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The map label for this gene is engA [H]

Identifier: 119716729

GI number: 119716729

Start: 2670404

End: 2671789

Strand: Direct

Name: engA [H]

Synonym: Noca_2503

Alternate gene names: 119716729

Gene position: 2670404-2671789 (Clockwise)

Preceding gene: 119716728

Following gene: 119716731

Centisome position: 53.56

GC content: 72.44

Gene sequence:

>1386_bases
ATGACCGAGCTCGAGGGTGCCCCCGAGGGCGCCCCGGAGACCGCTGCGGAGACCGTCCCCGAGGCCGCCGGACCCGTCCC
CGTCCTCGCGGTCGTCGGCCGACCCAACGTCGGGAAGTCGACGCTGGTGAACCGGATCATCGGCCGCCGCGAGGCAGTCG
TCGAGGACGTCCCCGGTGTGACCCGCGACCGCGTCTCCTACGACGCGAGCTGGAACGGCCGCGCGTTCACCGTCGTCGAC
ACCGGCGGCTGGGATCCGGACGCCCGCGGCCTGGCCGAGCGGATCGCCGGGCAGGCGGAGGTCGCGGTCAGCCTGGCCGA
CGCCGTGCTGTTCGTGGTCGATGCGACCGTTGGGATCACCGACGCCGACGAGGCCGTCGTGCGGATCCTGCGGAAGTCCG
CGAAGCCGGTCGTGCTGGCCGCGAACAAGGTCGACGACCAGCGCACCGAGGCGGAGGCCTACGGGCTGTGGAACCTCGGG
CTCGGCGAGCCGTACGCCGTGTCCGCGCTGCACGGTCGTGGCTCGGGCGACCTGCTCGACGCCGTGCTGGCGGCGCTTCC
CGAGCCGCCTCCCGAGCGTGAGCCGGAGCCCGGCGGGCCGCGGCGGATCGCGATCGTCGGCAAGCCCAACGTCGGCAAGT
CCTCCCTGCTCAACAAGCTCGCCGGCGAGGAGCGGGCCGTGGTCGACAACGTCGCCGGCACCACCGTCGACCCGGTCGAC
GAGCTGATCGAGCTCGGCGGCAAGACCTGGCGGTTCATCGACACCGCGGGCATCCGCAAGCGGGTCAAGGAGGCCTCCGG
GCACGAGTACTACGCCTCGCTGCGCACCGCGACGGCGATCGACCGGGCCGAGGTCGCGGTCCTGGTCGTCGACGGCGGGG
AGTCGATCTCCGAGCAGGACGTCCGGATCATCCAGACCGTCCGCGAGGCCGGCCGCGCGCTCGTCATCGCCTTCAACAAG
TGGGACCTCGTCGACGAGGAGCGCCGCTACTACCTCGACCGTGAGATCGAGCGCGACCTCGTCCAGGTGCAGTGGGCCCC
GCGGATCAACATCACCGCCCGGACCGGGTGGCACGTCGACCGGCTCGTCCCGGCGCTGGAGAAGGCCCTGGAGGGCTGGG
AGACCCGCGTCTCGACCGGCGCGCTCAACGGCTTCCTCGGCCGCCTGGTCGCCGAGCACCCCCACCCGGTGCGCAGCGGC
AAGCAGCCGAAGATCCTGTTCGGGACCCAGGCCTCGACCGCGCCGCCGACCTTCATCCTGTTCACGAGCGGCAAGCTGGA
CGCCGCCTACGAGCGGTTCATCGAGCGTCGCCTGCGCGAGGAGTTCGGGTTCGTGGGCACGCCGATCGTGCTGCAGCAGC
GGCCGCGGGAGAAGCGCAAGCGGTAG

Upstream 100 bases:

>100_bases
ACCGCGCGCGCACGTCGACCGGCCGGGAGCTGCCGGGTCCGCTGCCCGTGACCGACGTAGACCCAGACCCCGCCACCGGG
GTCACCGACCAAGGAGCACC

Downstream 100 bases:

>100_bases
CCCGCGGGTCAGCGTCGGGCCATGCGCAGGCTCGTGGTCCTCGCCCAGGCCGGGGGCGTCGCGGGTCGTGTGCCCCACGA
CGCGCCATAGCGCGTGCTGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MTELEGAPEGAPETAAETVPEAAGPVPVLAVVGRPNVGKSTLVNRIIGRREAVVEDVPGVTRDRVSYDASWNGRAFTVVD
TGGWDPDARGLAERIAGQAEVAVSLADAVLFVVDATVGITDADEAVVRILRKSAKPVVLAANKVDDQRTEAEAYGLWNLG
LGEPYAVSALHGRGSGDLLDAVLAALPEPPPEREPEPGGPRRIAIVGKPNVGKSSLLNKLAGEERAVVDNVAGTTVDPVD
ELIELGGKTWRFIDTAGIRKRVKEASGHEYYASLRTATAIDRAEVAVLVVDGGESISEQDVRIIQTVREAGRALVIAFNK
WDLVDEERRYYLDREIERDLVQVQWAPRINITARTGWHVDRLVPALEKALEGWETRVSTGALNGFLGRLVAEHPHPVRSG
KQPKILFGTQASTAPPTFILFTSGKLDAAYERFIERRLREEFGFVGTPIVLQQRPREKRKR

Sequences:

>Translated_461_residues
MTELEGAPEGAPETAAETVPEAAGPVPVLAVVGRPNVGKSTLVNRIIGRREAVVEDVPGVTRDRVSYDASWNGRAFTVVD
TGGWDPDARGLAERIAGQAEVAVSLADAVLFVVDATVGITDADEAVVRILRKSAKPVVLAANKVDDQRTEAEAYGLWNLG
LGEPYAVSALHGRGSGDLLDAVLAALPEPPPEREPEPGGPRRIAIVGKPNVGKSSLLNKLAGEERAVVDNVAGTTVDPVD
ELIELGGKTWRFIDTAGIRKRVKEASGHEYYASLRTATAIDRAEVAVLVVDGGESISEQDVRIIQTVREAGRALVIAFNK
WDLVDEERRYYLDREIERDLVQVQWAPRINITARTGWHVDRLVPALEKALEGWETRVSTGALNGFLGRLVAEHPHPVRSG
KQPKILFGTQASTAPPTFILFTSGKLDAAYERFIERRLREEFGFVGTPIVLQQRPREKRKR
>Mature_460_residues
TELEGAPEGAPETAAETVPEAAGPVPVLAVVGRPNVGKSTLVNRIIGRREAVVEDVPGVTRDRVSYDASWNGRAFTVVDT
GGWDPDARGLAERIAGQAEVAVSLADAVLFVVDATVGITDADEAVVRILRKSAKPVVLAANKVDDQRTEAEAYGLWNLGL
GEPYAVSALHGRGSGDLLDAVLAALPEPPPEREPEPGGPRRIAIVGKPNVGKSSLLNKLAGEERAVVDNVAGTTVDPVDE
LIELGGKTWRFIDTAGIRKRVKEASGHEYYASLRTATAIDRAEVAVLVVDGGESISEQDVRIIQTVREAGRALVIAFNKW
DLVDEERRYYLDREIERDLVQVQWAPRINITARTGWHVDRLVPALEKALEGWETRVSTGALNGFLGRLVAEHPHPVRSGK
QPKILFGTQASTAPPTFILFTSGKLDAAYERFIERRLREEFGFVGTPIVLQQRPREKRKR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=36.2637362637363, Blast_Score=271, Evalue=9e-74,
Organism=Escherichia coli, GI2367268, Length=190, Percent_Identity=32.1052631578947, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788919, Length=126, Percent_Identity=35.7142857142857, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=128, Percent_Identity=36.71875, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=180, Percent_Identity=26.1111111111111, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50089; Mature: 49958

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELEGAPEGAPETAAETVPEAAGPVPVLAVVGRPNVGKSTLVNRIIGRREAVVEDVPGV
CCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
TRDRVSYDASWNGRAFTVVDTGGWDPDARGLAERIAGQAEVAVSLADAVLFVVDATVGIT
CHHCEEECCCCCCEEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
DADEAVVRILRKSAKPVVLAANKVDDQRTEAEAYGLWNLGLGEPYAVSALHGRGSGDLLD
CHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCEEEECCCCCCEEEEEECCCCCHHHHH
AVLAALPEPPPEREPEPGGPRRIAIVGKPNVGKSSLLNKLAGEERAVVDNVAGTTVDPVD
HHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHCCCCCCCHHH
ELIELGGKTWRFIDTAGIRKRVKEASGHEYYASLRTATAIDRAEVAVLVVDGGESISEQD
HHHHCCCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHH
VRIIQTVREAGRALVIAFNKWDLVDEERRYYLDREIERDLVQVQWAPRINITARTGWHVD
HHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCHH
RLVPALEKALEGWETRVSTGALNGFLGRLVAEHPHPVRSGKQPKILFGTQASTAPPTFIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEE
FTSGKLDAAYERFIERRLREEFGFVGTPIVLQQRPREKRKR
EECCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHCC
>Mature Secondary Structure 
TELEGAPEGAPETAAETVPEAAGPVPVLAVVGRPNVGKSTLVNRIIGRREAVVEDVPGV
CCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
TRDRVSYDASWNGRAFTVVDTGGWDPDARGLAERIAGQAEVAVSLADAVLFVVDATVGIT
CHHCEEECCCCCCEEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
DADEAVVRILRKSAKPVVLAANKVDDQRTEAEAYGLWNLGLGEPYAVSALHGRGSGDLLD
CHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCEEEECCCCCCEEEEEECCCCCHHHHH
AVLAALPEPPPEREPEPGGPRRIAIVGKPNVGKSSLLNKLAGEERAVVDNVAGTTVDPVD
HHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHCCCCCCCHHH
ELIELGGKTWRFIDTAGIRKRVKEASGHEYYASLRTATAIDRAEVAVLVVDGGESISEQD
HHHHCCCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHH
VRIIQTVREAGRALVIAFNKWDLVDEERRYYLDREIERDLVQVQWAPRINITARTGWHVD
HHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCHH
RLVPALEKALEGWETRVSTGALNGFLGRLVAEHPHPVRSGKQPKILFGTQASTAPPTFIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEE
FTSGKLDAAYERFIERRLREEFGFVGTPIVLQQRPREKRKR
EECCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA