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The map label for this gene is ribH

Identifier: 119716676

GI number: 119716676

Start: 2612460

End: 2612945

Strand: Direct

Name: ribH

Synonym: Noca_2450

Alternate gene names: 119716676

Gene position: 2612460-2612945 (Clockwise)

Preceding gene: 119716675

Following gene: 119716677

Centisome position: 52.4

GC content: 73.66

Gene sequence:

>486_bases
ATGTCCGGACACGGAGCACCTGCCCCGGCGCCCGTCGACTGCAGTGACCTGCGGGTCGCCGTCGTCGCCGCCAGCTGGCA
CACGCAGGTGATGGACGGCCTGATCGCGGGCGCGCAGCGCGCGCTGGCGGACTACCACGTCGCGGAGCACCGGCTGGTCC
GCGTGCCGGGCGCCTTCGAGCTCGCGGTGGTCGCCGACGCCCTCGCCCGCCAGCACTACGACGTGGTCGTGGCGTTGGGC
GTGGTCATCCGCGGCGGCACGCCGCACTTCGACTACGTCTGCCAGGCGGTGACCGAGGGTCTGGTCCGGGTCGCGCTCGA
CCGTAGTCTCCCGGTCGGCTTCGGCGTCCTCACCTGCGACGGCGACCAGCAGGCGCTCGACCGCGCCGGCCTGGAGGGCT
CGAAGGAGGACAAGGGCTACGAGGCCACGTCCGCTGCGCTGCTCACCGCCCGGACCCTGAAGGAGCTCGGGACCACCGCC
CCGTAG

Upstream 100 bases:

>100_bases
CGACCGAATGGGTCACGATCTGCCCAACCTTGCCGATGGGGTGCCCGACACCCGTGCCGACGGGGTGCCCGACACCCTTG
CCCAGAACGGAGCCTGACCG

Downstream 100 bases:

>100_bases
GCTGGTGGCCTGTGAAGACGTTCGACGAGCTCTGGGCCGAGCTGAGCGAGAAGGCCCGGTCCCGCCCCGAGGGGTCCGGA
ACCGTGCGCGCGCTCGACGC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSGHGAPAPAPVDCSDLRVAVVAASWHTQVMDGLIAGAQRALADYHVAEHRLVRVPGAFELAVVADALARQHYDVVVALG
VVIRGGTPHFDYVCQAVTEGLVRVALDRSLPVGFGVLTCDGDQQALDRAGLEGSKEDKGYEATSAALLTARTLKELGTTA
P

Sequences:

>Translated_161_residues
MSGHGAPAPAPVDCSDLRVAVVAASWHTQVMDGLIAGAQRALADYHVAEHRLVRVPGAFELAVVADALARQHYDVVVALG
VVIRGGTPHFDYVCQAVTEGLVRVALDRSLPVGFGVLTCDGDQQALDRAGLEGSKEDKGYEATSAALLTARTLKELGTTA
P
>Mature_160_residues
SGHGAPAPAPVDCSDLRVAVVAASWHTQVMDGLIAGAQRALADYHVAEHRLVRVPGAFELAVVADALARQHYDVVVALGV
VIRGGTPHFDYVCQAVTEGLVRVALDRSLPVGFGVLTCDGDQQALDRAGLEGSKEDKGYEATSAALLTARTLKELGTTAP

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=151, Percent_Identity=43.7086092715232, Blast_Score=104, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324429, Length=128, Percent_Identity=35.9375, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_NOCSJ (A1SJG9)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_923641.1
- ProteinModelPortal:   A1SJG9
- SMR:   A1SJG9
- STRING:   A1SJG9
- GeneID:   4599791
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_2450
- eggNOG:   COG0054
- HOGENOM:   HBG311126
- OMA:   LGLQGAC
- PhylomeDB:   A1SJG9
- BioCyc:   NSP35761:NOCA_2450-MONOMER
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16798; Mature: 16667

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGHGAPAPAPVDCSDLRVAVVAASWHTQVMDGLIAGAQRALADYHVAEHRLVRVPGAFE
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHH
LAVVADALARQHYDVVVALGVVIRGGTPHFDYVCQAVTEGLVRVALDRSLPVGFGVLTCD
HHHHHHHHHHHHHHHHHHEEHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
GDQQALDRAGLEGSKEDKGYEATSAALLTARTLKELGTTAP
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGHGAPAPAPVDCSDLRVAVVAASWHTQVMDGLIAGAQRALADYHVAEHRLVRVPGAFE
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHH
LAVVADALARQHYDVVVALGVVIRGGTPHFDYVCQAVTEGLVRVALDRSLPVGFGVLTCD
HHHHHHHHHHHHHHHHHHEEHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
GDQQALDRAGLEGSKEDKGYEATSAALLTARTLKELGTTAP
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA