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The map label for this gene is fadE25 [H]

Identifier: 119716991

GI number: 119716991

Start: 2937930

End: 2939066

Strand: Reverse

Name: fadE25 [H]

Synonym: Noca_2767

Alternate gene names: 119716991

Gene position: 2939066-2937930 (Counterclockwise)

Preceding gene: 119716997

Following gene: 119716990

Centisome position: 58.95

GC content: 73.09

Gene sequence:

>1137_bases
GTGCGGGGCTGGCTCGAGGAGCACCTGACCGGCGAGTGGGCCGCGCTCAAGGGGCTCGGCGGCGCCGGCCGCGACCACGA
GGCGCACGAGGAACGGGTGGCCTGGAACCGGCTGCTCGCCGAGCACGGCTGGACCTGCCTGGGCTGGCCGACCGAGCACG
GCGGGCGCGGGCTGAGCCTGGTCCAGCAGGTGATCTTCCACGAGGAGTACGCACGCGCCGACGCGCCGGGACGGGTGAAC
CATCTCGGCGAGGAGCTGCTCGGACCGACCCTGATCGCGTTCGGCACGCCCGAGCAGCAGCAGCGGTTCCTGCCGCGGAT
CGTGGCGGTCGAGGACCTGTGGGCGCAGGGCTACTCCGAGCCCGACGCCGGCTCCGACCTCGCCAACGTGCAGACCAAGG
CACGACTCGTCGGCGACGAGTGGGTGATCGACGGGCAGAAGGTGTGGACGTCGAACGCCCACCTCAGCCAGTGGGCGTTC
GTCGTCTGCCGCACCGTGCCGGGGTCCACGCGCCACCACGGGCTGTCGTTCCTGCTCGTGCCGCTGGAGCAGGACGGCGT
GGAGATCCGGCCGATCGAGCAGCTCACCGGCGGGTCGGAGTTCAACGAGGTCTTCTTCACCGGGGCCCGGACCGCCGCCG
ACCTGGTCGTGGGGGAGCCCGGCGGCGGCTGGCGGGTCGCGATGGCGCTGCTCGGCTTCGAGCGCGGGGTGTCCGTGCTC
GGTCAGGTGGTCGGCTTCGCTCGCGAGCTGTCCGGTGTCGTGGACCTCGCGCGAGAGACCGGTGCGATCGACGACCCGGT
GCTCCGCGACCGGCTGGCCGCGCTGAAGGTCGAGCTCGAGGTGATGCGGTTCCAGGCGCTGCGCGGGCTCGCGTCGAACG
ACGCCGGCAGCGCCTCGGTCTTCAAGCTCGTCTGGGCGGGCTGGCACCGGCGGCTCGGCGAGGTCGCGATGGACGTCGCC
GGCGCGGGCGGGCTGACCGCGCTGCCGGGCTCCCCGGAGGCGCCGTACCAGCTGGACCGCTGGCAGCGGCTCTTCCTGTT
CTCGCGCGCCGACACGATCTACGGCGGCAGCGACGAGGTCCAGCGCAACATCCTCGCCGAGCGGGTGCTCGGCCTACCGA
AGGAGGCTCGCGGATGA

Upstream 100 bases:

>100_bases
CCTGCATCGCCACCTCCGTCAGCCAACCAAGCAATTGCTTGGTAGACTACCACTCGTGGACCTGACCTACTCCCCGGCCG
ACCAGGCCTTCCGCGCGGAG

Downstream 100 bases:

>100_bases
CCGCTCCCGCCTACGTCCCCGGCCACGACCTGCTCGCCGGGAAGGTGGTCGTCGTGACCGCCGCCGCCGGCGCGGGCATC
GGCGCCGCCGTCGTACGCCG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MRGWLEEHLTGEWAALKGLGGAGRDHEAHEERVAWNRLLAEHGWTCLGWPTEHGGRGLSLVQQVIFHEEYARADAPGRVN
HLGEELLGPTLIAFGTPEQQQRFLPRIVAVEDLWAQGYSEPDAGSDLANVQTKARLVGDEWVIDGQKVWTSNAHLSQWAF
VVCRTVPGSTRHHGLSFLLVPLEQDGVEIRPIEQLTGGSEFNEVFFTGARTAADLVVGEPGGGWRVAMALLGFERGVSVL
GQVVGFARELSGVVDLARETGAIDDPVLRDRLAALKVELEVMRFQALRGLASNDAGSASVFKLVWAGWHRRLGEVAMDVA
GAGGLTALPGSPEAPYQLDRWQRLFLFSRADTIYGGSDEVQRNILAERVLGLPKEARG

Sequences:

>Translated_378_residues
MRGWLEEHLTGEWAALKGLGGAGRDHEAHEERVAWNRLLAEHGWTCLGWPTEHGGRGLSLVQQVIFHEEYARADAPGRVN
HLGEELLGPTLIAFGTPEQQQRFLPRIVAVEDLWAQGYSEPDAGSDLANVQTKARLVGDEWVIDGQKVWTSNAHLSQWAF
VVCRTVPGSTRHHGLSFLLVPLEQDGVEIRPIEQLTGGSEFNEVFFTGARTAADLVVGEPGGGWRVAMALLGFERGVSVL
GQVVGFARELSGVVDLARETGAIDDPVLRDRLAALKVELEVMRFQALRGLASNDAGSASVFKLVWAGWHRRLGEVAMDVA
GAGGLTALPGSPEAPYQLDRWQRLFLFSRADTIYGGSDEVQRNILAERVLGLPKEARG
>Mature_378_residues
MRGWLEEHLTGEWAALKGLGGAGRDHEAHEERVAWNRLLAEHGWTCLGWPTEHGGRGLSLVQQVIFHEEYARADAPGRVN
HLGEELLGPTLIAFGTPEQQQRFLPRIVAVEDLWAQGYSEPDAGSDLANVQTKARLVGDEWVIDGQKVWTSNAHLSQWAF
VVCRTVPGSTRHHGLSFLLVPLEQDGVEIRPIEQLTGGSEFNEVFFTGARTAADLVVGEPGGGWRVAMALLGFERGVSVL
GQVVGFARELSGVVDLARETGAIDDPVLRDRLAALKVELEVMRFQALRGLASNDAGSASVFKLVWAGWHRRLGEVAMDVA
GAGGLTALPGSPEAPYQLDRWQRLFLFSRADTIYGGSDEVQRNILAERVLGLPKEARG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=344, Percent_Identity=28.7790697674419, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI187960098, Length=331, Percent_Identity=25.6797583081571, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4557231, Length=331, Percent_Identity=25.6797583081571, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4501857, Length=335, Percent_Identity=26.5671641791045, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226958412, Length=244, Percent_Identity=27.4590163934426, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI226958414, Length=217, Percent_Identity=27.6497695852535, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4557235, Length=226, Percent_Identity=29.2035398230088, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI76496475, Length=226, Percent_Identity=29.2035398230088, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI4501859, Length=328, Percent_Identity=25.3048780487805, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI48976061, Length=300, Percent_Identity=28.6666666666667, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI211971008, Length=300, Percent_Identity=28.6666666666667, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI21361497, Length=211, Percent_Identity=29.8578199052133, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI87081958, Length=347, Percent_Identity=23.6311239193084, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=346, Percent_Identity=26.878612716763, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=342, Percent_Identity=26.9005847953216, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=228, Percent_Identity=26.7543859649123, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=331, Percent_Identity=25.9818731117825, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17505929, Length=228, Percent_Identity=27.6315789473684, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=340, Percent_Identity=25.2941176470588, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17506239, Length=212, Percent_Identity=30.6603773584906, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=210, Percent_Identity=30.4761904761905, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=203, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=251, Percent_Identity=26.2948207171315, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=367, Percent_Identity=26.158038147139, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=205, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71985184, Length=145, Percent_Identity=32.4137931034483, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71985192, Length=146, Percent_Identity=32.1917808219178, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356377, Length=392, Percent_Identity=25.765306122449, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24646207, Length=347, Percent_Identity=26.8011527377522, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24660351, Length=335, Percent_Identity=26.2686567164179, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355753, Length=278, Percent_Identity=27.6978417266187, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24666513, Length=253, Percent_Identity=24.901185770751, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281363737, Length=202, Percent_Identity=30.1980198019802, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41271; Mature: 41271

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGWLEEHLTGEWAALKGLGGAGRDHEAHEERVAWNRLLAEHGWTCLGWPTEHGGRGLSL
CCCHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHH
VQQVIFHEEYARADAPGRVNHLGEELLGPTLIAFGTPEQQQRFLPRIVAVEDLWAQGYSE
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
PDAGSDLANVQTKARLVGDEWVIDGQKVWTSNAHLSQWAFVVCRTVPGSTRHHGLSFLLV
CCCCCHHHHHHHHHHEECCCEEECCCCEECCCCCHHHHHHHEEECCCCCCCCCCEEEEEE
PLEQDGVEIRPIEQLTGGSEFNEVFFTGARTAADLVVGEPGGGWRVAMALLGFERGVSVL
EECCCCCEEEEHHHHCCCCCCCHHEEECCCHHHHEEEECCCCCHHHHHHHHHHHHHHHHH
GQVVGFARELSGVVDLARETGAIDDPVLRDRLAALKVELEVMRFQALRGLASNDAGSASV
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
FKLVWAGWHRRLGEVAMDVAGAGGLTALPGSPEAPYQLDRWQRLFLFSRADTIYGGSDEV
HHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH
QRNILAERVLGLPKEARG
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRGWLEEHLTGEWAALKGLGGAGRDHEAHEERVAWNRLLAEHGWTCLGWPTEHGGRGLSL
CCCHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHH
VQQVIFHEEYARADAPGRVNHLGEELLGPTLIAFGTPEQQQRFLPRIVAVEDLWAQGYSE
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
PDAGSDLANVQTKARLVGDEWVIDGQKVWTSNAHLSQWAFVVCRTVPGSTRHHGLSFLLV
CCCCCHHHHHHHHHHEECCCEEECCCCEECCCCCHHHHHHHEEECCCCCCCCCCEEEEEE
PLEQDGVEIRPIEQLTGGSEFNEVFFTGARTAADLVVGEPGGGWRVAMALLGFERGVSVL
EECCCCCEEEEHHHHCCCCCCCHHEEECCCHHHHEEEECCCCCHHHHHHHHHHHHHHHHH
GQVVGFARELSGVVDLARETGAIDDPVLRDRLAALKVELEVMRFQALRGLASNDAGSASV
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
FKLVWAGWHRRLGEVAMDVAGAGGLTALPGSPEAPYQLDRWQRLFLFSRADTIYGGSDEV
HHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH
QRNILAERVLGLPKEARG
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]