCGTCGAGCCGGTCTACCAGCAGCCGCAGCACTACCCGCCCG
CGACGTACCAGCAGCCGCCGCAGCAGCAGCCGGTGCCGCTGCAGCAGGCTCCGGCGTACCCGCAGCACGCTGCGGACGCG
GCCGGGGCACCGCACGCCGACGGTGGCTGGGTCCGCCTGAACGGGCTCGCCCTCAACAACGAGACCCGGGTCGTCACCGT
CAACGGCGCAGCGGTGGACCTGACCCGCACCGAGTTCGACCTGCTCGCCTCGCTGCTGAGTACCGGCCGGCGGGTGCGCA
GCAAGGCCGACCTGGTGCTCACCATGCGCGGCCAGCAGTACGTCACGTCGTACTTCGTGAACGAGGCCGACAAGCGCTCG
GTCGAGGTACACATCGCGAACCTGCGCCGCAAGATCGGCGACGACGCGGCCACGCCGCGCTACATCGAGACGGTCCGCGG
CGTCGGCTACCGGCTCGCCGAGTCCGTCTGA

Upstream 100 bases:

>100_bases
CTCGTCCGGGTGGTGAGAATCACCCGACCCGGGCAGAACACCGGCGCGCGGGCGCCGGGCCTTTCGGTGCGGACAGGCGC
GCGTTGTTAGCATTCGCCAC

Downstream 100 bases:

>100_bases
GCCCTGGCCGTGGTCCGCGCGTGCCGGCGGCCCCGCCGACGCGGGTCGGCGGGTGGGGTCAGTGGATATGTCGTGACGAG
GTGACCTGGTAGGTCCGGGC

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MQAGSDWVAVIIEDDPDVRDLIDIVLTQSGFRTVVTENGPDGVEAVRQHNPLLTTLDVNMPGMDGFAAAKRLREFSNTYL
IMITALADEIDVVQGFEAGADDYLVKPFRPRELRARADSMLRRPRTRYDTPAGWADDDGQAVEHHPHQESWAAAAARDLA
ANHPLQPIHLEPIPPAQQPAPPLAPQPQQPAPQPYQPAPPVEPVYQQPQHYPPATYQQPPQQQPVPLQQAPAYPQHAADA
AGAPHADGGWVRLNGLALNNETRVVTVNGAAVDLTRTEFDLLASLLSTGRRVRSKADLVLTMRGQQYVTSYFVNEADKRS
VEVHIANLRRKIGDDAATPRYIETVRGVGYRLAESV

Sequences:

>Translated_356_residues
MQAGSDWVAVIIEDDPDVRDLIDIVLTQSGFRTVVTENGPDGVEAVRQHNPLLTTLDVNMPGMDGFAAAKRLREFSNTYL
IMITALADEIDVVQGFEAGADDYLVKPFRPRELRARADSMLRRPRTRYDTPAGWADDDGQAVEHHPHQESWAAAAARDLA
ANHPLQPIHLEPIPPAQQPAPPLAPQPQQPAPQPYQPAPPVEPVYQQPQHYPPATYQQPPQQQPVPLQQAPAYPQHAADA
AGAPHADGGWVRLNGLALNNETRVVTVNGAAVDLTRTEFDLLASLLSTGRRVRSKADLVLTMRGQQYVTSYFVNEADKRS
VEVHIANLRRKIGDDAATPRYIETVRGVGYRLAESV
>Mature_356_residues
MQAGSDWVAVIIEDDPDVRDLIDIVLTQSGFRTVVTENGPDGVEAVRQHNPLLTTLDVNMPGMDGFAAAKRLREFSNTYL
IMITALADEIDVVQGFEAGADDYLVKPFRPRELRARADSMLRRPRTRYDTPAGWADDDGQAVEHHPHQESWAAAAARDLA
ANHPLQPIHLEPIPPAQQPAPPLAPQPQQPAPQPYQPAPPVEPVYQQPQHYPPATYQQPPQQQPVPLQQAPAYPQHAADA
AGAPHADGGWVRLNGLALNNETRVVTVNGAAVDLTRTEFDLLASLLSTGRRVRSKADLVLTMRGQQYVTSYFVNEADKRS
VEVHIANLRRKIGDDAATPRYIETVRGVGYRLAESV

Specific function: Forms part of a two-component regulatory system AfsQ1/AfsQ2 involved in secondary metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=116, Percent_Identity=37.9310344827586, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789809, Length=119, Percent_Identity=38.655462184874, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1790863, Length=114, Percent_Identity=34.2105263157895, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790860, Length=133, Percent_Identity=34.5864661654135, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=38.4615384615385, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787229, Length=114, Percent_Identity=36.8421052631579, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI2367329, Length=114, Percent_Identity=39.4736842105263, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082012, Length=114, Percent_Identity=35.0877192982456, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786911, Length=115, Percent_Identity=34.7826086956522, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786784, Length=115, Percent_Identity=34.7826086956522, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790299, Length=109, Percent_Identity=34.8623853211009, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788550, Length=105, Percent_Identity=32.3809523809524, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 39168; Mature: 39168

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAGSDWVAVIIEDDPDVRDLIDIVLTQSGFRTVVTENGPDGVEAVRQHNPLLTTLDVNM
CCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCC
PGMDGFAAAKRLREFSNTYLIMITALADEIDVVQGFEAGADDYLVKPFRPRELRARADSM
CCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHH
LRRPRTRYDTPAGWADDDGQAVEHHPHQESWAAAAARDLAANHPLQPIHLEPIPPAQQPA
HHCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCC
PPLAPQPQQPAPQPYQPAPPVEPVYQQPQHYPPATYQQPPQQQPVPLQQAPAYPQHAADA
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHC
AGAPHADGGWVRLNGLALNNETRVVTVNGAAVDLTRTEFDLLASLLSTGRRVRSKADLVL
CCCCCCCCCEEEEEEEEECCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEE
TMRGQQYVTSYFVNEADKRSVEVHIANLRRKIGDDAATPRYIETVRGVGYRLAESV
EECCHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MQAGSDWVAVIIEDDPDVRDLIDIVLTQSGFRTVVTENGPDGVEAVRQHNPLLTTLDVNM
CCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCC
PGMDGFAAAKRLREFSNTYLIMITALADEIDVVQGFEAGADDYLVKPFRPRELRARADSM
CCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHH
LRRPRTRYDTPAGWADDDGQAVEHHPHQESWAAAAARDLAANHPLQPIHLEPIPPAQQPA
HHCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCC
PPLAPQPQQPAPQPYQPAPPVEPVYQQPQHYPPATYQQPPQQQPVPLQQAPAYPQHAADA
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHC
AGAPHADGGWVRLNGLALNNETRVVTVNGAAVDLTRTEFDLLASLLSTGRRVRSKADLVL
CCCCCCCCCEEEEEEEEECCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEE
TMRGQQYVTSYFVNEADKRSVEVHIANLRRKIGDDAATPRYIETVRGVGYRLAESV
EECCHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339426; 12000953 [H]