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The map label for this gene is aroC

Identifier: 119716639

GI number: 119716639

Start: 2572283

End: 2573461

Strand: Direct

Name: aroC

Synonym: Noca_2412

Alternate gene names: 119716639

Gene position: 2572283-2573461 (Clockwise)

Preceding gene: 119716638

Following gene: 119716640

Centisome position: 51.59

GC content: 74.55

Gene sequence:

>1179_bases
ATGCTGCGTTGGCTGACCGCGGGCGAGTCCCACGGCCCCTCTCTGGTCGCGATCCTCGAGGGGCTGCCCGCCCACGTCCA
GGTGACCTCCGACGACGTCGCGGACGCGCTGGCCCGGCGCCGGCTGGGCTACGGGCGCGGTGCGCGGATGAAGTTCGAGC
GCGACGAGGTGACGCTGGTCGGCGGCATCCGGCACGGCGAGACGATGGGTGGGCCGGTCGCGATCGAGATCGGCAACACC
GAGTGGCCGAAGTGGGAGAAGGTGATGGCGGCCGACCCGGTCGACCCCGTCGAGCTCGAGTCCCTGGCCCGCAACGCCCC
GCTCACCCGGCCCCGCCCCGGGCACGCCGACCTGGTCGGCATGCAGAAGTACGACTTCACCGAGGCCCGACCCATCCTCG
AGCGCGCCTCGGCCCGCGAGACCGCCGCCCGCGTGGCGCTCGGCCGGGTGGCGTCGAACCTGCTCGAGCAGGCGGTCGGT
GCCCGCATCGTCTCCCACGTCATCGAGCTCGGCGGCGTCCGCGCCCCGGCGGGCCTGTGGCCGCAACCCGAGGACGTCGA
CCGGCTCGACGACGACCCGGTCCGCTGCCTGGACGCCGACACCAGCAAGCTGATGGTCGAGGCGATCGACCAGGCCCACC
AGGACGGCGACACCCTCGGTGGTGTCGTCGAGGTCGTCGTCCACGGCCTGCCGCCGGGCCTGGGCTCGCACGTGCACTGG
GACCGGCGCCTCGACGCGCGCCTCGCGGGCGCGCTGATGGGCATCCAGGCGATCAAGGGGGTCGAGGTCGGCGACGGCTT
CGAGCTGGCGGCCACGCCGGGCTCGCGCGCCCACGACGAGATCGTCTCCGGCACGGACGGCCTGCGGCGGGTCAGCGGTC
GCTCCGGCGGCACCGAGGGCGGGATGAGCACCGGGGAGGTGCTCCGGGTCCGCGCCGCGATGAAGCCGATCGCCACGGTT
CCCCGCGCCCTGCGCACCGTGGACGTCGCCACCGGCGAGGCAGCGGTCGCCCACCACCAGCGCTCCGACGTCTGTGCCGT
GCCGGCCGCCGGGATCGTCGCCGAAGCGATGGTCGCGCTGGTGCTCGCCGACGCCGTCCTGGAGAAGTTCGGGGGCGACT
CGGTGCGCGAGACCCGCCGCAACGCGGAGGGCTACCTGGACACCCTGAGGTTCCGGTGA

Upstream 100 bases:

>100_bases
CGCCGGCGCGCTCGCGGGCGTCGTGCTCGGTCCGCTCTGGACCGGTCTCGCCTCGGGGTGACCGGCCCGGTCGGCGTACC
CCACGTGAAAGACTGACCCC

Downstream 100 bases:

>100_bases
CCGGACCCGCACGCCCCCGCGTCGTCCTGGTCGGGCCGATGGGGGCCGGCAAGACCACCGTCGCCCGGCTGCTGGCCGAC
GCCTGGGGCACCGGGGTCCG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MLRWLTAGESHGPSLVAILEGLPAHVQVTSDDVADALARRRLGYGRGARMKFERDEVTLVGGIRHGETMGGPVAIEIGNT
EWPKWEKVMAADPVDPVELESLARNAPLTRPRPGHADLVGMQKYDFTEARPILERASARETAARVALGRVASNLLEQAVG
ARIVSHVIELGGVRAPAGLWPQPEDVDRLDDDPVRCLDADTSKLMVEAIDQAHQDGDTLGGVVEVVVHGLPPGLGSHVHW
DRRLDARLAGALMGIQAIKGVEVGDGFELAATPGSRAHDEIVSGTDGLRRVSGRSGGTEGGMSTGEVLRVRAAMKPIATV
PRALRTVDVATGEAAVAHHQRSDVCAVPAAGIVAEAMVALVLADAVLEKFGGDSVRETRRNAEGYLDTLRFR

Sequences:

>Translated_392_residues
MLRWLTAGESHGPSLVAILEGLPAHVQVTSDDVADALARRRLGYGRGARMKFERDEVTLVGGIRHGETMGGPVAIEIGNT
EWPKWEKVMAADPVDPVELESLARNAPLTRPRPGHADLVGMQKYDFTEARPILERASARETAARVALGRVASNLLEQAVG
ARIVSHVIELGGVRAPAGLWPQPEDVDRLDDDPVRCLDADTSKLMVEAIDQAHQDGDTLGGVVEVVVHGLPPGLGSHVHW
DRRLDARLAGALMGIQAIKGVEVGDGFELAATPGSRAHDEIVSGTDGLRRVSGRSGGTEGGMSTGEVLRVRAAMKPIATV
PRALRTVDVATGEAAVAHHQRSDVCAVPAAGIVAEAMVALVLADAVLEKFGGDSVRETRRNAEGYLDTLRFR
>Mature_392_residues
MLRWLTAGESHGPSLVAILEGLPAHVQVTSDDVADALARRRLGYGRGARMKFERDEVTLVGGIRHGETMGGPVAIEIGNT
EWPKWEKVMAADPVDPVELESLARNAPLTRPRPGHADLVGMQKYDFTEARPILERASARETAARVALGRVASNLLEQAVG
ARIVSHVIELGGVRAPAGLWPQPEDVDRLDDDPVRCLDADTSKLMVEAIDQAHQDGDTLGGVVEVVVHGLPPGLGSHVHW
DRRLDARLAGALMGIQAIKGVEVGDGFELAATPGSRAHDEIVSGTDGLRRVSGRSGGTEGGMSTGEVLRVRAAMKPIATV
PRALRTVDVATGEAAVAHHQRSDVCAVPAAGIVAEAMVALVLADAVLEKFGGDSVRETRRNAEGYLDTLRFR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=369, Percent_Identity=34.6883468834688, Blast_Score=164, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6321290, Length=377, Percent_Identity=34.4827586206897, Blast_Score=192, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_NOCSJ (A1SJD2)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_923604.1
- ProteinModelPortal:   A1SJD2
- SMR:   A1SJD2
- STRING:   A1SJD2
- GeneID:   4598248
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_2412
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   NSP35761:NOCA_2412-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 41662; Mature: 41662

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRWLTAGESHGPSLVAILEGLPAHVQVTSDDVADALARRRLGYGRGARMKFERDEVTLV
CCEEECCCCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCCEEECCCCEEEE
GGIRHGETMGGPVAIEIGNTEWPKWEKVMAADPVDPVELESLARNAPLTRPRPGHADLVG
ECCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEC
MQKYDFTEARPILERASARETAARVALGRVASNLLEQAVGARIVSHVIELGGVRAPAGLW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PQPEDVDRLDDDPVRCLDADTSKLMVEAIDQAHQDGDTLGGVVEVVVHGLPPGLGSHVHW
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCH
DRRLDARLAGALMGIQAIKGVEVGDGFELAATPGSRAHDEIVSGTDGLRRVSGRSGGTEG
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCHHHHHHCCCCCCCCC
GMSTGEVLRVRAAMKPIATVPRALRTVDVATGEAAVAHHQRSDVCAVPAAGIVAEAMVAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEECCCHHHHHHHHHHHH
VLADAVLEKFGGDSVRETRRNAEGYLDTLRFR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRWLTAGESHGPSLVAILEGLPAHVQVTSDDVADALARRRLGYGRGARMKFERDEVTLV
CCEEECCCCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCCEEECCCCEEEE
GGIRHGETMGGPVAIEIGNTEWPKWEKVMAADPVDPVELESLARNAPLTRPRPGHADLVG
ECCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEC
MQKYDFTEARPILERASARETAARVALGRVASNLLEQAVGARIVSHVIELGGVRAPAGLW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PQPEDVDRLDDDPVRCLDADTSKLMVEAIDQAHQDGDTLGGVVEVVVHGLPPGLGSHVHW
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCH
DRRLDARLAGALMGIQAIKGVEVGDGFELAATPGSRAHDEIVSGTDGLRRVSGRSGGTEG
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCHHHHHHCCCCCCCCC
GMSTGEVLRVRAAMKPIATVPRALRTVDVATGEAAVAHHQRSDVCAVPAAGIVAEAMVAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEECCCHHHHHHHHHHHH
VLADAVLEKFGGDSVRETRRNAEGYLDTLRFR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA