Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 119716728

GI number: 119716728

Start: 2669643

End: 2670407

Strand: Direct

Name: plsC [H]

Synonym: Noca_2502

Alternate gene names: 119716728

Gene position: 2669643-2670407 (Clockwise)

Preceding gene: 119716727

Following gene: 119716729

Centisome position: 53.54

GC content: 72.81

Gene sequence:

>765_bases
ATGAAGGACGTCTCCGCCCACCGTGAGCTGCCGCGCAGCGACACCGCCCGGGGCGCGCCCCGCTACGCCCTGTACTCGCC
GCTGCGCCCGCTGGCGCGCTGGTTGATCCGGCGGTGGTACGACGTGCGCGTGCACGAGCCCCGGCACGTGCCGCGCCACG
GGGGAGTGATCTACGCCTCCAACCACGTCGGGATCGTCGACGGGCCGCTGCTGGCCATCTTCGCGCCCCGCCCGGCGCAC
GCGCTGACCAAGATCGAGATGTTCCGTGGCCTGCTCGGGCGCTTCCTCGTGCAGTCCGGCCAGATCCCGCTGGACCGGTT
CCACACCGATCCCGCCGCGGTGAAGACGTGCCTGAAGGTGCTGCGCGACGGGGGCGCGGTCGGCATCTACCCCGAGGGCA
GCCGCGGCGCGGGCGACCTCGAGCGGTTCCACCGGGGTGCGGCCTACCTCGCGCTGGTGTCCGGCGCACCGGTCGTACCG
GTCACGATGCTCGGGAGCCGCGAGCCCGGCGCCCACCACAACTCGCTGCCAGCCCGGCGGGCCCGGATCGACCTGGTTTT
CGGGGAGGCCTACCGCATCGACCCGGTGCCGTGGCCGCGGACCCGGGAACAAGTCGAGAAGTTCTCGTTGTTGCTGCGGG
AGCACATGCTGGTCCAGCTGGACCGCGCGCGCACGTCGACCGGCCGGGAGCTGCCGGGTCCGCTGCCCGTGACCGACGTA
GACCCAGACCCCGCCACCGGGGTCACCGACCAAGGAGCACCATGA

Upstream 100 bases:

>100_bases
CGACACCACGCCGTACTCCCTCGACGAGGTCATCGACCTGGTCGTCGAGCTCGCCGAGCAGGCCGCGGCGCGGGCGTGAG
GACGACCCGATGAGGCCTCG

Downstream 100 bases:

>100_bases
CCGAGCTCGAGGGTGCCCCCGAGGGCGCCCCGGAGACCGCTGCGGAGACCGTCCCCGAGGCCGCCGGACCCGTCCCCGTC
CTCGCGGTCGTCGGCCGACC

Product: phospholipid/glycerol acyltransferase

Products: [acyl carrier protein]; L-1-phosphatidyl-ethanolamine; AMP; pyrophosphate; acyl-ACP [C]

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; 1-acyl-G3P acyltransferase; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKDVSAHRELPRSDTARGAPRYALYSPLRPLARWLIRRWYDVRVHEPRHVPRHGGVIYASNHVGIVDGPLLAIFAPRPAH
ALTKIEMFRGLLGRFLVQSGQIPLDRFHTDPAAVKTCLKVLRDGGAVGIYPEGSRGAGDLERFHRGAAYLALVSGAPVVP
VTMLGSREPGAHHNSLPARRARIDLVFGEAYRIDPVPWPRTREQVEKFSLLLREHMLVQLDRARTSTGRELPGPLPVTDV
DPDPATGVTDQGAP

Sequences:

>Translated_254_residues
MKDVSAHRELPRSDTARGAPRYALYSPLRPLARWLIRRWYDVRVHEPRHVPRHGGVIYASNHVGIVDGPLLAIFAPRPAH
ALTKIEMFRGLLGRFLVQSGQIPLDRFHTDPAAVKTCLKVLRDGGAVGIYPEGSRGAGDLERFHRGAAYLALVSGAPVVP
VTMLGSREPGAHHNSLPARRARIDLVFGEAYRIDPVPWPRTREQVEKFSLLLREHMLVQLDRARTSTGRELPGPLPVTDV
DPDPATGVTDQGAP
>Mature_254_residues
MKDVSAHRELPRSDTARGAPRYALYSPLRPLARWLIRRWYDVRVHEPRHVPRHGGVIYASNHVGIVDGPLLAIFAPRPAH
ALTKIEMFRGLLGRFLVQSGQIPLDRFHTDPAAVKTCLKVLRDGGAVGIYPEGSRGAGDLERFHRGAAYLALVSGAPVVP
VTMLGSREPGAHHNSLPARRARIDLVFGEAYRIDPVPWPRTREQVEKFSLLLREHMLVQLDRARTSTGRELPGPLPVTDV
DPDPATGVTDQGAP

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cytoplasm. Note=Probably associated with the membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789201, Length=148, Percent_Identity=35.1351351351351, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: NA

Molecular weight: Translated: 28070; Mature: 28070

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDVSAHRELPRSDTARGAPRYALYSPLRPLARWLIRRWYDVRVHEPRHVPRHGGVIYAS
CCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCEEEEC
NHVGIVDGPLLAIFAPRPAHALTKIEMFRGLLGRFLVQSGQIPLDRFHTDPAAVKTCLKV
CCCCEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHH
LRDGGAVGIYPEGSRGAGDLERFHRGAAYLALVSGAPVVPVTMLGSREPGAHHNSLPARR
HHCCCEEEECCCCCCCCHHHHHHHCCHHEEEEECCCCEEEEEEECCCCCCCCCCCCCCHH
ARIDLVFGEAYRIDPVPWPRTREQVEKFSLLLREHMLVQLDRARTSTGRELPGPLPVTDV
HEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DPDPATGVTDQGAP
CCCCCCCCCCCCCC
>Mature Secondary Structure
MKDVSAHRELPRSDTARGAPRYALYSPLRPLARWLIRRWYDVRVHEPRHVPRHGGVIYAS
CCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCEEEEC
NHVGIVDGPLLAIFAPRPAHALTKIEMFRGLLGRFLVQSGQIPLDRFHTDPAAVKTCLKV
CCCCEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHH
LRDGGAVGIYPEGSRGAGDLERFHRGAAYLALVSGAPVVPVTMLGSREPGAHHNSLPARR
HHCCCEEEECCCCCCCCHHHHHHHCCHHEEEEECCCCEEEEEEECCCCCCCCCCCCCCHH
ARIDLVFGEAYRIDPVPWPRTREQVEKFSLLLREHMLVQLDRARTSTGRELPGPLPVTDV
HEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DPDPATGVTDQGAP
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-ACP; 2-acyl-sn-glycero-3-phosphoethanolamine; ATP; a fatty acid [C]

Specific reaction: acyl-ACP + 2-acyl-sn-glycero-3-phosphoethanolamine = [acyl carrier protein] + L-1-phosphatidyl-ethanolamine ATP + a fatty acid + [acyl carrier protein] = AMP + pyrophosphate + acyl-ACP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]