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The map label for this gene is ilvC [H]

Identifier: 119717613

GI number: 119717613

Start: 3593495

End: 3594523

Strand: Reverse

Name: ilvC [H]

Synonym: Noca_3390

Alternate gene names: 119717613

Gene position: 3594523-3593495 (Counterclockwise)

Preceding gene: 119717614

Following gene: 119717612

Centisome position: 72.09

GC content: 68.9

Gene sequence:

>1029_bases
GTGGCTGAGATGTTCTACGACGACGACGCCGACCTGTCCCTGATCCAGGGCAAGAACGTGGCCGTCATCGGCTACGGCAG
CCAGGGCCACGCCCACGCGCTGTCGCTGCGCGACTCGGGCGTCGACGTCCGCGTCGGCCTGCAGCCGGACTCCAAGAGCC
GGGCCAAGGCCGAGGCCGAGGGGCTGCGGGTGCTCACCCCGGCCGAGGCCGCGGAGGAGGCCGACGTCATCGTCATCCTC
GCCCCCGACCAGCACCAGCGGAAGCTGTACGCCGAGGAGATCGAGCCGAACATCACCGAGGGCGACACCCTGGTGTTCGG
GCACGGCTTCAACATCCGGTTCGGCTACATCACCCCGCCCGAGGGCGTGAACGTGTTCATGGTCGCGCCGAAGGGCCCGG
GCCACCTGGTGCGCCGCGAGTACGTCGACGGCCGGGGCGTCCCGGTCCTGGTCGCGGTCGAGAAGGACCCGTCCGGCGGC
ACCTGGGACCTCGCGCTGTCCTACGCGAAGGCGATCGGCGGGCTGCGCGCCGGCGGCATCAAGACCACCTTCACCGAGGA
GACCGAGACCGACCTGTTCGGCGAGCAGGCCGTGCTCTGCGGCGGCGCCTCGCAGCTGGTCATGTACGGCTTCGAGGTCC
TCACCGAGGCCGGCTACCAGCCCGAGGTCGCCTACTTCGAGTGCCTCCACGAGCTCAAGCTGATCGTCGACCTGATGTAC
GAGGGTGGCATCGCCAAGCAGCGCTGGTCGGTCTCCGACACCGCCGAGTACGGCGACTACGTCTCCGGCCCGCGGGTGAT
CACCCCGGAGGTGAAGAGGAACATGGAGGGCGTCCTCGCCGACATCAAGAACGGCTCCTTCGCCAAGCGCTTCATCGACG
ACATGGATGCCGGCTCGCCGGAGTTCAACGAGCTGCGCAAGAAGGGTGAGCAGCACCCGATCGAGCAGACCGGCCGCGAG
CTGCGCAAGCTGATGGCCTGGGTGAAGTCGCACGACTCCGACTACACCGAGGGCACCGCCACCCGCTGA

Upstream 100 bases:

>100_bases
CTCCGAGCGCAGCCTGCGCCCGGTCGCCATCCCCGCCCCGCCCGCTGCGGTTTGAAGCACCACACCCAACACGAAGGCCC
AACACGAAGGAGAAGCCCCC

Downstream 100 bases:

>100_bases
ACCACCCGTGACGAGGCCGGCGGAATGCGCCGGCCTCGTTGCGCGTTCAACCAGATATGCGCATCGAGATCTGGAGTGAC
GTCGTCTGTCCGTGGTGCTA

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MAEMFYDDDADLSLIQGKNVAVIGYGSQGHAHALSLRDSGVDVRVGLQPDSKSRAKAEAEGLRVLTPAEAAEEADVIVIL
APDQHQRKLYAEEIEPNITEGDTLVFGHGFNIRFGYITPPEGVNVFMVAPKGPGHLVRREYVDGRGVPVLVAVEKDPSGG
TWDLALSYAKAIGGLRAGGIKTTFTEETETDLFGEQAVLCGGASQLVMYGFEVLTEAGYQPEVAYFECLHELKLIVDLMY
EGGIAKQRWSVSDTAEYGDYVSGPRVITPEVKRNMEGVLADIKNGSFAKRFIDDMDAGSPEFNELRKKGEQHPIEQTGRE
LRKLMAWVKSHDSDYTEGTATR

Sequences:

>Translated_342_residues
MAEMFYDDDADLSLIQGKNVAVIGYGSQGHAHALSLRDSGVDVRVGLQPDSKSRAKAEAEGLRVLTPAEAAEEADVIVIL
APDQHQRKLYAEEIEPNITEGDTLVFGHGFNIRFGYITPPEGVNVFMVAPKGPGHLVRREYVDGRGVPVLVAVEKDPSGG
TWDLALSYAKAIGGLRAGGIKTTFTEETETDLFGEQAVLCGGASQLVMYGFEVLTEAGYQPEVAYFECLHELKLIVDLMY
EGGIAKQRWSVSDTAEYGDYVSGPRVITPEVKRNMEGVLADIKNGSFAKRFIDDMDAGSPEFNELRKKGEQHPIEQTGRE
LRKLMAWVKSHDSDYTEGTATR
>Mature_341_residues
AEMFYDDDADLSLIQGKNVAVIGYGSQGHAHALSLRDSGVDVRVGLQPDSKSRAKAEAEGLRVLTPAEAAEEADVIVILA
PDQHQRKLYAEEIEPNITEGDTLVFGHGFNIRFGYITPPEGVNVFMVAPKGPGHLVRREYVDGRGVPVLVAVEKDPSGGT
WDLALSYAKAIGGLRAGGIKTTFTEETETDLFGEQAVLCGGASQLVMYGFEVLTEAGYQPEVAYFECLHELKLIVDLMYE
GGIAKQRWSVSDTAEYGDYVSGPRVITPEVKRNMEGVLADIKNGSFAKRFIDDMDAGSPEFNELRKKGEQHPIEQTGREL
RKLMAWVKSHDSDYTEGTATR

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=304, Percent_Identity=34.2105263157895, Blast_Score=141, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6323387, Length=332, Percent_Identity=31.9277108433735, Blast_Score=116, Evalue=6e-27,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 37418; Mature: 37287

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEMFYDDDADLSLIQGKNVAVIGYGSQGHAHALSLRDSGVDVRVGLQPDSKSRAKAEAE
CCCCCCCCCCCEEEECCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHC
GLRVLTPAEAAEEADVIVILAPDQHQRKLYAEEIEPNITEGDTLVFGHGFNIRFGYITPP
CCEEECCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCC
EGVNVFMVAPKGPGHLVRREYVDGRGVPVLVAVEKDPSGGTWDLALSYAKAIGGLRAGGI
CCCEEEEECCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCE
KTTFTEETETDLFGEQAVLCGGASQLVMYGFEVLTEAGYQPEVAYFECLHELKLIVDLMY
EEEECCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
EGGIAKQRWSVSDTAEYGDYVSGPRVITPEVKRNMEGVLADIKNGSFAKRFIDDMDAGSP
CCCCCCCCCCCCCHHHHCCCCCCCEEECHHHHHCHHHHHHHCCCCHHHHHHHHHCCCCCC
EFNELRKKGEQHPIEQTGRELRKLMAWVKSHDSDYTEGTATR
CHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AEMFYDDDADLSLIQGKNVAVIGYGSQGHAHALSLRDSGVDVRVGLQPDSKSRAKAEAE
CCCCCCCCCCEEEECCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHC
GLRVLTPAEAAEEADVIVILAPDQHQRKLYAEEIEPNITEGDTLVFGHGFNIRFGYITPP
CCEEECCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCC
EGVNVFMVAPKGPGHLVRREYVDGRGVPVLVAVEKDPSGGTWDLALSYAKAIGGLRAGGI
CCCEEEEECCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCE
KTTFTEETETDLFGEQAVLCGGASQLVMYGFEVLTEAGYQPEVAYFECLHELKLIVDLMY
EEEECCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
EGGIAKQRWSVSDTAEYGDYVSGPRVITPEVKRNMEGVLADIKNGSFAKRFIDDMDAGSP
CCCCCCCCCCCCCHHHHCCCCCCCEEECHHHHHCHHHHHHHCCCCHHHHHHHHHCCCCCC
EFNELRKKGEQHPIEQTGRELRKLMAWVKSHDSDYTEGTATR
CHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA