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The map label for this gene is cobQ [H]

Identifier: 119716735

GI number: 119716735

Start: 2676234

End: 2677721

Strand: Direct

Name: cobQ [H]

Synonym: Noca_2509

Alternate gene names: 119716735

Gene position: 2676234-2677721 (Clockwise)

Preceding gene: 119716734

Following gene: 119716736

Centisome position: 53.68

GC content: 74.6

Gene sequence:

>1488_bases
ATGAGCGGGATCCTGGTCGCGGGCACGAGCTCGGACGCCGGCAAGAGCGTCGTCACCACTGGACTGTGCCGCTCGCTGGC
GCGCGCGGGTGTGCACGTCGCGCCGTTCAAGGCGCAGAACATGTCGAACAACTCGATGGTCTGCGCGGACGGCGCGGAGA
TCGGCCGGGCGCAGTGGGTGCAGGCCGTGGCCGCGAACGCCGAGCCCGAGGCGGCGATGAACCCGGTGCTGCTCAAGCCG
GGCAGTGACCTGCGCAGCCACGTCGTCGTGATGGGTCGTCCCGGCGGCACGCTGGGCGCGGACGACTTCGCCGAGGGCCG
GGAGCCCCTGGCGGCTGCGGCGTACGCCGCCTTCGACGACCTGGCGTCGCGCTACGACGTCGTCGTCGCGGAGGGCGCCG
GCAGTCCAGCCGAGATCAACCTGCGGTCCGGCGACTTCGTGAACATGGGGCTCGCGCGGCACGCCGGCCTGCCGACGGTG
GTCGTCGGCGACATCGACCGGGGCGGCCTGCTGGCGGCCATGTTCGGCACCGTGGCGCTGCTCGAGCCCGCCGACCAGCG
GCTGCTCGCGGGGTTCGTCGTCAACAAGTTCCGCGGCGACCTCGACCTGCTGCGACCCGGGCTCGAGGAGGTCGCCCGGC
TCACCGGCCGGCCGGTGTACGGCGTGCTGCCGTGGCACCCCGACCTCTGGATGGACTCCGAGGACACCCTCGCCGTCGCC
GGCCGGCAGGCGCGCGACGGCCGGGCGGCGCTCAAGGTCGCGGTCGTGCGGCTGCCGCGGATCAGCAACGTGACCGACGT
CGACGCGCTCGGGATCGAGCCCAGCCTCGACGTCGTCTTCGCCACCGACCCGCGAGCCCTCTCGGACGCCGACCTGGTCG
TGCTGCCCGGGACCCGTGCGACCATCGCGGACCTCGCCTGGCTGCGCGAGCGGGGGCTGGACCGAGCCGTCCACGCGCAC
GCCGCTGCCGGTCGCCCGGTGCTCGGGATCTGCGGGGGCTTCCAGATGCTCGGCCGGTCCGTCTCGGATCCGGGCGGCGT
CGAGGGGCAGCCCGGCGCCGAGGTCGAGGGGCTGGCGCTGCTCGACGTACGCACCGACTTCTCCGCGGTGAAGGTGCTCC
GGCTCTCCCGGGGTCTCGCGCTCGGCGCCTCGACCGCTGGCTACGAGATCCACCACGGGAGGGTCACGCGGGGCGCCGGC
GCCGAGGAGTTCCTCGGCGGGGCCCGGGAGGGCCACGTGCTCGGCACGATGTGGCACGGCAGCCTCGAGGGCGACGCCTT
CCGCACGGCGTTCCTGACCGAGGTCGCGCGGCTGACCGGTCACGTGTGGGAGCCTTCCGGGGTGAGCTTCGCGGCGGCAC
GGGAGGGGCGGATGGAGCTGCTCGCCGACCTCGTCGAGGAGCACCTCGACGTCGCCGCGATCGCCGCCCTCGCCTCCGAG
GGCGTACCCGACGGCCTGCCGGTCCTGCCGCCGGGCGCTGACCGGTGA

Upstream 100 bases:

>100_bases
GGCGGCTACATGGCCCGCTGACGCGGGCCGTCCGTCCGACACCCGCGGCCAGGGACCCGCCGGCAGCCGATGCTGCCGGG
CTTCCTATGCTGGGCTGCCC

Downstream 100 bases:

>100_bases
AGGTCCTGGTCACCGGTGGGGTCCGGTCCGGCAAGTCCACGCACGCCGAGGCCCTGGTGCGTGCCGAGCCCGCCGTCACC
TACGTCGCCCCGGGTCCGGC

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSGILVAGTSSDAGKSVVTTGLCRSLARAGVHVAPFKAQNMSNNSMVCADGAEIGRAQWVQAVAANAEPEAAMNPVLLKP
GSDLRSHVVVMGRPGGTLGADDFAEGREPLAAAAYAAFDDLASRYDVVVAEGAGSPAEINLRSGDFVNMGLARHAGLPTV
VVGDIDRGGLLAAMFGTVALLEPADQRLLAGFVVNKFRGDLDLLRPGLEEVARLTGRPVYGVLPWHPDLWMDSEDTLAVA
GRQARDGRAALKVAVVRLPRISNVTDVDALGIEPSLDVVFATDPRALSDADLVVLPGTRATIADLAWLRERGLDRAVHAH
AAAGRPVLGICGGFQMLGRSVSDPGGVEGQPGAEVEGLALLDVRTDFSAVKVLRLSRGLALGASTAGYEIHHGRVTRGAG
AEEFLGGAREGHVLGTMWHGSLEGDAFRTAFLTEVARLTGHVWEPSGVSFAAAREGRMELLADLVEEHLDVAAIAALASE
GVPDGLPVLPPGADR

Sequences:

>Translated_495_residues
MSGILVAGTSSDAGKSVVTTGLCRSLARAGVHVAPFKAQNMSNNSMVCADGAEIGRAQWVQAVAANAEPEAAMNPVLLKP
GSDLRSHVVVMGRPGGTLGADDFAEGREPLAAAAYAAFDDLASRYDVVVAEGAGSPAEINLRSGDFVNMGLARHAGLPTV
VVGDIDRGGLLAAMFGTVALLEPADQRLLAGFVVNKFRGDLDLLRPGLEEVARLTGRPVYGVLPWHPDLWMDSEDTLAVA
GRQARDGRAALKVAVVRLPRISNVTDVDALGIEPSLDVVFATDPRALSDADLVVLPGTRATIADLAWLRERGLDRAVHAH
AAAGRPVLGICGGFQMLGRSVSDPGGVEGQPGAEVEGLALLDVRTDFSAVKVLRLSRGLALGASTAGYEIHHGRVTRGAG
AEEFLGGAREGHVLGTMWHGSLEGDAFRTAFLTEVARLTGHVWEPSGVSFAAAREGRMELLADLVEEHLDVAAIAALASE
GVPDGLPVLPPGADR
>Mature_494_residues
SGILVAGTSSDAGKSVVTTGLCRSLARAGVHVAPFKAQNMSNNSMVCADGAEIGRAQWVQAVAANAEPEAAMNPVLLKPG
SDLRSHVVVMGRPGGTLGADDFAEGREPLAAAAYAAFDDLASRYDVVVAEGAGSPAEINLRSGDFVNMGLARHAGLPTVV
VGDIDRGGLLAAMFGTVALLEPADQRLLAGFVVNKFRGDLDLLRPGLEEVARLTGRPVYGVLPWHPDLWMDSEDTLAVAG
RQARDGRAALKVAVVRLPRISNVTDVDALGIEPSLDVVFATDPRALSDADLVVLPGTRATIADLAWLRERGLDRAVHAHA
AAGRPVLGICGGFQMLGRSVSDPGGVEGQPGAEVEGLALLDVRTDFSAVKVLRLSRGLALGASTAGYEIHHGRVTRGAGA
EEFLGGAREGHVLGTMWHGSLEGDAFRTAFLTEVARLTGHVWEPSGVSFAAAREGRMELLADLVEEHLDVAAIAALASEG
VPDGLPVLPPGADR

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: 6.3.5.10

Molecular weight: Translated: 51420; Mature: 51289

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGILVAGTSSDAGKSVVTTGLCRSLARAGVHVAPFKAQNMSNNSMVCADGAEIGRAQWV
CCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCHHHHHHHHH
QAVAANAEPEAAMNPVLLKPGSDLRSHVVVMGRPGGTLGADDFAEGREPLAAAAYAAFDD
HHHHCCCCCCHHCCCEEECCCCCCCCCEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHH
LASRYDVVVAEGAGSPAEINLRSGDFVNMGLARHAGLPTVVVGDIDRGGLLAAMFGTVAL
HHCCCEEEEECCCCCCCEEEECCCCEEECCHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
LEPADQRLLAGFVVNKFRGDLDLLRPGLEEVARLTGRPVYGVLPWHPDLWMDSEDTLAVA
CCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEC
GRQARDGRAALKVAVVRLPRISNVTDVDALGIEPSLDVVFATDPRALSDADLVVLPGTRA
CCCCCCCHHHHEEEEEECCCCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCEEEECCCCH
TIADLAWLRERGLDRAVHAHAAAGRPVLGICGGFQMLGRSVSDPGGVEGQPGAEVEGLAL
HHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCEEE
LDVRTDFSAVKVLRLSRGLALGASTAGYEIHHGRVTRGAGAEEFLGGAREGHVLGTMWHG
EEECCCHHHHHHHHHHCCCEECCCCCCEEEECCEEECCCCHHHHHCCCCCCCEEEEEECC
SLEGDAFRTAFLTEVARLTGHVWEPSGVSFAAAREGRMELLADLVEEHLDVAAIAALASE
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
GVPDGLPVLPPGADR
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
SGILVAGTSSDAGKSVVTTGLCRSLARAGVHVAPFKAQNMSNNSMVCADGAEIGRAQWV
CCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCHHHHHHHHH
QAVAANAEPEAAMNPVLLKPGSDLRSHVVVMGRPGGTLGADDFAEGREPLAAAAYAAFDD
HHHHCCCCCCHHCCCEEECCCCCCCCCEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHH
LASRYDVVVAEGAGSPAEINLRSGDFVNMGLARHAGLPTVVVGDIDRGGLLAAMFGTVAL
HHCCCEEEEECCCCCCCEEEECCCCEEECCHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
LEPADQRLLAGFVVNKFRGDLDLLRPGLEEVARLTGRPVYGVLPWHPDLWMDSEDTLAVA
CCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEC
GRQARDGRAALKVAVVRLPRISNVTDVDALGIEPSLDVVFATDPRALSDADLVVLPGTRA
CCCCCCCHHHHEEEEEECCCCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCEEEECCCCH
TIADLAWLRERGLDRAVHAHAAAGRPVLGICGGFQMLGRSVSDPGGVEGQPGAEVEGLAL
HHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCEEE
LDVRTDFSAVKVLRLSRGLALGASTAGYEIHHGRVTRGAGAEEFLGGAREGHVLGTMWHG
EEECCCHHHHHHHHHHCCCEECCCCCCEEEECCEEECCCCHHHHHCCCCCCCEEEEEECC
SLEGDAFRTAFLTEVARLTGHVWEPSGVSFAAAREGRMELLADLVEEHLDVAAIAALASE
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
GVPDGLPVLPPGADR
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA