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The map label for this gene is clpP1 [H]

Identifier: 119717699

GI number: 119717699

Start: 3687144

End: 3687731

Strand: Reverse

Name: clpP1 [H]

Synonym: Noca_3477

Alternate gene names: 119717699

Gene position: 3687731-3687144 (Counterclockwise)

Preceding gene: 119717700

Following gene: 119717698

Centisome position: 73.96

GC content: 67.52

Gene sequence:

>588_bases
ATGAACGTGCTCGACGACCACATCTACCAGCGGCTGCTGCGCGAGCGGATCGTCTTCCTCGGCTCCGAGGTGCGTGACCA
GAACGCGAACGCGATCTGCGCCCAGCTGCTGCTGCTCTCGGCGGAGGACCCCGAGGCGGACATCTTCCTCCACATCAACT
CGCCCGGTGGCTCGGTCGACGCGGGCATGGCGATCTACGACACCATGAACTACATCCCCAACGACGTCGCCACCGTCGGG
ATGGGGCTGGCCGCCTCGATGGGCCAGTTCCTGCTCTGCGCGGGCACCAAGGGCAAGCGCTACGCGCTGCCGCACGCGCG
GATCATGATGCACCAGCCCTCCTCCGGCATGGGCGGCTCGGCCTCGGACATCAAGATCCAGGCCCAGCAGTCGCTGCACA
TCAAGAAGGTCCTGCTCGAGCTGATCGCCGAGCACACCGGCCAGACGGTCGAGCAGATCGAGATGGACGCCGACCGCGAC
CGGTGGTTCACCGCCGACCAGGCCAAGGAGTACGGCCTGGTCGACCAGGTCATCAAGAGCGCTCGCGAGGCCGCCGACGA
CGGCCGCCCGGCCCGGCAGAAGGACTGA

Upstream 100 bases:

>100_bases
GGCGAACAGCGGGGGATTGGCAGTGGTTCTGTCCTCCCTTCCGGCTAGGGTCGCTCTCGTGACCCAGAACTCCAGCCCAC
AGCTCAACGGCGGCGCGGGC

Downstream 100 bases:

>100_bases
CCCGAATGTCTGAGATGAACTACTACATCCCGCAGTGGGAAGAGCGCACGTCGTACGGCTTCCGGCGCATCGACCCCTAC
GCCAAGCTGTTCGAGGACCG

Product: ClpP1 peptidase

Products: NA

Alternate protein names: Endopeptidase Clp 1 [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MNVLDDHIYQRLLRERIVFLGSEVRDQNANAICAQLLLLSAEDPEADIFLHINSPGGSVDAGMAIYDTMNYIPNDVATVG
MGLAASMGQFLLCAGTKGKRYALPHARIMMHQPSSGMGGSASDIKIQAQQSLHIKKVLLELIAEHTGQTVEQIEMDADRD
RWFTADQAKEYGLVDQVIKSAREAADDGRPARQKD

Sequences:

>Translated_195_residues
MNVLDDHIYQRLLRERIVFLGSEVRDQNANAICAQLLLLSAEDPEADIFLHINSPGGSVDAGMAIYDTMNYIPNDVATVG
MGLAASMGQFLLCAGTKGKRYALPHARIMMHQPSSGMGGSASDIKIQAQQSLHIKKVLLELIAEHTGQTVEQIEMDADRD
RWFTADQAKEYGLVDQVIKSAREAADDGRPARQKD
>Mature_195_residues
MNVLDDHIYQRLLRERIVFLGSEVRDQNANAICAQLLLLSAEDPEADIFLHINSPGGSVDAGMAIYDTMNYIPNDVATVG
MGLAASMGQFLLCAGTKGKRYALPHARIMMHQPSSGMGGSASDIKIQAQQSLHIKKVLLELIAEHTGQTVEQIEMDADRD
RWFTADQAKEYGLVDQVIKSAREAADDGRPARQKD

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=180, Percent_Identity=47.7777777777778, Blast_Score=174, Evalue=4e-44,
Organism=Escherichia coli, GI1786641, Length=171, Percent_Identity=57.3099415204678, Blast_Score=213, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17538017, Length=170, Percent_Identity=51.7647058823529, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI20129427, Length=184, Percent_Identity=44.0217391304348, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 21411; Mature: 21411

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLDDHIYQRLLRERIVFLGSEVRDQNANAICAQLLLLSAEDPEADIFLHINSPGGSVD
CCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
AGMAIYDTMNYIPNDVATVGMGLAASMGQFLLCAGTKGKRYALPHARIMMHQPSSGMGGS
CCHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCEEECCCCEEEEECCCCCCCCC
ASDIKIQAQQSLHIKKVLLELIAEHTGQTVEQIEMDADRDRWFTADQAKEYGLVDQVIKS
CCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHH
AREAADDGRPARQKD
HHHHHCCCCCCCCCC
>Mature Secondary Structure
MNVLDDHIYQRLLRERIVFLGSEVRDQNANAICAQLLLLSAEDPEADIFLHINSPGGSVD
CCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
AGMAIYDTMNYIPNDVATVGMGLAASMGQFLLCAGTKGKRYALPHARIMMHQPSSGMGGS
CCHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCEEECCCCEEEEECCCCCCCCC
ASDIKIQAQQSLHIKKVLLELIAEHTGQTVEQIEMDADRDRWFTADQAKEYGLVDQVIKS
CCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHH
AREAADDGRPARQKD
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA