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The map label for this gene is pfpI [H]

Identifier: 119717665

GI number: 119717665

Start: 3650649

End: 3651185

Strand: Reverse

Name: pfpI [H]

Synonym: Noca_3443

Alternate gene names: 119717665

Gene position: 3651185-3650649 (Counterclockwise)

Preceding gene: 119717666

Following gene: 119717662

Centisome position: 73.23

GC content: 72.25

Gene sequence:

>537_bases
ATGGGCGACCTGACAGGTAGGACCGTGGCCATCATCGCGACCGACCACTTCGAGGAGGCCGAGCTCGTCCAGCCACGCGA
CGCGCTGCGCGACGCGGGGGCGACGGTGCTCGTCTACTCGACCGGCACCGACCCGATCCAGGGAGTCGAGGGTGACACCA
CCCCGACGCAGAAGGTGGAGGTGGACGGCACCCTCGACGACCTCGACGTCGGGTCCGTCCAGGCCCTGGTCGTGCCCGGC
GGCACCGTCAACGCCGACCGGATCCGCACCGAGCCGCGCGCCCAGGACATCGCGCGCCAGGCGATGGAGGACGGCAAGCC
GCTGGCCGTCATCTGCCACGGGCCCTGGCTCCTCGTCTCGGCCGGACTGGCCCGCGGGCGGCGGCTGACCAGCTACCCCA
GCCTCGCCGACGACGTCCGCAACGCCGGCGGCACCTGGACCGACGAGGAGGTCGTCGTCGACGGCAACCTGATCACCAGC
CGCAGCCCCGAGGACCTGCCCGCCTTCATCAAGGCCCTGGAGGACGCGCTCTCCTGA

Upstream 100 bases:

>100_bases
GTGGGTACGCCGGGCGCTGGGGCTGCTGCGCACCAGCGCGGCCAGCCTGTCCGGCTGAGCCGGCCGCATCAGGCGGCTGC
TGTGCGGGTACCGACCGGCC

Downstream 100 bases:

>100_bases
CCCGTAACGCGCCGGTGCCCCACCCCCGGCGTGCGGGGATGGGGCACCGGCTTTCGCCACTCCTTGGGAGAGGGGACGTC
AGCCCACGTGCACGGGGGCC

Product: PfpI family intracellular peptidase

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MGDLTGRTVAIIATDHFEEAELVQPRDALRDAGATVLVYSTGTDPIQGVEGDTTPTQKVEVDGTLDDLDVGSVQALVVPG
GTVNADRIRTEPRAQDIARQAMEDGKPLAVICHGPWLLVSAGLARGRRLTSYPSLADDVRNAGGTWTDEEVVVDGNLITS
RSPEDLPAFIKALEDALS

Sequences:

>Translated_178_residues
MGDLTGRTVAIIATDHFEEAELVQPRDALRDAGATVLVYSTGTDPIQGVEGDTTPTQKVEVDGTLDDLDVGSVQALVVPG
GTVNADRIRTEPRAQDIARQAMEDGKPLAVICHGPWLLVSAGLARGRRLTSYPSLADDVRNAGGTWTDEEVVVDGNLITS
RSPEDLPAFIKALEDALS
>Mature_177_residues
GDLTGRTVAIIATDHFEEAELVQPRDALRDAGATVLVYSTGTDPIQGVEGDTTPTQKVEVDGTLDDLDVGSVQALVVPGG
TVNADRIRTEPRAQDIARQAMEDGKPLAVICHGPWLLVSAGLARGRRLTSYPSLADDVRNAGGTWTDEEVVVDGNLITSR
SPEDLPAFIKALEDALS

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=178, Percent_Identity=28.0898876404494, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI31543380, Length=178, Percent_Identity=28.0898876404494, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082219, Length=165, Percent_Identity=38.7878787878788, Blast_Score=121, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17531319, Length=155, Percent_Identity=27.0967741935484, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571932, Length=159, Percent_Identity=31.4465408805031, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 18847; Mature: 18716

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDLTGRTVAIIATDHFEEAELVQPRDALRDAGATVLVYSTGTDPIQGVEGDTTPTQKVE
CCCCCCCEEEEEEECCCCCCHHCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEE
VDGTLDDLDVGSVQALVVPGGTVNADRIRTEPRAQDIARQAMEDGKPLAVICHGPWLLVS
ECCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCHHEEH
AGLARGRRLTSYPSLADDVRNAGGTWTDEEVVVDGNLITSRSPEDLPAFIKALEDALS
HHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GDLTGRTVAIIATDHFEEAELVQPRDALRDAGATVLVYSTGTDPIQGVEGDTTPTQKVE
CCCCCCEEEEEEECCCCCCHHCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEE
VDGTLDDLDVGSVQALVVPGGTVNADRIRTEPRAQDIARQAMEDGKPLAVICHGPWLLVS
ECCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCHHEEH
AGLARGRRLTSYPSLADDVRNAGGTWTDEEVVVDGNLITSRSPEDLPAFIKALEDALS
HHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]