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The map label for this gene is hsaB [H]

Identifier: 119716997

GI number: 119716997

Start: 2944317

End: 2944931

Strand: Reverse

Name: hsaB [H]

Synonym: Noca_2773

Alternate gene names: 119716997

Gene position: 2944931-2944317 (Counterclockwise)

Preceding gene: 119716998

Following gene: 119716991

Centisome position: 59.07

GC content: 71.87

Gene sequence:

>615_bases
ATGAGCCCGGACGCGCGCGAGACCTGGCCGAGCCCGGAGCTGATCAGCTCGTGGCTCGGCGACCAGGACATCGACTTCGA
GTTCCGTCCCGGCGAGGACGTCGCCGTCCGCGACGACCCCGAGACCATGGCGGCGGCCCGGCGGTTCCGCGACGTGCTCG
GCCGGTTCGGCTCCGGCGTCACCGTCGTCACCGGGATCAGCGGCGACGAGCCGGTCGGCCTGACCTGCCAGTCGTTCTCG
AGCGTCTCCCTGGACCCGCCGCTGGTGCTGTTCATCCCCGCCAAGACCTCGCGGGCCTGGCCGCTGATCCAGCGCTCGGG
CAAGTTCTGCGTGAACTTCCTCGCCGCGGACCAGGCCGAGCTCTCGAACACGATGGCCAGCCGCGGCGCCGACAAGTTCG
CGGACGTGAAGTGGACCCCGTCGCCGGGCACCGGGTCGCCGATGCTCGAGGGCGCCCTGGCCCACGTCGACTGCACGATC
CACCAGGTGCACGCGGCCGGCGACCACTACATCGTGATCGGGCGCGTGATCGACCTGATCACCGACGACGACGCCGCCGC
GGTCGGCCCGCTGCTGTTCTACCGCGGCGAGTACCGCGGCACCGACCGCCGCTGA

Upstream 100 bases:

>100_bases
CTTCGGCGCGGCGGCCGGGTGAGCGATGCCCAGCGATTTCGGGAGCAGTGAGAAACTCGACCACATGACCTCCGAGCCGA
GCCGTGAGATCCCGGAGGGC

Downstream 100 bases:

>100_bases
CCCGGCTGCTAGGACCGCCTGCTAGGACCGGCCCTCCGGCGGGGCGACGTTGACGGTGGGCGTCCCGCCGCCGGCCCGGA
CGATCACCGCGAGCGACGGC

Product: flavin reductase domain-containing protein

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSPDARETWPSPELISSWLGDQDIDFEFRPGEDVAVRDDPETMAAARRFRDVLGRFGSGVTVVTGISGDEPVGLTCQSFS
SVSLDPPLVLFIPAKTSRAWPLIQRSGKFCVNFLAADQAELSNTMASRGADKFADVKWTPSPGTGSPMLEGALAHVDCTI
HQVHAAGDHYIVIGRVIDLITDDDAAAVGPLLFYRGEYRGTDRR

Sequences:

>Translated_204_residues
MSPDARETWPSPELISSWLGDQDIDFEFRPGEDVAVRDDPETMAAARRFRDVLGRFGSGVTVVTGISGDEPVGLTCQSFS
SVSLDPPLVLFIPAKTSRAWPLIQRSGKFCVNFLAADQAELSNTMASRGADKFADVKWTPSPGTGSPMLEGALAHVDCTI
HQVHAAGDHYIVIGRVIDLITDDDAAAVGPLLFYRGEYRGTDRR
>Mature_203_residues
SPDARETWPSPELISSWLGDQDIDFEFRPGEDVAVRDDPETMAAARRFRDVLGRFGSGVTVVTGISGDEPVGLTCQSFSS
VSLDPPLVLFIPAKTSRAWPLIQRSGKFCVNFLAADQAELSNTMASRGADKFADVKWTPSPGTGSPMLEGALAHVDCTIH
QVHAAGDHYIVIGRVIDLITDDDAAAVGPLLFYRGEYRGTDRR

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

Organism=Escherichia coli, GI87081819, Length=132, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 22125; Mature: 21994

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDARETWPSPELISSWLGDQDIDFEFRPGEDVAVRDDPETMAAARRFRDVLGRFGSGV
CCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCCEECCCHHHHHHHHHHHHHHHHHCCCE
TVVTGISGDEPVGLTCQSFSSVSLDPPLVLFIPAKTSRAWPLIQRSGKFCVNFLAADQAE
EEEEECCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCCCHHHHCCCCCEEHHHHHCHHH
LSNTMASRGADKFADVKWTPSPGTGSPMLEGALAHVDCTIHQVHAAGDHYIVIGRVIDLI
HHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHEEEEEEEEECCCCCEEEEEEEEHHH
TDDDAAAVGPLLFYRGEYRGTDRR
CCCCCHHHHHHEEECCCCCCCCCC
>Mature Secondary Structure 
SPDARETWPSPELISSWLGDQDIDFEFRPGEDVAVRDDPETMAAARRFRDVLGRFGSGV
CCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCCEECCCHHHHHHHHHHHHHHHHHCCCE
TVVTGISGDEPVGLTCQSFSSVSLDPPLVLFIPAKTSRAWPLIQRSGKFCVNFLAADQAE
EEEEECCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCCCHHHHCCCCCEEHHHHHCHHH
LSNTMASRGADKFADVKWTPSPGTGSPMLEGALAHVDCTIHQVHAAGDHYIVIGRVIDLI
HHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHEEEEEEEEECCCCCEEEEEEEEHHH
TDDDAAAVGPLLFYRGEYRGTDRR
CCCCCHHHHHHEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA