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The map label for this gene is cobU [H]

Identifier: 119716736

GI number: 119716736

Start: 2677718

End: 2678239

Strand: Direct

Name: cobU [H]

Synonym: Noca_2510

Alternate gene names: 119716736

Gene position: 2677718-2678239 (Clockwise)

Preceding gene: 119716735

Following gene: 119716740

Centisome position: 53.71

GC content: 75.86

Gene sequence:

>522_bases
GTGAAGGTCCTGGTCACCGGTGGGGTCCGGTCCGGCAAGTCCACGCACGCCGAGGCCCTGGTGCGTGCCGAGCCCGCCGT
CACCTACGTCGCCCCGGGTCCGGCCCAGGACGACGCCGACTGGGCCGCTCGGGTCGCCGCCCACCGCGCCCGCCGGCCGG
CCACCTGGACCACACTCGAGACCGGCGACCTCGCCGCAGCGCTGCGCACCCCCGGCCCGGTGCTGGTGGACTGCCTCGGC
ACCTGGCTGACCCGGCAAGTCGACGAGGCCGGGCTCTGGGAGGCCGAGTCCGACGCAGTGGCGGCGTACGTCGACGCCCG
GGTGAGCGAGGCGCTGACGGTGCTGGCCGGGCGTCCGGACGGGCCCGTGGTGCTGGTCACCAACGAGGTCGGTCTCGGCG
TGGTCCCCGAGCACCGCTCCGGCCGCCTGTTCCGGGACCTCCTCGGGGTCGTCAACCAGCGGTTCGGCCCGGCCTGCGAC
GAGGTGCACCTCGTCGTCGCGGGCCGGGTCCTCGTCCTCTAG

Upstream 100 bases:

>100_bases
CCGACCTCGTCGAGGAGCACCTCGACGTCGCCGCGATCGCCGCCCTCGCCTCCGAGGGCGTACCCGACGGCCTGCCGGTC
CTGCCGCCGGGCGCTGACCG

Downstream 100 bases:

>100_bases
CGTCGCGTCTTGGAAGTTGTTGAACGGTTGGCGTTCTCAGGGTGTGTGCATCGCAACGCGCCGGCGCGCCGCCATACCCA
CTCGTCTCGCAAGCGTCGGC

Product: adenosylcobinamide kinase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKVLVTGGVRSGKSTHAEALVRAEPAVTYVAPGPAQDDADWAARVAAHRARRPATWTTLETGDLAAALRTPGPVLVDCLG
TWLTRQVDEAGLWEAESDAVAAYVDARVSEALTVLAGRPDGPVVLVTNEVGLGVVPEHRSGRLFRDLLGVVNQRFGPACD
EVHLVVAGRVLVL

Sequences:

>Translated_173_residues
MKVLVTGGVRSGKSTHAEALVRAEPAVTYVAPGPAQDDADWAARVAAHRARRPATWTTLETGDLAAALRTPGPVLVDCLG
TWLTRQVDEAGLWEAESDAVAAYVDARVSEALTVLAGRPDGPVVLVTNEVGLGVVPEHRSGRLFRDLLGVVNQRFGPACD
EVHLVVAGRVLVL
>Mature_173_residues
MKVLVTGGVRSGKSTHAEALVRAEPAVTYVAPGPAQDDADWAARVAAHRARRPATWTTLETGDLAAALRTPGPVLVDCLG
TWLTRQVDEAGLWEAESDAVAAYVDARVSEALTVLAGRPDGPVVLVTNEVGLGVVPEHRSGRLFRDLLGVVNQRFGPACD
EVHLVVAGRVLVL

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=179, Percent_Identity=41.340782122905, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18246; Mature: 18246

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGGVRSGKSTHAEALVRAEPAVTYVAPGPAQDDADWAARVAAHRARRPATWTTLE
CEEEEECCCCCCCCHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEE
TGDLAAALRTPGPVLVDCLGTWLTRQVDEAGLWEAESDAVAAYVDARVSEALTVLAGRPD
CCCCEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHEEECCCC
GPVVLVTNEVGLGVVPEHRSGRLFRDLLGVVNQRFGPACDEVHLVVAGRVLVL
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECEEEEC
>Mature Secondary Structure
MKVLVTGGVRSGKSTHAEALVRAEPAVTYVAPGPAQDDADWAARVAAHRARRPATWTTLE
CEEEEECCCCCCCCHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEE
TGDLAAALRTPGPVLVDCLGTWLTRQVDEAGLWEAESDAVAAYVDARVSEALTVLAGRPD
CCCCEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHEEECCCC
GPVVLVTNEVGLGVVPEHRSGRLFRDLLGVVNQRFGPACDEVHLVVAGRVLVL
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9601028; 10529169 [H]