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The map label for this gene is mrdB [H]

Identifier: 119717683

GI number: 119717683

Start: 3669072

End: 3670313

Strand: Reverse

Name: mrdB [H]

Synonym: Noca_3461

Alternate gene names: 119717683

Gene position: 3670313-3669072 (Counterclockwise)

Preceding gene: 119717684

Following gene: 119717682

Centisome position: 73.61

GC content: 72.38

Gene sequence:

>1242_bases
GTGCCGACCCCCCGCTCCGGGCTCCGGACGTCCGGCCTCAGGCCCCCCGGTCTCAGGCCCCCCGGTCTCAGGGCCCCGGG
CCTCGACTGGGTGCTGATGCTCGCCGTTCTCGGGCTGGTCACGCTCGGGAGCCTCCTGGTGTGGTCGGCGACCACGCACC
GAGAGGACCTCACCGGGGGTGACCCCACGGCGTACCTGAAGAAGCAGGTCGTCAACGTGCTCATCGGTCTGGTGCTGATG
GTGGTCGTGCTCGCGACCGACCACCGCTGGGTCCGCATCGTCGCCCCGCTGGTGTACGTCGCCTCCCTCGGCGGCCTGGC
CCTCGTGCTGACGATGGGCACCACGATCAACGGCTCCCGGTCCTGGCTGCAGCTCGGGGGGATGTCCATCCAGCCCTCCG
AGTTCGCCAAGCTCGCCGTCGTGATCGGCATGGCGCTGTGGGTCGCGGAGCGCGCCGACGTGCGCAGGGGCCGGCCCGGC
GGCAGCCTCGGCGACGTCCTCGGCATGCTCGGCATCGCCGGGCTCCCGGCCGCGCTGATCATGCTCCAGCCCGACCTCGG
CACGATGCTCGTGCTCTCCGCGACCGTCTTCGGGGTCCTGGCGGTCTCCGGTGCACCGCGACGCTGGCTGGGCCTGCTGG
CCGCCGGTGGGGTCACCGCGGCGGCCGCCGCGGTCGCTGCCGGGTTCTTGAAGCAGTACCAGGTCGACCGCTTCCTCGCG
TTCACCAACCCCGACCTCGACCCGCGCGGGGCCGGCTACAACGTCGAGCAGGCGCGAATCGCGATCGGCAACGGCGGGCT
GTTCGGTCAGGGTCTCTTCGACGGCTCCCAGACCCGCGCCGGCTTCGTGCCCGAGCAGCACACCGACTTCGTGTTCACGG
TCGCGGGGGAGGAGCTCGGCCTGGTCGGCGCCGGCCTCCTGATCGCCCTGCTCGGGCTCGTCATCTGGCGGGCGCTGGCG
ATCTCGGCGCGCACCGACGACCCGTTCGGCCGGCTCGCGGCCGCCGGCATCGCCTGCTGGTTCGGCTTCCAGGCGTTCCA
GAACGTCGGGATGTGCCTGGGCATCATGCCGGTCACCGGCGTCCCGCTGCCGTTCGTGTCGTACGGGGGCAGCTCGATGT
TCGCCGGCATGCTCGCGATCGGGCTGCTCCAGAACATCCACCTGCGCTCCACCCAGAGCCTCCCGTTGCGCCACGCGCTG
CCGCTGCGTGCGGTCCGCTCCGGGCTCAGCGTCAGGGCTTGA

Upstream 100 bases:

>100_bases
GGCACCACGCCGCCCGAGCGGCTGCCGACGTTCATGAAGGACGGCACCATCCTGCCGCCGGCCGAGCAGGGCTCCGAGCG
CCGCGACGAGGAGGACTGAC

Downstream 100 bases:

>100_bases
GGACGGGGACCTGCGCTCGGCCAGGACATCGTGGGGAGGGGCCGGTGGGCCGGCTCGTGTTTGGATGGGGACATGAGCGA
CCGCGACATCGAGCCGGAGA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MPTPRSGLRTSGLRPPGLRPPGLRAPGLDWVLMLAVLGLVTLGSLLVWSATTHREDLTGGDPTAYLKKQVVNVLIGLVLM
VVVLATDHRWVRIVAPLVYVASLGGLALVLTMGTTINGSRSWLQLGGMSIQPSEFAKLAVVIGMALWVAERADVRRGRPG
GSLGDVLGMLGIAGLPAALIMLQPDLGTMLVLSATVFGVLAVSGAPRRWLGLLAAGGVTAAAAAVAAGFLKQYQVDRFLA
FTNPDLDPRGAGYNVEQARIAIGNGGLFGQGLFDGSQTRAGFVPEQHTDFVFTVAGEELGLVGAGLLIALLGLVIWRALA
ISARTDDPFGRLAAAGIACWFGFQAFQNVGMCLGIMPVTGVPLPFVSYGGSSMFAGMLAIGLLQNIHLRSTQSLPLRHAL
PLRAVRSGLSVRA

Sequences:

>Translated_413_residues
MPTPRSGLRTSGLRPPGLRPPGLRAPGLDWVLMLAVLGLVTLGSLLVWSATTHREDLTGGDPTAYLKKQVVNVLIGLVLM
VVVLATDHRWVRIVAPLVYVASLGGLALVLTMGTTINGSRSWLQLGGMSIQPSEFAKLAVVIGMALWVAERADVRRGRPG
GSLGDVLGMLGIAGLPAALIMLQPDLGTMLVLSATVFGVLAVSGAPRRWLGLLAAGGVTAAAAAVAAGFLKQYQVDRFLA
FTNPDLDPRGAGYNVEQARIAIGNGGLFGQGLFDGSQTRAGFVPEQHTDFVFTVAGEELGLVGAGLLIALLGLVIWRALA
ISARTDDPFGRLAAAGIACWFGFQAFQNVGMCLGIMPVTGVPLPFVSYGGSSMFAGMLAIGLLQNIHLRSTQSLPLRHAL
PLRAVRSGLSVRA
>Mature_412_residues
PTPRSGLRTSGLRPPGLRPPGLRAPGLDWVLMLAVLGLVTLGSLLVWSATTHREDLTGGDPTAYLKKQVVNVLIGLVLMV
VVLATDHRWVRIVAPLVYVASLGGLALVLTMGTTINGSRSWLQLGGMSIQPSEFAKLAVVIGMALWVAERADVRRGRPGG
SLGDVLGMLGIAGLPAALIMLQPDLGTMLVLSATVFGVLAVSGAPRRWLGLLAAGGVTAAAAAVAAGFLKQYQVDRFLAF
TNPDLDPRGAGYNVEQARIAIGNGGLFGQGLFDGSQTRAGFVPEQHTDFVFTVAGEELGLVGAGLLIALLGLVIWRALAI
SARTDDPFGRLAAAGIACWFGFQAFQNVGMCLGIMPVTGVPLPFVSYGGSSMFAGMLAIGLLQNIHLRSTQSLPLRHALP
LRAVRSGLSVRA

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=367, Percent_Identity=33.7874659400545, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786853, Length=346, Percent_Identity=37.8612716763006, Blast_Score=182, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43109; Mature: 42977

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPRSGLRTSGLRPPGLRPPGLRAPGLDWVLMLAVLGLVTLGSLLVWSATTHREDLTGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DPTAYLKKQVVNVLIGLVLMVVVLATDHRWVRIVAPLVYVASLGGLALVLTMGTTINGSR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
SWLQLGGMSIQPSEFAKLAVVIGMALWVAERADVRRGRPGGSLGDVLGMLGIAGLPAALI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEE
MLQPDLGTMLVLSATVFGVLAVSGAPRRWLGLLAAGGVTAAAAAVAAGFLKQYQVDRFLA
EECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEE
FTNPDLDPRGAGYNVEQARIAIGNGGLFGQGLFDGSQTRAGFVPEQHTDFVFTVAGEELG
ECCCCCCCCCCCCCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
LVGAGLLIALLGLVIWRALAISARTDDPFGRLAAAGIACWFGFQAFQNVGMCLGIMPVTG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
VPLPFVSYGGSSMFAGMLAIGLLQNIHLRSTQSLPLRHALPLRAVRSGLSVRA
CCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PTPRSGLRTSGLRPPGLRPPGLRAPGLDWVLMLAVLGLVTLGSLLVWSATTHREDLTGG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DPTAYLKKQVVNVLIGLVLMVVVLATDHRWVRIVAPLVYVASLGGLALVLTMGTTINGSR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
SWLQLGGMSIQPSEFAKLAVVIGMALWVAERADVRRGRPGGSLGDVLGMLGIAGLPAALI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEE
MLQPDLGTMLVLSATVFGVLAVSGAPRRWLGLLAAGGVTAAAAAVAAGFLKQYQVDRFLA
EECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEE
FTNPDLDPRGAGYNVEQARIAIGNGGLFGQGLFDGSQTRAGFVPEQHTDFVFTVAGEELG
ECCCCCCCCCCCCCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
LVGAGLLIALLGLVIWRALAISARTDDPFGRLAAAGIACWFGFQAFQNVGMCLGIMPVTG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
VPLPFVSYGGSSMFAGMLAIGLLQNIHLRSTQSLPLRHALPLRAVRSGLSVRA
CCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]