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The map label for this gene is clpP2 [H]

Identifier: 119716961

GI number: 119716961

Start: 2909633

End: 2910235

Strand: Reverse

Name: clpP2 [H]

Synonym: Noca_2736

Alternate gene names: 119716961

Gene position: 2910235-2909633 (Counterclockwise)

Preceding gene: 119716962

Following gene: 119716956

Centisome position: 58.37

GC content: 71.97

Gene sequence:

>603_bases
GTGAGCACCTACACCATCCCCAGCGTGGTCGAGCGGACCGCGCGCGGCGAGCGGGCCGTGGACATCTACAGCCGGCTGCT
GACCGACCGGATCGTGTACGTCGGCACCGAGATCGACGACGGGGTCGCCAACGTGGTCATCGCCCAGCTCCTCCACCTGG
AGTCCGACGCCCCGGACCAGCCGATCAGCCTCTACCTCAACTCGCCCGGCGGCTCGGTGACGGCGATGCTCGCGATCTAC
GACACCATGCAGTTCGTCCGGTCCCCGGTCGGTACGACGTGCGTCGGCCAGGCCGCCTCCTCCGCCGCGGTGCTGCTCGC
CGGCGGCGAGCCCGGCAGCCGGACCGTGCTGCCGCGGGCTCGAGTGGTGCTGCACCAGCCCTCCGGCGGTGGGCAGGGCA
CGCTGCCGGACCTCGCGCTGCAGGCCAAGGAGATCGTGCGGCTGCGGACCGCGATGGAGGAGATCCTGGCCGAGCACACC
GGCCGGTCGGTGGCCCAGGTGCACGCCGACACCGACCGGGACCTGGTTCTCTCCGCGGAGCAGGCGGTGGCGTACGGGCT
GGCCGACGCCGTCCTGGACAGCCGGAAGAAGGTCAACCGATGA

Upstream 100 bases:

>100_bases
AGCAGGCCCGCGAGTACGGCTTCGTCGACCGGGTCCTCACCGACGTGTCCGCGGTGACACCCGCGCGCCCGGCACCCTCG
TTCGGGCTGAGGTGAGCATG

Downstream 100 bases:

>100_bases
GCGGCGGGTCCGTCAGGCCGCCAGGCAGACCGGGCCGCTGACCCGGCTCAGCCGCCGGCTCACCCGCGAGGTGAGGTCGA
CCAGGCGCAGGCCGAGCGCA

Product: ATP-dependent Clp protease proteolytic subunit ClpP

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSTYTIPSVVERTARGERAVDIYSRLLTDRIVYVGTEIDDGVANVVIAQLLHLESDAPDQPISLYLNSPGGSVTAMLAIY
DTMQFVRSPVGTTCVGQAASSAAVLLAGGEPGSRTVLPRARVVLHQPSGGGQGTLPDLALQAKEIVRLRTAMEEILAEHT
GRSVAQVHADTDRDLVLSAEQAVAYGLADAVLDSRKKVNR

Sequences:

>Translated_200_residues
MSTYTIPSVVERTARGERAVDIYSRLLTDRIVYVGTEIDDGVANVVIAQLLHLESDAPDQPISLYLNSPGGSVTAMLAIY
DTMQFVRSPVGTTCVGQAASSAAVLLAGGEPGSRTVLPRARVVLHQPSGGGQGTLPDLALQAKEIVRLRTAMEEILAEHT
GRSVAQVHADTDRDLVLSAEQAVAYGLADAVLDSRKKVNR
>Mature_199_residues
STYTIPSVVERTARGERAVDIYSRLLTDRIVYVGTEIDDGVANVVIAQLLHLESDAPDQPISLYLNSPGGSVTAMLAIYD
TMQFVRSPVGTTCVGQAASSAAVLLAGGEPGSRTVLPRARVVLHQPSGGGQGTLPDLALQAKEIVRLRTAMEEILAEHTG
RSVAQVHADTDRDLVLSAEQAVAYGLADAVLDSRKKVNR

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=187, Percent_Identity=53.475935828877, Blast_Score=205, Evalue=3e-53,
Organism=Escherichia coli, GI1786641, Length=191, Percent_Identity=49.2146596858639, Blast_Score=214, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17538017, Length=186, Percent_Identity=50, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI20129427, Length=188, Percent_Identity=47.8723404255319, Blast_Score=194, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 21220; Mature: 21089

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00381 CLP_PROTEASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTYTIPSVVERTARGERAVDIYSRLLTDRIVYVGTEIDDGVANVVIAQLLHLESDAPDQ
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
PISLYLNSPGGSVTAMLAIYDTMQFVRSPVGTTCVGQAASSAAVLLAGGEPGSRTVLPRA
CEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEECCCCCCCEECCCE
RVVLHQPSGGGQGTLPDLALQAKEIVRLRTAMEEILAEHTGRSVAQVHADTDRDLVLSAE
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHH
QAVAYGLADAVLDSRKKVNR
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STYTIPSVVERTARGERAVDIYSRLLTDRIVYVGTEIDDGVANVVIAQLLHLESDAPDQ
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
PISLYLNSPGGSVTAMLAIYDTMQFVRSPVGTTCVGQAASSAAVLLAGGEPGSRTVLPRA
CEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEECCCCCCCEECCCE
RVVLHQPSGGGQGTLPDLALQAKEIVRLRTAMEEILAEHTGRSVAQVHADTDRDLVLSAE
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHH
QAVAYGLADAVLDSRKKVNR
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]