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The map label for this gene is ffh [H]

Identifier: 119717490

GI number: 119717490

Start: 3467498

End: 3469069

Strand: Reverse

Name: ffh [H]

Synonym: Noca_3266

Alternate gene names: 119717490

Gene position: 3469069-3467498 (Counterclockwise)

Preceding gene: 119717491

Following gene: 119717489

Centisome position: 69.58

GC content: 69.85

Gene sequence:

>1572_bases
TTGTTCGCCACACTCTCCGACCGGCTCGCCGACACCTTCAAGAACCTCCGGGGGAAGGGTCGGCTCTCCGAGGCCGACAT
CGACGCCACCGCGCGCGAGATCCGGATCGCCCTGCTCGAGGCCGACGTCGCGCTGCCGGTGGTCAAGGAGTTCGTCGGCG
CCGTCAAGGAGCGCGCTCGCGGCGAGGAGGTCAGCCAGGCGCTGAACCCGGCCCAGCAGGTCGTCAAGATCGTCAACGAG
GAGCTCGTGGCGATCCTCGGCGGGGAGGCTCGGCGGCTGCGCTACGCCAAGACCGGCCCGACGGTCATCATGCTCGCCGG
CCTCCAGGGCGCCGGCAAGACGACGCTGGCGGCCAAGCTCGCGCTCTGGCTCAAGGAGCAGGGCAAGAGCCCGCTGCTGG
TCGCCGCCGACCTCCAGCGCCCGAACGCGGTCAACCAGCTCCAGGTCAACGGCGAACGCGCCGGCGTACCCGTCTTCGCG
CCCGAGCCCGGGAACGGCGTCGGGGACCCGGTCGGCGTGGCCCGGGCCTCGATCGAGGAGGCCAAGCGCACCCTCCACGA
CGTGGTCATCGTCGACACCGCCGGCCGCCTCGGCGTCGACGCCGAGATGATGCAACAGGCCGCGGACATCCGCGACGCGG
TCCAGCCCGACGAGGTGCTCTTCGTCGTCGACGCGATGATCGGCCAGGACGCCGTCGTGACGGCGCAGGCGTTCCTCGAC
GGCGTCGGGTACGACGGCGTGGTGCTCACCAAGCTCGACGGTGACGCCCGCGGTGGCGCCGCGCTGTCGATCGCCTCGAT
CACCGGCAAGCCGGTGATGTTCGCGTCGGCCGGCGAGAAGCTCACCGACTTCGACCTCTTCCACCCCGACCGGATGGCCT
CGCGGATCCTCGACATGGGTGACGTGATGACCCTGATCGAGCAGGCCGAGAAGGCCTTCGACCAGGAGCAGGCCGCGAAG
GCCGCGGCCAAGCTCACCGGGCAGGGCGGCGAGTTCACCCTCGACGACTTCCTCGAGCAGATGCAGCAGGTCCGCAAGCT
CGGCTCGATGTCGAAGATCATGGGGATGCTTCCCGGGATGGGGCAGTTCCGCGAGCAGCTGGAGAACTTCGATGAGCGCG
AGATCGACCGGATCCAGGCGATCATCCAGTCGATGACTCCGGCCGAGCGGGCGAACCCGAAGATCATCGACGGCTCCCGC
CGGGCCCGCATCGCGCGAGGCTCGGGACGCCAGGTCTCCGACGTCAACCAGCTCGTGGACCGGTTCTTCGAGGCCCGCAA
GATGATGATGTCGCTGGCCAAGGGCGGCGGGATGCCGGGGATGCCCGGGATGGCCGGGATGCCGGGGATGGGCAAGCGAG
CCAAGGCCAAGCAGGCCCCGAAGAAGGGCAAGGGGGGCAAGCGGGTCTCCGGCAACCCTGCCAAGGCAGCCCAGCAGGCC
GCGGCCGCGAAGGAGAAGGCCCAGGGCGCGCCCGCCAACCCGTTCGGGACCCCCGACGGGGAGGAGCTGGACTATGAGAA
GGCGGCGGCCGCCCTCAACCTGCCCAAGGACTTCTCCAAGTTCCTCAAATAG

Upstream 100 bases:

>100_bases
ACTCCTGAGGCGGCCCGGCCCGGGGACGATGCGCCCGCCTGCGGGGCCGCCGTCTAGGCTGAACCCGCCAGATCAGCCGC
CAAGCCCGTAGGACGCACCC

Downstream 100 bases:

>100_bases
TCGCTACGCGACTAGGAACTGCGTCGTGGTCGCTTCGCTCCCCGCCCTTTCGTTCCGCCGAACCAGGCTCGCTGCGCTCG
CGGTTCGACGCGCGACTAGG

Product: signal recognition particle subunit FFH/SRP54 (srp54)

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MFATLSDRLADTFKNLRGKGRLSEADIDATAREIRIALLEADVALPVVKEFVGAVKERARGEEVSQALNPAQQVVKIVNE
ELVAILGGEARRLRYAKTGPTVIMLAGLQGAGKTTLAAKLALWLKEQGKSPLLVAADLQRPNAVNQLQVNGERAGVPVFA
PEPGNGVGDPVGVARASIEEAKRTLHDVVIVDTAGRLGVDAEMMQQAADIRDAVQPDEVLFVVDAMIGQDAVVTAQAFLD
GVGYDGVVLTKLDGDARGGAALSIASITGKPVMFASAGEKLTDFDLFHPDRMASRILDMGDVMTLIEQAEKAFDQEQAAK
AAAKLTGQGGEFTLDDFLEQMQQVRKLGSMSKIMGMLPGMGQFREQLENFDEREIDRIQAIIQSMTPAERANPKIIDGSR
RARIARGSGRQVSDVNQLVDRFFEARKMMMSLAKGGGMPGMPGMAGMPGMGKRAKAKQAPKKGKGGKRVSGNPAKAAQQA
AAAKEKAQGAPANPFGTPDGEELDYEKAAAALNLPKDFSKFLK

Sequences:

>Translated_523_residues
MFATLSDRLADTFKNLRGKGRLSEADIDATAREIRIALLEADVALPVVKEFVGAVKERARGEEVSQALNPAQQVVKIVNE
ELVAILGGEARRLRYAKTGPTVIMLAGLQGAGKTTLAAKLALWLKEQGKSPLLVAADLQRPNAVNQLQVNGERAGVPVFA
PEPGNGVGDPVGVARASIEEAKRTLHDVVIVDTAGRLGVDAEMMQQAADIRDAVQPDEVLFVVDAMIGQDAVVTAQAFLD
GVGYDGVVLTKLDGDARGGAALSIASITGKPVMFASAGEKLTDFDLFHPDRMASRILDMGDVMTLIEQAEKAFDQEQAAK
AAAKLTGQGGEFTLDDFLEQMQQVRKLGSMSKIMGMLPGMGQFREQLENFDEREIDRIQAIIQSMTPAERANPKIIDGSR
RARIARGSGRQVSDVNQLVDRFFEARKMMMSLAKGGGMPGMPGMAGMPGMGKRAKAKQAPKKGKGGKRVSGNPAKAAQQA
AAAKEKAQGAPANPFGTPDGEELDYEKAAAALNLPKDFSKFLK
>Mature_523_residues
MFATLSDRLADTFKNLRGKGRLSEADIDATAREIRIALLEADVALPVVKEFVGAVKERARGEEVSQALNPAQQVVKIVNE
ELVAILGGEARRLRYAKTGPTVIMLAGLQGAGKTTLAAKLALWLKEQGKSPLLVAADLQRPNAVNQLQVNGERAGVPVFA
PEPGNGVGDPVGVARASIEEAKRTLHDVVIVDTAGRLGVDAEMMQQAADIRDAVQPDEVLFVVDAMIGQDAVVTAQAFLD
GVGYDGVVLTKLDGDARGGAALSIASITGKPVMFASAGEKLTDFDLFHPDRMASRILDMGDVMTLIEQAEKAFDQEQAAK
AAAKLTGQGGEFTLDDFLEQMQQVRKLGSMSKIMGMLPGMGQFREQLENFDEREIDRIQAIIQSMTPAERANPKIIDGSR
RARIARGSGRQVSDVNQLVDRFFEARKMMMSLAKGGGMPGMPGMAGMPGMGKRAKAKQAPKKGKGGKRVSGNPAKAAQQA
AAAKEKAQGAPANPFGTPDGEELDYEKAAAALNLPKDFSKFLK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=454, Percent_Identity=32.8193832599119, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI226371618, Length=393, Percent_Identity=33.587786259542, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI23308697, Length=303, Percent_Identity=32.013201320132, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI295424842, Length=303, Percent_Identity=32.013201320132, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI89061728, Length=143, Percent_Identity=37.7622377622378, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788963, Length=424, Percent_Identity=51.8867924528302, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1789874, Length=301, Percent_Identity=35.2159468438538, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17539958, Length=412, Percent_Identity=33.252427184466, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI193206261, Length=295, Percent_Identity=32.5423728813559, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=452, Percent_Identity=32.0796460176991, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6320498, Length=317, Percent_Identity=26.4984227129338, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17647949, Length=363, Percent_Identity=32.7823691460055, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24641198, Length=307, Percent_Identity=30.9446254071661, Blast_Score=119, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 55703; Mature: 55703

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFATLSDRLADTFKNLRGKGRLSEADIDATAREIRIALLEADVALPVVKEFVGAVKERAR
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEEVSQALNPAQQVVKIVNEELVAILGGEARRLRYAKTGPTVIMLAGLQGAGKTTLAAKL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCEEEEECCCCCCCHHHHHHH
ALWLKEQGKSPLLVAADLQRPNAVNQLQVNGERAGVPVFAPEPGNGVGDPVGVARASIEE
HHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHH
AKRTLHDVVIVDTAGRLGVDAEMMQQAADIRDAVQPDEVLFVVDAMIGQDAVVTAQAFLD
HHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHCCCHHHHHHHHHC
GVGYDGVVLTKLDGDARGGAALSIASITGKPVMFASAGEKLTDFDLFHPDRMASRILDMG
CCCCCCEEEEEECCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
DVMTLIEQAEKAFDQEQAAKAAAKLTGQGGEFTLDDFLEQMQQVRKLGSMSKIMGMLPGM
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
GQFREQLENFDEREIDRIQAIIQSMTPAERANPKIIDGSRRARIARGSGRQVSDVNQLVD
HHHHHHHHCCCHHHHHHHHHHHHHCCCHHHCCCCEECCCCHHEEECCCCCCHHHHHHHHH
RFFEARKMMMSLAKGGGMPGMPGMAGMPGMGKRAKAKQAPKKGKGGKRVSGNPAKAAQQA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHH
AAAKEKAQGAPANPFGTPDGEELDYEKAAAALNLPKDFSKFLK
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MFATLSDRLADTFKNLRGKGRLSEADIDATAREIRIALLEADVALPVVKEFVGAVKERAR
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEEVSQALNPAQQVVKIVNEELVAILGGEARRLRYAKTGPTVIMLAGLQGAGKTTLAAKL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCEEEEECCCCCCCHHHHHHH
ALWLKEQGKSPLLVAADLQRPNAVNQLQVNGERAGVPVFAPEPGNGVGDPVGVARASIEE
HHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHH
AKRTLHDVVIVDTAGRLGVDAEMMQQAADIRDAVQPDEVLFVVDAMIGQDAVVTAQAFLD
HHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHCCCHHHHHHHHHC
GVGYDGVVLTKLDGDARGGAALSIASITGKPVMFASAGEKLTDFDLFHPDRMASRILDMG
CCCCCCEEEEEECCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
DVMTLIEQAEKAFDQEQAAKAAAKLTGQGGEFTLDDFLEQMQQVRKLGSMSKIMGMLPGM
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
GQFREQLENFDEREIDRIQAIIQSMTPAERANPKIIDGSRRARIARGSGRQVSDVNQLVD
HHHHHHHHCCCHHHHHHHHHHHHHCCCHHHCCCCEECCCCHHEEECCCCCCHHHHHHHHH
RFFEARKMMMSLAKGGGMPGMPGMAGMPGMGKRAKAKQAPKKGKGGKRVSGNPAKAAQQA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHH
AAAKEKAQGAPANPFGTPDGEELDYEKAAAALNLPKDFSKFLK
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]