| Definition | Nocardioides sp. JS614 chromosome, complete genome. |
|---|---|
| Accession | NC_008699 |
| Length | 4,985,871 |
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The map label for this gene is fabG2 [H]
Identifier: 119716990
GI number: 119716990
Start: 2937151
End: 2937933
Strand: Reverse
Name: fabG2 [H]
Synonym: Noca_2766
Alternate gene names: 119716990
Gene position: 2937933-2937151 (Counterclockwise)
Preceding gene: 119716991
Following gene: 119716989
Centisome position: 58.93
GC content: 73.31
Gene sequence:
>783_bases ATGACCGCTCCCGCCTACGTCCCCGGCCACGACCTGCTCGCCGGGAAGGTGGTCGTCGTGACCGCCGCCGCCGGCGCGGG CATCGGCGCCGCCGTCGTACGCCGCGTGCTCGAGGAGGGCGCGAAGGCGGTGGTGTTCAGCGACACCCACGAGCGCCGGC TCGCCGAGGCGGAGGAGGCGCTGGCGGGGGAGTTCGGCCGCGACCGGGTCCGCCAGCTGGTCTGCGACGTCACCGACGAG GCGCAGGTGCAGGTGCTGCTGGACGCGGCCGAGGATCTCGGCGGCGTCGACGTGATGGTCAACAACGCCGGCCTGGGTGG CACGGCGAGCGTGCTGGAGATGACCGACGAGCAGTGGTCGCGGGTCCTCGACATCACGCTGACCGGGACCTTCCGGTGCG TGCGCGCCGCCGGGCAGCGGATGACGGCGTCCGGTCGTGCCGGCGTGATCGTCAACAACGCCTCGGTGATCGGCTGGCGC GCCCAGGAGGGCCAGGCGCACTACGCCGCCGCCAAGGCGGGGGTGATGGCGCTGACCCGGTGCGCGGCGCTCGACCTGGC TCCGCACGGCATCCGGGTCAACGCCGTGGCGCCGAGCCTGGCGATGCACCCGTTCCTGGCGAAGGTCACCTCCGACGAGC TGCTCGCCGAGCTCACGGGCCGCGAGGCGTTCGGCCGGGCCGCGGAGCCGTGGGAGGTCGCCAACGTGATGGTGTTCCTG GCGAGCGACTACTCGTCGTACCTGACCGGCGAGGTCGTCTCCGTGAGCAGTCAGCGAGGCTAG
Upstream 100 bases:
>100_bases TCCTGTTCTCGCGCGCCGACACGATCTACGGCGGCAGCGACGAGGTCCAGCGCAACATCCTCGCCGAGCGGGTGCTCGGC CTACCGAAGGAGGCTCGCGG
Downstream 100 bases:
>100_bases GGACATGTCCGCCCAGAAGTCCGTGCAGAAGTCCGCGCAGAAGACGCCCGAGTCCGAGGCTCCGCACACCCGTCGTGCCC AGCTGCTGCAGATCGCCGCC
Product: short chain dehydrogenase
Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+
Alternate protein names: NA
Number of amino acids: Translated: 260; Mature: 259
Protein sequence:
>260_residues MTAPAYVPGHDLLAGKVVVVTAAAGAGIGAAVVRRVLEEGAKAVVFSDTHERRLAEAEEALAGEFGRDRVRQLVCDVTDE AQVQVLLDAAEDLGGVDVMVNNAGLGGTASVLEMTDEQWSRVLDITLTGTFRCVRAAGQRMTASGRAGVIVNNASVIGWR AQEGQAHYAAAKAGVMALTRCAALDLAPHGIRVNAVAPSLAMHPFLAKVTSDELLAELTGREAFGRAAEPWEVANVMVFL ASDYSSYLTGEVVSVSSQRG
Sequences:
>Translated_260_residues MTAPAYVPGHDLLAGKVVVVTAAAGAGIGAAVVRRVLEEGAKAVVFSDTHERRLAEAEEALAGEFGRDRVRQLVCDVTDE AQVQVLLDAAEDLGGVDVMVNNAGLGGTASVLEMTDEQWSRVLDITLTGTFRCVRAAGQRMTASGRAGVIVNNASVIGWR AQEGQAHYAAAKAGVMALTRCAALDLAPHGIRVNAVAPSLAMHPFLAKVTSDELLAELTGREAFGRAAEPWEVANVMVFL ASDYSSYLTGEVVSVSSQRG >Mature_259_residues TAPAYVPGHDLLAGKVVVVTAAAGAGIGAAVVRRVLEEGAKAVVFSDTHERRLAEAEEALAGEFGRDRVRQLVCDVTDEA QVQVLLDAAEDLGGVDVMVNNAGLGGTASVLEMTDEQWSRVLDITLTGTFRCVRAAGQRMTASGRAGVIVNNASVIGWRA QEGQAHYAAAKAGVMALTRCAALDLAPHGIRVNAVAPSLAMHPFLAKVTSDELLAELTGREAFGRAAEPWEVANVMVFLA SDYSSYLTGEVVSVSSQRG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=240, Percent_Identity=33.75, Blast_Score=115, Evalue=5e-26, Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=34.5238095238095, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=33.2, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=32.8301886792453, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=31.496062992126, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=31.4285714285714, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI40254992, Length=230, Percent_Identity=33.0434782608696, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=30.9236947791165, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI83715985, Length=252, Percent_Identity=32.1428571428571, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=29.8387096774194, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI31542939, Length=260, Percent_Identity=26.9230769230769, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=31.5555555555556, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=32.0158102766798, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI4504505, Length=191, Percent_Identity=31.9371727748691, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI33667109, Length=214, Percent_Identity=30.3738317757009, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=31.7460317460317, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI4503301, Length=221, Percent_Identity=25.7918552036199, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=34.156378600823, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=35.3413654618474, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=32.2448979591837, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=29.3650793650794, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=30.5555555555556, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1788459, Length=163, Percent_Identity=33.1288343558282, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI2367175, Length=240, Percent_Identity=32.0833333333333, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=30, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1789057, Length=251, Percent_Identity=26.2948207171315, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=31.4741035856574, Blast_Score=77, Evalue=9e-16, Organism=Escherichia coli, GI1789378, Length=233, Percent_Identity=28.755364806867, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=5e-15, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=34.5528455284553, Blast_Score=127, Evalue=7e-30, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=8e-28, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=31.3253012048193, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17560150, Length=256, Percent_Identity=30.078125, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=29.1828793774319, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=27.1653543307087, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=29.0196078431373, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17559104, Length=253, Percent_Identity=32.8063241106719, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI71994604, Length=220, Percent_Identity=30.4545454545455, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI71994600, Length=188, Percent_Identity=29.7872340425532, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562904, Length=257, Percent_Identity=28.7937743190661, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=28.4644194756554, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=32.046332046332, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=26.9961977186312, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=26.9961977186312, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=29.0196078431373, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=26.9961977186312, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=26.953125, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=26.4, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=27.9527559055118, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=27.2030651340996, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17561272, Length=187, Percent_Identity=28.8770053475936, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17538486, Length=255, Percent_Identity=27.4509803921569, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=26.5384615384615, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=27.8350515463918, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=26.0536398467433, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=29.8449612403101, Blast_Score=68, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=218, Percent_Identity=31.651376146789, Blast_Score=91, Evalue=1e-19, Organism=Saccharomyces cerevisiae, GI6324126, Length=265, Percent_Identity=27.1698113207547, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=28.4263959390863, Blast_Score=62, Evalue=9e-11, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=35.6, Blast_Score=125, Evalue=3e-29, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=33.6, Blast_Score=107, Evalue=9e-24, Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=32.8125, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=31.4285714285714, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.6, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=32.6848249027237, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=30.6451612903226, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24643142, Length=240, Percent_Identity=29.5833333333333, Blast_Score=84, Evalue=8e-17, Organism=Drosophila melanogaster, GI18859837, Length=243, Percent_Identity=29.6296296296296, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24644337, Length=167, Percent_Identity=33.5329341317365, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI116007236, Length=193, Percent_Identity=28.4974093264249, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI116007238, Length=239, Percent_Identity=25.5230125523013, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24663911, Length=193, Percent_Identity=31.6062176165803, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI28571387, Length=190, Percent_Identity=30, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24584752, Length=177, Percent_Identity=26.5536723163842, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI281364494, Length=194, Percent_Identity=30.4123711340206, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100
Molecular weight: Translated: 27174; Mature: 27043
Theoretical pI: Translated: 4.85; Mature: 4.85
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTAPAYVPGHDLLAGKVVVVTAAAGAGIGAAVVRRVLEEGAKAVVFSDTHERRLAEAEEA CCCCCCCCCCCHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH LAGEFGRDRVRQLVCDVTDEAQVQVLLDAAEDLGGVDVMVNNAGLGGTASVLEMTDEQWS HHCCCCHHHHHHHHHCCCCCHHEEEEEEHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHH RVLDITLTGTFRCVRAAGQRMTASGRAGVIVNNASVIGWRAQEGQAHYAAAKAGVMALTR EEEEEEEECHHHHHHHCCCEEECCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHH CAALDLAPHGIRVNAVAPSLAMHPFLAKVTSDELLAELTGREAFGRAAEPWEVANVMVFL HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHEEEEE ASDYSSYLTGEVVSVSSQRG ECCHHHHHCCCEEEECCCCC >Mature Secondary Structure TAPAYVPGHDLLAGKVVVVTAAAGAGIGAAVVRRVLEEGAKAVVFSDTHERRLAEAEEA CCCCCCCCCCHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH LAGEFGRDRVRQLVCDVTDEAQVQVLLDAAEDLGGVDVMVNNAGLGGTASVLEMTDEQWS HHCCCCHHHHHHHHHCCCCCHHEEEEEEHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHH RVLDITLTGTFRCVRAAGQRMTASGRAGVIVNNASVIGWRAQEGQAHYAAAKAGVMALTR EEEEEEEECHHHHHHHCCCEEECCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHH CAALDLAPHGIRVNAVAPSLAMHPFLAKVTSDELLAELTGREAFGRAAEPWEVANVMVFL HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHEEEEE ASDYSSYLTGEVVSVSSQRG ECCHHHHHCCCEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+
Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]