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The map label for this gene is aac [H]

Identifier: 119717581

GI number: 119717581

Start: 3557383

End: 3557904

Strand: Reverse

Name: aac [H]

Synonym: Noca_3357

Alternate gene names: 119717581

Gene position: 3557904-3557383 (Counterclockwise)

Preceding gene: 119717582

Following gene: 119717580

Centisome position: 71.36

GC content: 73.56

Gene sequence:

>522_bases
GTGATCGTCCGCTGCGGCACCGACGAGCTGTCGGCGGTCGAGCTGGTCGAGACGCGGGCGCTGCTGGACGCCGCCTTCAC
CGACTTCAGCGATCACGACTGGTCCCACGCCCTCGGCGGTGTGCATGCCCTGGCTGTCGAGGAGGGCCGCGTGCTCGCCC
ACGGGTCGGTGGTGCCGAGGCGCCTGCTCCAGGGCGGGCACCCGCTGCACTGCGGGTACGTCGAGGCCGTCGCCGTCCGC
CCCGACGTGCAACGCCGGGGACTCGGGTCGGCGGTGATGACGGCGCTGGAGGACCTGGCGCCGGCGTACGACCTGCTCGC
GCTGAGTGCTTCGGCACGTGGTGTCCCGCTCTACCGCGCTCGCGGCTGGTCGCTGTGGCGCGGTCCCTCCTCCGTCCTGA
CCCTCGACGGGCCGGTGCCCACGCCGGACGACGACGGGTCGATCTACGTCCTACCCGGGGCGAGCGGCGTCGACCTGGAC
GGCCCGATCACGTGCGACTGGCGCGACGGCGACGTGTGGTGA

Upstream 100 bases:

>100_bases
GCCGCGCGCCCGGCCGAGGAGGAGCTGCTGCTCGCCCTGTCGGCCCAGGTGGAGGCGGCCGCACCGTGGTCGGACCGGCG
GCCGCCGGGATGGTGACGGC

Downstream 100 bases:

>100_bases
GCCTAGGGTGAGCCCATGAGCAGACCGGTGATCGTGGTGGTGGGTGCAGGCCCGGGCGTGAGTGGGTCGGTGGCGCGCGC
GTTCGCCCGGGACGGGTACG

Product: GCN5-like N-acetyltransferase

Products: NA

Alternate protein names: AAC(2')-Ic [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MIVRCGTDELSAVELVETRALLDAAFTDFSDHDWSHALGGVHALAVEEGRVLAHGSVVPRRLLQGGHPLHCGYVEAVAVR
PDVQRRGLGSAVMTALEDLAPAYDLLALSASARGVPLYRARGWSLWRGPSSVLTLDGPVPTPDDDGSIYVLPGASGVDLD
GPITCDWRDGDVW

Sequences:

>Translated_173_residues
MIVRCGTDELSAVELVETRALLDAAFTDFSDHDWSHALGGVHALAVEEGRVLAHGSVVPRRLLQGGHPLHCGYVEAVAVR
PDVQRRGLGSAVMTALEDLAPAYDLLALSASARGVPLYRARGWSLWRGPSSVLTLDGPVPTPDDDGSIYVLPGASGVDLD
GPITCDWRDGDVW
>Mature_173_residues
MIVRCGTDELSAVELVETRALLDAAFTDFSDHDWSHALGGVHALAVEEGRVLAHGSVVPRRLLQGGHPLHCGYVEAVAVR
PDVQRRGLGSAVMTALEDLAPAYDLLALSASARGVPLYRARGWSLWRGPSSVLTLDGPVPTPDDDGSIYVLPGASGVDLD
GPITCDWRDGDVW

Specific function: Catalyzes the coenzyme A-dependent acetylation of the 2' hydroxyl or amino group of a broad spectrum of aminoglycosides. It confers resistance to aminoglycosides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: NA

Molecular weight: Translated: 18406; Mature: 18406

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRCGTDELSAVELVETRALLDAAFTDFSDHDWSHALGGVHALAVEEGRVLAHGSVVPR
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEEEECCEEEEECCHHHH
RLLQGGHPLHCGYVEAVAVRPDVQRRGLGSAVMTALEDLAPAYDLLALSASARGVPLYRA
HHHCCCCCEECCEEEEEEECCCHHHCCCCHHHHHHHHHHCCHHHHHEECCCCCCCEEEEC
RGWSLWRGPSSVLTLDGPVPTPDDDGSIYVLPGASGVDLDGPITCDWRDGDVW
CCCEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MIVRCGTDELSAVELVETRALLDAAFTDFSDHDWSHALGGVHALAVEEGRVLAHGSVVPR
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEEEECCEEEEECCHHHH
RLLQGGHPLHCGYVEAVAVRPDVQRRGLGSAVMTALEDLAPAYDLLALSASARGVPLYRA
HHHCCCCCEECCEEEEEEECCCHHHCCCCHHHHHHHHHHCCHHHHHEECCCCCCCEEEEC
RGWSLWRGPSSVLTLDGPVPTPDDDGSIYVLPGASGVDLDGPITCDWRDGDVW
CCCEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]