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The map label for this gene is clpP2 [H]

Identifier: 119716962

GI number: 119716962

Start: 2910241

End: 2910843

Strand: Reverse

Name: clpP2 [H]

Synonym: Noca_2737

Alternate gene names: 119716962

Gene position: 2910843-2910241 (Counterclockwise)

Preceding gene: 119716964

Following gene: 119716961

Centisome position: 58.38

GC content: 70.48

Gene sequence:

>603_bases
ATGACCCAGACACCCGCGCTCGCCGGCCTGTCCGCGGCCGACCGGCTGCTGCACCAGCGGATCATCGTGCTCGGCCAGCA
GGTCGACGACGACATCGCCAACAAGCTCTGCGCCGAGCTGCTCCTGCTCTCGGCGGAGGACCCCCACCGCGACATCGCGC
TCTACATCAACTCACCCGGCGGCTCGGTGAGCGCCGGGCTCGCCATCTACGACACCATGCGGCTGATCCCGAACGACGTC
AGCACCCTGGCGATGGGCCTCGCCGCCAGCATGGGCCAGTTCCTGCTCTCGGCCGGCACCCCCGGCAAGCGCTACGCGCT
GCCGCACTCGCGGGTGCTGATGCACCAGGGCTCCGCCGGGATCGGCGGCACCGCGATCGACATCGAGATCCAGGCCGAGA
ACCTCGAGCACACCAAGAACGTGATGACCGGCCTGATCGCCGAGCACACCGGCCAGCCCGTCGAGGTGATCGAGCGGGAC
TCGCTGCGGGACCGCTGGTTCACCGCCGAGCAGGCCCGCGAGTACGGCTTCGTCGACCGGGTCCTCACCGACGTGTCCGC
GGTGACACCCGCGCGCCCGGCACCCTCGTTCGGGCTGAGGTGA

Upstream 100 bases:

>100_bases
GGCGACCCTATCCAGCGGGGCCGTGGCTCCTCTGCCGAGGGCAGATCCGCCGACAGCGGATCCGCTGGGATCCCGACGGC
GTACGCCGCAGGCTCGAGCC

Downstream 100 bases:

>100_bases
GCATGGTGAGCACCTACACCATCCCCAGCGTGGTCGAGCGGACCGCGCGCGGCGAGCGGGCCGTGGACATCTACAGCCGG
CTGCTGACCGACCGGATCGT

Product: ClpP1 peptidase

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTQTPALAGLSAADRLLHQRIIVLGQQVDDDIANKLCAELLLLSAEDPHRDIALYINSPGGSVSAGLAIYDTMRLIPNDV
STLAMGLAASMGQFLLSAGTPGKRYALPHSRVLMHQGSAGIGGTAIDIEIQAENLEHTKNVMTGLIAEHTGQPVEVIERD
SLRDRWFTAEQAREYGFVDRVLTDVSAVTPARPAPSFGLR

Sequences:

>Translated_200_residues
MTQTPALAGLSAADRLLHQRIIVLGQQVDDDIANKLCAELLLLSAEDPHRDIALYINSPGGSVSAGLAIYDTMRLIPNDV
STLAMGLAASMGQFLLSAGTPGKRYALPHSRVLMHQGSAGIGGTAIDIEIQAENLEHTKNVMTGLIAEHTGQPVEVIERD
SLRDRWFTAEQAREYGFVDRVLTDVSAVTPARPAPSFGLR
>Mature_199_residues
TQTPALAGLSAADRLLHQRIIVLGQQVDDDIANKLCAELLLLSAEDPHRDIALYINSPGGSVSAGLAIYDTMRLIPNDVS
TLAMGLAASMGQFLLSAGTPGKRYALPHSRVLMHQGSAGIGGTAIDIEIQAENLEHTKNVMTGLIAEHTGQPVEVIERDS
LRDRWFTAEQAREYGFVDRVLTDVSAVTPARPAPSFGLR

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=170, Percent_Identity=47.6470588235294, Blast_Score=166, Evalue=2e-41,
Organism=Escherichia coli, GI1786641, Length=169, Percent_Identity=55.6213017751479, Blast_Score=193, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17538017, Length=169, Percent_Identity=47.9289940828402, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI20129427, Length=169, Percent_Identity=44.3786982248521, Blast_Score=149, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 21454; Mature: 21323

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTPALAGLSAADRLLHQRIIVLGQQVDDDIANKLCAELLLLSAEDPHRDIALYINSPG
CCCCCCHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GSVSAGLAIYDTMRLIPNDVSTLAMGLAASMGQFLLSAGTPGKRYALPHSRVLMHQGSAG
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHEEEECCCCC
IGGTAIDIEIQAENLEHTKNVMTGLIAEHTGQPVEVIERDSLRDRWFTAEQAREYGFVDR
CCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHCCHHHHHHHHHHHH
VLTDVSAVTPARPAPSFGLR
HHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TQTPALAGLSAADRLLHQRIIVLGQQVDDDIANKLCAELLLLSAEDPHRDIALYINSPG
CCCCCHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GSVSAGLAIYDTMRLIPNDVSTLAMGLAASMGQFLLSAGTPGKRYALPHSRVLMHQGSAG
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHEEEECCCCC
IGGTAIDIEIQAENLEHTKNVMTGLIAEHTGQPVEVIERDSLRDRWFTAEQAREYGFVDR
CCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHCCHHHHHHHHHHHH
VLTDVSAVTPARPAPSFGLR
HHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]