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The map label for this gene is hisE

Identifier: 119716677

GI number: 119716677

Start: 2612957

End: 2613220

Strand: Direct

Name: hisE

Synonym: Noca_2451

Alternate gene names: 119716677

Gene position: 2612957-2613220 (Clockwise)

Preceding gene: 119716676

Following gene: 119716678

Centisome position: 52.41

GC content: 69.32

Gene sequence:

>264_bases
GTGAAGACGTTCGACGAGCTCTGGGCCGAGCTGAGCGAGAAGGCCCGGTCCCGCCCCGAGGGGTCCGGAACCGTGCGCGC
GCTCGACGCGGGCGTCCACGGCATCGGCAAGAAGCTGGTCGAGGAGGCCGCAGAGTCCTGGATGGCCGCCGAGCACGAGG
GACCCGAACGCGCGGCCGAGGAGATCAGCCAGTTGCTCTACCACGCCCAGGTGCTGATGCTCGCCACCGGCATCGACCTC
GACGACGTCTACGCACACCTGTGA

Upstream 100 bases:

>100_bases
GCTCGAAGGAGGACAAGGGCTACGAGGCCACGTCCGCTGCGCTGCTCACCGCCCGGACCCTGAAGGAGCTCGGGACCACC
GCCCCGTAGGCTGGTGGCCT

Downstream 100 bases:

>100_bases
GGAGGCGCTCGATGGCTCTGCTGCGCATCGCGGTCCCGAACAAGGGATCGCTGTCCCAGTCCGCCTCGGAGATCCTGCGC
GAGTCCGGCTACCGCCAGCG

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH

Number of amino acids: Translated: 87; Mature: 87

Protein sequence:

>87_residues
MKTFDELWAELSEKARSRPEGSGTVRALDAGVHGIGKKLVEEAAESWMAAEHEGPERAAEEISQLLYHAQVLMLATGIDL
DDVYAHL

Sequences:

>Translated_87_residues
MKTFDELWAELSEKARSRPEGSGTVRALDAGVHGIGKKLVEEAAESWMAAEHEGPERAAEEISQLLYHAQVLMLATGIDL
DDVYAHL
>Mature_87_residues
MKTFDELWAELSEKARSRPEGSGTVRALDAGVHGIGKKLVEEAAESWMAAEHEGPERAAEEISQLLYHAQVLMLATGIDL
DDVYAHL

Specific function: Unknown

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HIS2_NOCSJ (A1SJH0)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_923642.1
- ProteinModelPortal:   A1SJH0
- SMR:   A1SJH0
- STRING:   A1SJH0
- GeneID:   4599792
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_2451
- eggNOG:   COG0140
- HOGENOM:   HBG646527
- OMA:   VWMAAEY
- ProtClustDB:   PRK00400
- BioCyc:   NSP35761:NOCA_2451-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01020
- InterPro:   IPR008179
- InterPro:   IPR021130
- TIGRFAMs:   TIGR03188

Pfam domain/function: PF01503 PRA-PH

EC number: =3.6.1.31

Molecular weight: Translated: 9548; Mature: 9548

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFDELWAELSEKARSRPEGSGTVRALDAGVHGIGKKLVEEAAESWMAAEHEGPERAAE
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EISQLLYHAQVLMLATGIDLDDVYAHL
HHHHHHHHHHHHHHHHCCCHHHHHHCC
>Mature Secondary Structure
MKTFDELWAELSEKARSRPEGSGTVRALDAGVHGIGKKLVEEAAESWMAAEHEGPERAAE
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EISQLLYHAQVLMLATGIDLDDVYAHL
HHHHHHHHHHHHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA